Seguiment del contingut de nitrats al sòl i en planta en parcel·les comercials de panís al Pla d'Urgell

En aquest treball es presenten els resultats parcials del primer any de seguiment de nitrats al sòl i en planta de parcel·les comercials de panís (Zea mays L.) a la zona regable dels canals d'Urgell. Les parcel·les han estat seleccionades a partir del coneixement dels sòls de la zona i com a principal criteri el de la representativitat espaial. L'excés de nitrogen a la zona, present a les capes freàtiques i a la xarxa de reg i de drenatges, ve donat per l'aplicació en excés de nitrogen als cultius, entre els quals el panís és un dels més importants. A les parcel·les seguides s'han aplicat dosis de nitrogen que van dels 250 als 350 kg N/ha. Els primers resultats mostren com les aplicacions que fan els agricultors són independents de les disponibilitats inicials de nitrogen al sòl. També es mostra com la determinació de nitrats a la base de la tija al final del cicle pot servir per conèixer si les disponibilitats de N han estat excessives. Els rendiments més elevats, 13,5 Mg/ha, han coincidit amb les aplicacions de N més baixes, les disponibilitats de nitrogen també més baixes i amb el contingut de nitrats a la base de la tija més baix (0,4 g NNO3/ kg). Tot això demostra que la racionalització de l'ús del nitrogen és possible.En este trabajo se presentan los resultados parciales del primer año de seguimiento de nitratos en el suelo y en planta de parcelas comerciales de maíz (Zea mays L.) en la zona regable de los canales de Urgell. Las parcelas han sido seleccionadas a partir del conocimiento de los suelos de la zona y como criterio principal el de su representatividad espacial. El exceso de nitrógeno en la zona, presente en las capas freáticas y en la red de riego y de drenajes viene dado por la aplicación en exceso de nitróge-no a los cultivos, dentro de los cuales el maíz es uno de los más importantes. En las parcelas seguidas se han aplicado dosis de nitrógeno que van de los 250 a los 350 kg N/ha. Los primeros resultados muestran como las aplicaciones que hacen los agricultores son independientes de las disponibilidades iniciales de nitrógeno en el suelo. También se muestra como la determinación de nitratos en la base del tallo al final del ciclo puede servir para conocer si las disponibilidades de N han sido excesivas. Los rendimientos más elevados 13,5 Mg/ha han coincidido con las aplicaciones de N más bajas, las disponibilidades de nitrógeno también más bajas y con el contenido de nitratos en la base del tallo más bajo (0,4 g N-NO3/kg). Todo esto demuestra que la racionalización del uso del nitrógeno es posible.This paper presents the partial results of the first year monitoring of soil and plant nitrate contents in commercial maize (Zea mays L.) in the Urgell canal irrigated area. The fields have been selected starting from the knowledge of the soils in the area and their spatial representativeness as main criteria. The excess of nitrogen in the area, present in the groundwater as well as in the irrigation water, is due to overfertilisation of the crops, of which maize is one of the most importants. In the monitored fields the applied nitrogen fertiliser ranges from 250 to 350 kg/ha. The first results show that the farmers’ applications are not related to the initially available soil nitrogen. They also show how the determination of nitrates in the lower part of the stem at the end of the cycle may help to show if the N availability has been excessive. The higher yields, 13.5 Mg/ha are the same with the lower fertilizer applications, with the lower soil N availabilities and with the lower contents of nitrates in the lower part of the stem (0.4 g NNO3/ kg). All of this show there is ample room to rationalize the nitrogen use

Soil porosity changes in orchards with subsurface irrigation: quantification and interpretation

In order to assess the irrigation efficiency under water-limiting conditions, four different treatments of subsurface irrigation of peach trees in a semi-arid Mediterranean climate near Lleida (NE Iberian Peninsula) were tested. The treatments included pressurized air injection, deficit irrigation, full irrigation (as control) and an addition of rice husk around the pipe to improve porosity. Because the latter treatment improved physical conditions and resulted in better tree growth, a micromorphological study was conducted in order to understand the reason for this behaviour. The experiment was carried out in a commercial peach orchard (Prunus persica L.). The soil was a Xeric Torriorthent, with a loam texture, affected by salinity and with low organic matter content. One undisturbed block (30 cm each side) was taken from each treatment, and two vertical thin sections, 5 × 13 cm, including the subsurface pipe, were made. A fluorescent dye was added to the polyester resin to obtain UV light images of the porosity. The pore parameters and the pore size distribution were obtained for each treatment. Strong changes in the pore types of the four treatments are evident in the thin sections. Full and deficit irrigation treatments are characterised by a weakly developed subangular blocky structure, with a vesicular intra-aggregate structure. Deficit irrigation with air injection produced, in its upper part, a structure similar to the full and deficit irrigation treatments. In the surroundings and below the pipe, where the effect of pressurized air was higher, the soil structure is apedal, with vesicles (bubbles), 200 – 500 µm in size. Porosity of the soil modified with rice husk is greater than that of the other three treatments: the 15 – 30 µm porosity fraction is double, and the larger fractions three times that of the other treatments. It contains many oval excrements of mites (probably Oribatidae), 50 – 100 µm in size, associated with moderately decomposed rice husk tissues. We conclude that the modifications around the irrigation pipes that promoted faunal activity are very effective in conveying water to the soil in comparison to that of pressurized air, which only increases vesicular (non connected) porosity.info:eu-repo/semantics/publishedVersio

Herbivores, saprovores and natural enemies respond differently to within-field plant characteristics of wheat fields

