Isolated photon production in pppp collisions at forward rapidities and high multiplicity events

The production of isolated photons in high multiplicity events is investigated considering the Color Glass Condensate (CGC) formalism. The associated cross-section for proton - proton collisions is estimated considering three distinct solutions of the Balitsky - Kovchegov (BK) equation and predictions for the normalized photon yield as a function of the multiplicities of co - produced charged particles are presented. We predict the increasing of the yield with the multiplicity, with the slope being smaller for larger rapidities. As the isolated photon production is not affected by the fragmentation process, a future experimental investigation of this process in current high energy hadronic colliders is ideal to test the treatment of high multiplicity events using the CGC formalism, previously applied only for the production of hadronic final states.Comment: 9 pages, 6 figures. Improved version published in European Physical Journal

Emissions Reporting Maturity Model: supporting cities to leverage emissions-related processes through performance indicators and artificial intelligence

Climate change and global warming have been trending topics worldwide since the Eco-92 conference. However, little progress has been made in reducing greenhouse gases (GHGs). The problems and challenges related to emissions are complex and require a concerted and comprehensive effort to address them. Emissions reporting is a critical component of GHG reduction policy and is therefore the focus of this work. The main goal of this work is two-fold: (i) to propose an emission reporting evaluation model to leverage emissions reporting overall quality and (ii) to use artificial intelligence (AI) to support the initiatives that improve emissions reporting. Thus, this work presents an Emissions Reporting Maturity Model (ERMM) for examining, clustering, and analysing data from emissions reporting initiatives to help the cities to deal with climate change and global warming challenges. The Performance Indicator Development Process (PIDP) proposed in this work provides ways to leverage the quality of the available data necessary for the execution of the evaluations identified by the ERMM. Hence, the PIDP supports the preparation of the data from emissions-related databases, the classification of the data according to similarities highlighted by different clustering techniques, and the identification of performance indicator candidates, which are strengthened by a qualitative analysis of selected data samples. Thus, the main goal of ERRM is to evaluate and classify the cities regarding the emission reporting processes, pointing out the drawbacks and challenges faced by other cities from different contexts, and at the end to help them to leverage the underlying emissions-related processes and emissions mitigation initiatives

Glycosylation with O-linked β-N-acetylglucosamine (O-GlcNAc) induces vascular dysfunction via production of superoxide anion/reactive oxygen species

Overproduction of superoxide anion (•O2-) and O-linked β-N-acetylglucosamine (O-GlcNAc)-modification in the vascular system are contributors to endothelial dysfunction. This study tested the hypothesis that increased levels of O-GlcNAc-modified proteins contribute to •O2- production via activation of NADPH oxidase, resulting in impaired vasodilation. Rat aortic segments and vascular smooth muscle cell (VSMCs) were incubated with vehicle (methanol) or PUGNAc (100 µM). PUGNAc produced a time-dependent increase in O-GlcNAc levels in VSMC and decreased endothelium-dependent relaxation, which was prevented by apocynin and Tiron, suggesting that •O2- contributes to endothelial dysfunction under augmented O-GlcNAc levels. Aortic segments incubated with PUGNAc also exhibited increased levels of ROS, assessed by dihydroethidium fluorescence, and augmented •O2- production, determined by lucigenin-enhanced chemiluminescence. Additionally, PUGNAc treatment increased Nox1 and Nox4 protein expression in aorta and VSMCs. Translocation of p47phox subunit from the cytosol to the membrane was greater in aortas incubated with PUGNAc. VSMCs displayed increased p22phox protein expression after PUGNAc incubation, suggesting that NADPH oxidase is activated in conditions where O-GlcNAc protein levels are increased. In conclusion, O-GlcNAc levels reduce endothelium-dependent relaxation by overproduction of •O2- via activation of NADPH oxidase. This may represent an additional mechanism by which augmented O-GlcNAc levels impair vascular function

Adsorptive potential of Zn–Al and Mg–Fe layered double hydroxides for the removal of 2–nitrophenol from aqueous solutions

Two layered double hydroxides (LDH) of the type Zn–Al and Mg–Fe were synthesized, characterized and used as adsorbents to uptake 2–nitrophenol (2–NP) from aqueous solutions. XRD, FTIR, SEM, EDS, AFM and N2 adsorption/desorption curves were used to characterize the Zn–Al–LDH and Mg–Fe–LDH. The potential of both layered double hydroxides to adsorb 2–NP was investigated by adsorption kinetics, equilibrium, thermodynamics and consecutive adsorption/desorption cycles. The characterization indicated a high crystallinity degree and a well–organized and lamellar structure, confirming the efficiency of the synthesis. Elovich was the better kinetic model to describe the 2–NP adsorption onto Zn–Al–LDH, while Pseudo–second order was the best for Mg–Fe–LDH. For both LDHs, the adsorption equilibrium followed the Freundlich model. The process was endothermic, being the maximum adsorption capacities of 290 and 165 mg g–1 for Zn–Al–LDH and Mg–Fe–LDH, respectively. LDHs can be applied for five adsorption/desorption cycles with excellent adsorption capacities. It can be concluded that Zn–Al–LDH and Mg–Fe–LDH are promising materials to treat waters and wastewaters containing 2–nitropheno

