633 research outputs found
Femto-Photography: Capturing Light in Motion
We show a technique to capture ultrafast movies of light in motion and synthesize physically valid visualizations. The effective exposure time for each frame is under two picoseconds (ps). Capturing a 2D video with this time resolution is highly challenging, given the extermely low SNR associated with a picosecond exposure time, as well as the absence of 2D cameras that can provide such a shutter speed. We re-purpose modern imaging hardware to record an ensemble average of repeatable events that are synchronized to a streak tube, and we introduce reconstruction methods to visualize propagation of light pulses through macroscopic scenes. Capturing two-dimensional movies with picosecond resolution, we observe many interesting and complex light transport effects, including multibounce scattering, delayed mirror reflections, and subsurface scattering. We notice that the time instances recorded by the camera, i.e. “camera time” is different from the the time of the events as they happen locally at the scene location, i.e. world time. We introduce a notion of time warp between the two space time coordinate systems, and rewarp the space-time movie for a different perspective
Celestial mechanics in Newtonian-like gravity with variable
A Newtonian-like theory inspired by the Brans-Dicke gravitational Lagrangian
has been recently proposed in Ref. arXiv:2009.04434(v4). This work demonstrates
that the modified gravitational force acting on a test particle is analogous to
that derived from the Manev potential. Specifically, an additional term
emerges alongside the conventional Newtonian component. We
analyse the predicted expression for the pericenter advance and the Roche limit
and use them to constraint the theory's single free parameter which is
analogous to the Brans-Dicke parameter. At the same time this theory is able to
solve the advance of Mercury's perihelion, we also show that there is no
relevant impact on the Roche limit in comparison to the well known Newtonian
results.Comment: 11 pages, 4 figures, version matching the one published in EPJ
Losartan Treatment Attenuates Tumor-induced Myocardial Dysfunction
Fatigue and muscle wasting are common symptoms experienced by cancer patients. Data from animal models demonstrate that angiotensin is involved in tumor-induced muscle wasting, and that tumor growth can independently affect myocardial function, which could contribute to fatigue in cancer patients. In clinical studies, inhibitors of angiotensin converting enzyme (ACE) can prevent the development of chemotherapy-induced cardiovascular dysfunction, suggesting a mechanistic role for the renin–angiotensin–aldosterone system (RAAS). In the present study, we investigated whether an angiotensin (AT) 1-receptor antagonist could prevent the development of tumor-associated myocardial dysfunction. Methods and results: Colon26 adenocarcinoma (c26) cells were implanted into female CD2F1 mice at 8 weeks of age. Simultaneously, mice were administered Losartan (10 mg/kg) daily via their drinking water. In vivo echocardiography, blood pressure, in vitro cardiomyocyte function, cell proliferation assays, and measures of systemic inflammation and myocardial protein degradation were performed 19 days following tumor cell injection. Losartan treatment prevented tumor-induced loss of muscle mass and in vitro c26 cell proliferation, decreased tumor weight, and attenuated myocardial expression of interleukin-6. Furthermore, Losartan treatment mitigated tumor-associated alterations in calcium signaling in cardiomyocytes, which was associated with improved myocyte contraction velocity, systolic function, and blood pressures in the hearts of tumor-bearing mice. Conclusions: These data suggest that Losartan may mitigate tumor-induced myocardial dysfunction and inflammation
Optimization of an Externally Mixed Biogas Plant Using a Robust CFD Method
Biogas plants have to be continuously or periodically mixed to ensure the homogenization of fermenting and fresh
substrate. Externally installed mixers provide easier access than submerged mixers but concerns of insufficient
mixing deter many operators from using this technology. In this paper, a new approach to improve homogenization
of the substrate mixture is proposed by optimizing external mixer configurations across a wide range of rheological
properties. Robust optimization of a biogas reactor is coupled with CFD simulations to improve parameters for the
angles of inflow and the position of the substrate outlet in a large-scale fermenter. The optimization objective is to
minimize the area in the tank which is poorly mixed. We propose to define this “dead volume zone” as the region
in which the velocity magnitude during mixing falls below a certain threshold. Different dry substance contents are
being investigated to account for the varying rheological properties of different substrate compositions. The velocity
thresholds are calculated for each dry substance content from the mixer-tank configuration of a real biogas reactor
in Brandenburg, Germany (BGA Warsow GmbH & Co.KG). The robust optimization results comprising the whole
range of rheological properties are compared to simulations of the original configuration and to optimization results
for each individual dry substance content. The robust CFD-based optimized configurations reduce the dead volume
zones significantly across all dry substance contents compared to the original configuration. The outcomes of this
paper can be particularly useful for plant manufacturers and operators for optimal mixer placement in industrial
size biogas fermenters.BMBF - ROENOBIO project with contract number
05M2013UTA (Germany),
DFG - RTG 2126 Algorithmic Optimization (Germany
A new beamline for laser spin-polarization at ISOLDE
A beamline dedicated to the production of laser-polarized radioactive beams
has been constructed at ISOLDE, CERN. We present here different simulations
leading to the design and construction of the setup, as well as technical
details of the full setup and examples of the achieved polarizations for
several radioisotopes. Beamline simulations show a good transmission through
the entire line, in agreement with observations. Simulations of the induced
nuclear spin-polarization as a function of atom-laser interaction length are
presented for Na, [1] and for Ar, which is studied in this
work. Adiabatic spin rotation of the spin-polarized ensemble of atoms, and how
this influences the observed nuclear ensemble polarization, are also performed
for the same nuclei. For Ar, we show that multiple-frequency pumping
enhances the ensemble polarization by a factor 1.85, in agreement with
predictions from a rate equations model.