Understanding ecosystem functioning in a farmland context by considering the variety of ecological strategies employed by arthropods is a core challenge in ecology and conservation science. We adopted a functional approach in an assessment of the relationship between three functional plant groups (grasses, broad-leaves and legumes) and the arthropod community in winter wheat fields in a Mediterranean dryland context. We sampled the arthropod community as thoroughly as possible with a combination of suction catching and flight-interception trapping. All specimens were identified to the appropriate taxonomic level (family, genus or species) and classified according to their form of feeding: chewing-herbivores, sucking-herbivores, flower-consumers, omnivores, saprovores, parasitoids or predators. We found, a richer plant community favoured a greater diversity of herbivores and, in turn, a richness of herbivores and saprovores enhanced the communities of their natural enemies, which supports the classical trophic structure hypothesis. Grass cover had a positive effect on sucking-herbivores, saprovores and their natural enemies and is probably due to grasses’ ability to provide, either directly or indirectly, alternative resources or simply by offering better environmental conditions. By including legumes in agroecosystems we can improve the conservation of beneficial arthropods like predators or parasitoids, and enhance the provision of ecosystem services such as natural pest controlPeer ReviewedPostprint (author's final draft

Ti(III) Catalysts for CO2/Epoxide Copolymerization at Unusual Ambient Pressure Conditions

Titanium compounds in low oxidation states are highly reducing species and hence powerful tools for the functionalization of small molecules. However, their potential has not yet been fully realized because harnessing these highly reactive complexes for productive reactivity is generally challenging. Advancing this field, herein we provide a detailed route for the formation of titanium(III) orthophenylendiamido (PDA) species using [LiBHEt3] as a reducing agent. Initially, the corresponding lithium PDA compounds [Li2(ArPDA)(thf)3] (Ar = 2,4,6-trimethylphenyl (MesPDA), 2,6-diisopropylphenyl (iPrPDA)) are combined with [TiCl4(thf)2] to form the heterobimetallic complexes [{TiCl(ArPDA)}(?-ArPDA){Li(thf)n}] (n = 1, Ar = iPr 3 and n = 2, Ar = Mes 4). Compound 4 evolves to species [Ti(MesPDA)2] (6) via thermal treatment. In contrast, the transformation of 3 into [Ti(iPrPDA)2] (5) only occurs in the presence of [LiNMe2], through a lithium-assisted process, as revealed by density functional theory (DFT). Finally, the Ti(IV) compounds 3?6 react with [LiBHEt3] to give rise to the Ti(III) species [Li(thf)4][Ti(ArPDA)2] (Ar = iPr 8, Mes 9). These low-valent compounds in combination with [PPN]Cl (PPN = bis(triphenylphosphine)iminium) are proved to be highly selective catalysts for the copolymerization of CO2 and cyclohexene epoxide. Reactions occur at 1 bar pressure with activity/selectivity levels similar to Salen? Cr(III) compounds.Comunidad de MadridUniversidad de AlcaláPrograma Estímulo a la Investigación de Jóvenes Investigadore

Phase I, first-in-human study of MSC-1 (AZD0171), a humanized anti-leukemia inhibitory factor monoclonal antibody, for advanced solid tumors

Leukemia inhibitory factor; Safety; Solid tumorsFactor inhibidor de la leucemia; Seguridad; Tumores sólidosFactor inhibidor de la leucèmia; Seguretat; Tumors sòlidsBackground Activation of leukemia inhibitory factor (LIF) is linked to an immunosuppressive tumor microenvironment (TME), with a strong association between LIF expression and tumor-associated macrophages (TAMs). MSC-1 (AZD0171) is a humanized monoclonal antibody that binds with high affinity to LIF, promoting antitumor inflammation through TAM modulation and cancer stem cell inhibition, slowing tumor growth. In this phase I, first-in-human, open-label, dose-escalation study, MSC-1 monotherapy was assessed in patients with advanced, unresectable solid tumors. Materials and methods Using accelerated-titration dose escalation followed by a 3 + 3 design, MSC-1 doses of 75-1500 mg were administered intravenously every 3 weeks (Q3W) until progression or unmanageable toxicity. Additional patients were enrolled in selected cohorts to further evaluate safety, pharmacokinetics (PK), and pharmacodynamics after escalation to the next dose had been approved. The primary objective was characterizing safety and determining the recommended phase II dose (RP2D). Evaluating antitumor activity and progression-free survival (PFS) by RECIST v1.1, PK and immunogenicity were secondary objectives. Exploratory objectives included pharmacodynamic effects on circulating LIF and TME immune markers. Results Forty-one patients received treatment. MSC-1 monotherapy was safe and well tolerated at all doses, with no dose-limiting toxicities. The maximum tolerated dose was not reached and the RP2D was determined to be 1500 mg Q3W. Almost half of the patients had treatment-related adverse events (TRAEs), with no apparent trends across doses; no patients withdrew due to TRAEs. There were no objective responses; 23.7% had stable disease for ≥2 consecutive tumor assessments. Median PFS was 5.9 weeks; 23.7% had PFS >16 weeks. On-treatment changes in circulating LIF and TME signal transducers and activators of transcription 3 signaling, M1:M2 macrophage populations, and CD8+ T-cell infiltration were consistent with the hypothesized mechanism of action. Conclusions MSC-1 was very well tolerated across doses, with prolonged PFS in some patients. Biomarker and preclinical data suggest potential synergy with checkpoint inhibitors.This work was supported by Northern Biologics (no grant number). Medical writing support for the development of this manuscript, under the direction of the authors, was provided by Carole Mongin-Bulewski, PhD, of Ashfield MedComms (Manchester, UK), an Ashfield Health company, and was funded by AstraZeneca (no grant number)