41 research outputs found
Tucked In Tight: NON-PHARMACOLOGICAL RELAXATION TECHNIQUES IN OLDER ADULT PATIENTS \u3e65
- Publication venue
- LVHN Scholarly Works
- Publication date
- 06/11/2015
- Field of study
Psychology in the Courtroom: The Effects of Personal Information on Jurors\u27 Verdicts and Perceptions of a Defendant
- Publication venue
- Digital Commons @ IWU
- Publication date
- 13/04/1996
- Field of study
Interdisciplinary Perspectives for Broadening the Scientific Research Base in Science Education 1 2
- Publication venue
- Publication date
- 06/03/2020
- Field of study
A population of gamma-ray emitting globular clusters seen with the Fermi Large Area Telescope
- Author
- Abdo Aous A.
- Ackermann Markus
- Ajello Marco
- Baldini Luca
- Ballet Jean
- Barbiellini Guido
- Bastieri Denis
- Bellazzini Ronaldo
- Blandford Roger D.
- Bloom Elliott D.
- Bonamente Emanuele
- Borgland Anders W.
- Bouvier Aurelien
- Brandt Theresa J.
- Bregeon Jean
- Brigida Monica
- Bruel Philippe
- Buehler Rolf
- Buson Sara
- Caliandro Giuseppe Andrea
- Cameron Robert A.
- Caraveo Patrizia A.
- Carrigan Svenja
- Casandjian Jean-Marc
- Charles Eric
- Chaty Sylvain
- Chekhtman Alexandre
- Cheung C. C. Teddy
- Chiang James
- Ciprini Stefano
- Claus Rachel
- Cohen-Tanugi Johan
- Conrad Jan
- Couto e Silva Eduardo do
- DeCesar Megan E.
- Dermer Charles Dennison
- Digel Seth W.
- Drell Persis S.
- Dubois Richard
- Dumora Denis
- Favuzzi Cecilia
- Fortin Pascal
- Frailis Marco
- Fukazawa Yasushi
- Fusco Piergiorgio
- Gargano Fabio
- Gasparrini Dario
- Gehrels Neil
- Germani Stefano
- Giglietto Nicola
- Giordano Francesco
- Glanzman Tom
- Godfrey Gary
- Grenier Isabelle A.
- Grondin Marie-Hélène
- Grove J. Eric
- Guillemot Lucas
- Guiriec Sylvain
- Hadasch Daniela
- Harding Alice K.
- Hays Elizabeth
- Jean Pierre
- Johannesson Gueolaugur
- Johnson Tyrel J.
- Johnson W. Neil
- Kamae Tuneyoshi
- Katagiri Hideaki
- Kataoka Jun
- Kerr Matthew
- Knödlseder Jürgen
- Kuss M.
- Lande Joshua
- Latronico Luca
- Lee Shiu-Hang
- Lemoine-Goumard Marianne
- Llena-Garde Maja
- Longo Francesco
- Loparco Francesco
- Lovellette Michael N.
- Lubrano Pasquale
- Makeev Andrey
- Mazziotta Mario Nicola
- Michelson Peter F.
- Mitthumsiri Warit
- Mizuno Takafumi
- Monte Claudia
- Monzani Maria Elena
- Morselli Aldo
- Moskalenko Igor V.
- Murgia Simona
- Naumann-Godo Melitta
- Nolan Pat L.
- Norris Jay P.
- Nuss Eric
- Ohsugi Takashi
- Omodei Nicola
- Orlando Elena
- Ormes Jonathan F.
- Palma Francesco de
- Pancrazi Benoit
- Parent D.
- Pepe Monica
- Pesce-Rollins Melissa
- Piron Frédéric
- Porter Troy A.
- Rainò Silvia
- Rando Riccardo
- Reimer Anita
- Reimer Olaf
- Reposeur Thierry
- Ripken Joachim
- Romani Roger W.
- Roth Marshall
- Sadrozinski Hartmut F. W.
- Saz Parkinson Pablo M.
- Sgrò Carmelo
- Siskind Eric J.
- Smith David A.
- Spinelli Paolo
- Strickman Mark Samuel
- Suson Daniel Jeffrey
- Takahashi Hiromitsu
- Takahashi Tadayuki
- Tanaka Takaaki
- Thayer Jana B.
