An integrated physical and cost-benefit approach to assess groins as a coastal erosion mitigation strategy

Future investments required for the construction and maintenance of coastal defense interventions are expected to increase, due to increasing coastal erosion issues along social, environmental and economically valuable coastal areas. The high costs related with coastal defense interventions require improved knowledge on their performance, considering impacts, costs and benefits. Despite the existence of several cost-benefit approaches applied to coastal zones, in this study a well-defined, sequential and integrated methodology supported by already existent numerical models is developed and applied to assess the effectiveness (shoreline evolution impacts), costs and benefits of different coastal defense interventions. This methodology encompasses three integrated modules, including a shoreline evolution module (to estimate areas of territory maintained, gained or lost over time), a coastal structure pre-design module (to estimate material volumes of coastal works) and a cost-benefit evaluation module (to assess cost-benefit evaluation criteria). The approach allows for the physical and economic comparison of different coastal defense intervention scenarios, helping coastal management and planning entities to define strategies. In this study, the proposed methodology was applied to evaluate the performance of different groin scenarios, based on a hypothetical case study. The case study allowed highlighting the importance of the physical and economic analysis of different scenarios. Results show that the definition of coastal defense interventions is complex where, on the one hand, best physical solutions are sometimes related to very high costs and, on the other hand, best economic scenarios lead to high territory losses. Thus, the innovative approach presented in this study shows that an integrated analysis of shoreline evolution, coastal intervention design and subsequent costs and benefits allows to improve the physical and economic performances of coastal defense interventions.publishe

Fatores de Risco para o Desenvolvimento de Síndrome Pós-Quimioembolização após Quimioembolização Hepática para Tratamento de Hepatocarcinoma

Introduction: Hepatic transarterial chemoembolization is a widely used technique for the treatment of hepatocellular carcinoma. The most common complication of this procedure is postembolization syndrome. The main objective of this study was to assess risk factors for the development of postembolization syndrome. Material and Methods: Single-centre retrospective analysis of 563 hepatic transarterial chemoembolization procedures from January 1st, 2014 – December 31st, 2015. Hepatic transarterial chemoembolization was performed with ½ - 2 vials of 100 - 300 μm microspheres loaded with doxorubicin. Patients who experienced postembolization syndrome were identified based on prolongation of hospitalization due to pain, fever, nausea and/or vomiting. A control group with the patients who did not have postembolization syndrome was randomly created (three controls for one case). Descriptive analysis and multivariate logistic regression were performed. Results: The overall prevalence of postembolization syndrome was 6.2%. Hepatic transarterial chemoembolization with doxorubicin dosage above 75 mg (more than one vial), the size of the largest nodule and female gender had statistically significant relation with development of postembolization syndrome (p = 0.030, p = 0.046 and p = 0.037, respectively). Discussion: Doxorrubicin dosage above 75 mg is associated with a higher risk of postembolization syndrome. This result can be helpful for decision-making in clinical practice, whenever it is possible to avoid a higher dose without compromising the efficacy of the treatment. The size of the largest nodule and female gender also constitute risk factors for postembolization syndrome. The other variables studied were not related to the development of postembolization syndrome. Conclusion: The dose of doxorrubicin, the size of the largest nodule treated and female gender are potential risk factors for the development of postembolization syndrome after hepatic transarterial chemoembolization for hepatocellular carcinoma.info:eu-repo/semantics/publishedVersio

Real-time tracking system for a moored oil tanker: a kalman filter approach

This paper presents a tracking system developed to study the behavior of an oil tanker moored at the Berth "A" of the Leixões oli terminal, Porto, Portugal

Tuning peptide-based hydrogels: co-assembly with composites driving the highway to technological applications

Self-assembled peptide-based gels provide several advantages for technological applications. Recently, the co-assembly of gelators has been a strategy to modulate and tune gel properties and even implement stimuli-responsiveness. However, it still comprises limitations regarding the required library of compounds and outcoming properties. Hence, efforts have been made to combine peptide-based gels and (in)organic composites (e.g., magnetic nanoparticles, metal nanoparticles, liposomes, graphene, silica, clay, titanium dioxide, cadmium sulfide) to endow stimuli-responsive materials and achieve suitable properties in several fields ranging from optoelectronics to biomedical. Herein, we discuss the recent developments with composite peptide-based gels including the fabrication, tunability of gels' properties, and challenges on (bio)technological applications.This work was funded by the Portuguese Foundation for Science and Technology (FCT) in the framework of the Strategic Funding of CF-UM-UP (UIDB/04650/2020) and CQUM (UIDB/00686/2020), and by Ministerio de Economía y Competitividad de España (PID2020-113704RB-I00 and PID2020-119242RB-I00), Xunta de Galicia (Centro Singular de Investigación de Galicia—Accreditation 2019-2022 ED431G 2019/06 and IN607A 2018/5 and project ED431C 2020-06), and European Union (EU-ERDF Interreg V-A—Spain-Portugal 0245_IBEROS_1_E, 0712_ACUINANO_1_E, and 0624_2IQBIONEURO_6_E, and Interreg Atlantic Area NANOCULTURE 1.102.531), and the European Union H2020-MSCA-RISE-2019 PEPSA-MATE 872233 project. S.R.S. Veloso acknowledges FCT for a PhD grant (SFRH/BD/144017/2019). Support from MAP-Fis Doctoral Programme is also acknowledged

