Quasar Evolution Driven by Galaxy Encounters in Hierarchical Structures

We link the evolution of the galaxies in the hierarchical clustering scenario with the changing accretion rates of cold gas onto the central massive black holes that power the quasars. We base on galaxy interactions as main triggers of accretion; the related scaling laws are taken up from Cavaliere & Vittorini (2000), and grafted to a semi-analytic code for galaxy formation. As a result, at high $z$ the protogalaxies grow rapidly by hierarchical merging; meanwhile, much fresh gas is imported and also destabilized, so the holes are fueled at their full Eddington rates. At lower $z$ the galactic dynamical events are mostly encounters in hierarchically growing groups; now the refueling peters out, as the residual gas is exhausted while the destabilizing encounters dwindle. So, with no parameter tuning other than needed for stellar observables, our model uniquely produces at $z>3$ a rise, and at $z\lesssim 2.5$ a decline of the bright quasar population as steep as observed. In addition, our results closely fit the observed luminosity functions of quasars, their space density at different magnitudes from $z\approx 5$ to $z\approx 0$, and the local $m_{BH}-\sigma$ relation.Comment: 5 pages. Accepted for publication in ApJ Letter

Oral platelet gel supernatant plus supportive medical treatment versus supportive medical treatment in the management of radiation-induced oral mucositis: a matched explorative active control trial by propensity analysis

OBJECTIVES:: In this active control trial, the rate of radio-induced WHO grade 3/4 oral mucositis and the change in quality of life, assessed by OMWQ-HN, were measured in subjects with head and neck cancer treated by platelet gel supernatant (PGS) and supportive medical treatment versus subjects treated by supportive medical treatment alone. MATERIALS AND METHODS:: Eighty patients with nonmetastatic head and neck cancer underwent curative or adjuvant radiotherapy. All patients underwent supportive medical treatment and/or PGS at the beginning and during radiotherapy. Sixteen patients received PGS in association with supportive medical treatment. To obtain 2 groups virtually randomized for important clinical characteristics subjects were matched, by propensity analysis, with a group of subjects (64 patients) treated with supportive medical treatment alone. RESULTS:: Subjects treated with standard supportive treatment experienced significant higher WHO grade 3/4 toxicity (55%; 35/64) than subjects treated by PGS (13%; 3/16). The reduced toxicity found in PGS group paralleled with the evidence that they developed later symptoms with respect to controls. The Cox proportional hazard model indicated that patients treated with standard supportive medical treatment experienced 2.7-fold increase (hazard ratio=2.7; 95% confidence interval, 1.3-5.7) in the occurrence of WHO grade 3/4 toxicity. PGS group significantly experienced higher quality of life than control groups as measured by OMWQ-HN. A significant decrease in the opioid analgesics usage was found in the PGS group. CONCLUSIONS:: These preliminary data should be interpreted with caution and could serve as a framework around which to design future trials

A Geant4 simulation code for simulating optical photons in SPECT scintillation detectors

Geant4 is an object oriented toolkit created for the simulation of High-Energy Physics detectors. Geant4 allows an accurate modeling of radiation sources and detector devices, with easy configuration and friendly interface and at the same time with great accuracy in the simulation of physical processes. While most Monte Carlo codes do not allow the simulation of the transport and boundary characteristics for optical photons transport generated by scintillating crystal, Geant4 allows the simulation of the optical photons. In this paper we present an application of the Geant4 program for simulating optical photons in SPECT cameras. We aim to study the light transport within scintillators, photomultiplier tubes and coupling devices. To this end, we simulated a detector based on a scintillator, coupled to a photomultiplier tube through a glass window. We compared simulated results with experimental data and theoretical models, in order to verify the good matching with our simulations. We simulated a pencil beam of 140 keV photons impinging the crystal at different locations. For each condition, we calculated the value of the Pulse Height Centroid and the spread of the charge distribution, as read out by the anode array of the photomultiplier. Finally, the spatial and the energy resolutions of the camera have been estimated by simulated data. In all cases, we found that simulations agree very well with experimental data

Fatty acid composition and fat content in milk from cows grazing in the Alpine region