- Thayer John Gregg
- Tibaldo Luigi
- Torres Diego F.
- Tosti Gino
- Tramacere Andrea
- Uchiyama Yasunobu
- Usher Tracy L.
- Vasileiou Vlasios
- Venter Christo
- Vilchez Nicolás
- Vitale Vincenzo
- Waite Anthony P.
- Wang Ping
- Webb Natalie
- Winer Brian L.
- Yang Zhaoyu
- Ylinen Tomi
- Ziegler Marcus
- Publication venue
- 'EDP Sciences'
- Publication date
- 01/01/2010
- Field of study
Globular clusters with their large populations of millisecond pulsars (MSPs)
are believed to be potential emitters of high-energy gamma-ray emission. Our
goal is to constrain the millisecond pulsar populations in globular clusters
from analysis of gamma-ray observations. We use 546 days of continuous
sky-survey observations obtained with the Large Area Telescope aboard the Fermi
Gamma-ray Space Telescope to study the gamma-ray emission towards 13 globular
clusters. Steady point-like high-energy gamma-ray emission has been
significantly detected towards 8 globular clusters. Five of them (47 Tucanae,
Omega Cen, NGC 6388, Terzan 5, and M 28) show hard spectral power indices (0.7<Γ<1.4) and clear evidence for an exponential cut-off in the range
1.0-2.6 GeV, which is the characteristic signature of magnetospheric emission
from MSPs. Three of them (M 62, NGC 6440 and NGC 6652) also show hard spectral
indices (1.0<Γ<1.7), however the presence of an exponential cut-off
can not be unambiguously established. Three of them (Omega Cen, NGC 6388, NGC
6652) have no known radio or X-ray MSPs yet still exhibit MSP spectral
properties. From the observed gamma-ray luminosities, we estimate the total
number of MSPs that is expected to be present in these globular clusters. We
show that our estimates of the MSP population correlate with the stellar
encounter rate and we estimate 2600-4700 MSPs in Galactic globular clusters,
commensurate with previous estimates. The observation of high-energy gamma-ray
emission from a globular cluster thus provides a reliable independent method to
assess their millisecond pulsar populations that can be used to make
constraints on the original neutron star X-ray binary population, essential for
understanding the importance of binary systems in slowing the inevitable core
collapse of globular clusters.Comment: Accepted for publication in A&A. Corresponding authors: J.
Kn\"odlseder, N. Webb, B. Pancraz
Lp-PLA2 activity is associated with increased risk of diabetic retinopathy:a longitudinal disease progression study
- Author
- A Thompson
- AB Hill
- Alexander S. F. Doney
- Andrew D. Morris
- B Miljanovic
- BA Furlani
- CJ Packard
- CK Kramer
- Colin N. A. Palmer
- DB Mukamel
- DR Cox
- E Chen
- ER Schoenfeld
- Ewan R. Pearson
- EY Chew
- Fiona Carr
- G Staurenghi
- GP Leese
- Gwen Kennedy
- Heart Protection Study Collaborative Group
- JM Lopes de Faria
- JP Fine
- JWY Yau
- Megan M. McLaughlin
- MJ Elman
- Moneeza K. Siddiqui
- MW Johnson
- NK Acharya
- P Canning
- P Mitchell
- QD Nguyen
- R Klein
- R Klein
- R Klein
- R Varma
- R Williams
- Rachel E. Williams
- RJ Brechner
- S Vitale
- TA Ciulla
- Toby Johnson
- W Koenig
- Y Liu
- Y Zheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 06/04/2018
- Field of study
Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas
- Author
- A Orioli
- A Woiwode
- AG Winter
- AJ Copp
- Anne E. Willis
- Ayala King
- C Fernandez-Tornero
- C Lopez-Garcia
- Carolyn Jones
- CG Larminie
- CJ Clarke
- D Athineos
- D Athineos
- D Crighton
- David Stevenson
- Douglas Strathdee
- Dritan Liko
- EJ Rideout
- EP Geiduschek
- F Bellido
- F Schwenk
- G Abascal-Palacios
- G Dieci
- GA Kassavetis
- GA Kassavetis
- GK Michalopoulos
- H Ireland
- H Schachtner
- HJ Snippert
- I Vitale
- J Birch
- J Heijmans
- JA Fairley
- JA Fairley
- JE Sutcliffe
- Jennifer P. Morton
- JL Park
- JM Park
- John R. P. Knight
- JP Morton
- JR Matthews
- K Takaoka
- K Yanger
- KA Spriggs
- Karen Blyth
- Kate Dudek
- Kirsteen J. Campbell
- KL Tucker
- L Marshall
- L Schramm
- L Schramm
- Louise Mitchell
- LR Versteegh
- M Pavon-Eternod
- M Pavon-Eternod
- M Teichmann
- M Werner
- Megan J. Bywater
- MK Vorländer
- MR Bosl
- N Gomez-Roman
- N Saiz
- NS Kenneth
- NS Yee
- OJ Sansom
- Owen J. Sansom
- P Cramer
- Q Zhong
- Rachel A. Ridgway
- RD Moir
- RJ White
- RJ White
- RJ White
- S Sriskanthadevan-Pirahas
- S Walz
- SA Johnson
- Sheila Bryson
- SJ Goodfellow
- SK Bronson
- SL Wolin
- SR Hingorani
- SR Hingorani
- T Hay
- Thomas G. Bird
- TM Magin
- W Chen
- WY Lu
- Z Bloom-Ackermann
- Z Fang
- ZA Felton-Edkins
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 11/03/2019
- Field of study
RNA polymerase III (Pol-III) transcribes tRNAs and other small RNAs essential for protein synthesis and cell growth. Pol-III is deregulated during carcinogenesis; however, its role in vivo has not been studied. To address this issue, we manipulated levels of Brf1, a Pol-III transcription factor that is essential for recruitment of Pol-III holoenzyme at tRNA genes in vivo. Knockout of Brf1 led to embryonic lethality at blastocyst stage. In contrast, heterozygous Brf1 mice were viable, fertile and of a normal size. Conditional deletion of Brf1 in gastrointestinal epithelial tissues, intestine, liver and pancreas, was incompatible with organ homeostasis. Deletion of Brf1 in adult intestine and liver induced apoptosis. However, Brf1 heterozygosity neither had gross effects in these epithelia nor did it modify tumorigenesis in the intestine or pancreas. Overexpression of BRF1 rescued the phenotypes of Brf1 deletion in intestine and liver but was unable to initiate tumorigenesis. Thus, Brf1 and Pol-III activity are absolutely essential for normal homeostasis during development and in adult epithelia. However, Brf1 overexpression or heterozygosity are unable to modify tumorigenesis, suggesting a permissive, but not driving role for Brf1 in the development of epithelial cancers of the pancreas and gut
Defining the causes of sporadic Parkinson's disease in the global Parkinson's genetics program (GP2)
- Author
- Aasly Jan O.
- Ahmad-Annuar Azlina
- Akpalu Albert
- Albin Roger
- Alcalay Roy
- Alvarez Ignacio
- Amod Ferzana
- Amouri Rim
- Anderson Tim J.
- Antar Tarek
- Arboleda Gonzalo
- Atadzhanov Masharip
- Avenali Micol
- Awad Paula Saffie
- Azmin Shahrul
- Baak A. Nazl
- Bale Claire
- Bandres-Ciga Sara
- Bardien Soraya
- Beach Thomas
- Beyer Katrin
- Blauwendraat Cornelis
- Borgohain Rupam
- Brice Alexis
- Bustamante Maria Leonor
- Camargos Sarah
- Carr Jonathan
- Carroll Camille
- Casey Bradford
- Chahine Lana M.
- Chan Germaine Hiu-Fai
- Chan Phillip
- Chan Piu
- Chana Pedro
- Chen Honglei
- Cheung Nelson Yuk-Fai
- Chowdhury Sohini
- Comart Charisse
- Cornejo-Olivas Mario
- Corvol Jean-Christophe
- Cruchaga Carlos
- Cubo Esther
- Dadiotis Efthymios
- Dagklis Ioannis
- Dean Marissa
- del Rio Marlene Jimenez
- Dey Sumit
- Doquenia Maria Leila
- Dumanis Sonya
- El-Sadig Sarah
- Ellis Melina
- Ertan Sibel
- Espay Alberto
- Faghri Faraz
- Fang Zih-Hua
- Fiske Brian
- Fon Edward A.
