Tick-tock : a pressão do tempo social sobre as diferenças individuais

Orientador : Fernando Mazzilli LouzadaTrabalho de Conclusão de Curso (Bacharelado) - Universidade Federal do Paraná. Setor de Ciências Biológicas. Curso de Graduação em Biomedicina

Characterization of drug poisonings registered in a toxicological information center of Piauí from 2007 to 2012

Objective: To characterize the profile of drug poisoning reported in a Toxicological Information Center of Piauí in the period from 2007 to 2012. Method: Data were collected through questionnaires of the National Poisoning Information System, through the analysis of the records of drug intoxication reported in the period 2007-2012 by the Toxicological Information Center of Piauí and were analyzed using the programs Microsoft Excel 2007 and GraphPad Prism 5. Results: There were 503 drug poisonings, which were more frequent in females, children and young adults in urban areas. Individual accidents and suicide attempts were the mains causes and benzodiazepines were the most common drugs. Conclusion: The data found in this study are consistent with results from other Brazilian studies onthe subject

Assistência de enfermagem à criança autista: revisão integrativa

Introduction: The Autistic Spectrum Disorder (ASD) configures a neurodevelopmental disorder that involves social interaction, communication and behavior identified generally in pre-school children. The nursing professionals must perform the management and monitoring of the autistic child.Objective: To examine the scientific evidence about nursing care to the autistic child.Methodology: An integrative review of the literature, held in databases: CINAHL, Web of Science and LILACS databases using the search terms: “Nursing Care”, “Child”, “Child, Preschool”, “Autistic Disorder” and “Autism Spectrum Disorder”. There were included articles published between the period of 2013 to 2017 in Portuguese, Spanish and English.Resulted: The articles included were presented in summary table and the analysis of the results was performed descriptively presenting the synthesis of studies through comparisons and highlight of differences and/or similarities. It was identified that is basic to nursing to have empathy, holistic vision and knowledge to perform singular assistance and of quality for the child and family.Conclusion: Nursing uses the empathy, holistic view and different strategies for the care to the autistic child; however, the professionals refer difficulties in clinical practice. The publications on the subject are scarce being necessary the development of clinical research.  Introducción: El Trastorno del Espectro Autista (TEA) configura un trastorno del neurodesarrollo que compromete la interacción social, comunicación y comportamiento, identificado generalmente, en el niño preescolar. Los profesionales de enfermería deben realizar el manejo y acompañamiento del niño autista.Objetivo: Analizar las evidencias científicas sobre la asistencia de Enfermería al niño autista.Metodología: Revisión integradora de la literatura realizada en la base de datos: CINAHL, Web of Science e LILACS, se utilizó como descriptores: Nursing Care/Cuidados de Enfermagem”, “Child/Criança”, “Child, Preschool/Pré-escolar”, “Autism Disorder/Transtorno Autístico” y “Autism Spectrum Disorder/Transtorno do Espectro Autista”. Se incluyeron artículos publicados entre el período de 2013 a 2017 en portugués, español e inglés.Resultados: Los artículos incluidos fueron presentados en cuadro sinóptico y el análisis de los resultados fue realizado de forma descriptiva presentando la síntesis de los estudios por medio de comparaciones y destaque de diferencias y / o semejanzas. Se identificó que es fundamental que la enfermería tenga empatía, visión holística y conocimiento para realizar asistencia singular y de calidad para el niño y la familia.Conclusión: La enfermería utiliza la empatía, visión holística y diferentes estrategias para el cuidado del niño autista, sin embargo, los profesionales refieren dificultades en la práctica clínica. Las publicaciones sobre la temática son escasas siendo necesario el desarrollo de investigaciones clínicas.Introdução: O Transtorno do Espectro Autista (TEA) configura uma perturbação do neurodesenvolvimento que compromete a interação social, comunicação e comportamento identificado geralmente na criança pré-escolar. Os profissionais de enfermagem devem realizar o manejo e acompanhamento da criança autista. Objetivo: Analisar as evidências científicas sobre a assistência de Enfermagem à criança autista.Metodologia: Revisão integrativa da literatura, realizada nas bases de dados: CINAHL, Web of Science e LILACS utilizando os termos de busca: “Nursing Care/Cuidados de Enfermagem”, “Child/Criança”, “Child, Preschool/Pré-escolar”, “Autism Disorder/Transtorno Autístico” e “Autism Spectrum Disorder/Transtorno do Espectro Autista”. Foram incluídos artigos publicados entre o período de 2013 a 2017 nos idiomas português, espanhol e inglês.Resultados: Os artigos incluídos foram apresentados em quadro sinóptico e a análise dos resultados foi realizada de forma descritiva apresentando a síntese dos estudos por meio de comparações e destaque de diferenças e/ou semelhanças. Identificou-se que é fundamental à enfermagem ter empatia, visão holística e conhecimento para realizar assistência singular e de qualidade para a criança e família. Conclusão: A enfermagem utiliza a empatia, visão holística e diferentes estratégias para o cuidado a criança autista, no entanto os profissionais referem dificuldades na pratica clínica. As publicações sobre a temática são escassas sendo necessário o desenvolvimento de pesquisas clínicas

