Nanoscale roughness and morphology affect the IsoElectric Point of titania surfaces

We report on the systematic investigation of the role of surface nanoscale roughness and morphology on the charging behaviour of nanostructured titania (TiO2) surfaces in aqueous solutions. IsoElectric Points (IEPs) of surfaces have been characterized by direct measurement of the electrostatic double layer interactions between titania surfaces and the micrometer-sized spherical silica probe of an atomic force microscope in NaCl aqueous electrolyte. The use of a colloidal probe provides well-defined interaction geometry and allows effectively probing the overall effect of nanoscale morphology. By using supersonic cluster beam deposition to fabricate nanostructured titania films, we achieved a quantitative control over the surface morphological parameters. We performed a systematical exploration of the electrical double layer properties in different interaction regimes characterized by different ratios of characteristic nanometric lengths of the system: the surface rms roughness Rq, the correlation length {\xi} and the Debye length {\lambda}D. We observed a remarkable reduction by several pH units of IEP on rough nanostructured surfaces, with respect to flat crystalline rutile TiO2. In order to explain the observed behavior of IEP, we consider the roughness-induced self-overlap of the electrical double layers as a potential source of deviation from the trend expected for flat surfaces.Comment: 63 pages, including 7 figures and Supporting Informatio

ROLE OF PRAKRITI IN SELECTION OF COSMETIC PRODUCTS

Ayurveda is an ancient science of life. It attributes primary aim towards prevention and health maintenance. Health promotion depends on toxin (Ama) free systems, restoration of cellular nutrition and maintenance of balance of Doshas. The major preventive approaches for maintaining and improving the quality of life includes individualized specific daily regimen (Dinacharya), seasonal regimen (Rutucharya), behavioral and ethical consideration (Sadvrittas). Healthy lifestyle is emphasized as the determinant of longevity of life which depends on the Prakriti (bio-identity i.e. body - mind constitution) of an individual. Prakriti is an important concept of Ayurveda. Prakriti is a combination of Physical, Physiological and Psychological characteristics of an individual. In Ayurveda concept of personality and beauty is expressed in terms of Prakriti, Sara and Anguli Praman etc. Variation in skin characteristics are also mentioned in Ayurveda as per dominant Deha Prakriti. Day by day cosmetic field is gaining wide importance along with its increased demand. On other hand skin problems are also increasing which causes damage to skin due to overuse or misuse of cosmetics. It requires knowledge of cosmetic science along with Prakriti while choosing any cosmetics otherwise random use of any cosmetics may cause adverse effect on skin. Awareness about Prakriti gives guideline by suggesting Aahar vihar and lifestyle modification according to Prakriti so that one can maintain skin health. The main aim of this study is to provide awareness to healthy individuals about role of Prakriti while selecting skin care cosmetics products. For this study literature collection is done from various Samhita Granths, cosmetic books, thesis research work of related topics, and current research papers

EVALUATION OF PRESCRIBING PATTERN OF FIXED DOSE COMBINATIONS OF ANTIHYPERTENSIVES AND ANTIDIABETIC AGENTS

  Objective: The objective of this research was to evaluate prescribing pattern of fixed dose combinations (FDCs) of antihypertensives and antidiabetic agents among patients of private hospitals.Methods: An observational study was carried out in the outpatient department of two hospitals. Data of patients being diagnosed with the symptoms of hypertension and diabetes were enrolled which mainly included information related to prescribe FDCs, i.e., antihypertensives and antidiabetics, respectively. Descriptive analysis of collected information was done which involved representation of demographical data, number of comorbidities, number of FDCs prescribed, and type of FDCs consequently.Results: Combination drug therapy was prescribed in maximum patients, which was enumerated as 93% among hypertensive patients and about 91% in diabetics. Average age of patients suffering more from hypertension was 64.5±18 years and that in case of diabetes sufferers was 54.5±18 years. The most frequent combination prescribed in hypertensive patients was of angiotensin receptor blocker (ARB) and calcium channel blocker (CCB) which were about 53%, and in diabetic patients, it was of biguanides and sulfonylureas about 63%. Comorbidity too was notified, and its estimation was 61% in hypertensive patients and 72% in diabetic patients, respectively.Conclusion: The study here demonstrates that the most often prescribed antihypertensive combination is of ARB and CCB, and subsequently for diabetes, the oral hypoglycemic combination is of biguanides and sulfonylureas. Most of FDCs contained medications of these two classes. Positive results were also observed in levels of blood pressure and glucose within the normal range

