SUSY-QCD corrections in the squark-gluino sector

A status report is given of the calculations of next-to-leading-order ($N=1$) supersymmetric QCD corrections to the production of squarks and gluinos in $p\bar{p}/pp$ collisions. The implementation of these SUSY-QCD corrections leads to more stable theoretical predictions and to a substantial increase of the production cross-sections. In addition we give a discussion of the use of the $\overline{MS}$ scheme for renormalizing the coupling constants in the QCD sector of ($N=1$) supersymmetric theories.Comment: 6 two-column pages, tar'ed gzip'ed uuencoded files, LaTeX, 7 Encapsulated Postscript figures, uses epsfig and espcrc2. To appear in the proceedings of the 1996 Zeuthen Workshop on Elementary Particle Theory: "QCD and QED in Higher Orders", J.Bl\"umlein, F.Jegerlehner, and T.Riemann eds. Complete postscript file available at http://rulgm4.LeidenUniv.nl/preprints.htm

Stop decays in SUSY-QCD

The partial widths are determined for stop decays to top quarks and gluinos, and gluino decays to stop particles and top quarks (depending on the masses of the particles involved). The widths are calculated including one-loop SUSY-QCD corrections. The radiative corrections for these strong-interaction decays are compared with the SUSY-QCD corrections for electroweak stop decays to quarks and neutralinos/charginos and top-quark decays to stops and neutralinos.Comment: 20 pages, LaTeX, 8 figures (uses epsfig). Complete postscript file available at http://rulgm4.LeidenUniv.nl/preprints.htm

Gluon Radiation Off Scalar Stop Particles

We present the distributions for gluon radiation off stop-antistop particles produced in $e^+e^-$ annihilation: $e^+e^- \to \tilde t \bar{\tilde t} g$. For high energies the splitting functions of the fragmentation processes $\tilde t \to \tilde t g$ and $g \to \tilde t \bar{\tilde t}$ are derived; they are universal and apply also to high-energy stop particles produced at hadron colliders.Comment: 9 pages, 2 figures as uuencoded ps files, Latex, uses epsfig, complete postscript version at ftp://x4u2.desy.de/pub/preprints/desy/1994/desy94-235.p

SUSY-QCD Decays of Squarks and Gluinos

The partial widths are determined for squark decays to gluinos and quarks, and gluino decays to squarks and quarks, respectively. The widths are calculated including one-loop SUSY-QCD corrections. The corrections amount to $+$30\% to $+$50\% for squark decays and $-$10\% to $+$10\% for gluino decays. We have derived the results in the \DR ~and \MS ~renormalization schemes, and we have demonstrated explicitly that the one-loop effective $qqg$ and q\sq\gl couplings are equal in the limit of exact supersymmetry.Comment: 11 pages, Latex2e, 2 figures (uses epsfig). Complete postscript file available at http://www.desy.de/pub/preprints/desy/1996/desy96-022.p

Gluino-Pair Production at the Tevatron

The next-to-leading order QCD corrections to the production of gluino pairs at the Tevatron are presented in this paper. Similar to the production of squark-antisquark pairs, the dependence of the cross section on the renormalization/factorization scale is reduced considerably by including the higher-order corrections. The cross section increases with respect to the lowest-order calculation which, in previous experimental analyses, had been evaluated at the scale of the invariant energy of the partonic subprocesses.Comment: 10 pages, Latex, 4 eps-files in uu-format (uses epsfig), the complete postscript file is available via anonymous ftp at ftp://x4u2.desy.de/pub/preprints/desy/1995/desy95-104.p

Mechanosensing is critical for axon growth in the developing brain.

During nervous system development, neurons extend axons along well-defined pathways. The current understanding of axon pathfinding is based mainly on chemical signaling. However, growing neurons interact not only chemically but also mechanically with their environment. Here we identify mechanical signals as important regulators of axon pathfinding. In vitro, substrate stiffness determined growth patterns of Xenopus retinal ganglion cell axons. In vivo atomic force microscopy revealed a noticeable pattern of stiffness gradients in the embryonic brain. Retinal ganglion cell axons grew toward softer tissue, which was reproduced in vitro in the absence of chemical gradients. To test the importance of mechanical signals for axon growth in vivo, we altered brain stiffness, blocked mechanotransduction pharmacologically and knocked down the mechanosensitive ion channel piezo1. All treatments resulted in aberrant axonal growth and pathfinding errors, suggesting that local tissue stiffness, read out by mechanosensitive ion channels, is critically involved in instructing neuronal growth in vivo.This work was supported by the German National Academic Foundation (scholarship to D.E.K.), Wellcome Trust and Cambridge Trusts (scholarships to A.J.T.), Winston Churchill Foundation of the United States (scholarship to S.K.F.), Herchel Smith Foundation (Research Studentship to S.K.F.), CNPq 307333/2013-2 (L.d.F.C.), NAP-PRP-USP and FAPESP 11/50761-2 (L.d.F.C.), UK EPSRC BT grant (J.G.), Wellcome Trust WT085314 and the European Research Council 322817 grants (C.E.H.); an Alexander von Humboldt Foundation Feodor Lynen Fellowship (K.F.), UK BBSRC grant BB/M021394/1 (K.F.), the Human Frontier Science Program Young Investigator Grant RGY0074/2013 (K.F.), the UK Medical Research Council Career Development Award G1100312/1 (K.F.) and the Eunice Kennedy Shriver National Institute Of Child Health & Human Development of the National Institutes of Health under Award Number R21HD080585 (K.F.).This is the author accepted manuscript. The final version is available from Nature Publishing Group via https://doi.org/10.1038/nn.439

Intercellular Adhesion Molecule-5 Induces Dendritic Outgrowth by Homophilic Adhesion

Intercellular adhesion molecule-5 (ICAM-5) is a dendritically polarized membrane glycoprotein in telencephalic neurons, which shows heterophilic binding to leukocyte b2-integrins. Here, we show that the human ICAM-5 protein interacts in a homophilic manner through the binding of the immunoglobulin domain 1 to domains 4–5. Surface coated ICAM-5-Fc promoted dendritic outgrowth and arborization of ICAM- 5–expressing hippocampal neurons. During dendritogenesis in developing rat brain, ICAM-5 was in monomer form, whereas in mature neurons it migrated as a high molecular weight complex. The findings indicate that its homophilic binding activity was regulated by nonmonomer/monomer transition. Thus, ICAM-5 displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes