336 research outputs found
Saturated fat enhances incorporation of n-3 polyunsaturated fatty acids into plasma and erythrocyte lipids in healthy humans
The effectiveness of idea capture schemes
Innovation at work is mainly driven by employees' ideas. This paper reports a study of the effectiveness (e.g., rate of suggestion making) of schemes for capturing these ideas. Based on a survey of 182 UK organizations, the study shows that decentralized suggestion schemes and work-based systems are more effective than centralized and informal schemes. The extent of planning, publicity, feedback and management support given to the scheme, and the type of reward offered to employees, also independently account for variation in effectiveness. Publicity and non-monetary rewards, though, are found to be most decisive, regardless of scheme type. Learning culture also affects the rate of suggestion making, though the effect is greater for centralized and decentralized schemes than for the others. The key implication of the findings is that by paying particular attention to how they are advertised and how participation is rewarded, organizations could improve the return on their idea capture schemes
Global sensitivity analysis of stochastic computer models with joint metamodels
The global sensitivity analysis method used to quantify the influence of uncertain input variables on the variability in numerical model responses has already been applied to deterministic computer codes; deterministic means here that the same set of input variables gives always the same output value. This paper proposes a global sensitivity analysis methodology for stochastic computer codes, for which the result of each code run is itself random. The framework of the joint modeling of the mean and dispersion of heteroscedastic data is used. To deal with the complexity of computer experiment outputs, nonparametric joint models are discussed and a new Gaussian process-based joint model is proposed. The relevance of these models is analyzed based upon two case studies. Results show that the joint modeling approach yields accurate sensitivity index estimatiors even when heteroscedasticity is strong
Efeito da substituição do farelo de algodão pelo farelo de canola no desempenho de novilhas Nelore confinadas
Spatializing the Ecological Leviathan: Territorial Strategies and the Production of Regional Natures
This paper explores a dual absence – the absence of the state within contemporary geographical analyses of nature; and the absence of nature within contemporary explorations of state power. We argue that the modern state continues to play a crucial role in framing social interactions with nature, while nature is still vital to states within their realization of different forms of material and ideological power. In order to reconnect analyses of the state and nature, this paper combines work on the production of nature and state strategy with Lefebvre’s recently translated writings on state space and territory. By focusing on the production of territory (or state space), we explore the interaction of the state and nature in the context of the political management of social and ecological space. We unravel the spatial entanglements of the state and nature through an analysis of the British state’s territorial strategies within the West Midlands region. By considering three key historical periods within the history of the West Mid-lands we reveal how the emergence of the regional space called the West Midlands is a product of the ongoing spatial dialectics of state and nature therein
A heat-stable microparticle platform for oral micronutrient delivery
Micronutrient deficiencies affect up to 2 billion people and are the leading cause of cognitive and physical disorders in the developing world. Food fortification is effective in treating micronutrient deficiencies; however, its global implementation has been limited by technical challenges in maintaining micronutrient stability during cooking and storage. We hypothesized that polymer-based encapsulation could address this and facilitate micronutrient absorption. We identified poly(butylmethacrylate-co-(2-dimethylaminoethyl)methacrylate-co-methylmethacrylate) (1:2:1) (BMC) as a material with proven safety, offering stability in boiling water, rapid dissolution in gastric acid, and the ability to encapsulate distinct micronutrients. We encapsulated 11 micronutrients (iron; iodine; zinc; and vitamins A, B2, niacin, biotin, folic acid, B12, C, and D) and co-encapsulated up to 4 micronutrients. Encapsulation improved micronutrient stability against heat, light, moisture, and oxidation. Rodent studies confirmed rapid micronutrient release in the stomach and intestinal absorption. Bioavailability of iron from microparticles, compared to free iron, was lower in an initial human study. An organotypic human intestinal model revealed that increased iron loading and decreased polymer content would improve absorption. Using process development approaches capable of kilogram-scale synthesis, we increased iron loading more than 30-fold. Scaled batches tested in a follow-up human study exhibited up to 89% relative iron bioavailability compared to free iron. Collectively, these studies describe a broad approach for clinical translation of a heat-stable ingestible micronutrient delivery platform with the potential to improve micronutrient deficiency in the developing world. These approaches could potentially be applied toward clinical translation of other materials, such as natural polymers, for encapsulation and oral delivery of micronutrients
Cosmological perturbations in SFT inspired non-local scalar field models
We study cosmological perturbations in models with a single non-local scalar
field originating from the string field theory description of the rolling
tachyon dynamics. We construct the equation for the energy density
perturbations of the non-local scalar field and explicitly prove that for the
free field it is identical to a system of local cosmological perturbation
equations in a particular model with multiple (maybe infinitely many) local
free scalar fields.Comment: 21 pages, no figures, v3: presentation improved, results unchanged,
references adde
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