Experiences of motherhood in university students in Brazil: a qualitative study

Introduction: The women’s rise to higher education contrasts with the phenomenon of motherhood, since it instigates changes in various contexts, whether physiological or emotional, and directly affects the way of life and routine of those women, resulting in a constant conflict between motherhood and academic career. In this sense, the student has to restructure responsibilities and behaviors, as well as requires family support and laws that support her in this period. Objectives: To describe the experiences of motherhood in university students, and to identify the strategies developed by university students to adapt motherhood with academic routine. Methods: This is a descriptive, exploratory and qualitative research carried out in a private University Center in Brazil. The participants were ten Nursing undergraduate students, regularly enrolled and who experienced motherhood during the academic term. Data were collected during August and September 2019, through a recorded interview using a semi-structured form. For the treatment and analysis of the data, the Collective Subject Discourse was used. The study followed the ethical precepts and was approved by the ethics committee (opinion n. 3.419.572). Results: The participants’ discourses gave rise to four central ideas: Feelings experienced from the discovery of pregnancy; The discovery of pregnancy and the decision to continue the course; Support relationships as a decisive factor for the non-abandonment of the course and Strategies to reconcile motherhood with academic routine. The main key expressions identified in the discourses were: joy, fear, insecurity, anguish, concern, distress, anger, sadness, interrupting, giving up, taking time off from the course, not taking time off from the course, family support, support from friends, support from the institution, adjusting schedules, studying while my child sleeps, family help, taking the baby to college, storing milk while breastfeeding. Conclusion: The analysis of the discourses revealed that the experience of motherhood in the university sphere is marked by a combination of different feelings, and by an important process of adaptations to the new moment, since there is a reflection and indecision about the continuity of the academic trajectory. The reports also highlight the importance of family, institutional and friend support, such as a support network of incentive to the care with the child, as well as the use of strategies to reconcile academic routine with motherhood.info:eu-repo/semantics/publishedVersio

Violência doméstica contra a criança sob a ótica de estudantes de graduação em enfermagem