The variation in the fat profile of pooled milk from cows grazing in pastures in June and July at 400\u2013700\ua0m and at 1400\u20132250\ua0m of altitude was evaluated by gas chromatography and compared with that from cows stalled in barns and fed with a diet without fresh grass. The ratios unsaturated/saturated fatty acid in milk samples were 1.33, 1.71 and 1.69 in June and 1.21, 1.69 and 1.84 in July for cows fed with prepared\ua0diet, grazing at 400\u2013700\ua0m or grazing at 1400\u20132250\ua0m, respectively. Analogously, the ratios (oleic plus stearic acid)/palmitic acid were, for the same group of cows, 0.59, 0.72 and 0.78 in June and 0.56, 0.73 and 0.81 in July. In milk from pastured cows, the percentage of oleic, vaccenic, rumenic and \u3b1-linolenic acids increased as a function of the altitude; instead, that of linoleic acid and of cis-12-octadecenoic acid decreased. The yield of fat was always highest in milk from 1400 to 2250\ua0m of altitude (up to 3.6\ua0g per 100\ua0mL). For the milk collected in July at 1400\u20132250\ua0m of altitude, it was observed a decrease in the percentage of decanoic (capric) and dodecanoic acids and an increase in pentadecanoic, stearic, arachidic and docosanoic (behenic) acids. Possible reasons for the differences observed in the milk samples were discussed

Photodetector and scintillation crystals requirements for gamma-ray imaging

The diffusion of the PET and SPET techniques in different applications, like investigation on small organs and tissues or animal imaging, has induced in the past years the researchers to develop modular scintillation cameras to have compactness and versatility in order to obtain dimensions and configurations suitable to the particular application. To this purpose different photodetectors have been studied, as an alternative to the photomultiplier tubes (PMT) based on semiconductor technology. At the same time new scintillating crystals have been tested to match the requirements like high light yield or fast decay time, needed for SPET and PET application, respectively. In this paper we have investigated the photodetector and scintillation crystals requirements to optimize a gamma-ray imager based on scintillation crystals. To this aim we show results about the principal parameters characterizing a gamma-ray imaging, like energy and spatial resolution. The performances of a continuous LaBr3:Ce crystal (49×49×4mm3+3mm glass window) are compared to the ones from a pixellated and continuous NaI:Tl crystal, coupled to multi-anode photomultiplier tube (Hamamatsu H8500 MA-PMT). Furthermore the results are supported with Monte Carlo simulations. With the lanthanum detector, we obtain 1.1mm of intrinsic spatial resolution, comparable with that predicted by the MC simulations. We test also the new ultra bialkali PMT Hamamatsu R7600-200 with a QE = 42%, obtaining an improvement in terms of energy resolution of about 25%, respect to a standard PMT, with a LaBr3:Ce cylinder (1/2" ��φ × 1/2" thickness)

Early Hierarchical Formation of Massive Galaxies Triggered By Interactions

To address the problem concerning the early formation of stars in massive galaxies, we present the results of a semi-analytic model of galaxy formation which includes a physical description of starbursts triggered by galaxy interactions. These originate from the destabilization of cold galactic gas occurring in galaxy encounters, which in part feeds the accretion onto black holes powering quasars, and in part drives circumnuclear starsbursts at redshifts $z\approx 2-4$, preferentially in massive objects. This speeds up the formation of stars in massive galaxies at high redshifts without altering it in low mass galactic halos. Thus, at intermediate $z\approx 1.5-2$ we find that a considerable fraction of the stellar content of massive galaxies is already in place, at variance with the predictions of previous hierarchical models. The resulting high-$z$ star formation rate and B-band luminosity functions, and the luminosity and redshift distribution of galaxies in K-band at $z\lesssim 2$ are all in good agreement with the existing observations concerning the bright galaxy population.Comment: 7 pages, accepted for publication in Ap

Powerful high energy emission of the remarkable BL Lac object S5 0716+714

BL Lac objects of the intermediate subclass (IBLs) are known to emit a substantial fraction of their power in the energy range 0.1--10 GeV. Detecting gamma-ray emission from such sources provides therefore a direct probe of the emission mechanisms and of the underlying powerhouse. The AGILE gamma-ray satellite detected the remarkable IBL S5 0716+714 (z \simeq 0.3) during a high state in the period from 2007 September - October, marked by two very intense flares reaching peak fluxes of 200\times10^{-8} ph / cm^2 s above 100 MeV, with simultaneous optical and X-ray observations. We present here a theoretical model for the two major flares and discuss the overall energetics of the source. We conclude that 0716+714 is among the brightest BL Lac's ever detected at gamma-ray energies. Because of its high power and lack of signs for ongoing accretion or surrounding gas, the source is an ideal candidate to test the maximal power extractable from a rotating supermassive black hole via the pure Blandford-Znajek (BZ) mechanism. We find that during the 2007 gamma-ray flares our source approached or just exceeded the upper limit set by BZ for a black hole of mass 10^9 M_sunComment: 12 pages, 3 figure