290 research outputs found
Tricholosporum caraibicum (Basidiomycota, Tricholomataceae), a new species from the Dominican Republic
Maternal anxiety, depression and sleep disorders before and during pregnancy, and preschool ADHD symptoms in the NINFEA birth cohort study
In Vitro Cytotoxic Effect of Aqueous Extracts from Leaves and Rhizomes of the Seagrass Posidonia oceanica (L.) Delile on HepG2 Liver Cancer Cells: Focus on Autophagy and Apoptosis
Aqueous extracts from Posidonia oceanica’s green and brown (beached) leaves and rhizomes
were prepared, submitted to phenolic compound and proteomic analysis, and examined for their
potential cytotoxic effect on HepG2 liver cancer cells in culture. The chosen endpoints related to
survival and death were cell viability and locomotory behavior, cell-cycle analysis, apoptosis and
autophagy, mitochondrial membrane polarization, and cell redox state. Here, we show that 24 h
exposure to both green-leaf- and rhizome-derived extracts decreased tumor cell number in a dose–
response manner, with a mean half maximal inhibitory concentration (IC50) estimated at 83 and
11.5 µg of dry extract/mL, respectively. Exposure to the IC50 of the extracts appeared to inhibit cell
motility and long-term cell replicating capacity, with a more pronounced effect exerted by the rhizomederived preparation. The underlying death-promoting mechanisms identified involved the downregulation of autophagy, the onset of apoptosis, the decrease in the generation of reactive oxygen
species, and the dissipation of mitochondrial transmembrane potential, although, at the molecular
level, the two extracts appeared to elicit partially differentiating effects, conceivably due to their
diverse composition. In conclusion, P. oceanica extracts merit further investigation to develop novel
promising prevention and/or treatment agents, as well as beneficial supplements for the formulation
of functional foods and food-packaging material with antioxidant and anticancer propertie
Trace elements and stable isotopes in penguin chicks and eggs: A baseline for monitoring the Ross Sea MPA and trophic transfer studies
Multi-tissue trace elements (TEs), C, N concentrations and stable isotopes (δ13C, δ15N) of chick carcasses and eggs of Adélie and Emperor penguins were studied to i) provide reference data before the recent institution of the Ross Sea Marine Protected Area (Antarctica), and ii) provide conversion factors that allow estimating C, N, δ13C and δ15N in edible tissues from non-edible ones, thus improving the use of stable isotopes in contamination and trophic transfer studies. Higher concentrations of As, Cd, Cr, Cu, Hg, Mn and Pb were found in chick carcasses than in eggs, suggesting increasing contamination in recent decades and high toxicity risks for penguin consumers. Isotopic conversion factors highlighted small differences among body tissues and conspecifics. These values suggest that chick carcasses are reliable indicators of the energy pathways underlying the two penguin species, their trophic position in the food web and their exposure to TEs
Notulae to the Italian flora of algae, bryophytes, fungi and lichens: 5
In this contribution, new data concerning bryophytes, fungi, and lichens of the Italian flora are presented. It includes new records and confirmations for the bryophyte genera Diplophyllum and Ptychostomum, the fungal genera Arrhenia, Gymnosporangium, and Sporidesmium and the lichen genera Arthonia, Coenogonium, Flavoplaca, Gyalolechia, Parmotrema, Peltigera, Pterygiopsis, Squamarina, Tornabea, and Waynea
Notulae to the Italian flora of algae, bryophytes, fungi and lichens: 7
In this contribution, new data concerning algae, bryophytes, fungi, and lichens of the Italian flora are presented. It includes new records and confirmations for the algae genus Chara, the bryophyte genera Cephalozia, Conardia, Conocephalum, Didymodon, Sphagnum, Tetraplodon, and Tortula, the fungal genera Endophyllum, Gymnosporangium, Microbotryum, Phragmidium, and Pluteus, and the lichen genera Candelariella, Cladonia, Flavoplaca, Lichenothelia, Peltigera, Placolecis, Rinodina, Scytinium, and Solenopsora
Notulae to the Italian flora of algae, bryophytes, fungi and lichens: 9
In this contribution, new data concerning bryophytes, fungi, and lichens of the Italian flora are presented.
It includes new records and confirmations for the bryophyte genera Encalypta, Grimmia, and Riccia, for the fungal genera Hericium, Inocybe, Inocutis, Pluteus, and Russula, and for the lichen genera Bryoria, Farnoldia, Hypocenomyce, Lecania, Paracollema, Peltigera, Sarcogyne, and Teloschistes
Notulae to the Italian flora of algae, bryophytes, fungi and lichens: 5
In this contribution, new data concerning bryophytes, fungi, and lichens of the Italian flora are presented. It includes new records and confirmations for the bryophyte genera Diplophyllum and Ptychostomum, the fungal genera Arrhenia, Gymnosporangium, and Sporidesmium and the lichen genera Arthonia, Coenogonium, Flavoplaca, Gyalolechia, Parmotrema, Peltigera, Pterygiopsis, Squamarina, Tornabea, and Waynea
Notulae to the Italian flora of algae, bryophytes, fungi and lichens: 12
In this contribution, new data concerning bryophytes, fungi and lichens of the Italian flora are presented. It includes new records, confirmations or exclusions for the bryophyte genera Acaulon, Campylopus, En-tosthodon, Homomallium, Pseudohygrohypnum, and Thuidium, the fungal genera Entoloma, Cortinarius, Mycenella, Oxyporus, and Psathyrella and the lichen genera Anaptychia, Athallia, Baeomyces, Bagliettoa, Calicium, Nephroma, Pectenia, Phaeophyscia, Polyblastia, Protoparmeliopsis, Pyrenula, Ramalina, and San-guineodiscus
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