Aim: to verify the knowledge of undergraduate nursing students regarding domestic violence against children. Method: it is a descriptive-exploratory study with a qualitative approach, carried out with 20 undergraduate nursing students. The semi-structured interview and the content analysis technique have been used for data collection. Results: domestic violence against children is practiced by the people who are closest to the family; the human rights are violated, directly affecting children’s growth and development; the most well-known forms of violence are physical, verbal, psychological, sexual in addition to negligence. Final considerations: discussions about domestic violence against children are important in the professional training, considering the articulation of theory and practice for the construction of learning, and the development of skills and abilities of the future nurses in order to face this problem.Objetivo: verificar el conocimiento de estudiantes de graduación en enfermería sobre la violencia doméstica contra los niños. Método: estudio cualitativo de perspectiva descriptivo-exploratorio, realizada con 20 estudiantes de un curso de graduación en enfermería. Se utilizó la entrevista semiestructurada para recolección de datos y para análisis la técnica de análisis contenido. Resultados: se identificó que la violencia doméstica contra los niños parte de las personas más cercanas del convivio familiar, en que los derechos humanos son violados, afectando directamente su crecimiento y desarrollo; y las formas más conocidas son las violencias: física, verbal, psicológica, sexual y la negligencia. Consideraciones finales: discusiones sobre la violencia doméstica contra los niños son importantes en la formación profesional, pensando en la articulación de la teoría y práctica para construcción del aprendizaje y desarrollo de competencias y habilidades de los futuros enfermeros para el enfrentamiento de ese tipo de violencia.Objetivo: averiguar o conhecimento de estudantes de graduação em enfermagem sobre a violência doméstica contra a criança. Método: estudo de abordagem qualitativa do tipo descritivo-exploratória, realizada com 20 estudantes do curso de graduação em enfermagem. Utilizou-se da entrevista semiestruturada para coleta de dados e para análise dos dados a técnica de análise conteúdo. Resultados: a violência doméstica contra as crianças parte de pessoas mais próximas do convívio familiar, em que os direitos humanos dessas crianças são violados, afetando diretamente no seu crescimento e desenvolvimento; sendo que as formas mais conhecidas são as violências: física, verbal, psicológica, sexual e a negligência. Considerações finais: discussões sobre a violência doméstica contra a criança são importantes na formação profissional, pensando na articulação da teoria e prática para a construção da aprendizagem e desenvolvimento de competências e habilidades dos futuros enfermeiros para o enfrentamento desse agravo

Energy metabolism: gluconeogenesis and oxidative phosphorylation

Most animal cells are able to meet their energy needs from the oxidation of various types of compounds: sugars, fatty acids, amino acids, but some tissues and cells of our body depend exclusively on glucose and the brain is the largest consumer of all. That is why the body has mechanisms in order to keep glucose levels stable. As it decreases, the degradation of hepatic glycogen occurs, which maintains the appropriate levels of blood glucose allowing its capture continues by those tissues, even in times of absence of food intake. But this reserve is limited, so another metabolic pathway is triggered for glucose production, which occurs in the kidneys and liver and is called gluconeogenesis, which means the synthesis of glucose from non-glucose compounds such as amino acids, lactate, and glycerol. Most stages of glycolysis use the same enzymes as glycolysis, but it makes the opposite sense and differs in three stages or also called deviations: the first is the conversion of pyruvate to oxaloacetate and oxaloacetate to phosphoenolpyruvate. The second deviation is the conversion of fructose 1,6 biphosphate to fructose 6 phosphate and the third and last deviation is the conversion of glucose 6 phosphate to glucose

Association between light exposure and metabolic syndrome in a rural Brazilian town

Context: Metabolic syndrome (MetS) is a complex condition comprising a ‘clustering’ of components representing cardiometabolic risk factors for heart disease and diabetes; its prevalence rate is high and consequences serious. Evidence suggests that light exposure patterns and misalignment of circadian rhythms might contribute to MetS etiology by impacting energy metabolism and glucose regulation. Objective: We hypothesised that individuals with MetS would show disrupted circadian and sleep parameters alongside differences in light exposure profiles. We investigated this using data from a cohort study in Brazil. Methods: Data from 103 individuals from the Baependi Heart Cohort Study aged between 50 and 70 were analysed. Motor activity and light exposure were measured using wrist-worn actigraphy devices. Cardiometabolic data were used to calculate the number of MetS components present in each participant, and participants grouped as MetS/non-MetS according to standard guidelines. Between-group comparisons were made for the actigraphy measures; additionally, correlation analyses were conducted. Results: Motor activity and circadian profiles showed no differences between groups. However, the MetS group presented lower light exposure during the day and higher light exposure at night. Correlation analyses, including all participants, showed that greater daytime light exposure and greater light exposure difference between day and night were associated with reduced MetS risk (a lower number of MetS components). Also, the light exposure difference between day and night correlated with body mass index across all participants. Conclusions: The observed results suggest a direct association between light exposure and MetS which appears to not be attributable to disruptions in circadian activity rhythm nor to sleep parameters. This link between light exposure patterns and MetS risk could inform possible prevention strategies

