Physically-Realizable Uniform Temperature Boundary Condition Specification on a Wall of an Enclosure: Part I – Problem Investigation

Designing an experimental apparatus requires considerable amount of planning. Despite proper planning, one can easily overlook a design such as the standard uniform temperature boundary condition applied to all or portion of a wall of an experimental apparatus. Although this boundary condition is mathematically simple and precise, achieving it physically may not be that simple. This paper addresses one such three-dimensional natural convection heat transfer apparatus that was designed to measure benchmark Nusselt numbers at various Rayleigh numbers with uniform temperatures specified at two walls of the enclosure. It was found that the effect of thermal spreading/constriction resistance on one wall where this uniform temperature condition was prescribed was significant, and as a result, the uniform temperature profile based on the initial design was not physically achieved. In support of this non-uniform temperature observation, this paper presents a thermal resistance model of a plate (which is a portion of this overall heat transfer apparatus) to explain the observed temperature non-uniformity. The results obtained from the current model are validated with measured data, and in terms of a temperature difference between two locations on the plate, the approximate analytical solution is well within the experimental error of 0.03K

Physically-Realizable Uniform Temperature Boundary Condition Specification on a Wall of an Enclosure: Part II – Problem Solution

Temperature measurements along one side of the rectangular plate showed severe temperature non-uniformity along one side of a wall of a cubical experimental apparatus where the uniform temperature was physically desired. Despite proper planning and analyses, this non-uniformity was high enough that a benchmark study could not be carried out to the desired accuracy of about one percent error. This paper presents and extends analyses made previously based on the modifications to the original design of the apparatus to reduce the temperature non-uniformity on the wall by adding an auxiliary heater around a wall where the uniform temperature was desired. A detailed mathematical analysis shows significant reduction in temperature non-uniformity from about four percent (based on the initial design) to less than one percent (for the modified design). By examining the temperature difference between two locations on the plate, the predicted temperature difference obtained through mathematical analyses show excellent agreement with the measured temperature difference. The temperature non-uniformity along the boundary of a wall was reduced to less than one percent of the overall temperature difference

EFFECTS OF REHABILITATION ON BACK MUSCLE CONTRACTION PATTERNS OF LOW BACK PAIN PATIENTS

The aims of this study were to conduct a comparative investigation of muscle function between low back pain (LBP) patients and normal subjects, as well as to explore whether intensive rehabilitation can change back muscle contraction synergy. 20 normal subjects and 20 patients with chronic LBP were asked to perform symmetrical and asymmetrical tasks. LBP patients were tested in the weeks immediately before and after 12-week LBP rehabilitation treatment. Tasks include “carrying” weights up and down with a 45° left rotation. Eight channel surface EMG electrodes were placed on the surface of paraspinal muscles. correlation between right and left corresponding muscles as well as between pre- and post-treatment were calculated. Lifting capacity for LBP patients were also measured before and after treatment. EMG profiles showed that the muscle activity strategies varied between normal subjects and LBP patients. The correlation coefficients for spinal muscles have shown very reproducible intra-subject muscle contraction synergies. Unbalanced EMG patterns found in LBP patients under symmetrical tasks were not affected by rehabilitation treatment

Synergistic co-cultivation of activated sludge and microalgae in enhancing lipid production and N-laden wastewater treatment

The influence of inoculation ratios of activated sludge and microalgae were investigated in this study in the aspects of biomass yield, lipid yield and total nitrogen (TN) removal efficiency. It was observed that mixed culture of activated sludge/microalgae with the ratio 1:1 and 1:0.75 achieved a maximum lipid production up to 0.144 g/L and 0.133 g/L as compared with microalgae culture alone, which was only 0.081 g/L. The highest total nitrogen (TN) removal was observed with 1:1 and 1:0.75 ratios of activated sludge/microalgae cultures ranging from 96.3-96.9% removal efficiency, which was an improvement of about 90% removal efficiency compared to the activated sludge culture (6.25±0.08%). The flocculation efficiency was generally improved in mixed cultures of activated sludge andmicroalgae in comparison with only activated sludge culture and microalgae culture alone.Keywords: activated sludge; microalgae; co-cultivation; lipid; nitrogen removal

Bioinformatics for Membrane Lipid Simulations: Models, Computational Methods, and Web Server Tools

Biological membranes are complex environments consisting of different types of lipids and membrane proteins. The structure of a lipid bilayer is typically difficult to study because the membrane liquid crystalline state is made up of multiple disordered lipid molecules. This complicates the description of the lipid membrane properties by the conformation of any single lipid molecule. Molecular dynamics (MD) simulations have been used extensively to investigate properties of membrane lipids, lipid vesicles, and membrane protein systems. All-atom membrane models can elucidate detailed contacts between membrane proteins and its surrounding lipids, while united-atom and coarse-grained description have allowed larger models and longer timescales up to microsecond mark to be probed. Additionally, membrane models with mixed phospholipids and lipopolysaccharide content have made it possible to model improved views of biological membranes. Here, we present an overview of commonly used lipid force fields by the biosimulation community, useful tools for membrane MD simulations, and recent advances in membrane simulations