ALTERAÇÃO DE PARÂMETROS RELACIONADOS AO RISCO CARDIOVASCULAR EM ADOLESCENTES OBESOS

Introdução: A obesidade juvenil é considerada um problema de saúde pública e o aumento de sobrepeso e obesidade nesta fase está associado a complicações metabólicas e cardiovasculares na idade adulta1. Objetivo: Identificar alterações nos parâmetros antropométricos e bioquímicas em adolescentes obesos. Metodologia: Adolescentes (14-18 anos), de ambos os sexos, matriculados em escolas de Ensino Médio de Barra do Garças – MT foram divididos em grupos experimentais de acordo com o Índice de Massa corporal (IMC): eutróficos (IMC ˃18 e ˂25) e obesos (IMC˂25)2. O IMC, circunferência abdominal, porcentagem de gordura corporal, pressão arterial, dosagens de colesterol total, triglicérides e glicemia foram avaliados em ambos grupos. Diferenças estatísticas foram calculadas através do teste T Student, (p˂0,05). Resultados e discussões: Foram avaliados 89 adolescentes, sendo 74 eutróficos e 15 obesos. Os adolescentes obesos apresentaram aumento dos valores de pressão sistólica [(mmHg) 126 ± 3,7 vs. 116±1,7], circunferência abdominal [(cm) 87± 1,9 vs. 72 ± 0,6], porcentagem de gordura corporal [(%) 27±1,8 vs. 18 ± 0,7], IMC (27,1±0,7 vs. 21.0±0,2), quando comparados ao grupo eutrófico. Adicionalmente, os adolescentes obesos apresentaram aumento nos índices de colesterol total [(mg/dL) 160 ± 7,4 vs. 140 ± 3,8], triglicérides [(mg/dL) 106,6±14,4 vs. 64,0±3,8], se comparados ao grupo eutrófico. Tanto a pressão diastólica quanto os níveis glicêmicos não apresentaram alteração entre os grupos. Conclusões: As alterações de parâmetros antropométricos e bioquímicos observados em adolescentes obesos demonstram que fatores de risco para doenças cardiovasculares estão alterados nessa população jovem, favorecendo o surgimento precoce de doenças crônicas como Diabetes Mellitus e da hipertensão arterial

Evaluation of Intensivist-Nurses’ Knowledge Concerning Medication Administration Through Nasogastric and Enteral Tubes

This study evaluates the knowledge of nurses working in intensive care units concerning recommendations for the proper administration of medication through nasogastric and enteral tubes. This exploratory-descriptive study with a quantitative approach was carried out with 49 nurses in an intensive care unit of a tertiary hospital in Fortaleza, CE, Brazil. A total of 36.7% of nurses reported they disregard the dosage forms provided by the pharmacy at the time of administering the medication through tubes. Metal, wood, or a plastic mortar is the method most frequently reported (42.86%) for crushing prescribed solid forms; 32.65% leave the drugs in 20ml of water until dissolved; 65.3% place the responsibility for choosing the pharmaceutical formulation and its correlation with the tube site, either into the stomach or into the intestine, on the physician. The results indicate there is a gap between specific literature on medication administered through tubes and knowledge of nurses on the subject.El objetivo del estudio fue evaluar los conocimientos del enfermero de la unidad de cuidados intensivos sobre las recomendaciones para la correcta administración de medicamentos por sonda nasogástrica y nasoentérica. Se trata de un estudio exploratorio-descriptivo y cuantitativo con 49 enfermeros en una unidad de cuidados intensivos de un hospital terciario, en la ciudad de Fortaleza, estado de Ceará, Brasil. 36,7% no prestan atención a las formas disponibles en el sector de farmacia en el momento de su utilización por sonda. El pilón de metal, madera o plástico fue el método más citado (42,86%) para triturar las formas sólidas prescritas. 32,65% dejan los fármacos en 20mL de agua hasta que se disuelvan. 65,3% atribuyen al médico la responsabilidad de decidir sobre la formulación y la correlación con la ubicación de la sonda en el tracto gastrointestinal. Los resultados indican que hay una diferencia entre la literatura para los medicamentos administrados por sonda y el conocimiento de los enfermeros sobre el tema.O estudo objetivou avaliar o conhecimento do enfermeiro de unidade de terapia intensiva sobre as recomendações para a correta administração de medicamentos, por sondas nasogástrica e nasoenteral. Estudo exploratório-descritivo, com abordagem quantitativa, realizado com 49 enfermeiros em uma unidade de terapia intensiva de um hospital terciário, localizado na cidade de Fortaleza, no Estado do Ceará, Brasil. Dos enfermeiros, 36,7% relataram não dar atenção às formas farmacêuticas disponibilizadas pelo setor de farmácia na hora da utilização por sonda. O pilão de metal, madeira ou plástico foi o método mais referido (42,86%) para triturar as formas sólidas prescritas. Sendo que 32,65% costuma deixar os fármacos em 20mL de água até dissolver, 65,3% atribuem ao médico a responsabilidade sobre a decisão da formulação farmacêutica e a correlação com a localização da sonda no trato gastrointestinal. Os achados apontam para diferença entre a literatura específica para medicamentos administrados por sonda e o conhecimento de enfermeiros sobre o assunto