Pharmacist professionals in the prevention of drug abuse: updating roles, and opportunities

The objective of this paper was to prepare and provide resources to pharmacists and other healthcare professionals, enabling them to carry out a critical analysis on drug abuse, acquiring knowledge in several areas that effectively contribute to their personal development in this professional field. Professionals play a crucial role in the reduction and prevention of substances abuse, since they are able to advise patient about illicit drugs, psychotropic medicines and alcohol abuse. There is an urgent need to specialize pharmacists to act in the national public health service and contribute to actions aimed at the surrounding community.Esse artigo tem o intuito de preparar e fornecer subsídios a farmacêuticos e outros profissionais de saúde a realizarem uma análise crítica sobre o abuso de drogas adquirindo conhecimento em diversas áreas que contribuam para o seu próprio desenvolvimento nesse campo de atuação. O profissional é fundamental na redução e prevenção ao abuso de substâncias, pois é capaz de aconselhar pacientes sobre o abuso de drogas ilícitas, medicamentos psicotrópicos e álcool. Há urgência na especialização de farmacêuticos para atuarem na saúde pública nacional contribuindo nas ações dirigidas à comunidade

Sexual aggression in the São Paulo nightlife scenarios: a public health concern

Departamento de Medicina Preventiva. Escola Paulista de Medicina. Universidade Federal de São Paulo, R Botucatu,740 Vila Clementino, BR-04023062 Sao Paulo, SP, BrazilDepartamento de Medicina Preventiva. Escola Paulista de Medicina. Universidade Federal de São Paulo, R Botucatu,740 Vila Clementino, BR-04023062 Sao Paulo, SP, Brazil.Web of Scienc

Uso de álcool, tabaco e outras drogas entre estudantes universitários brasileiros

BACKGROUND: Research has demonstrated that entrance into college is a critical period in which the student is vulnerable to initiating and continued alcohol and other drug usage. There have been large household surveys and surveys among high school students in Brazil during the last 20 years however, research regarding drug consumption among college students is represented by data solely from the last ten years. OBJECTIVES: The goal of this study was to review the evolution of these studies and to relate them to the principal results found in reference to the need for new research by which to profile university students with respect to drug consumption. METHODS: A literature review of the databases MEDLINE, LILACS, PubMed, and Scirus from 1997 to 2007. RESULTS: Twelve publications regarding drug consumption among Brazilian college students were found. They are presented as studies of prevalence in usage, and of risk behavior but, do not characterize this population faithfully. CONCLUSIONS: There is a need for further studies which allow comparisons between surveys in order to make adjustments in prevention programs of this community possible; that promote the improvement of quality of life; and that develop new preventive efforts. Follow-up surveys can bring new light to bear on how the variables behave over time and make tendency evaluations possible, which in turn could constitute studies in series.CONTEXTO: Pesquisas têm demonstrado que a entrada na universidade é um período crítico, de vulnerabilidade para o início e a manutenção do uso de álcool e outras drogas. No Brasil, grandes levantamentos domiciliares e entre estudantes do ensino médio foram realizados nos últimos 20 anos; porém, os levantamentos referentes ao consumo de drogas entre universitários são representados por dados dos últimos dez anos. OBJETIVOS: Revisar a evolução desses estudos e relacioná-los aos principais resultados encontrados, referindo a necessidade de novos levantamentos para estimativa do perfil e prevalência dos universitários diante do consumo de drogas no contexto estudado. MÉTODOS: Revisão bibliográfica das bases de dados MEDLINE, LILACS, PubMed e Scirus de 1997 a 2007. RESULTADOS: Foram encontradas 12 publicações referentes ao consumo de drogas entre universitários brasileiros. Estão apresentados como estudos de prevalência de uso e estudos de comportamentos de risco, os quais não caracterizam fidedignamente essa população. CONCLUSÕES: Há necessidade de estudos que viabilizem a comparação dos resultados, possibilitem adequações de programas de prevenção nessa comunidade, auxiliem na melhoria da qualidade de vida e desenvolvam novas frentes preventivas. A repetição poderá informar como as variáveis se comportam ao longo do tempo e se possibilitam avaliar tendências vindo a constituir estudos seriados