Računanje vrpčaste strukture nelokalnim pseudopotencijalima

Energy bands of Rb and Cs have been calculated for the first time using average or effective pseudopotentials obtained from non-local ones. It is shown that the results so obtained compare well to those obtained with full non-local calculations.Načinili smo prve račune energijskih vrpci Rb i Cs primjenom prosječnog ili efektivnog pseudopotencijala koji smo izveli iz nelokalnih pseudopotencijala. Pokazuje se dobra suglasnost ishoda tih računa i računa primjenom potpunih nelokalnih pseudopotencijala

Obesity and Atrial Fibrillation: Epidemiology, Pathophysiology and Novel Therapeutic Opportunities

Obesity is already a major global public health issue, implicated in a vast array of conditions affecting multiple body systems. It is now also firmly established as an independent risk factor in the incidence and progression of AF. The rapidly rising morbidity, mortality and healthcare costs associated with AF despite implementation of the three pillars of AF management - anticoagulation, rate control and rhythm control - suggest other strategies need to be considered. Compelling data has unveiled novel insights into adipose tissue biology and its effect on arrhythmogenesis while secondary prevention strategies targeting obesity as part of a comprehensive risk factor management programme have been demonstrated to be highly effective. Here, the authors review the epidemiological basis of the obesity-AF relationship, consider its underlying pathophysiology and discuss new therapeutic opportunities on the horizon

Theoretical study of pressure dependence of superconducting state parameters of some metals using pseudopotential approach

In the present theoretical study, we have calculated superconducting state parameters (SSPs) viz; electron-phonon coupling strength (λ), Coulomb pseudopotential (µ*), critical temperature (Tc), effective interaction strength (N0V) and isotopic effect parameter ( α) of some polyvalent metals (Pb, Ga, In, Sn and Tl) using well-established structured local pseudopotential due to Fiolhais et al. (1995). The pseudopotential with its individual set of parameters has been found to be good in predicting transition temperature Tc for all the metals. Looking to such success, we have extended the present model for the theoretical study of pressure dependence of transition temperature Tc using Debye- Gruneisen model. Our predicted critical volumes using different approaches are well agreed with each other and also with other reported findings. Thus, the present model is consistent and better than nonlocal norm conserving pseudopotentials because it is found to be transferable without any kind of adjustment of its parameters along with its simplicity and predictivity

An overview of the predictors of symptomatic urinary tract infection among nursing students

Background: Urinary tract infection (UTI) is the most common infection experienced by humans after respiratory and gastro‑intestinal infections, and also the most common cause of nosocomial infections for patients admitted to hospitals indeed UTIs are the most frequent bacterial infection in women. Aim: The aim was to determine the prevalence of UTI and to identify factors associated with an increased risk of UTI among nursing students. Subjects and Methods: The cross‑sectional study involved 177 unmarried nursing students aged 18–30 years studying in the SRMSIMS, Nursing College Bareilly. A structured questionnaire was used, and study subjects were asked regarding the symptoms of UTI in the previous 3 months. Chi‑square test and Univariate Logistic Regression was used to analyze the data. Results: The overall prevalence of UTI was found to be 19.8% (35/177). Rural background, inadequate water intake, and unsatisfactory toilet habits were found to be strong predictors of UTI. Conclusions: There is an urgent need to sensitize the nursing students regarding the growing need of the issue so that they themselves become aware in addition to raising the awareness of other high‑risk groups.Keywords: Nursing students, Prevalence, Urinary tract infectio