Anti-inflammatory foods: human food patterns, bioactive principles and mechanisms of action

With the increase in life expectancy accompanied by the gradual decrease in the birth rate as well as the greater income distribution associated with the quantitative increase in the minimum wage above inflation and the increase in its purchasing power, today the Brazilian population shows a moment exactly opposite to that found in the last century both in epidemiological terms and in the nutritional pattern. Brazil is currently experiencing the same pattern of mortality as developed countries: the majority of chronic non-communicable diseases are the main cause of death associated with an established model of obesity and sedentarism. These factors incline the scientific community and health professionals to turn their efforts to find food solutions that ease this epidemiological picture and it is in this context that anti-inflammatory foods have gained prominence. The following describes the main compounds that fit this magnitude of effect and their mechanisms of action

COVID-19: ANÁLISE DE CASOS CONFIRMADOS EM TERESINA, PIAUI, BRASIL

Introduction: Coronavirus are microorganisms responsible for causing respiratory infections that can vary from asymptomatic to severe. The spread of the virus around the world has led to a pandemic position, which has claimed numerous victims. Given the magnitude of the problem, the study aims to analyze the epidemiological profile of confirmed cases of COVID-19 in Teresina-PI. Design: Descriptive and epidemiological study. The study population consisted of 315 confirmed cases of Covid-19, in individuals residing in the city of Teresina-PI, between March and April 2020. The variables evaluated were: age group, sex, deaths confirmed by Covid- 19 and confirmed cases of Covid-19 by area of ​​the city. Results: There was a predominance of confirmed cases of Covid-19 in young, female individuals living in an urban area of ​​Teresina. Most deaths occurred in the elderly, being more prevalent in males. Implications: The epidemiological monitoring of cases strengthens the need to implement preventive measures, such as social containment. In addition, the expansion of testing in the population is important in order to identify asymptomatic cases and, consequently, to prevent the spread of the coronavirus, considering that these cases favor the transmission chain.Introdução: Os coronavírus são microrganismos responsáveis por causar infecções respiratória que podem variar de quadros assintomáticos a graves. A disseminação do vírus pelo o mundo conduziu para uma posição de pandemia, a qual tem somado inúmeras vítimas. Mediante a magnitude da problemática, o estudo tem como objetivo analisar o perfil epidemiológico dos casos confirmados de COVID-19 em Teresina-PI. Delineamento: Estudo descritivo e epidemiológico. A população do estudo foi composta por 315 casos confirmados de Covid-19, em indivíduos residentes na cidade de Teresina-PI, no período entre de março e abril de 2020. As variáveis avaliadas foram: faixa etária, sexo, óbitos confirmados por Covid-19 e casos confirmados de Covid-19 por área da cidade. Resultados: Observou-se a predominância de casos confirmados de Covid-19 em indivíduos jovens, do sexo feminino e que residem em área urbana de Teresina. A maioria dos óbitos ocorreu em idosos, sendo mais predominantes em indivíduos do sexo masculino. Implicações: O monitoramento epidemiológico dos casos fortalece a necessidade da implementação de medidas preventivas, como a contenção social. Somado a isso, a ampliação da testagem na população é importante, a fim de identificar casos assintomáticos e, consequentemente, evitar a disseminação do coronavírus, tendo em vista que esses casos favorecem a cadeia de transmissão