Cancer cases and deaths attributable to lifestyle risk factors in Chile

Abstract: Background: To identify modifiable risk factors that contribute to cancer holds important public health relevance for setting up prevention strategies. Therefore, the aim of this study was to estimate the proportion of cancer cases and deaths attributable to alcohol consumption, high body mass index (BMI), low fruits and vegetables consumption, lack of physical activity, tobacco smoking, and passive smoking in Chile in 2018. Methods: We retrieved data from a national representative survey to describe the distribution of six lifestyle risk factors. Relative risks of each risk factor-cancer pair were obtained from published meta-analysis and pooled cohort studies. Cancer cases and deaths were obtained from the GLOBOCAN 2018. Results: Nearly 30% of all cancer cases (15,097 out of 50,320 cases) and 36% of all cancer deaths (10,155 out of 28,010 deaths) in Chile in 2018 were attributable to lifestyle risk factors. Smoking and high BMI accounted for most of the cancer cases (9232 and 4394, respectively) and deaths (6868 and 2572). The cancer burden of other lifestyle risk factors varied by sex. In men, the proportion of all cancer cases attributed to alcohol were 3.7% compare to 2.0% for women. Cancers cases and deaths of the larynx, lung, oral/cavity, esophagus and bladder could be at least halved if lifestyle risk factors were eliminated. Conclusion: Smoking and high BMI were the leading causes of preventable cancer cases and deaths within the six lifestyles factors considered. Cancer prevention strategies should consider evidence-based interventions and public policies to encourage the adoption of a healthier lifestyle

Drug use in college students: a 13-year trend

OBJECTIVE: To analyze drug use trends among college students in 1996, 2001 and 2009. METHODS: A cross-sectional epidemiological study with a multistage stratified cluster sample with 9,974 college students was conducted in the city of São Paulo, southeastern Brazil. An anonymous self-administered questionnaire was used to collect information on drug use assessed in lifetime, the preceding 12 months and the preceding 30 days. The Bonferroni correction was used for multiple comparisons of drug use rates between surveys. RESULTS: There were changes in the lifetime use of tobacco and some other drugs (hallucinogens [6.1% to 8.8%], amphetamines [4.6% to 8.7%], and tranquilizers [5.7% to 8.2%]) from 1996 to 2009. Differences in the use of other drugs over the 12 months preceding the survey were also seen: reduced use of inhalants [9.0% to 4.8%] and increased use of amphetamines [2.4% to 4.8%]. There was a reduction in alcohol [72.9% to 62.1%], tobacco [21.3% to 17.2%] and marijuana [15.0% to 11.5%] use and an increase in amphetamine use [1.9% to 3.3%] in the preceeding 30 days. CONCLUSIONS: Over the 13-year study period, there was an increase in lifetime use of tobacco, hallucinogens, amphetamines, and tranquilizers. There was an increase in amphetamine use and a reduction in alcohol use during the preceding 12 months. There was an increase in amphetamine use during the preceding 30 days.OBJETIVO: Analizar la tendencia del uso de drogas entre universitarios en 1996, 2001 y 2009. MÉTODOS: estudio epidemiológico transversal con 9.974 universitarios del municipio de Sao Paulo, Sureste de Brasil, cuya muestra fue seleccionada por estratificación y conglomerados. Se adoptó instrumento de investigación de auto llenado, anónimo, que caracterizó el uso de drogas por tres medidas: uso en la vida, en los últimos 12 meses y en los últimos 30 días. Para comparar las frecuencias de uso de drogas entre las investigaciones, se utilizó la metodología de comparaciones múltiples con corrección de Bonferroni. RESULTADOS: Hubo reducción de la frecuencia de estudiantes que relataron consumo de drogas entre 1996 y 2009. Hubo disminución del uso de inhalantes y aumento en el uso de anfetamínicos en todas las medidas evaluadas [4,6% para 8,7% en la vida, de 2,4% para 4,5% en los últimos 12 meses y de 1,9% a 3,3% en los últimos 30 días]. Los alumnos de las Ciencias Humanas relataron uso de drogas con mayor frecuencia [48,6% en la vida, 29,0% en los últimos 12 meses y 20,9% en los últimos 30 días]. CONCLUSIONES: Entre los 13 años de estudio, hubo aumento de uso en la vida de cigarro, alucinógenos, anfetaminas y tranquilizantes; así como aumento en el uso de anfetaminas en los últimos 12 meses y disminución en el uso de alcohol. Con relación a los últimos 30 días, hubo aumento en el uso de anfetaminas.OBJETIVO: Analisar a tendência do uso de drogas entre universitários entre 1996, 2001 e 2009. MÉTODOS: Estudo epidemiológico transversal com 9.974 universitários do município de São Paulo, SP, cuja amostra foi selecionada por estratificação e conglomerados. Adotou-se instrumento de pesquisa de autopreenchimento, anônimo, que caracterizou o uso de drogas por três medidas: uso na vida, nos últimos 12 meses e nos últimos 30 dias. Para comparação de frequências de uso de drogas entre as pesquisas, utilizou-se a metodologia de comparações múltiplas com correção de Bonferroni. RESULTADOS: Houve redução da frequência de estudantes que relataram consumo de drogas entre 1996 e 2009. Houve diminuição do uso de inalantes e aumento do uso de anfetamínicos em todas as medidas avaliadas [4,6% para 8,7% na vida, de 2,4% para 4,5% nos últimos 12 meses e de 1,9% a 3,3% nos últimos 30 dias]. Os alunos das Ciências Humanas relataram uso de drogas com maior frequência [48,6% na vida, 29,0% nos últimos 12 meses e 20,9% nos últimos 30 dias]. CONCLUSÕES: Entre os 13 anos de estudo, houve aumento de uso na vida de tabaco, alucinógenos, anfetaminas e tranquilizantes; além do aumento do uso de anfetaminas nos últimos 12 meses e diminuição do uso de álcool. Em relação aos últimos 30 dias, houve aumento do uso de anfetaminas