- Fon Ted
- Foo Jia Nee
- Foroud Tatiana
- Funayama Manabu
- Galleguillos Benjamin Pizarro
- Gasser Thomas
- Gatto Emilia M.
- Genc Gencer
- Groppa Sergiu
- Grosset Donald
- Guo Jifeng
- Hadjigorgiou Georgios
- Hall Deborah
- Hardy John
- Hattori Nobutaka
- Hernandez Alvaro
- Hernandez Dena
- Hernandez Dena G.
- Hoenicka Janet
- Hopfner Franziska
- Houlden Henry
- Hunter Julie
- Höglinger Günter
- Iakovenko Elena
- Ibanez Laura
- Illarionova Anastasia
- Inca-Martinez Miguel
- Ip Nancy
- Iwaki Hirotaka
- Jankovic Joseph
- Jasaitye Simona
- Jasaityte Simona
- Jeon Beomseok
- Jonas Cabell
- Joubert Julie
- Junker Johanna
- Kaishibayeva Gulnaz
- Kaiyrzhanov Rauan
- Kamel Walaa A.
- Karimova Altynay
- Kauffman Marcelo
- Khachatryan Samson
- Kieburtz Karl
- Kim Jonggeol Jeff
- Kim Yun Joong
- Kishore Asha
- Klein Christine
- Koks Sulev
- Koretsky Mathew
- KP Divya
- Krack Paul
- Krüger Rejko
- Kuhl Maggie
- Kukkle Prashanth Lingappa
- Kumar Kishore
- Kung Pin-Jui
- Lange Lara M.
- Leonard Hampton
- Levine Kristin
- Levine Kristin S.
- Lewis Patrick Alfryn
- Lim Shen-Yang
- Lin Chin-Hsien
- Lohmann Katja
- Louie Naomi
- Love Seth
- Lubbe Steven
- Luo Wei
- Madoev Harutyun
- Makarious Mary B.
- Marek Kenneth
- Markopoulou Katerina
- Marsili Luca
- Martinez-Carrasco Alejandro
- Martinez-Ramirez Daniel
- Mata Ignacio F.
- Medina Alex
- Mencacci Niccolò Emanuele
- Miranda Marcelo
- Mohamed Wael
- Mok Kin Ying
- Mollenhauer Brit
- Monchi Oury
- Morris Huw R.
- Mubarak Bashayer Al
- Murad Nor Azian Abdul
- Murphy Kaileigh
- Nalls Mike A.
- Nguyen Duan
- Nguyen Toan
- Norlinah Mohamed Ibrahim
- Noyce Alastair
- Nuytemans Karen
- O'Grady Alyssa
- Obese Vida
- Ojha Rajeev
- Ojo Oluwadamilola
- Okubadejo Njideka
- Okunoye Olaitan
- Olguin Patricio
- Orozco Jorge
- Pal Pramod
- Pantazis Caroline B.
- Parnetti Lucilla
- Pastor Pau
- Periñan Maria Teresa
- Pihlstrøm Lasse
- Pitcher Toni L.
- Puckelwartz Megan J.
- Quattrone Andrea
- Rajan Roopa
- Rentería Miguel E.
- Reyes-Pérez Paula
- Richer Madeleine
- Rieder Carlos
- Riley Ekemini
- Rizig Mie
- Rodriguez-Violante Mayela
- Rosales Raymond
- Ruffrage Lauren
- Salama Mohamed
- Salari Mehri
- Sanyaolu Arinola
- Sarmiento Ignacio Juan Keller
- Sassi Samia Ben
- Schapira Anthony
- Schirinzi Tommaso
- Schrag Anette
- Schumacher-Schuh Artur F.
- Screven Laurel
- Screven Laurel A.
- Serrano Geidy E.
- Shambetova Cholpon
- Shang Huifang
- Sharma Manu
- Shepherd Claire E.
- Sherer Todd
- Shiamim Ejaz
- Shiraishi Tomotaka
- Shulman Joshua
- Shulman Lisa
- Siddiqi Bernadette
- Singleton Andrew B.
- Sobering Andrew K.
- Solle Justin
- Solle Justin C.
- Song Yeajin
- Stafford Eleanor J.
- Stamelou Maria
- Stefanis Leonidas
- Stott Simon
- Tan Ai Huey
- Tan Eng-King
- Tan Manuela
- Tan Manuela M. X.
