2,468 research outputs found

    Recent advances in the treatment of acute myeloid leukemia

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    Acute myeloid leukemia (AML) is a disorder with significant molecular and clinical heterogeneity. Although there have been clear advances in the identification of somatic genetic and epigenetic alterations present in the malignant cells of patients with AML, translating this knowledge into an integrated view with an impact on the clinical treatment of AML has been slower to evolve. Recent clinical advances in the treatment of AML include studies demonstrating the benefit of dose-intense daunorubicin therapy in induction chemotherapy for patients of any age. We also review use of the DNA methyltransferase inhibitor azacitidine for treatment of AML in elderly patients as well as a study of global patterns of DNA methylation in patients with AML. Lastly, we review a recent assessment of the role of allogeneic hematopoietic stem cell transplantation in AML in first complete remission

    Growing irrigated lentil

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    Non-Peer ReviewedSince 1987, research was conducted at the Saskatchewan Irrigation Development Centre (SIDC), Outlook, to develop technology suitable for irrigated lentil (Lens culinaris Medikus) production. Diverse germplasm and various management practices were evaluated. Under irrigation, Eston, CDC Richlea, and Rose lentil produced higher seed yield than Laird. Supplemental irrigation of Eston produced marked yield increases in the low rainfall years. For example, in 1988 which received 95 mm (3.8 in) of precipitation during the growing season, addition of 130 mm (5.1 in) and 225 mm (8.9 in) of water produced approximately a 5-6 fold yield advantage. Excessive irrigation in wet years or at flowering reduced yield, likely through excessive vegetative growth and increased disease incidence. Under excess moisture conditions, Eston and Laird were more susceptible to diseases than CDC Richlea, or 458-57. Seeding rates (100 plants/m2, i.e. 9-10 plants/ft2) and row-spacing (20 em, i.e. 8 in) recommended for dryland production appeared suitable for irrigation although in one year, positive yield responses were obtained up to a population density of 175 plant/m2

    Analisis Pertumbuhan Lalu Lintas dan Perkiraan Volume Lalu Lintas Dimasa Mendatang Berdasarkan Volume Lalu Lintas Harian Rata - Rata (Studi Kasus Ruas Jalan SP. Lago-Sorek / Jalan Lintas Timur

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    Road planning techniques need some technical criteria to use as consideration for optimation of planning results to anticipate problems because of road, like social issues or technical issues. One of the criteria necessary planning is value of traffic growth. However, in developing countries including Indonesia, traffic analysis could support planning data with accuracy difficult that adequate. Because of lack of required data, so that difficult to predict future developments. This study aims to analyze value of traffic growth based on value of traffic volume from UR Research Institute survey on Sp. Lago - Sorek street in 2006 until 2013 without traffic volume data in 2008. And also to estimate the future of traffic volume on periods 5 years, 10 years, and 20 years later using value of the traffic growth and regression analysis method. The results show the value of traffic growth on Sp. Lago-Sorek street based on daily traffic volume average are 6.82% of total vehicle (kend/hari) and 4.12% for total vehicle (Smp/hari), traffic volume predicts of total vehicle based on value of traffic growth for year 2018 are 8429 (kend/hari) and 10050 (smp/hari), for year 2023 are 11721 (kend/hari) and 1230 (smp/hari), and for year 2033 are 22666 (kend/hari) and 10513 (smp/hari). Estimated volume of traffic Total Vehicles by regression analysis equation without traffic volume data in 2008 for year 2018 amount to 6915 (kend/hari) and 9239 (smp/hari), for year 2023 amount to 7480 (kend/hari) and 9759 (smp/hari), and for year 2033 amount to 8320 (kend/hari) and 10513 (smp/hari

    Analisis Kemampuan Keuangan Daerah Pemerintah Kabupaten Jayapura

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    The purpose of this paper is to analyze and obtain empirical evidence about the financial performance of Jayapura regency government in fiscal year 2010-2014, measured from the level of independence of local, regional dependency rate, the level of fiscal decentralization, the level of effectiveness and efficiency of financial management and fiscal capacity Jayapura regency in fiscal year 2010-2014, measured through share and growth Local Revenue. The results obtained from this study is that the financial capacity of Jayapura regency, measured from the level of the region's autonomy in fiscal year 2010-2014 included in the criteria are lacking, and the level of dependence of the region in that period qualifies as a very high criteria instructive relationship patterns. The ratio of fiscal decentralization is still lacking, the level of effectiveness of regional revenue in 2010-2014 classified in the category of very effective with a ratio of regional revenue collection efficiency is very efficient. The financial capacity of the district of Jayapura in this case the level of independence and dependence of the area and the level of fiscal decentralization is considered good if the government of Jayapura District has been able to raise the percentage of acceptance of regional revenue to be in the top 40% of the fund balance, because then the Local Revenue will contribute greater of the total regional expenditure. Keywords: financial capacity of local, regional autonomy, regional dependence, fiscal decentralization, effectiveness, efficienc

    Thermal wave resonant cavity technique in measuring thermal diffusivity of sucrose solution

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    The thermal-wave resonant cavity technique has been used to measure thermal diffusivity of sucrose solution with precision up to three-significant-figure. The thermal diffusivity of the solution decreases linearly with the increase of sucrose weight percentage and agrees to the simple mixture rule in the range up to a saturated point. Also the solution thermal diffusivity varies linearly with square FWHM. The thermal diffusivity value of water is very close to the literature value
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