Análise Paramétrica do Transporte Sedimentar a Barlamar de um Esporão: Impacto na Evolução da Linha de Costa.

Este trabalho pretende contribuir para a otimização do desempenho do programa de modelação numérica LTC (Long Term Configuration), através da análise do comportamento da linha de costa, em função da alteração gradual de determinados parâmetros de entrada. Para tal foi avaliada a influência dos parâmetros e a sensibilidade do modelo num caso de estudo com uma extensão de 10km de praia, a barlamar de um esporão de 145m de comprimento. Numa primeira análise foi avaliada a influência da definição da largura ativa dos perfis transversais na proximidade a sotamar do esporão. Para efetuar esta avaliação, foi definido um valor de profundidade de fecho igual ao do perfil imediatamente a barlamar, ao longo de diferentes extensões a sotamar, em função do comprimento do esporão. Numa segunda e terceira análises foi estudado o efeito da alteração dos ângulos de atrito dos sedimentos e da batimetria inicial, respetivamente. A alteração do ângulo de atrito na direção transversal não originou alteração da posição da linha de costa, enquanto que o aumento do ângulo de atrito na direção longitudinal originou um avanço da posição da linha de costa. O cenário onde se procedeu à alteração da batimetria inicial foi o que registou maior impacto na posição da linha de costa, com diferenças significativas nos resultados. Uma última análise consistiu no estudo da influência do coeficiente de transporte sedimentar. A configuração da linha de costa foi calculada para diferentes instantes de cálculo, correspondendo aos tempos de enchimento obtidos para cada valor do coeficiente de transporte e a um tempo de cerca de 40 anos, correspondente a uma situação de equilíbrio da praia. Verifica-se que o valor do coeficiente de transporte apenas afeta a rapidez com que a linha de costa atinge determinada posição. Palavras-chave: Análise de sensibilidade; Coeficiente de transporte; LTC; Modelo numérico; Posição da linha de costa

Lesiones faciales en niños y adolescentes víctimas de agresiones

Child maltreatment may occur as the intentional use of power, effective or attempted, against children under 18 years old, that results or may result in actual or potential harm. It affects a vulnerable population, causing physical and/or emotional consequences persisting throughout their lives. This study aimed to characterize episodes of child maltreatment, with focus on facial injuries, in a Brazilian city (Teresina, PI). This is a retrospective study with a quantitative approach, carried out in the database at the Institute of Forensic MedicineinTeresina, between the years 2017 and 2019. All reports of bodily injury of children from 0 to 18 years were collected and statistically analyzed (SPSS 22.0). During the period analysis, 811 reports of bodily injury were identified. There was a predominance of female victims aged between 12 and 18 years old, the involvement of men with some family relationship with the victim was highly associated. Facial injuries represented 35.8% of the whole sample and 98.6% of those found in the head and neck region (41,6% of the total). The orbital (29.0%) was the most affected site, followed by the frontal (25.9%), malar (23.4%), labial (17.6%) and cheek area (11.4%). There is a high prevalence of injuries to the head and neck region, this factemphasizes the importance of a trained professional, especially a dental surgeon, in the analysis and interpretation of these injuries during forensic examination.info:eu-repo/semantics/publishedVersio

Design of a new test chamber for evaluation of the toxicity of rubber infill

A test chamber was projected and built (according to ISO 16000-9 Standard) to simulate atmospheric conditions experienced by rubber infill (when applied in synthetic turf pitches) and measure accurately the airborne emissions of pollutants such as dusts and volatile organic compounds (VOC), as well as pollutants present in leachates. It should be pointed out that standard ISO 16000-9 is only concerned with the determination of the emission of VOC from building products and furnishing (not specific of synthetic turf materials), whereas other standards are concerned with the emission of leachates only. This procedure is to be considered as a technical option to the lysimeter "global turf system evaluation" when the rubber infill alone is to be evaluated. The advantage of the proposed option considering this "test chamber" is its simplicity and economy. This test chamber is actually installed and being used for tests in LAIST