Removal and transformation of hexavalent chromium in sequencing batch reactor

The objectives of this study are to evaluate the efficiency of removal of hexavalent chromium (Cr(VI)) in a sequencing batch reactor (SBR) and to ascertain the fate of Cr(VI) in the treatment process. An SBR was operated with the FILL, REACT, SETTLE, DRAW and IDLE periods in the time ratio of 2:12:2:1.5:6.5 for a cycle time of 24 h. The study was divided into 5 phases with the addition of 0.5, 2.0, 3.0 and 5.0 mg/ℓ of Cr(VI) in Phases II, III, IV and V for a duration of 46, 75, 43 and 16 operational cycles, respectively. The Cr(VI) removal efficiencies for SBR were found to be 79.8, 88.4 and 99.8% in Phases III, IV and V, respectively. The results revealed that Cr(VI) removal efficiency improved with acclimated activated sludge. Determination of Cr in the suspended sludge showed that around 95% of the Cr species were Cr(III). Determination of Cr concentration profiles during the FILL and REACT periods showed that the predominant species was Cr(III) as Cr(VI) was bio-reduced. The proposed Cr(VI) removal mechanism involves bioreduction to Cr(III) which was subsequently precipitated and adsorbed by activated sludge. Precipitation rather than sorption is envisaged to be the main path of removal of Cr(III) from the solution.Keywords: Sequencing batch reactor, hexavalent chromium, removal, transformation, mechanis

MICROFRACTURE OF HUMAN THORACOLUMBAR VERTEBRAL BODY UNDER FATIGUE LOADING

The purpose of this study was to investigate the relationship between lumbar vertebral microfracture and fatigue loading on young human spine under physiological cyclic compression loads. Thirty-three thoracolumbar vertebrae (T12 to L4) were obtained from 7 adult Chinese male cadavers. They were randomly divided into 5 groups. Cyclical compression was performed for 20,000 cycles with 2 Hz. Load magnitude was determined respectively as 10%, 20% and 30% of the ultimate compressive load. Four cylindrical sections were obtained from each vertebra and the cross-sectional slides were made. The histomorphometry was used to determine microfracture densitiy and distribution. No fracture was detected in the radiographs of groups III, IV and V after fatigue load. Microfracture density in the cyclic compression group increased from 0.46 #/mm2 in Group III to 0.66 #/mm2 (Group IV) and 0.94 #/mm2 (Group V) under different loading levels (). These results provide evidence for the existence of microfractures caused by fatigue loads that are undetectable by X-ray

A monte-carlo floating-point unit for self-validating arithmetic

Monte-Carlo arithmetic is a form of self-validating arith-metic that accounts for the effect of rounding errors. We have implemented a floating point unit that can perform ei-ther IEEE 754 or Monte-Carlo floating point computation, allowing hardware accelerated validation of results during execution. Experiments show that our approach has a mod-est hardware overhead and allows the propagation of round-ing error to be accurately estimated

Effect of different drying methods and solvent ratios on biological activities of Phyllanthus acidus extracts

The main purpose of this study was to evaluate the antioxidant and α-glucosidase inhibitory activities of Phyllanthus acidus. The P. acidus fruits were dried using three different methods, namely oven (OD), air (AD) and freeze (FD) dryings and extracted with ethanol at different ratios (50 and 100%). The proximate analysis and total phenolic content (TPC) as well as free radical scavenging and α-glucosidase inhibitory activities were determined. The proximate analysis of P. acidus fruit indicated that all the dried samples contained potential nutrient contents. The highest TPC value, α-glucosidase inhibitory and antioxidant activities were observed for 50% ethanolic extract from OD method with TPC value of 28.39 mg GAE/g dried extract, IC50 value of 12.394 μg/mL and 64.17% inhibition, respectively. The study revealed that phenolic compounds could be the main contributors to the antioxidant and α-glucosidase inhibitory activities based on the Pearson correlation coefficients with R values of 95.0 and 73.8%, respectively. The study could provide scientific evidence for some folk uses in the treatment of diseases related to the production of reactive oxygen species and oxidative stress

A practical functional observer scheme for interconnected time-delay systems

This paper proposes a partially distributed functional observer scheme for a class of interconnected linear systems with very strong non-instantaneous subsystems interaction and with time delays in the local states and in the transmission of output information from the remote subsystems. A set of easily verifiable existence conditions is established and upon its satisfaction, simple distributed observers are designed using a straightforward design procedure. Simulation results of a numerical example are given to substantiate the feasibility of the approach