80 research outputs found

    A Novel CPW Fed MIMO Antenna for UWB Applications

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    This paper presents two planar antennas designed from a compact novel CPW fed UWB antenna. The first antenna is single UWB antenna. The single UWB antenna covers the entire UWB frequency band. Single antenna operates in 2.8 GHz to 12.6 GHz. The second antenna is MIMO antenna which is made with orthogonal placement of two UWB antennas and MIMO antennas covers the entire UWB frequency band. The MIMO antenna with orthogonal placement of antennas operates in 2.9 GHz to 12.7 GHz band. The designed single antenna has dimensions of 27 X 34 X 1.6 mm3 and MIMO antennas have volume of 61 X 34 X 1.6 mm3 for orthogonal placement. Antenna has satisfactory performance in terms gain, radiation pattern, return loss, voltage standing wave ratio, envelope correlation coefficient and diversity gain for UWB MIMO application

    Role of spatial tools in public health policymaking of Bangladesh: opportunities and challenges

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    In spite of the increasing efforts to gather spatial data in developing countries, the use of maps is mostly for visualization of health indicators rather than informed decision-making. Various spatial tools can aid policymakers to allocate resources effectively, predict patterns in communicable or infectious diseases, and provide insights into geographical factors which are associated with utilization or adequacy of health services. In Bangladesh, the launch of District Health Information System 2, along with recent efforts to gather spatial data of facilities location, provides an interesting opportunity to study the current landscape and the potential barriers in advancing the use of spatial tools for informed decision making. This study assessed the current level of map usage and spatial tools for health sector planning in Bangladesh, focusing on investigating why map usage and spatial tools remained at a basic level for the purpose of health policy. The study design involved in-depth interviews, followed by an expert survey (n = 39) obtained through snowball sampling. Our survey revealed that assessing areas with shortage of community health workers emerged as the top most for basic map usage or primarily for visualization purpose, while planning for emergency and obstetric care services, and disease mapping was the most frequent category for intermediate and advanced map usage, respectively. Furthermore, we found lack of inter-institutional collaboration, lack of continuous availability of trained personnel, and lack of awareness on the use of geographic information system (GIS) as a decision-making tool as three most critical barriers in the current landscape. Our findings highlight the barriers in increasing the adoption of spatial tools for health policymaking and planning in Bangladesh

    Sattvavajaya Chikitsa (psychotherapy) as a preventive aspect in Akalaja Jara (premature ageing)

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    The present condition of human health around the globe is far from satisfaction. Man is suffering from the diseases which are caused due to stress either mental or physical and premature ageing (Akalaja Jara) is one of them. There are many theory related to ageing among all of them Free Radical Theory is most acceptable, which answers most of the questions related with Psychological as well as Physical changes during ageing. Stress can be considered as a major factor for Akalaja Jara. Sattvavajaya Chikitsa is a specialized type of treatment influencing the psychological aspect of body. It can be applied in the form of Yogic practices and other mind control techniques. As mind and body are interrelated to each other, these techniques also affect physical health. It is the unique concept of Ayurveda which may be effective in improving quality of life. That is why to deal with stress and to prevent Akalaja Jara, Sattvavajaya (control of mind from unwholesome objects) could be a better approach

    Outdoor Performance and Stability Assessment of Dye-Sensitized Solar Cells (DSSCs)

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    In this era the requirement for energy is enhancing, therefore, many energy resources are developed among them the emerging third-generation dye-sensitized solar cell is one of the environment-friendly solar cell-based technology. Generally, dye-sensitized solar cells consist of a nanomaterial-based photoanode, dye molecules as an absorber, electrolyte, and counter electrode. In the case of indoor application, this solar cell works easily so this is the characteristics of a dye-sensitized solar cell. Moreover, the outdoor performance of DSSC degrades on exposure to sunlight. Exposure to sunlight increases the temperature of the internal component of DSSC and consequently degradation in device performance. Long-term stability is obtained by the choice of such material where degradation takes place slowly and plastic covers are also coated over DSSC to prevent degradation. The solar response of DSSC towards dye was also mentioned, the higher the percentage of EQE higher the efficiency of the device. In this chapter, the authors discuss the introduction of a solar cell, the working principle of DSSC, and the available research background for outdoor performance and long-term stability with a solar response of device i.e. EQE or IPCE

    Making of a unique birth control vaccine against hCG with additional potential of therapy of advanced stage cancers and prevention of obesity and insulin resistance

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    Reviewed is the work which led to the development of a unique vaccine that prevents pregnancy in sexually active women without impairment of ovulation and block of their making normally their sex steroid hormones. Being given that hCG is not expressed by non-pregnant females, immunization with the vaccine is devoid of any crossreaction with any tissue of the body. It is totally reversible and women regained fertility on decline of antibodies. A recombinant vaccine has been developed which is highly immunogenic in mice. It is undergoing extensive toxicology under GLP conditions in rodents and a primate species, the marmosets, before resumption of clinical trials. Ectopic expression of hCG or its subunits takes place in a variety of cancers, particularly at advanced stage with adverse survival and poor prognosis. Anti-hCG antibodies exercise therapeutic action against such cancers as indicated by in vitro culture and in vivo studies in nude mice. Transgenic hCG β mice put on weight and manifest insulin resistance. Immunization of these mice with the recombinant hCG β-LTB vaccine prevents obesity and insulin resistance.Fil: Talwar, G. P.. Talwar Research Foundation; IndiaFil: Rulli, Susana Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); ArgentinaFil: Vyas, Hemant. Harvard Medical School; Estados UnidosFil: Purswani, Shilpi. Talwar Research Foundation; IndiaFil: Kabeer, Rafi Shiraz. Talwar Research Foundation; IndiaFil: Chopra, Prem. Sir Ganga Ram Hospital; IndiaFil: Singh, Priyanka . Talwar Research Foundation; IndiaFil: Atrey, Nishu. Talwar Research Foundation; IndiaFil: Nand, Kripa. Talwar Research Foundation; IndiaFil: Gupta, Jagdish C.. Talwar Research Foundation; Indi

    Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

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    Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
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