- Tang Beisha
- Tarnanas Ioannis
- Tavadyan Zaruhi
- Tay Yi Wen
- Towns Clodagh
- Trinh Joanne
- Tserensodnom Bayasgalan
- Tumas Vitor
- Umair Muhammad
- Ur-Rehman Shoaib
- Valente Enza Maria
- Vinuela Angel
- Vitale Dan
- Vollstedt Eva-Juliane
- Walker Ruth
- Wegel Claire
- Wegel Claire E.
- Weil Rimona
- Westenberger Ana
- Williams Nigel
- Williamson Jared
- Wood Nicholas
- Wu Hsiu-Chuan
- Wu Ruey-Meei
- Wu Yihru
- Xie Tao
- Xiromerisiou Georgia
- Zewde Yared Z.
- Zhou Xiaopu
- Zimprich Alexander
- Zweier Christiane
- Çakmak Özgür Öztop
- Publication venue
- Publication date
- 12/09/2023
- Field of study
The Global Parkinson’s Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia
Multi-ancestry genome-wide association meta-analysis of Parkinson?s disease
- Author
- Aasly Jan O.
- Ahmad-Annuar Azlina
- Akpalu Albert
- Albin Roger
- Alcalay Roy
- Alvarez Ignacio
- Amod Ferzana
- Amouri Rim
- Anderson Tim J.
- Arboleda Gonzalo
- Aslibekyan Stella
- Atadzhanov Masharip
- Auton Adam
- Avenali Micol
- Awad Paula Saffie
- Azmin Shahrul
- Baak A. Nazl
- Babalola Elizabeth
- Bale Claire
- Bandres-Ciga Sara
- Bardien Soraya
- Beach Thomas
- Bell Robert K.
- Beyer Katrin
- Bielenberg Jessica
- Blauwendraat Cornelis
- Borgohain Rupam
- Brice Alexis
- Brolin Kajsa
- Bryc Katarzyna
- Bullis Emily
- Bustamante Maria Leonor
- Camargos Sarah
- Cannon Paul
- Carr Jonathan
- Carroll Camille
- Casey Bradford
- Chahine Lana M.
- Chan Germaine Hiu-Fai
- Chan Phillip
- Chan Piu
- Chana Pedro
- Chen Honglei
- Cheung Nelson Yuk-Fai
- Chowdhury Sohini
- Coker Daniella
- Comart Charisse
- Cornejo-Olivas Mario
- Corvol Jean-Christophe
- Cruchaga Carlos
- Cubo Esther
- Dadiotis Efthymios
- Dagklis Ioannis
- Das Sayantan
- Dean Marissa
- del Rio Marlene Jimenez
- Dey Sumit
- Dhamija Devika
- Divya K. P.
- Doquenia Maria Leila
- Dumanis Sonya
- El-Sadig Sarah
- Ellis Melina
- Elson Sarah L.
- Eriksson Nicholas
- Ertan Sibel
- Espay Alberto
- Faghri Faraz
- Fang Zih-Hua
- Filshtein Teresa
- Fiske Brian
- Fitch Alison
- Fletez-Brant Kipper
- Fon Edward A.
- Fon Ted
- Fontanillas Pierre
- Foo Jia Nee
- Foroud Tatiana
- Freyman Will
- Funayama Manabu
- Galleguillos Benjamin Pizarro
- Gasser Thomas
- Gatto Emilia M.
- Genc Gencer
- Granka Julie M.
- Groppa Sergiu
- Grosset Donald
- Guo Jifeng
- Hadjigorgiou Georgios
- Hall Deborah
- Hardy John
- Hattori Nobutaka
- Heilbron Karl
- Hernandez Alejandro
- Hernandez Alvaro
- Hernandez Dena
- Hicks Barry
- Hinds David A.
- Hoenicka Janet
- Hopfner Franziska
- Houlden Henry
- Hunter Julie
- Höglinger Günter
- Iakovenko Elena
- Ibanez Laura
- Illarionova Anastasia
- Inca-Martinez Miguel
- Ip Nancy
- Iwaki Hirotaka
- Jankovic Joseph
- Jasaityte Simona
- Jeon Beomseok
- Jewett Ethan M.
