Diffractive parton distributions: the role of the perturbative Pomeron

We consider the role of the perturbative Pomeron-to-parton splitting in the formation of the diffractive parton distributions.Comment: 8 pages, 4 figures. To appear in the proceedings of the 12th International Conference on Elastic and Diffractive Scattering: Forward Physics and QCD, DESY, Hamburg, Germany, 21-25 May 200

Ion distribution and temperature in the topside ionosphere obtained from the Alouette satellite

Ion distribution and temperature of topside ionosphere from electron density measurements by Alouette satellit

Transient activaton of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

When β-catenin signalling is disturbed from mid-gestation onwards lineage commitment is profoundly altered in postnatal mouse epidermis. We have investigated whether adult epidermis has the capacity for β-catenin-induced lineage conversion without prior embryonic priming. We fused N-terminally truncated, stabilised β-catenin to the ligand-binding domain of a mutant oestrogen receptor (ΔNβ -cateninER). ΔNβ-cateninER was expressed in the epidermis of transgenic mice under the control of the keratin 14 promoter and β -catenin activity was induced in adult epidermis by topical application of 4-hydroxytamoxifen (4OHT). Within 7 days of daily 4OHT treatment resting hair follicles were recruited into the hair growth cycle and epithelial outgrowths formed from existing hair follicles and from interfollicular epidermis. The outgrowths expressed Sonic hedgehog, Patched and markers of hair follicle differentiation, indicative of de novo follicle formation. The interfollicular epidermal differentiation program was largely unaffected but after an initial wave of sebaceous gland duplication sebocyte differentiation was inhibited. A single application of 4OHT was as effective as repeated doses in inducing new follicles and growth of existing follicles. Treatment of epidermis with 4OHT for 21 days resulted in conversion of hair follicles to benign tumours resembling trichofolliculomas. The tumours were dependent on continuous activation of β-catenin and by 28 days after removal of the drug they had largely regressed. We conclude that interfollicular epidermis and sebaceous glands retain the ability to be reprogrammed in adult life and that continuous β-catenin signalling is required to maintain hair follicle tumours.Peer reviewedFinal Published versio

Influences of lateral preference and personality on behaviour towards a manual sorting task

Differences in task behaviour between left- and right-handers and left- and right-eared individuals have been reported (e.g. Jackson, 2008 and Wright et al., 2004) with left-handers taking longer to begin a task and right-eared individuals having a more disinhibited approach. Personality measurements are also important when examining approach behaviour. Jackson (2008) reported that those with higher neuroticism levels and a right-ear preference react faster to tasks. The current study investigated the effects of lateral preference and personality on behaviour towards a manual sorting task. Eighty-five participants completed laterality and personality scales and a card-sorting task. Degree of hand preference was found to influence behaviour towards the task with strong left-handers taking longer to begin. Those with a left congruent lateral preference (left-hand, left-ear) took significantly longer to begin the task than those with a right congruent preference. Neither neuroticism nor extraversion influenced task approach. We concluded that hand preference, and more specifically a strong left-hand preference is a good predictor of a longer initiation time on a manual task. Ear preference on its own does not predict initiation time

A perfect storm: An archaeological management crisis in the Mississippi River Delta

Engineered projects resulting in unintended consequences, coastal erosion, subsidence, and sea-level rise are rapidly destroying archaeological sites in the Mississippi River Delta (MRD). The processes of site obliteration are intensifying and accelerating due to anthropogenic transformation of the environment, including cumulative engineered alterations of the landscape and climate change. Combined with increased inundation and erosion from storm surges, hundreds of terrestrial sites formerly located on natural levees, barrier islands, and other coastal landforms are progressively eroded, redeposited, deeply buried, and submerged. These include thousand-year-old earthen mounds and shell middens constructed by Native Americans, as well as centuries-old fishing communities along the coast. These irreplaceable cultural properties can provide crucial information on the unique history and ecology of the MRD. Ongoing studies include consulting with interested parties and implementing data sharing agreements. Re- searchers have formed a consortium of universities and state and federal agencies, and are partnering with culturally affiliated Native American tribes, descendant groups, and coastal communities. The consortium is developing a robust GIS-enabled risk matrix for analyzing threats and effects to endangered sites. It is using the risk matrix to select 30 sites for monitoring, assessment, aerial photogrammetry, and recording environmental data on water table fluctuations. Analysis of action-based scientific data on these imperiled and rapidly disappearing places is urgently needed and will provide the impetus and baseline for future studies. Otherwise, ongoing site destruction will erase any remaining opportunities for learning about Louisiana’s deep history and diverse cultural heritage

A comparison of ultrasonic and mechanical stadiometry

AIM: To compare an ultrasonic height measuring device (Gulliver) with mechanical stadiometry and the classical "book and tape measure" method. METHODS: Blinded duplicate measurements of height were made on each of 14 children by a pair of observers using a stadiometer (H) and Gulliver (G). Height was measured on a further 18 children by parents and an auxologist using Gulliver and the book and tape method (TM), and the results were compared with those obtained with a single stadiometry measurement. Finally, measurement of a rigid metal box was made on 10 occasions by the three methods. RESULTS: In the group of 14 children, the mean difference (range) in height (H minus G) was +2.8 cm (+0.5 to +4.55 cm), with H giving a systematically higher value in 276 of 280 individual measurements. In the group of 18 children, height by H was greater than by G or TM in 47 of 52 individual measurements. The mean (SD) height of the box by H (61.60 (0.07) cm) was greater than by G (60.96 (0.15) cm; p 0.05). G and TM produced three times less reliable estimations of height than H, but with a large difference in cost, and there was evidence of systematic underrecording of height by 0.5 cm with G. CONCLUSIONS: Stadiometry is precise and reproducible, and can detect true changes in height over one month periods in mid-childhood, and should remain the standard way of observing growth. The book and tape method can produce clinically acceptable quarterly estimations of height that can be performed in the home