9,549 research outputs found
Data Preservation in High Energy Physics - why, how and when?
Long-term preservation of data and software of large experiments and
detectors in high energy physics is of utmost importance to secure the heritage
of (mostly unique) data and to allow advanced physics (re-)analyses at later
times. Summarising the work of an international study group, motivation, use
cases and technical details are given for an organised effort to secure and
enable future use of past, present and future experimental data. As a practical
use case and motivation, the revival of JADE data and the corresponding latest
results on measuring in NNLO QCD are reviewed.Comment: 5 pages, 3 figures; presentation given at the QCD10, Montpellier,
France, June 201
Probing Plasmodium falciparum sexual commitment at the single-cell level
Background: Malaria parasites go through major transitions during their complex life cycle, yet the underlying differentiation pathways remain obscure. Here we apply single cell transcriptomics to unravel the program inducing sexual differentiation in Plasmodium falciparum. Parasites have to make this essential life-cycle decision in preparation for human-to-mosquito transmission. Methods: By combining transcriptional profiling with quantitative imaging and genetics, we defined a transcriptional signature in sexually committed cells. Results: We found this transcriptional signature to be distinct from general changes in parasite metabolism that can be observed in response to commitment-inducing conditions. Conclusions: This proof-of-concept study provides a template to capture transcriptional diversity in parasite populations containing complex mixtures of different life-cycle stages and developmental programs, with important implications for our understanding of parasite biology and the ongoing malaria elimination campaign
Increasing the psychosocial focus in child developmental assessments : A qualitative study
Acknowledgements Authors are grateful for the contribution of knowledge from the clinicians participating in the interviews. Furthermore, we gratefully acknowledge the work of all our colleagues in the Family Wellbeing team. A special acknowledgement is due to Professor Jakob Kragstrup who supervised the first author and reviewed the work. We thank Dr. Anette Graungaard for reviewing the article and designing the child records together with Dr. Kirsten Lykke. The parent-child interaction assessment tool was based on the CARO assessment designed by Dr Christine Puckering. Funding The finances for the recruitment of clinics, data collection and part of the salaries are covered by funding from TrygFonden to the Family Wellbeing trial. Educational expenses and remaining part of the salaries are covered by funding from The Quality and Education Committee (KEU), Capital Region of Denmark.Peer reviewedPublisher PD
Multifractal characterisation of length sequences of coding and noncoding segments in a complete genome
The coding and noncoding length sequences constructed from a complete genome
are characterised by multifractal analysis. The dimension spectrum and
its derivative, the 'analogous' specific heat , are calculated for the
coding and noncoding length sequences of bacteria, where is the moment
order of the partition sum of the sequences. From the shape of the
and curves, it is seen that there exists a clear difference between the
coding/noncoding length sequences of all organisms considered and a completely
random sequence. The complexity of noncoding length sequences is higher than
that of coding length sequences for bacteria. Almost all curves for
coding length sequences are flat, so their multifractality is small whereas
almost all curves for noncoding length sequences are multifractal-like.
We propose to characterise the bacteria according to the types of the
curves of their noncoding length sequences.Comment: 15 pages with 5 figures, Latex, Accepted for publication in Physica
Avaliação de genótipos de trigo e de outros cereais de inverno ao crestamento, em solo com e sem aplicação de calcårio.
bitstream/CNPT-2010/40694/1/p-do76.pd
The type Ib supernova 2010O: an explosion in a Wolf-Rayet X-ray binary?
The type Ib supernova 2010O was recently discovered in the interacting
starburst galaxy Arp 299. We present an analysis of two archival Chandra X-ray
observations of Arp 299, taken before the explosion and show that there is a
transient X-ray source at a position consistent with the supernova. Due to the
diffuse emission, the background is difficult to estimate. We estimate the flux
of the transient from the difference of the two X-ray images and conclude that
the transient can be described by a 0.225 keV black body with a luminosity of
2.5+/-0.7 10^{39} erg/s for a distance of 41 Mpc. These properties put the
transient in between the Galactic black hole binary XTE J1550-564 and the
ultra-luminous X-ray binaries NGC 1313 X-1 and X-2. The high level of X-ray
variability associated with the active starburst makes it impossible to rule
out a chance alignment. If the source is associated with the supernova, it
suggests SN2010O is the explosion of the second star in a Wolf-Rayet X-ray
binary, such as Cyg X-3, IC 10 X-1 and NGC 300 X-1.Comment: Accepted version. To appear in MNRAS
Language Time Series Analysis
We use the Detrended Fluctuation Analysis (DFA) and the Grassberger-Proccacia
analysis (GP) methods in order to study language characteristics. Despite that
we construct our signals using only word lengths or word frequencies, excluding
in this way huge amount of information from language, the application of
Grassberger- Proccacia (GP) analysis indicates that linguistic signals may be
considered as the manifestation of a complex system of high dimensionality,
different from random signals or systems of low dimensionality such as the
earth climate. The DFA method is additionally able to distinguish a natural
language signal from a computer code signal. This last result may be useful in
the field of cryptography.Comment: 21 pages, 5 figures, accepted in Physica
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