Effects of sowing dates on grain yield and yield attributes of sorghum (Sorghum bicolor Moench) cultivar ICSV111 (Kapaala) in northern Ghana

Lack of a suitable sowing date has often been identified as the main constraint to sorghum (Sorghum bicolor Moench) cv. ICSV111 (Kapaala) production in Ghana. Field experiments were, therefore, used on-station at the Manga Agricultural Research Station to evaluate the effects of five sowing dates on yield and yield components of ‘Kapaala\' in northern Ghana. Sowing dates significantly (

Compatibility of Millet and Legume under Relay Cropping Condition

Double-cropping millet and legumes is a popular cropping system in the Upper East region (UER) of Ghana. For improved production efficiency, suitable millet-legume combinations with short life cycles that permit extension of the growing season to facilitate double-cropping need to be explored. The objective of this study was therefore to use performance data to identify millet-legume combinations compatible for relay cropping within the UER. Three early millet cultivars (Bongo Shorthead, Arrow Millet and Bristled Millet) were factorially relayed by three legumes namely cowpea, groundnut and soybean. Bongo Shorthead followed by cowpea in a relay cropping system has the greatest prospect of accounting for superiority in grain and stover/straw yield while Bongo Shorthead followed by groundnut in a relay will provide the least suitable combination for relay cropping within the Upper East Region of Ghana. Keywords: double cropping, millet, legumes, compatible combination, savannah zone

Does psychopathology at admission predict the length of inpatient stay in psychiatry? Implications for financing psychiatric services

Background: The debate on appropriate financing systems in inpatient psychiatry is ongoing. In this context, it is important to control resource use in terms of length of stay (LOS), which is the most costly factor in inpatient care and the one that can be influenced most easily. Previous studies have shown that psychiatric diagnoses provide only limited justification for explaining variation in LOS, and it has been suggested that measures such as psychopathology might be more appropriate to predict resource use. Therefore, we investigated the relationship between LOS and psychopathological syndromes or symptoms at admission as well as other characteristics such as sociodemographic and clinical variables. Methods: We considered routine medical data of patients admitted to the Psychiatric University Hospital Zurich in the years 2008 and 2009. Complete data on psychopathology at hospital admission were available in 3,220 inpatient episodes. A subsample of 2,939 inpatient episodes was considered in final statistical models, including psychopathology as well as complete datasets of further measures (e.g. sociodemographic, clinical, treatment-related and psychosocial variables). We used multivariate linear as well as logistic regression analysis with forward selection procedure to determine the predictors of LOS. Results: All but two syndrome scores (mania, hostility) were positively related to the length of stay. Final statistical models showed that syndromes or symptoms explained about 5% of the variation in length of stay. The inclusion of syndromes or symptoms as well as basic treatment variables and other factors led to an explained variation of up to 25%. Conclusions: Psychopathological syndromes and symptoms at admission and further characteristics only explained a small proportion of the length of inpatient stay. Thus, according to our sample, psychopathology might not be suitable as a primary indicator for estimating LOS and contingent costs. This might be considered in the development of future costing systems in psychiatry

Improving Marketable Quality of Tomato: a Simulation of Shipping Conditions in Ghana

Aim: The study assessed the influence of a sequence of anticipated hazard elements (impact, compression, vibration) and shipment conditions on marketable quality under varying temperatures and ripeness stages. Study Design: The vibration test simulates a truck operating at highway speed and determines the ability of shipping units to withstand vertical and compression forces resulting from stacking during transport. Storage at 30ºC depicted ambient conditions; 15 and 20ºC are optimum temperatures for ripening; and pink and light-red ripeness depict typical harvest maturity in Ghana. Place and Duration of Study: The study was conducted at the Postharvest Science Laboratory of the Horticultural Sciences Department of the University of Florida from September to December 2011. Methodology: Round-type tomato at pink and light-red ripeness were subjected to a vibration test and incubated in ripening chambers set at 15, 20 and 30ºC. Critical data was taken on days to red-ripe, CO2, ethylene production, color, firmness, weight loss, pH, titratable acidity and soluble solids content. Results: Overall, the influence of vibration and ripeness on marketable shelf life was marginal; however temperature significantly (P≤0.05) influenced shelf life. Vibration increased weight loss, respiration and ethylene production, which were plummeted at lower temperature. Days to red-ripe indicated that tomato should preferably be marketed by 2-4, 8-12 and 10-15 days at 30, 20 and 15ºC respectively, at pink to light-red ripeness under current distribution conditions. Best chemical properties were maintained at 15 and 20ºC; vibration and ripeness did not influence chemical properties, but increasing temperature affected all physico-chemical properties. Conclusion: The study concludes that despite the cumbersome shipping conditions, tomatoes could be marketed at premium quality if lower storage temperatures were accessible. These facilities are beyond the purchasing power of small-holder traders, thus the involvement of the State and/or Private Sector to providing these facilities would be beneficial; particularly in urban markets where retail prices will merit such investments

