Comparison of thyroglobulin concentrations measured by two immunoradiometric assay

© 2020, University of Kragujevac, Faculty of Science. All rights reserved. Circulating thyroglobulin measurements is a highly specific test in the management of patients affected by differentiated thyroid cancer after total thyroidectomy, followed by radioiodine ablation. The aim of our study was to com-pare two thyroglobulinimmunoradiometric assays (INEP, Serbia and Cisbio Bioassays, France). Study included 42 patients of both genders with DTC. The subjects were on suppres¬sive doses of levothyroxine and followed up. Results showed concordance between the two assay methods for determining serum thyroglobulin for 39 (92.85%) pa-tients. Statistical analysis showed that there was a direct correlation between two IRMA tests, with a positive correlation coefficient r=0.613 (p 0.05). We concluded that there is good agreement between the two thyroglobulin assays compared in this study

Community Development for Health Promotion

Development of a healthy community today represents an important process from different stand point, especially for improvement of population health and for health promotion intervention among vulnerable population groups such as women and children, adolescents, poor people and refugees. Community orientated approach particularly ensures proper identification and meeting the needs of underserved population groups which are most often not recognised among under, either because they belong to special ethnical or cultural groups or to groups of poor. Community strengthening for improvement of their health is realised through the wide and sustainable partnership of local community members, their leaders, supportive organisations, financers and governmental institutions, which is present in all phases of health promotion intervention. Examples of community based health promotion programmes, in world and in Serbia, show that wide partnership ensures improvement of numerous health determinants which is impossible to achieve by isolated health service activities. Authentic community leaders that are educated for successful leadership during all phases have prominence in development of these programmes. Achievement of their long-term sustainability through the multidisciplinary approach is a constant challenge to community based health promotion programmes

Synthetic, Crystallographic, and Computational Study of Copper(II) Complexes of Ethylenediaminetetracarboxylate Ligands

Copper(II) complexes of hexadentate ethylenediaminetetracarboxylic acid type ligands H4eda3p and H4eddadp (H4eda3p = ethylenediamine-N-acetic-N,N′,N′-tri-3-propionic acid; H4eddadp = ethylenediamine-N,N′-diacetic-N,N′-di-3-propionic acid) have been prepared. An octahedral trans(O6) geometry (two propionate ligands coordinated in axial positions) has been established crystallographically for the Ba[Cu(eda3p)]·8H2O compound, while Ba[Cu(eddadp)]·8H2O is proposed to adopt a trans(O5) geometry (two axial acetates) on the basis of density functional theory calculations and comparisons of IR and UV−vis spectral data. Experimental and computed structural data correlating similar copper(II) chelate complexes have been used to better understand the isomerism and departure from regular octahedral geometry within the series. The in-plane O−Cu−N chelate angles show the smallest deviation from the ideal octahedral value of 90°, and hence the lowest strain, for the eddadp complex with two equatorial β-propionate rings. A linear dependence between tetragonality and the number of five-membered rings has been established. A natural bonding orbital analysis of the series of complexes is also presented.

Community Development for Health Promotion

Development of a healthy community today represents an important process from different stand point, especially for improvement of population health and for health promotion intervention among vulnerable population groups such as women and children, adolescents, poor people and refugees. Community orientated approach particularly ensures proper identification and meeting the needs of underserved population groups which are most often not recognised among under, either because they belong to special ethnical or cultural groups or to groups of poor. Community strengthening for improvement of their health is realised through the wide and sustainable partnership of local community members, their leaders, supportive organisations, financers and governmental institutions, which is present in all phases of health promotion intervention. Examples of community based health promotion programmes, in world and in Serbia, show that wide partnership ensures improvement of numerous health determinants which is impossible to achieve by isolated health service activities. Authentic community leaders that are educated for successful leadership during all phases have prominence in development of these programmes. Achievement of their long-term sustainability through the multidisciplinary approach is a constant challenge to community based health promotion programmes

Assessment of the training needs and interests among directors of health care services in the Kyrgyz Republic

