Representaciones de estándares de belleza en profesionales de la salud que atienden mujeres Chilenas Diagnosticadas con trastorno de la conducta alimentaria

Los Estándares de Belleza (EB) cumplen un rol importante como fenómeno sociocultural cuya  difusión en el mundo contemporáneo influyen en la manifestación de Trastornos de la Conducta Alimentaria (TCA), mayoritariamente en mujeres. Es así como a pesar de su formación, las Profesionales de la Salud (PS) que intervienen en TCA no están exentas de la influencia de los EB. Es por ello que el objetivo de este estudio es describir las representaciones de los EB de las PS que atienden población chilena adulta joven diagnosticada con TCA. Se empleó una metodología cualitativa, a través de entrevistas en profundidad a  nueve PS. Los resultados principales muestran que las profesionales coinciden en que el sistema ha influido históricamente en la construcción de EB, dotando de mandatos y prototipos, llevando a las mujeres a caer en dietas perjudiciales para la salud con la finalidad de alcanzar el cuerpo esperado socialmente y sentir pertenencia. Siendo en la actualidad las redes sociales, familia, amigos, ámbito educativo y laboral mantenedores de estos EB. Es así como las profesionales han empleado distintas estrategias para que estos EB no interfieran en su ejercicio profesiona

Periocular Myxoma in a Child

Myxomas are locally invasive, benign mesenchymal neoplasms with odontogenic, osteogenic, or soft tissue origin. Facial myxomas probably account for less than 0.5% of all paranasal sinus and nasal tumors. We report a case of a left painless periocular mass in a 11-month-old girl. The lesion was resected with a clinical diagnosis of lacrimal sac tumor. Histopathology and immunohistochemistry proved the tumor to be a myxoma. There has been no recurrence after 4 years of followup. Midfacial myxomas should be differentiated from other benign and malignant tumors such as dermoid, hamartoma, neurofibroma, nasolacrimal duct cyst, and sarcomas in particular embryonal rhabdomyosarcoma. Because of the infiltrative nature of these tumors, a wide surgery is required to achieve clear resection margins and avoid recurrence

Ambition meets reality:Achieving GHG emission reduction targets in the livestock sector of Latin America

Livestock production is a very relevant source of income and agricultural greenhouse gas (GHG) emissions in Colombia, Brazil, Argentina, Costa Rica, Uruguay, Mexico, and Peru. Several management and technological options with enteric methane mitigation potential have been evaluated and their scaling is anticipated to contribute toward achieving GHG emission reduction targets in the framework of the Paris Agreement. Yet, widespread adoption of promising mitigation options remains limited, raising questions as to whether envisaged emission reduction targets are achievable. Using findings from local studies, we explore the mitigation potentials of technologies and management practices currently proposed to mitigate enteric methane emissions from cattle production systems in the higher emitting countries of Latin America. We then discuss barriers for adopting innovations that significantly reduce cattle-based enteric methane emissions and the major shifts in policy and practice that are needed to raise national ambitions in the high emitting countries. Using the latest science and current thinking, we provide our perspective on an inclusive approach and re-imagine how the academic, research, business and public policy sectors can support and incentivize the changes needed to raise the level of ambition and achieve sustainable development goals (SDG), considering actions from the farm to the national scale

Effectiveness of Modified Vaccinia Ankara-Bavaria Nordic Vaccination in a Population at High Risk of Mpox: A Spanish Cohort Study

Background: With over 7,500 cases notified since April 2022, Spain has experienced the highest incidence of mpox in Europe. From July 12th onwards, the Modified Vaccinia Ankara-Bavaria Nordic (MVA-BN) smallpox vaccine was offered as pre-exposure prophylaxis for individuals at high-risk of mpox, including those receiving pre-exposure prophylaxis for HIV (HIV-PrEP). Our aim was to assess the effectiveness of one dose of MVA-BN vaccine as pre-exposure against mpox virus (MPXV) infection in persons on HIV-PrEP. Methods: We conducted a national retrospective cohort study between July 12 and December 12, 2022. Individuals ≥18 years, receiving HIV-PrEP as of July 12 and with no previous MPXV infection or vaccination were eligible. Each day, we matched individuals receiving a first dose of MVA-BN vaccine and unvaccinated controls of the same age group and region. We used a Kaplan-Meier estimator and calculate risk ratios (RR) and vaccine effectiveness (VE = 1-RR). Results: We included 5,660 matched pairs, with a median follow-up of 62 days (interquartile range 24-97). Mpox cumulative incidence was 5.6 per 1,000 (25 cases) in unvaccinated and 3.5 per 1,000 (18 cases) in vaccinated. No effect was found during days 0-6 post-vaccination (VE -38.3; 95% confidence interval (95%CI): -332.7; 46.4), but VE was 65% in ≥7 days (95%CI 22.9; 88.0) and 79% in ≥14 days (95%CI 33.3; 100.0) post-vaccination. Conclusions: One dose of MVA-BN vaccine offered protection against mpox in a most-at-risk population shortly after the vaccination. Further studies need to assess the VE of a second dose and the duration of protection over time.S