- Jiang Yunxuan
- Jonas Cabell
- Junker Johanna
- Kaishibayeva Gulnaz
- Kaiyrzhanov Rauan
- Kamel Walaa A.
- Karimova Altynay
- Kauffman Marcelo
- Khachatryan Samson
- Kieburtz Karl
- Kim Jonggeol Jeffrey
- Kim Yun Joong
- Kishore Asha
- Klein Christine
- Koks Sulev
- Koretsky Mathew
- Krack Paul
- Krüger Rejko
- Kuhl Maggie
- Kukar Katelyn
- Kukkle Prashanth Lingappa
- Kumar Kishore
- Kung Pin-Jui
- Kwong Alan
- Lake Julie
- Lange Lara M.
- Leonard Hampton
- Levine Kristin S.
- Lewis Patrick Alfryn
- Lian Michelle Mulan
- Lim Shen-Yang
- Lin Chin-Hsien
- Lin Keng-Han
- Llamas Bianca A.
- Lohmann Katja
- Louie Naomi
- Love Seth
- Lowe Maya
- Lubbe Steven
- Luo Wei
- Madoev Harutyun
- Makarious Mary B.
- Marek Kenneth
- Markopoulou Katerina
- Marsili Luca
- Martinez-Ramirez Daniel
- Martínez-Carrasco Alejandro
- Mata Ignacio
- Mata Ignacio F.
- McCreight Jey C.
- McIntyre Matthew H.
- Medina Alex
- Mencacci Niccolò Emanuele
- Micheletti Steven J.
- Miranda Marcelo
- Mohamed Wael
- Mok Kin Ying
- Mollenhauer Brit
- Monchi Oury
- Moreno Meghan E.
- Morris Huw R.
- Mubarak Bashayer Al
- Murad Nor Azian Abdul
- Murphy Kaileigh
- Nalls Mike A.
- Nandakumar Priyanka
- Nguyen Dominique T.
- Nguyen Duan
- Nguyen Toan
- Noblin Elizabeth S.
- Norlinah Mohamed Ibrahim
- Noyce Alastair J.
- Nuytemans Karen
- O'Connell Jared
- O'Grady Alyssa
- Obese Vida
- Ojha Rajeev
- Ojo Oluwadamilola
- Okubadejo Njideka
- Okunoye Olaitan
- Olguin Patricio
- Orozc Jorge
- Otani Diego Véliz
- Pal Pramod
- Pantazis Caroline B.
- Parnetti Lucilla
- Partida Gabriel Cuellar
- Pastor Pau
- Periñan Maria Teresa
- Petrakovitz Aaron A.
- Pihlstrøm Lasse
- Pitcher Toni L.
- Poznik G. David
- Puckelwartz Megan J.
- Quattrone Andrea
- Rajan Roopa
- Rentería Miguel E.
- Reyes-Pérez Paula
- Reynoso Alexandra
- Rieder Carlos
- Riley Ekemini
- Rizig Mie
- Rodriguez-Violante Mayela
- Rosales Raymond
- Ruffrage Lauren
- Salama Mohamed
- Salari Mehri
- Sanyaolu Arinola
- Sarmiento Ignacio Juan Keller
- Sassi Samia Ben
- Schapira Anthony
- Schirinzi Tommaso
- Schloetter Madeleine
- Schrag Anette
- Schumacher Morgan
- Schumacher-Schuh Artur F.
- Screven Laurel
- Serrano Geidy E.
- Shambetova Cholpon
- Shang Huifang
- Sharma Manu
- Shastri Anjali J.
- Shelton Janie F.
- Shepherd Claire E.
- Sherer Todd
- Shi Jingchunzi
- Shiamim Ejaz
- Shiraishi Tomotaka
- Shringarpure Suyash
- Shulman Joshua
- Shulman Lisa
- Siddiqi Bernadette
- Singleton Andrew B.
- Sobering Andrew K.
- Solle Justin C.
- Solsberg Caroline Warly
- Song Yeajin
- Stafford Eleanor J.
- Stamelou Maria
- Stefanis Leonidas
- Stott Simon
- Su Qiaojuan Jane
- Tan Ai Huey
- Tan Eng-King
- Tan Manuela
- Tang Beisha
- Tarnanas Ioannis
- Tat Susana A.
