104,936 research outputs found

    The prevention and treatment of childhood obesity.

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    The effectiveness of interventions used in the prevention and treatment of childhood obesity published in a recent issue of Effective Heath Care is reviewed

    Sickness certification system in the United Kingdom: qualitative study of views of general practitioners in Scotland

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    Objectives: To explore how general practitioners operate the sickness certification system, their views on the system, and suggestions for change. Design: Qualitative focus group study consisting of 11 focus groups with 67 participants. Setting: General practitioners in practices in Glasgow, Tayside, and Highland regions, Scotland. Sample: Purposive sample of general practitioners, with further theoretical sampling of key informant general practitioners to examine emerging themes. Results: General practitioners believed that the sickness certification system failed to address complex, chronic, or doubtful cases. They seemed to develop various operational strategies for its implementation. There appeared to be important deliberate misuse of the system by general practitioners, possibly related to conflicts about roles and incongruities in the system. The doctor-patient relationship was perceived to conflict with the current role of general practitioners in sickness certification. When making decisions about certification, the general practitioners considered a wide variety of factors. They experienced contradictory demands from other system stakeholders and felt blamed for failing to make impossible reconciliations. They clearly identified the difficulties of operating the system when there was no continuity of patient care. Many wished either to relinquish their gatekeeper role or to continue only with major changes. Conclusions: Policy makers need to recognise and accommodate the range and complexity of factors that influence the behaviour of general practitioners operating as gatekeepers to the sickness certification system, before making changes. Such changes are otherwise unlikely to result in improvement. Models other than the primary care gatekeeper model should be considered

    Performance characteristics of a thermionic converter with a /110/ tungsten emitter and a collector of niobium with trace amounts of tungsten and niobium carbide on the surface

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    Comparison of thermionic tungsten /110/ converter performances with niobium collectors and nickel collectors at various emitter, collector and cesium reservoir temperature

    Characteristics of a thermionic converter with a chloride vapor deposited tungsten emitter /110/ and a collector of molybdenum deposited on niobium

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    Performance characteristics of parallel plane, variable spaced thermionic converter with tungsten emitter and molybdenum-niobium collecto

    Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni

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    Lung-stage schistosomula are the target of protective immunity in mice vaccinated with attenuated cercariae of Schistosoma mansoni. Therefore, proteins present at this developmental stage, and in particular those which are secreted, are a potential source of novel vaccine candidates. However, little information is available about such molecules. Here we describe the cDNA clones identified by screening expression libraries with serum raised against proteins released by lung-stage schistosomula. In total, 11 different cDNA species were identified, 6 of which have been described previously in S. mansoni; these included fructose 1,6-bisphosphate aldolase and Sm21.7 which together accounted for two-thirds of all positive clones. Of the 5 newly described schistosome genes, 1 cDNA had a high degree of homology to the s5a subunit of 26S proteasomes, most significant being with the human protein. The remaining 4 clones showed no significant homologies to any genes sequenced previously. Fructose 1,6-bisphosphate aldolase, Sm21.7, the proteasome homologue and 1 unknown clone (A26) have been expressed in a bacterial expression system and serum produced against each recombinant protein. Immunolocalization showed fructose 1,6-bisphosphate aldolase, Sm21.7 and the proteasome homologue to be most abundant in muscle cells whilst clone A26 was distributed throughout many tissues, but was most abundant in the tegument. Analysis of the cellular immune responses of vaccinated mice showed 3 of the 4 expressed clones to be highly immunogenic, inducing the secretion of large quantities of the Th1-type cytokine interferon gamma

    Methods of resistance estimation in permanent magnet synchronous motors for real-time thermal management

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    Real-time thermal management of electrical ma- chines relies on sufficiently accurate indicators of internal tem- perature. One indicator of temperature in a permanent-magnet synchronous motor (PMSM) is the stator winding resistance. Detection of PMSM winding resistance in the literature has been made on machines with relatively high resistances, where the resistive voltage vector is significant under load. This paper describes two techniques which can be applied to detect the winding resistance, through ‘Fixed Angle’ and ‘Fixed Mag- nitude’ current injection. Two further methods are described which discriminate injected current and voltages from motoring currents and voltages: ‘Unipolar’ and ‘Bipolar’ separation. These enable the resistance to be determined, and hence the winding temperature in permanent-magnet machines. These methods can be applied under load, and in a manner that does not disturb motor torque or speed. The method distinguishes between changes in the electro-motive force (EMF) constant and the resistive voltage. This paper introduces the techniques, whilst a companion paper covers the application of one of the methods to a PMSM drive system

    Characteristics of a thermionic converter with a chloride vapor deposited tungsten emitter /110/ and a nickel collector

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    Thermionic coverter with chloride vapor deposited tungsten emitter and nickel collecto

    Index theorems for quantum graphs

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    In geometric analysis, an index theorem relates the difference of the numbers of solutions of two differential equations to the topological structure of the manifold or bundle concerned, sometimes using the heat kernels of two higher-order differential operators as an intermediary. In this paper, the case of quantum graphs is addressed. A quantum graph is a graph considered as a (singular) one-dimensional variety and equipped with a second-order differential Hamiltonian H (a "Laplacian") with suitable conditions at vertices. For the case of scale-invariant vertex conditions (i.e., conditions that do not mix the values of functions and of their derivatives), the constant term of the heat-kernel expansion is shown to be proportional to the trace of the internal scattering matrix of the graph. This observation is placed into the index-theory context by factoring the Laplacian into two first-order operators, H =A*A, and relating the constant term to the index of A. An independent consideration provides an index formula for any differential operator on a finite quantum graph in terms of the vertex conditions. It is found also that the algebraic multiplicity of 0 as a root of the secular determinant of H is the sum of the nullities of A and A*.Comment: 19 pages, Institute of Physics LaTe
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