[1] J. Phys. G: Nucl. Part. Phys./174408400
TOSCA-based orchestration of complex clusters at the IaaS level
[EN] This paper describes the adoption and extension of the TOSCA standard by the INDIGO-DataCloud project for the definition and deployment of complex computing clusters together with the required support in both OpenStack and OpenNebula, carried out in close collaboration with industry partners such as IBM. Two examples of these clusters are described in this paper, the definition of an elastic computing cluster to support the Galaxy bioinformatics application where the nodes are dynamically added and removed from the cluster to adapt to the workload, and the definition of an scalable Apache Mesos cluster for the execution of batch jobs and support for long-running services. The coupling of TOSCA with Ansible Roles to perform automated installation has resulted in the definition of high-level, deterministic templates to provision complex computing clusters across different Cloud sites.The authors would like to thank the European Commission for the financial support for project
INDIGO-DataCloud (RIA 653549)Caballer Fernández, M.; Donvito, G.; Moltó, G.; Rocha, R.; Velten, M. (2017). TOSCA-based orchestration of complex clusters at the IaaS level. Journal of Physics: Conference Series (Online). 898:1-8. https://doi.org/10.1088/1742-6596/898/8/082036S1889
Effects of serum proteins on corrosion behavior of ISO 5832–9 alloy modified by titania coatings
Stainless steel ISO 5832–9 type is often used to
perform implants which operate in protein-containing physiological
environments. The interaction between proteins and
surface of the implant may affect its corrosive properties. The
aim of this work was to study the effect of selected serum
proteins (albumin and γ-globulins) on the corrosion of ISO
5832–9 alloy (trade name M30NW) which surface was modified
by titania coatings. These coatings were obtained by sol–
gel method and heated at temperatures of 400 and 800 °C. To
evaluate the effect of the proteins, the corrosion tests were
performed with and without the addition of proteins with
concentration of 1 g L−1 to the physiological saline solution
(0.9 % NaCl, pH 7.4) at 37 °C. The tests were carried out
within 7 days. The following electrochemical methods were
used: open circuit potential, linear polarization resistance, and
electrochemical impedance spectroscopy. In addition, surface
analysis by optical microscopy and X-ray photoelectron spectroscopy
(XPS) method was done at the end of weekly corrosion
tests. The results of corrosion tests showed that M30NW
alloy both uncoated and modified with titania coatings exhibits
a very good corrosion resistance during weekly exposition
to corrosion medium. The best corrosion resistance in
0.9 % NaCl solution is shown by alloy samples modified by
titania coating annealed at 400 °C. The serumproteins have no
significant effect onto corrosion of investigated biomedical
steel. The XPS results confirmed the presence of proteins on
the alloy surface after 7 days of immersion in proteincontaining
solutions.The investigations were supported by the National Science Centre project No. N N507 501339. The authors gratefully acknowledge Dr. Janusz
Sobczak and Dr. hab. Wojciech Lisowski from Institute of Physical
Chemistry of PAS for XPS surface analyses
Femto-photography: capturing and visualizing the propagation of light
We present femto-photography, a novel imaging technique to capture and visualize the propagation of light. With an effective exposure time of 1.85 picoseconds (ps) per frame, we reconstruct movies of ultrafast events at an equivalent resolution of about one half trillion frames per second. Because cameras with this shutter speed do not exist, we re-purpose modern imaging hardware to record an ensemble average of repeatable events that are synchronized to a streak sensor, in which the time of arrival of light from the scene is coded in one of the sensor's spatial dimensions. We introduce reconstruction methods that allow us to visualize the propagation of femtosecond light pulses through macroscopic scenes; at such fast resolution, we must consider the notion of time-unwarping between the camera's and the world's space-time coordinate systems to take into account effects associated with the finite speed of light. We apply our femto-photography technique to visualizations of very different scenes, which allow us to observe the rich dynamics of time-resolved light transport effects, including scattering, specular reflections, diffuse interreflections, diffraction, caustics, and subsurface scattering. Our work has potential applications in artistic, educational, and scientific visualizations; industrial imaging to analyze material properties; and medical imaging to reconstruct subsurface elements. In addition, our time-resolved technique may motivate new forms of computational photography.MIT Media Lab ConsortiumLincoln LaboratoryMassachusetts Institute of Technology. Institute for Soldier NanotechnologiesAlfred P. Sloan Foundation (Research Fellowship)United States. Defense Advanced Research Projects Agency (Young Faculty Award
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