- Tavadyan Zaruhi
- Tay Yi Wen
- Tchakouté Christophe Toukam
- Tinkhauser Gerd
- Tran Vinh
- Trinh Joanne
- Tserensodnom Bayasgalan
- Tumas Vitor
- Tung Joyce Y.
- Umair Muhammad
- Ur-Rehman Shoaib
- Valente Enza Maria
- Veliz-Otani Diego
- Vinuela Angel
- Vitale Dan
- Vollstedt Eva-Juliane
- Walker Ruth
- Wang Wei
- Wang Xin
- Wegel Claire
- Weil Rimona
- Weldon Catherine H.
- Westenberger Ana
- Williams Nigel
- Williamson Jared
- Wilton Peter
- Wong Corinna D.
- Wood Nicholas
- Wu Hsiu-Chuan
- Wu Ruey-Meei
- Wu Yihru
- Xie Tao
- Xiromerisiou Georgia
- Zewde Yared Z.
- Zhou Xiaopu
- Zimprich Alexander
- Zweier Christiane
- Çakmak Özgür Öztop
- Publication venue
- Nature Research
- Publication date
- 31/01/2024
- Field of study
Although over 90 independent risk variants have been identified for Parkinson’s disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-analysis of Parkinson’s disease with 49,049 cases, 18,785 proxy cases and 2,458,063 controls including individuals of European, East Asian, Latin American and African ancestry. In a meta-analysis, we identified 78 independent genome-wide significant loci, including 12 potentially novel loci (MTF2, PIK3CA, ADD1, SYBU, IRS2, USP8, PIGL, FASN, MYLK2, USP25, EP300 and PPP6R2) and fine-mapped 6 putative causal variants at 6 known PD loci. By combining our results with publicly available eQTL data, we identified 25 putative risk genes in these novel loci whose expression is associated with PD risk. This work lays the groundwork for future efforts aimed at identifying PD loci in non-European populations
Observation of gravitational waves from the coalescence of a 2.5−4.5 M⊙ compact object and a neutron star
- Author
- Abac Adrian
- Abbott R.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aghaei Abchouyeh Maryam
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akcay Sarp
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi Simone
- Alex iandolo Guido
- Alfaidi Reem Atallah E
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- Wu Hsun-Chung
- Wuchner E.
- Wysocki Daniel
- Xu Victoria
- Xu Yumeng
- Yaala M. Ben
- Yadav Nikesh
- Yamamoto Hiroaki
- Yamamoto Kazuhiro
- Yamamoto Takahiro
- Yamamoto Takahiro S.
- Yamamura S.
- Yamazaki Ryo
- Yan S.
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- Yang Fengwei
- Yang Kate Z.
- Yang Yi
- Yarbrough Zach
- Yasui H.
- Yeh S. -W.
- Yelikar A. B.
- Yin X.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yu Hang
- Yuan S.
- Yuzurihara Hirotaka
- Zadrożny A.
- Zanolin M.
- Zeeshan M.
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- Zeoli M.
- Zerrad M.
- Zevin Michael
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- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Zweizig John
- Árpád Gergely László
- 劉 國欽
- 都丸 隆行
- Publication venue
- Publication date
- 23/04/2024
- Field of study
Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adamcewicz C.
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Almualla M.
- Altin Paul
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Anand S.
- Ananyeva A.
- Andersen R.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Aoumi M.
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Arif Shaikh Md
- Aritomi Naoki
- Armato F.
- Arnaud Nicolas
- Arogeti Megan
- Aronson Scott
- Arun K. G.
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
- Aston S. M.
- Astone Pia
- Aubin Florian
- Babak Stanislav
- Badalyan A.
- Badaracco Francesca
- Badger C.
- Bae Sangwook
- Bagnasco Stefano
- Bai Y.
- Baier Jeremy
- Bajpai Rishabh
- Baka T.
- Ball M.
- Ballardin G.
- Ballmer S. W.
- Baltus Grégory
- Banagiri Sharan
- Banerjee Biswajit
- Bankar Deepak
- Baral Pratyusava
- Barayoga J. C.
- Barber J.
- Barish B. C.
- Barker D.
- Barneo Pablo
- Barone Fabrizio
- Barr Bryan
- Barsotti Lisa
- Barsuglia Matteo
- Barta Dániel
- Barthelmy S. D.
- Barton Mark Andrew
- Bartos I.