Enhancing farmers’ access to technology for increased rice productivity in Ghana

A two-year emergency rice (Oryza sativa L.) initiative was launched in 2009 in response to the globalrice crises in 2008. The objective of this initiative in Ghana was to increase rice productivity in order toimprove food security. Project activities included planning sessions, demonstrations, training coursesand community seed production. The project made remarkable progress in enhancing access to qualityseed and fertilizer for over 12,600 farmers while expanding knowledge of best-bet productiontechnologies. Farmers produced 28,663 Mt of paddy which was 16,841 Mt above what they normallyproduced without project intervention. Average yield increased by 92% and also 4,093 women farmersconstituting about 32.4% of the total number of participating farmers benefited directly from the project.Seed fairs, rural radios and audio-visual broadcasts on improved rice production technologies wereused to reach non-participating farmers. The combination of methods that stimulated adoption ofimproved rice production technology was effective in achieving both increased paddy yields andhousehold income. We conclude that investment in rice technology transfer and production effortsduring the two-year period was well justified

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development.

Cerebral organoids-3D cultures of human cerebral tissue derived from pluripotent stem cells-have emerged as models of human cortical development. However, the extent to which in vitro organoid systems recapitulate neural progenitor cell proliferation and neuronal differentiation programs observed in vivo remains unclear. Here we use single-cell RNA sequencing (scRNA-seq) to dissect and compare cell composition and progenitor-to-neuron lineage relationships in human cerebral organoids and fetal neocortex. Covariation network analysis using the fetal neocortex data reveals known and previously unidentified interactions among genes central to neural progenitor proliferation and neuronal differentiation. In the organoid, we detect diverse progenitors and differentiated cell types of neuronal and mesenchymal lineages and identify cells that derived from regions resembling the fetal neocortex. We find that these organoid cortical cells use gene expression programs remarkably similar to those of the fetal tissue to organize into cerebral cortex-like regions. Our comparison of in vivo and in vitro cortical single-cell transcriptomes illuminates the genetic features underlying human cortical development that can be studied in organoid cultures

Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes

We generated induced excitatory neurons (iNeurons, iNs) from chimpanzee, bonobo, and human stem cells by expressing the transcription factor neurogenin-2 (NGN2). Single-cell RNA sequencing showed that genes involved in dendrite and synapse development are expressed earlier during iNs maturation in the chimpanzee and bonobo than the human cells. In accordance, during the first 2 weeks of differentiation, chimpanzee and bonobo iNs showed repetitive action potentials and more spontaneous excitatory activity than human iNs, and extended neurites of higher total length. However, the axons of human iNs were slightly longer at 5 weeks of differentiation. The timing of the establishment of neuronal polarity did not differ between the species. Chimpanzee, bonobo, and human neurites eventually reached the same level of structural complexity. Thus, human iNs develop slower than chimpanzee and bonobo iNs, and this difference in timing likely depends on functions downstream of NGN2

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

Cerebral organoids—3D cultures of human cerebral tissue derived from pluripotent stem cells—have emerged as models of human cortical development. However, the extent to which in vitro organoid systems recapitulate neural progenitor cell proliferation and neuronal differentiation programs observed in vivo remains unclear. Here we use single-cell RNA sequencing (scRNA-seq) to dissect and compare cell composition and progenitor-to-neuron lineage relationships in human cerebral organoids and fetal neocortex. Covariation network analysis using the fetal neocortex data reveals known and previously unidentified interactions among genes central to neural progenitor proliferation and neuronal differentiation. In the organoid, we detect diverse progenitors and differentiated cell types of neuronal and mesenchymal lineages and identify cells that derived from regions resembling the fetal neocortex. We find that these organoid cortical cells use gene expression programs remarkably similar to those of the fetal tissue to organize into cerebral cortex-like regions. Our comparison of in vivo and in vitro cortical single-cell transcriptomes illuminates the genetic features underlying human cortical development that can be studied in organoid cultures

Partnership for improved access to agro-inputs and technology: Some experiences from the emergency rice initiative project in Ghana

A two-year emergency rice (Oryza sativa L.) initiative project was launched in 2009 in response to the global rice crisis in 2008. The objective of this initiative in Ghana was to increase rice productivity in order to improve food security. Project activities included seed fairs, dissemination of information on improved production technologies using videos and rural radios, training of agro-input dealers,extension officers and farmers as well as promotion of best-bet practices through field demonstrations.The project made progress in strengthening the ability of agro-input dealers to create business linkages with input suppliers and extend their retail networks to rice farmers. Overall, 34 agro-input dealers were trained, in collaboration with the Ghana Agro-dealer Development project, on agro-input business management, product knowledge and rice production. Thirteen agro-input dealers were assisted to access credit for business development. Better financed, trained agro-dealers were then able to provide over 12,600 rice farmers with improved seed, mineral fertilizers, technical advice on agro-input use and the promotion of improved agronomic practices through field demonstrations. Some agro-input dealers even provided free inputs for the conduct of demonstrations on new products and good agronomic practices. On average, fertilizer application in demonstration trials increased paddy yields by 68 to 80%over the farmer practice of no fertilizer application. For the participating farmers, there were significant increases in rice paddy yields, reductions in the cost of operations and improvements in the contribution of rice to household incomes. The results suggest that a holistic and multi-stakeholder partnership is an efficient way to improve the access by small-holder resource-poor farmers to agro-inputs and technology and also an effective way to grow the rural agro-input marke