Government Policies and Sex Work Realities::Human Trafficking in the Regulated Sex Industry

Kleemans, E.R. [Promotor]Gestel, B. van [Copromotor

Electronic and spatial characteristics of the retinylidene chromophore in rhodopsin

The G protein coupled receptor rhodopsin was characterised by physical chemical methods like solid-state NMR, FTIR and UV/Vis spectroscopy. Goal of the research was to determine the impact of steric and electronic properties of the retinal ligand on the rate and efficiency of the photochemical reaction of this light activated receptor. First the required 13C labelled and chemically modified retinal derivatives were obtained by chemical synthesis. Subsequently, solid-state 13C NMR was used as a tool to characterise the electronic structure of the native ligand bound to rhodopsin, while FTIR difference spectroscopy was applied to determine the effect retinal ligands that were modified in the isomerisation region. It transpires that the combined approach of synthesis and spectroscopic techniques can reveal fundamental aspects of the interplay of the electronic properties and the spatial arrangement of the ligand that may ultimately allow a more profound understanding of the activation of GPCRs, in addition to knowledge about the ultrafast and efficient isomerisation of the retinylidene chromophore in rhodopsinUBL - phd migration 201

Product data of tomatoes

In deze produktinformatie: botanische gegevens, geschiedenis, rassen, ziekten en gebreken, samenstelling en energetische waarde, fysische en fysiologische gegevens, consumptie, oogst, transport en verpakking, bewaring en opslag, kwaliteit en sortering, kleinverpakking, industriele verwerkin

Online management of text production from pictures:a comparison between fifth graders and undergraduate students

This study was designed to enhance our understanding of the online management of writing processes by two groups of writers with a different level of expertise, and to explore the impact of this online management on text quality. To this aim, fifth graders (mean age 10.5 years) and undergraduate students (mean age 22.6 years) were asked to compose a narrative from a visual source of images, while their handwriting activity and eye movements were recorded by means of Eye & Pen software and a digitizing tablet. Results showed that fifth graders and undergraduate students used different strategies to engage in high-level source-based text elaboration processes throughout their writing. The main differences concerned the density of source consultation during prewriting, on the one hand, and during pauses, on the other hand. Relationships between these characteristics of online management and text quality were minimal in fifth graders, while in undergraduate students they were more substantial as in the case of syntactic complexity. These findings suggest that with age, the online management of writing becomes more closely related to text quality. In line with a capacity view of writing, it is also concluded that the online management of writing processes of fifth graders is highly constrained by a lack of fluent text production skills which ultimately affects their text quality