Modelling Social Structures and Hierarchies in Language Evolution

Language evolution might have preferred certain prior social configurations over others. Experiments conducted with models of different social structures (varying subgroup interactions and the role of a dominant interlocutor) suggest that having isolated agent groups rather than an interconnected agent is more advantageous for the emergence of a social communication system. Distinctive groups that are closely connected by communication yield systems less like natural language than fully isolated groups inhabiting the same world. Furthermore, the addition of a dominant male who is asymmetrically favoured as a hearer, and equally likely to be a speaker has no positive influence on the disjoint groups.Comment: 14 pages, 3 figures, 1 table. In proceedings of AI-2010, The Thirtieth SGAI International Conference on Innovative Techniques and Applications of Artificial Intelligence, Cambridge, England, UK, 14-16 December 201

Quantum state engineering via unitary transformations

We construct a Hamiltonian for the generation of arbitrary pure states of the quantized electromagnetic field. The proposition is based upon the fact that a unitary transformation for the generation of number states has been already found. The general unitary transformation here obtained, would allow the use of nonlinear interactions for the production of pure states. We discuss the applicability of this method by giving examples of generation of simple superposition states. We also compare our Hamiltonian with the one resulting from the interaction of trapped ions with two laser fields.Comment: 5 pages in RevTeX, no figures, accepted for publication in Phys. Rev.

Degeneracies when T=0 Two Body Matrix Elements are Set Equal to Zero and Regge's 6j Symmetry Relations

The effects of setting all T=0 two body interaction matrix elements equal to a constant (or zero) in shell model calculations (designated as $=0$) are investigated. Despite the apparent severity of such a procedure, one gets fairly reasonable spectra. We find that using $=0$ in single j shell calculations degeneracies appear e.g. the $I={1/2} ^{-}$ and ${13/2}^{-}$ states in $^{43}$Sc are at the same excitation energies; likewise the I=$3_{2}^{+}$,$7_{2}^{+}$,9$^{+}_{1}$ and 10$^{+}_{1}$ states in $^{44}$Ti. The above degeneracies involve the vanishing of certain 6j and 9j symbols. The symmetry relations of Regge are used to explain why these vanishings are not accidental. Thus for these states the actual deviation from degeneracy are good indicators of the effects of the T=0 matrix elements. A further indicator of the effects of the T=0 interaction in an even - even nucleus is to compare the energies of states with odd angular momentum with those that are even

Integrated cardiopulmonary MRI assessment of pulmonary hypertension

Pulmonary hypertension (PH) is a heterogeneous condition that can affect the lung parenchyma, pulmonary vasculature, and cardiac chambers. Accurate diagnosis often requires multiple complex assessments of the cardiac and pulmonary systems. MRI is able to comprehensively assess cardiac structure and function, as well as lung parenchymal, pulmonary vascular, and functional lung changes. Therefore, MRI has the potential to provide an integrated functional and structural assessment of the cardiopulmonary system in a single exam. Cardiac MRI is used in the assessment of PH in most large PH centers, whereas lung MRI is an emerging technique in patients with PH. This article reviews the current literature on cardiopulmonary MRI in PH, including cine MRI, black-blood imaging, late gadolinium enhancement, T1 mapping, myocardial strain analysis, contrast-enhanced perfusion imaging and contrast-enhanced MR angiography, and hyperpolarized gas functional lung imaging. This article also highlights recent developments in this field and areas of interest for future research including cardiac MRI-based diagnostic models, machine learning in cardiac MRI, oxygen-enhanced 1H imaging, contrast-free 1H perfusion and ventilation imaging, contrast-free angiography and UTE imaging

Life expectancy in older adults with advanced cancer: Evaluation of a geriatric assessment-based prognostic model

Objectives: Oncologists estimate patients' prognosis to guide care. Evidence suggests oncologists tend to overestimate life expectancy, which can lead to care with questionable benefits. Information obtained from geriatric assessment may improve prognostication for older adults. In this study, we created a geriatric assessment-based prognostic model for older adults with advanced cancer and compared its performance to alternative models. Materials and methods: We conducted a secondary analysis of a trial (URCC 13070; PI: Mohile) capturing geriatric assessment and vital status up to one year for adults age ≥ 70 years with advanced cancer. Oncologists estimated life expectancy as 0–6 months, 7–12 months, and > 1 year. Three statistical models were developed: (1) a model including age, sex, cancer type, and stage (basic model), (2) basic model + Karnofsky Performance Status (≤50, 60–70, and 80+) (KPS model), and (3) basic model +16 binary indicators of geriatric assessment impairments (GA model). Cox regression was used to model one-year survival; c-indices and time-dependent c-statistics assessed model discrimination and stratified survival curves assessed model calibration. Results: We included 484 participants; mean age was 75; 48% had gastrointestinal or lung cancer. Overall, 43% of patients died within one year. Oncologists classified prognosis accurately for 55% of patients, overestimated for 35%, and underestimated for 10%. C-indices were 0.61 (basic model), 0.62 (KPS model), and 0.63 (GA model). The GA model was well-calibrated. Conclusions: The GA model showed moderate discrimination for survival, similar to alternative models, but calibration was improved. Further research is needed to optimize geriatric assessment-based prognostic models for use in older adults with advanced cancer

VERTICO. IV. Environmental effects on the gas distribution and star formation efficiency of Virgo cluster spirals

GalaxiesInterstellar matter and star formatio

VERTICO: The Virgo Environment Traced in CO Survey

Galaxie

Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics

Next-generation sequencing (NGS) panel analysis on DNA from formalin-fixed paraffin-embedded (FFPE) tissue is increasingly used to also identify actionable copy number gains (gene amplifications) in addition to sequence variants. While guidelines for the reporting of sequence variants are available, guidance with respect to reporting copy number gains from gene-panel NGS data is limited. Here, we report on Dutch consensus recommendations obtained in the context of the national Predictive Analysis for THerapy (PATH) project, which aims to optimize and harmonize routine diagnostics in molecular pathology. We briefly d