1,377 research outputs found

    Percepciones y receptividad de la bancarización de las transacciones en los sectores económicos de la ciudad de Pereira años 2014 - 2018

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    CD-T 332.17 B438;89 p.Aspectos puntuales de la nueva reforma tributaria (Ley 1430 de 2010) -- Percepciones de las reformas tributarias por parte de la población -- Receptividad de la aplicación de la Ley 1430 de 2010 -- Guía práctica de la aplicación del artículo 26 de la Ley 1430 de 2010.Universidad Libre Seccional Pereir

    Creación de marca confecciones TEMPRA

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    77 páginas : ilustraciones, gráficos, fotografíasEI presente trabajo de grado es el resultado académico del desarrollo de la creación de un plan de marketing creado para Confecciones TEMPRA una empresa pyme ubicada en la ciudad de Medellín. La construcción del plan de marketing, dio respuesta a la problemática de la empresa la cual ha crecido de manera significativa sin contar con ninguna herramienta de mercadeo. El trabajo evidencia como respuesta dos planteamientos, el primero la creación de marca para Confecciones TEMPRA una empresa maquiladora con más de 14 años de experiencia en el sector textil, y el segundo construir una estructura de mercadeo para la empresa en la cual se creó un plan de mejoramiento y acondicionamiento a las funciones del nuevo departamento de mercadeoEspecialista en Gerencia de MercadeoEspecializació

    Diálogo de saberes, memorias y territorios

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    La historia reciente de Colombia —sus memorias y sus territorios periféricos— son tema de conversación en esta obra colectiva que compila resultados de investigaciones y reflexiones que se valen del diálogo de saberes como metodología cualitativa para abordar y comprender relatos críticos y urgentes. Cada una de sus cuatro partes es una invitación para el lector: a recrear los saberes, a pensar la relación con el ambiente y el territorio, a reconocer los retratos de la violencia en Colombia y, finalmente, a reflexionar sobre las pedagogías para la paz. Esta es el cuarto libro de la serie Diálogo de saberes en comunicación, la cual tiene el compromiso de promover la construcción colectiva del conocimiento sobre prácticas y procesos de comunicación para el cambio social.https://catalogo.udem.edu.co/dialogo-de-saberes-memorias-y-territorios--sociologia-sociedad-y-cultura.html#.XbcVIegzbc

    Investigación de fenómenos psicosociales

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    The book “Investigación de fenómenos psicosociales”. An approach for the encounter with the other is an initiative of some researchers of the Psychology program of the Manizales Regional Center of the Catholic University Luis Amigó, due to the exponential growth of research in phenomena that shape the social reality of our context and the interest of problematizing research as an option of encounter with people and communities, rethinking traditional and extractivist notions in the construction of knowledge. With this initiative, it is evident that the research processes carried out throughout the years of existence of the Psychology program, have been interlocated, accompanied and fed back by academic agents from other institutions, which has significantly nurtured the discussions. In addition, the production presents a common denominator, and that is qualitative research, as a recurrent design in the different studies, becoming a device for the problematization of the text.illustratorEl libro Investigación de fenómenos psicosociales. Una aproximación para el encuentro con el otro es una iniciativa de algunos investigadores del programa de Psicología del Centro Regional Manizales de la Universidad Católica Luis Amigó, en virtud del crecimiento exponencial de la investigación en fenómenos que configuran la realidad social de nuestro contexto y el interés de problematizar la investigación como una opción de encuentro con personas y comunidades, replanteando nociones tradicionales y extractivistas en la construcción de conocimiento. Con esta iniciativa se evidencia que los procesos de investigación realizados a través de los años de existencia del programa de Psicología, se han visto interlocutados, acompañados y retroalimentados por agentes académicos de otras instituciones, lo que ha nutrido significativamente las discusiones. Además, la producción presenta un común denominador, y es la investigación cualitativa, como diseño recurrente en los diferentes estudios, convirtiéndose en un dispositivo para la problematización del texto

    Impact of preemptive hospitalization on health outcomes at the temporary COVID-19 hospital in Mexico City: a prospective observational study.

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    INTRODUCTION: In response to the evolution of the coronavirus disease 2019 (COVID-19) pandemic, the admission protocol for the temporary COVID-19 hospital in Mexico City has been updated to hospitalize patients preemptively with an oxygen saturation (SpO2) of >90%. METHODS: This prospective, observational, single-center study compared the progression and outcomes of patients who were preemptively hospitalized versus those who were hospitalized based on an SpO2 ⩽90%. We recorded patient demographics, clinical characteristics, COVID-19 symptoms, and oxygen requirement at admission. We calculated the risk of disease progression and the benefit of preemptive hospitalization, stratified by CALL Score: age, lymphocyte count, and lactate dehydrogenase (<8 and ⩾8) at admission. RESULTS: Preemptive hospitalization significantly reduced the requirement for oxygen therapy (odds ratio 0.45, 95% confidence interval 0.31-0.66), admission to the intensive care unit (ICU) (0.37, 0.23-0.60), requirement for invasive mechanical ventilation (IMV) (0.40, 0.25-0.64), and mortality (0.22, 0.10-0.50). Stratification by CALL score at admission showed that the benefit of preemptive hospitalization remained significant for patients requiring oxygen therapy (0.51, 0.31-0.83), admission to the ICU (0.48, 0.27-0.86), and IMV (0.51, 0.28-0.92). Mortality risk remained significantly reduced (0.19, 0.07-0.48). CONCLUSION: Preemptive hospitalization reduced the rate of disease progression and may be beneficial for improving COVID-19 patient outcomes

    Fifth European Dirofilaria and Angiostrongylus Days (FiEDAD) 2016

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    CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

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    Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality
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