Factores asociados a la reincidencia entre adolescentes mujeres en conflicto con la ley de una institución de Brasília, Distrito Federal, Brasil

A reincidência constitui um desafio para o sistema socioeducativo brasileiro por estar associada a fatores pessoais, sociais e ambientais, especialmente entre adolescentes em conflito com a lei. Este estudo verificou as principais características associadas à reincidência em uma amostra de 391 mulheres adolescentes em conflito com a lei em uma unidade de internação de Brasília, Distrito Federal, Brasil, entre 2004-2011. Dados transversais sociodemográficos acerca do uso de drogas e sobre as características do ato infracional foram analisados. Fatores associados à reincidência foram analisados por regressão binomial negativa. Trinta e dois vírgula cinco por cento das adolescentes pesquisadas eram reincidentes e a frequência média de reincidências foi de 2,16. Cinquenta e três vírgula seis por cento da amostra relataram uso de drogas. Após ajuste, reincidir foi positivamente associado à idade, uso de drogas, residência, tipo de ato infracional e não uso de drogas pela família. Nossos achados corroboram com outros contextos mundiais, demonstrando a necessidade de orientação nas intervenções adotadas pelo sistema socioeducativo brasileiro.Recidivism is a challenge for the Brazilian socio-educational system because it is associated with personal, social and environmental factors, especially among juvenile offenders. This study examined key characteristics and potential association with recidivism in 391 female adolescent offenders from a correctional institution in Brasília, Federal District, Brazil, between 2004 and 2011. Cross-sectional data on socio-demographics, drug use and offense characteristics from institutional information were examined. Associate factors with recidivism were examined using negative binomial regression analyses. 32.5% of offenders were recidivists at present admission and the mean frequency of recidivism among recidivists was 2.16. About half (53.6%) of the sample reported drug use. After the adjustment, recidivism was positively associated with: age; offender’s drug use; residence status; offense type; and no family drug use. Factors associated with juvenile offenders’ recidivism confirm findings from elsewhere, and should inform targeted interventions in Brazil.La reincidencia es un reto para el sistema socio-educativo brasileño. Este estudio examinó características claves y su posible asociación con la reincidencia de 391 adolescentes mujeres infractoras en una institución correccional en Brasília, Distrito Federal, Brasil, entre 2004 a 2011. Se examinaron datos transversales socio-demográficos, uso de drogas y las características del delito cometido a partir de la información institucional. Los factores asociados con la reincidencia se obtuvieron por análisis de regresión negativa-binomial. 32,5% de las internas eran reincidentes y la frecuencia media de reincidencia entre las reincidentes era de 2,16. Un 53,6% de la muestra informó consumo de drogas. Después del ajuste, la reincidencia se asoció positivamente con: edad; uso de drogas de la delincuente; estatus de residencia; tipo de delito; el no uso de drogas por parte de la familia. Los factores asociados con la reincidencia de las delincuentes confirman hallazgos de otros estudios, y deberían informar intervenciones específicas sobre esta población en Brasil

