77 research outputs found
Intrinsic decoherence and classical-quantum correspondence in two coupled delta-kicked rotors
We show that classical-quantum correspondence of center of mass motion in two
coupled delta-kicked rotors can be obtained from intrinsic decoherence of the
system itself which occurs due to the entanglement of the center of mass motion
to the internal degree of freedom without coupling to external environment
Chaos and Quantum-Classical Correspondence via Phase Space Distribution Functions
Quantum-classical correspondence in conservative chaotic Hamiltonian systems
is examined using a uniform structure measure for quantal and classical phase
space distribution functions. The similarities and differences between quantum
and classical time-evolving distribution functions are exposed by both
analytical and numerical means. The quantum-classical correspondence of
low-order statistical moments is also studied. The results shed considerable
light on quantum-classical correspondence.Comment: 16 pages, 5 figures, to appear in Physical Review
Characteristics of Quantum-Classical Correspondence for Two Interacting Spins
The conditions of quantum-classical correspondence for a system of two
interacting spins are investigated. Differences between quantum expectation
values and classical Liouville averages are examined for both regular and
chaotic dynamics well beyond the short-time regime of narrow states. We find
that quantum-classical differences initially grow exponentially with a
characteristic exponent consistently larger than the largest Lyapunov exponent.
We provide numerical evidence that the time of the break between the quantum
and classical predictions scales as log(), where is
a characteristic system action. However, this log break-time rule applies only
while the quantum-classical deviations are smaller than order hbar. We find
that the quantum observables remain well approximated by classical Liouville
averages over long times even for the chaotic motions of a few
degree-of-freedom system. To obtain this correspondence it is not necessary to
introduce the decoherence effects of a many degree-of-freedom environment.Comment: New introduction, accepted in Phys Rev A (May 2001 issue), 12 latex
figures, 3 ps figure
Chromosome 11q13.5 variant associated with childhood eczema:an effect supplementary to filaggrin mutations
BackgroundAtopic eczema is a common inflammatory skin disease with multifactorial etiology. The genetic basis is incompletely understood; however, loss of function mutations in the filaggrin gene (FLG) are the most significant and widely replicated genetic risk factor reported to date. The first genome-wide association study in atopic eczema recently identified 2 novel genetic variants in association with eczema susceptibility: a single nucleotide polymorphism on chromosome 11q13.5 (rs7927894) and a single nucleotide polymorphism (rs877776) within the gene encoding hornerin on chromosome 1q21.ObjectiveTo test the association of these 2 novel variants with pediatric eczema and to investigate their interaction with FLG null mutations.MethodsCase-control study to investigate the association of rs7927894, rs877776 and the 4 most prevalent FLG null mutations with moderate-severe eczema in 511 Irish pediatric cases and 1000 Irish controls. Comprehensive testing for interaction between each of the loci was also performed.ResultsThe association between rs7927894 and atopic eczema was replicated in this population (P = .0025, χ2 test; odds ratio, 1.27; 95% CI, 1.09-1.49). The 4 most common FLG null variants were strongly associated with atopic eczema (P = 1.26 × 10−50; combined odds ratio, 5.81; 95% CI, 4.51-7.49). Interestingly, the rs7927894 association was independent of the well-established FLG risk alleles and may be multiplicative in its effect. There was no significant association between rs877776 and pediatric eczema in this study.ConclusionSingle nucleotide polymorphism rs7927894 appears to mark a genuine eczema susceptibility locus that will require further elucidation through fine mapping and functional analysis
Skin microbiome prior to development of atopic dermatitis:early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year
Background: Disease flares of established atopic dermatitis (AD) are generally associated with a low-diversity skin microbiota and Staphylococcus aureus dominance. The temporal transition of the skin microbiome between early infancy and the dysbiosis of established AD is unknown. Methods: We randomly selected 50 children from the Cork Babies After SCOPE: Evaluating the Longitudinal Impact Using Neurological and Nutritional Endpoints (BASELINE) longitudinal birth cohort for microbiome sampling at 3 points in the first 6 months of life at 4 skin sites relevant to AD: the antecubital and popliteal fossae, nasal tip, and cheek. We identified 10 infants with AD and compared them with 10 randomly selected control infants with no AD. We performed bacterial 16S ribosomal RNA sequencing and analysis directly from clinical samples. Results: Bacterial community structures and diversity shifted over time, suggesting that age strongly affects the skin microbiome in infants. Unlike established AD, these patients with infantile AD did not have noticeably dysbiotic communities before or with disease and were not colonized by S aureus. In comparing patients and control subjects, infants who had affected skin at month 12 had statistically significant differences in bacterial communities on the antecubital fossa at month 2 compared with infants who were unaffected at month 12. In particular, commensal staphylococci were significantly less abundant in infants affected at month 12, suggesting that this genus might protect against the later development of AD. Conclusions: This study suggests that 12-month-old infants with AD were not colonized with S aureus before having AD. Additional studies are needed to confirm whether colonization with commensal staphylococci modulates skin immunity and attenuates development of AD
Letters from the Aegean. By James Emerson Esq.
Preface: Emerson, James (esq.)Dedication: Rev. John O. OldfieldContent description: IndexIllustration: 2 (Maps ,Views ,)Pagination: PP16+244P, PP8+266PVolumes: 2Text Genre:LettersIllustration: 2 (χάρτες ,τοπία ,
Tableau de la Grèce en 1825, ou récit des voyages de M.J. Emerson et du Cte Pecchio, traduit de l' Anglais ... et augmenté d’un précis des événemens qui ont eu lieu depuis le départ de ces voyageurs jusqu' à ce jour.
Preface: Cohen ,JeanAppendix.Dedication:Content description: Detailed contentsIllustration: 1 (varia ,)Pagination: PP18+464PVolumes: 1Text Genre:Journal / ProseIllustration: 1 (άλλα θέματα ,
A Picture of Greece in 1825; as exhibited in the personal narratives of.... comprising a detailed account of the events of the late campaign, and sketches of the principal military, naval, and political chiefs.
Preface: Colburn H., EmersonIntroduction: Pecchio Giuseppe, Humphreys W.H.Dedication:Content description: Detailed contentsIllustration: (varia ,)Pagination: PP11+359P, PP8+344PVolumes: 2Text Genre:Journal / ProseIllustration: (άλλα θέματα ,
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