Aim: An assessment of the training needs and interests of health managers working in the health care facilities of the Kyrgyz Republic was conducted, aiming to tailor and shape future training interventions. Methods: A rapid assessment was organized among directors of health care services in the Kyrgyz Republic, using a web-based questionnaire. Due to the pandemic situation (COVID-19), it was impossible to involve all healthcare facilities as initially planned. Therefore, a convenient sample of 75 directors was drawn with a response rate of 77.3%, or 58 filled-in questionnaires. Results: Among respondents, 60.3% were female and 39.7% male managers, with an average age of 53.5 years. Most of the respondents (89.7%) came to a managerial position by direct appointment, while only 10.3% were appointed through competitive process. More than half of health managers (63.8%) do not have any managerial category, and only 25.7% indicated that they have membership in the Association of Health Administrators of Kyrgyzstan[1]. All respondents reported the need to develop computer skills. Discussion: There is a high demand in all aspects of the management of health organizations. The respondents are deciding about involvement in management training based on (a) the full range of training' topics, (b) the quality of the training content, and (c) the focus on developing practical skills. The most cited training needs are digital health (E-Health), financing management, planning, and quality control; the interest in distance learning courses is excellent. Almost two-thirds of managers reported that the Ministry of Health and Social Development (MOHSD KR) did not evaluate their work. Conclusion: The main implications derived from this assessment are related to the culture of lifelong learning among the population of Kyrgyz health managers.   Authors’ contributions: All authors contributed equally.   Conflict of interest: None declared.   Source of funding: The project is financed by the Government of Switzerland. The opinions expressed in this publication are the views of the authors and do not necessarily reflect the opinion of the Government of Switzerland

Assessment of the training needs and interests among directors of health care services in the Kyrgyz Republic

Aim: An assessment of the training needs and interests of health managers working in the health care facilities of the Kyrgyz Republic was conducted, aiming to tailor and shape future training interventions. Methods: A rapid assessment was organized among directors of health care services in the Kyrgyz Republic, using a web-based questionnaire. Due to the pandemic situation (COVID-19), it was impossible to involve all healthcare facilities as initially planned. Therefore, a convenient sample of 75 directors was drawn with a response rate of 77.3%, or 58 filled-in questionnaires. Results: Among respondents, 60.3% were female and 39.7% male managers, with an average age of 53.5 years. Most of the respondents (89.7%) came to a managerial position by direct appointment, while only 10.3% were appointed through competitive process. More than half of health managers (63.8%) do not have any managerial category, and only 25.7% indicated that they have membership in the Association of Health Administrators of Kyrgyzstan[1]. All respondents reported the need to develop computer skills. Discussion: There is a high demand in all aspects of the management of health organizations. The respondents are deciding about involvement in management training based on (a) the full range of training' topics, (b) the quality of the training content, and (c) the focus on developing practical skills. The most cited training needs are digital health (E-Health), financing management, planning, and quality control; the interest in distance learning courses is excellent. Almost two-thirds of managers reported that the Ministry of Health and Social Development (MOHSD KR) did not evaluate their work. Conclusion: The main implications derived from this assessment are related to the culture of lifelong learning among the population of Kyrgyz health managers

The European Registered Toxicologist (ERT) : Current status and prospects for advancement

Acknowledgements We would like to thank the participants of the five workshops in which the issues presented in this paper were discussed and the revised guidelines prepared, as well as the EUROTOX Executive Committee and the societies of toxicology of Sweden, the Netherlands, Switzerland, Austria and France for their support which allowed the workshops to take place.Peer reviewedPostprin

Comparison of Thyroglobulin Concentrations Measured by Two Immunoradiometric Assay

Circulating thyroglobulin measurements is a highly specific test in the management of patients affected by differentiated thyroid cancer after total thyroidectomy, followed by radioiodine ablation. The aim of our study was to compare two thyroglobulinimmunoradiometric assays (INEP, Serbia and Cisbio Bioassays, France). Study included 42 patients of both genders with DTC. The subjects were on suppres¬sive doses of levothyroxine and followed up. Results showed concordance between the two assay methods for determining serum thyroglobulin for 39 (92.85%) patients. Statistical analysis showed that there was a direct correlation between two IRMA tests, with a positive correlation coefficient r=0.613 (p 0.05). We concluded that there is good agreement between the two thyroglobulin assays compared in this study