Including drugs and social vulnerability subjects in academic training through university extension project: the case of the University of Brasilia, Campus Ceilândia

Esse artigo tem como intuito apresentar a percepção dos participantes do Projeto de Extensão Roda de debate sobre crack, outras drogas e vulnerabilidades associadas, realizado na comunidade acadêmica com o objetivo de contribuir para criar, aperfeiçoar e constituir uma relação de comunicação constante e vinculada entre a universidade e a sociedade sobre o tema “drogas”. Para tal, foi realizada uma pesquisa de caráter misto sequencial, de amostra aleatória, com resultados quantitativos (obtidos por questionários de auto-relato dos alunos) e qualitativos (obtidos com auxílio de entrevista semiestruturada com mediador). Os resultados demonstraram, tanto na percepção discente quanto do mediador, que esse tipo de iniciativa gera conhecimento ao estudante da universidade sobre o tema e contribui na formação acadêmica. Pode-se concluir que a atividade de extensão foi considerada um espaço para desenvolver e estimular o conhecimento, além de auxiliar na formação acadêmica dos universitários, permitindo aos estudantes a reflexão crítica sobre o tema.This article aims to present and discuss the university extension project towards the academic community, entitled Roda de debate sobre crack, outras drogas e vulnerabilidades associadas, whose goal is to create, improve and support the dialogue between university and society over several issues on drugs.To this end, data was collected among participants, using a combined methodology of quantitative (self-report questionnaires) and qualitative (semi-structured interview by a mediator) perspectives. The results indicate that both students and mediators found that such activity increase general knowledge over drug issues among students, as well as contribute to academic training. In conclusion, this university extension activity was considered as a successful alternative to develop and stimulate knowledge and critical reflection

Prescribed use of methylphenidate hydrochloride and its correlates among Brazilian college students

Background: The prevalence of prescribed use of methylphenidate (MPH) and its correlates are not well-known in Brazil. Objective: To estimate the prevalence of prescribed use of MPH and its correlates in a sample of Brazilian college students. Methods: Twelve-thousand seven hundred and eleven college students filled out a drug use questionnaire. They were divided into two groups based on the lifetime use of MPH: MPH users (MPHU) and MPH non-users (MPHNU). Quasi-binomial regression models were carried out in order to evaluate the correlation among MPHU and other variables. Results: A lifetime use of MPH was reported from 0.9% of college students (MPHU). Being from the Midwest (PR = 4.8, p < 0.01) and South (PR = 5.2, p < 0.05), living in students housing (PR = 5.8, p < 0.001), prescribed use of amphetamines (PR = 8.9, p < 0.001) and benzodiazepines (< 3 weeks: PR = 4.4, p < 0.001; >= 3 weeks: PR = 6.7, p < 0.001), and harmful use of alcohol (PR = 4.0, p < 0.05) were correlated with MPHU. Discussion: The association of alcohol and drug use with prescribed use of MPH among college students suggests the importance of screening drinking patterns and use of other drugs among students with ADHD symptoms. Cesar ELR, et al. / Rev Psiq Clin. 2012; 39(6):183-

Uso prescrito de cloridrato de metilfenidato e correlatos entre estudantes universitários brasileiros