Gestión cultural: retos y experiencias desde la academia

Gestión Cultural: retos y experiencias desde la academia es la compilación de dieciocho trabajos de titulación de estudiantes de la segunda y tercera cohorte de la Maestría en Gestión Cultural que oferta la Universidad Politécnica Salesiana en sus sedes de Cuenca, Quito y Guayaquil. Este programa de posgrado surgió como respuesta a la necesidad de cualificar a profesionales ya vinculados al sector y que provienen de otras disciplinas académicas; así como de nuevos actores y gestores que dinamicen la gestión cultural del país. Los trabajos aquí presentados (artículos y proyectos de titulación) son una muestra de la formación multidisciplinaria de profesionales a nivel nacional, preparados para desarrollar modelos de gestión cultural. Representan una muestra de la formación especializada en la gestión de los recursos e industrias culturales; dominio de los conceptos de cultura, patrimonio e identidad; habilidades en la ejecución de proyectos culturales; aplicación de tecnologías especializadas a los distintos campos del sector cultural; conocimiento de marco legislativo y políticas cultuales; manejo de la comunicación y mediación cultural

Strategies to achieve the GHG Mitigation Goals of the livestock sector in Latin America

Livestock production is a fundamental source of income and greenhouse gas (GHG) emissions in Latin American countries. 20 percent of the region's emissions come from agriculture, 70 percent of which comes from livestock. There are several management and technology options with enteric methane mitigation potential that have been evaluated and their scale is expected to contribute to achieving the GHG emission reduction targets under the Paris Agreement. These technologies include management of the animal diet, reproductive control, administration of supplements, and reduction of the age at slaughter, among others. However, widespread adoption of promising mitigation options remains limited, raising questions about whether the planned emission reduction targets are achievable. Using the results of local studies, we have explored the mitigation potentials of currently proposed management technologies and practices to mitigate enteric methane emissions from livestock production systems in Latin American countries with the highest emissions. We then discuss the barriers to adopting innovations that significantly reduce enteric methane emissions from livestock and the main changes in policies and practices necessary to raise national ambitions in high-emission countries. Drawing on today's latest science and thought, we take our perspective to an inclusive approach and reimagine how the academic, research, business and public policy sectors can support and incentivize the changes necessary to raise the level of ambition and achieve goals of sustainable development, taking into account actions from the farm to the national scale. Some improvements identified and that need to be made are improving access to information through effective technology transfer plans, access to financial products by small producers, and establishing seed multiplication systems for fodder materials

Relationship between IGF-1 and body weight in inflammatory bowel diseases: Cellular and molecular mechanisms involved

Inflammatory bowel diseases (IBD), represented by ulcerative colitis (UC) and Crohn''s disease (CD), are characterized by chronic inflammation of the gastrointestinal tract, what leads to diarrhea, malnutrition, and weight loss. Depression of the growth hormone-insulin-like growth factor-1 axis (GH-IGF-1 axis) could be responsible of these symptoms. We demonstrate that long-term treatment (54 weeks) of adult CD patients with adalimumab (ADA) results in a decrease in serum IGF-1 without changes in serum IGF-1 binding protein (IGF1BP4). These results prompted us to conduct a preclinical study to test the efficiency of IGF-1 in the medication for experimental colitis. IGF-1 treatment of rats with DSS-induced colitis has a beneficial effect on the following circulating biochemical parameters: glucose, albumin, and total protein levels. In this experimental group we also observed healthy maintenance of colon size, body weight, and lean mass in comparison with the DSS-only group. Histological analysis revealed restoration of the mucosal barrier with the IGF-1 treatment, which was characterized by healthy quantities of mucin production, structural maintenance of adherers junctions (AJs), recuperation of E-cadherin and ß-catenin levels and decrease in infiltrating immune cells and in metalloproteinase-2 levels. The experimentally induced colitis caused activation of apoptosis markers, including cleaved caspase 3, caspase 8, and PARP and decreases cell-cycle checkpoint activators including phosphorylated Rb, cyclin E, and E2F1. The IGF-1 treatment inhibited cyclin E depletion and partially protects PARP levels. The beneficial effects of IGF-1 in experimental colitis could be explained by a re-sensitization of the IGF-1/IRS-1/AKT cascade to exogenous IGF-1. Given these results, we postulate that IGF-1 treatment of IBD patients could prove to be successful in reducing disease pathology. © 2021 The Author

Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

The authors wish to make the following corrections to this paper [...]

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery

Universidad, género, docencia e igualdad

La Red de investigación en docencia universitaria “Universidad, docencia, genero e igualdad” persigue avanzar en la calidad e innovación de las enseñanzas universitarias a partir de la inclusión de la perspectiva de género. Se busca dar cumplimiento a las directrices generales de los nuevos planes de estudio respecto del principio de igualdad de oportunidades entre hombres y mujeres en la formación universitaria (Real Decreto 1393/2007. BOE nº 260, 30 de octubre de 2007). En la cuarta edición de la Red, y dada su composición multidisciplinar, se desarrollaron tres líneas de investigación: 1) mantenimiento del “Portal web con recursos docentes con perspectiva de género”, proyecto financiado por el Instituto de la Mujer (PACUI, 2012) e iniciado en el curso 2012-2013; 2) desarrollo (primera versión) de “iLengUA”, una herramienta informática para un discurso inclusivo e igualitario; y 3) diseño de la Guía para una orientación universitaria inclusiva