- Basak Soummyadip
- Basalaev Artem
- Bassiri Riccardo
- Basti Andrea
- Bawaj Mateusz
- Baxi P.
- Bayley Joseph
- Baylor Amanda
- Bazzan M.
- Bedakihale V. M.
- Beirnaert Freija
- Bejger Michał
- Bell Angus
- Benedetto V.
- Beniwal D.
- Benoit William
- Bentley Joe
- Bera Sayantani
- Berbel Marina
- Bergamin Fabio
- Berger Beverly
- Bernuzzi Sebastiano
- Beroiz Martin
- Berry Christopher P. L.
- Bersanetti Diego
- Bertolini A.
- Betzwieser Joseph
- Beveridge Damon
- Bevins Nathaniel
- Bhandare R.
- Bhandari A. V.
- Bhardwaj Uddipta
- Bhatt R.
- Bhattacharjee Dripta
- Bhaumik Shubhagata
- Bianchi A.
- Bilenko I. A.
- Bilicki Maciej
- Billingsley GariLynn
- Binetti Alberto
- Bini Sophie
- Birnholtz Ofek
- Biscans S.
- Bischi M.
- Biscoveanu Andrea Sylvia
- Bisht A.
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- Blackburn Kent
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- Bobba F.
- Bode Nina
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- Boileau Guillaume
- Boldrini Mattia
- Bolingbroke Georgia
- Bondarescu Ruxandra
- Bondu François
- Bonilla Carrasquel Edgard
- Bonilla G. S.
- Bonnand Romain
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- Boschi Valerio
- Bose S.
- Bossilkov V.
- Boudart Vincent
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- Bradaschia C.
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- Braglia Matteo
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- BRANCHESI Marica
- Breschi Matteo
- Briant Tristan
- Brillet A.
- Brinkmann M.
- Brockill P.
- Brooks Aidan
- Brown D. D.
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- Buchanan J.
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- Buscicchio Riccardo
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- Bustillo J. Calderón
- Buy Christelle
- Bécsy Bence
- C. Utina Andrei
- Cabourn Davies Gareth
- Cabras Giuseppe
- Cabrita Ricardo
- Cadonati Laura
- Cagnoli Gianpietro
- Cahillane Craig
- Cain III. H. W.
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- Callister T. A.
- Calloni E.
- Camp J. B.
- Canepa M.
- Caneva Santoro Giada
- Cannavacciuolo M.
- Cannon Kipp C.
- Cao H.
- Capistran L. A.
- Capocasa Eleonora
- Capote E.
- Carapella G.
- Carbognani F.
- Carlassara M.
- Carlin Julian
- Carolina Silva Oliveira Ana
- Carpinelli Massimo
- Carter Jonathan
- Carullo Gregorio
- Casentini C.
- Castaldi G.
- Castro-Lucas S. Y.
- Caudill S.
- Cavaglia Marco
- Cavalieri Roberto
- Cella Giancarlo
- Cerdá-Durán Pablo
- Cesarini Elisabetta
- Chaibi W.
- Chalathadka Subrahmanya Shreevathsa
- Chan C.
- Chan M.
- Chan W. L.
- Chandra K.
- Chang I. P.
- Chang R. -J.
- Chang W.
- Chanial Pierre
- Chao Shiuh
- Chapman-Bird Christian
- Charlton E. L.
- Charlton Philip
- CHASSANDE-MOTTIN Eric
- Chastain L.
- Chatterjee Chayan
- Chatterjee Debarati
- Chatterjee Deep
- Chaturvedi M.
- Chaty Sylvain
- Chatziioannou Katerina
- Chen A.
- Chen A. H. -Y.
- Chen Dan
- Chen H.
- Chen Hsin-Yu
- Chen Junxin
- Chen K. H.
- Chen X.
- Chen Y.
- Chen Y. -R.
- Cheng H.
- Chessa Piero
- Chia H. Y.
- Chiadini Francesco
- Chiang C.
- Chiarini G.
- Chiba A.
- Chiba R.
- Chierici R.
- Chincarini Andrea
- Chiofalo M. L.
- Chiummo Antonino
- Chou C.
- Choudhary Sunil
- Christensen Nelson
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- Zweizig John
- Álvarez-López S.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/08/2023
- Field of study
Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level