CONTEXTO: A prevalência do uso prescrito de metilfenidato (MPH) e correlatos ainda é pouco conhecida no Brasil. OBJETIVO: Estimar a prevalência do uso prescrito de MPH e correlatos em uma amostra populacional de universitários brasileiros. MÉTODOS: Doze mil setecentos e onze universitários foram solicitados a responder a um questionário sobre o uso de drogas. Em relação ao uso na vida de MPH, os universitários foram divididos em dois grupos: usuários de MPH (MPHU) e não usuários de MPH (MPHNU). Um modelo de regressão quasibinomial foi usado para avaliar a correlação desse uso com as demais variáveis. RESULTADOS: 0,9% dos universitários relataram ter feito uso de MPH na vida (MPHU). Ser da região Centro-Oeste (RP = 4,8; p < 0,01) e Sul (RP = 5,2; p < 0,05), morar em repúblicas (RP = 5,8; p < 0,001), já ter feito uso prescrito de anfetaminas (RP = 8,9; p < 0,001) e benzodiazepínicos (< 3 semanas: RP = 4,4; p < 0,001; &#8805; 3 semanas: RP = 6,7; p < 0,001) e fazer uso recente e de risco de álcool (RP = 4,0; p < 0,05) foram variáveis associadas ao MPHU. CONCLUSÃO: A associação do uso de álcool e de outras drogas com o uso prescrito de MPH entre universitários sugere a importância da triagem do padrão do uso de álcool e de outras drogas entre estudantes com sintomas de transtorno de déficit de atenção e hiperatividade (TDAH).BACKGROUND: The prevalence of prescribed use of methylphenidate (MPH) and its correlates are not well-known in Brazil. OBJECTIVE: To estimate the prevalence of prescribed use of MPH and its correlates in a sample of Brazilian college students. METHODS: Twelve-thousand seven hundred and eleven college students filled out a drug use questionnaire. They were divided into two groups based on the lifetime use of MPH: MPH users (MPHU) and MPH non-users (MPHNU). Quasi-binomial regression models were carried out in order to evaluate the correlation among MPHU and other variables. RESULTS: A lifetime use of MPH was reported from 0.9% of college students (MPHU). Being from the Midwest (PR = 4.8, p < 0.01) and South (PR = 5.2, p < 0.05), living in students housing (PR = 5.8, p < 0.001), prescribed use of amphetamines (PR = 8.9, p < 0.001) and benzodiazepines (< 3 weeks: PR = 4.4, p < 0.001; &#8805; 3 weeks: PR = 6.7, p < 0.001), and harmful use of alcohol (PR = 4.0, p < 0.05) were correlated with MPHU. DISCUSSION: The association of alcohol and drug use with prescribed use of MPH among college students suggests the importance of screening drinking patterns and use of other drugs among students with ADHD symptoms

Drug use in college students: a 13-year trend

OBJECTIVE: To analyze drug use trends among college students in 1996, 2001 and 2009. METHODS: A cross-sectional epidemiological study with a multistage stratified cluster sample with 9,974 college students was conducted in the city of Sao Paulo, southeastern Brazil. An anonymous self-administered questionnaire was used to collect information on drug use assessed in lifetime, the preceding 12 months and the preceding 30 days. The Bonferroni correction was used for multiple comparisons of drug use rates between surveys. RESULTS: There were changes in the lifetime use of tobacco and some other drugs (hallucinogens [6.1% to 8.8%], amphetamines [4.6% to 8.7%], and tranquilizers [5.7% to 8.2%]) from 1996 to 2009. Differences in the use of other drugs over the 12 months preceding the survey were also seen: reduced use of inhalants [9.0% to 4.8%] and increased use of amphetamines [2.4% to 4.8%]. There was a reduction in alcohol [72.9% to 62.1%], tobacco [21.3% to 17.2%] and marijuana [15.0% to 11.5%] use and an increase in amphetamine use [1.9% to 3.3%] in the preceeding 30 days. CONCLUSIONS: Over the 13-year study period, there was an increase in lifetime use of tobacco, hallucinogens, amphetamines, and tranquilizers. There was an increase in amphetamine use and a reduction in alcohol use during the preceding 12 months. There was an increase in amphetamine use during the preceding 30 days.Secretaria Nacional de Politicas sobre Drogas [9/2008]Secretaria Nacional de Politicas sobre DrogasFundacao de Amparo a Pesquisa do Estado de Sao Paulo (Foundation of the State of Sao Paulo FAPESP)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (Foundation of the State of Sao Paulo - FAPESP) [09/51.901-2, 2008/55.550-7