71 research outputs found
Crafting Conscious Employee Engagement through Wellbeing: A Key Differentiator to Long-Term Organizational Success within the Hospitality Industry
Discussions on pandemics that hit the human race have dominated the scientific research world, on the contrary, due to the developments in technology and globalisation the work environment has evolved into a complex space and for this reason, there is a wide research gap on how the workforce can get back to normal or cope with an ever-changing pandemic phenomenon. The objectives of the current paper are aligned to identify the impact of Covid-19 on different levels of the employeesā life, to analyse the effect on mental health and wellbeing, and to formulate a relationship between mindful employee engagement and its impact on organisational success. The current scenario requires the employees to continue working from home for the businesses to sustain themselves in the future. By reviewing 20 research articles, an understanding is developed of the remote-work model and its positive and negative impacts on employees as well as organisations. Using a semi-structured questionnaire to interview service industry professionals, data has been gathered. Using a semi-structured analysis the authors aim to illustrate the pandemicās effects from the employeesā perspective. The researchers found three significant findings: loyalty to self-preservation, mindfulness to address mental health and improve performance and success of organisations during the pandemic depends on a purpose-driven culture
COMPARISON OF ORAL CLONIDINE WITH ORAL MIDAZOLAM IN MANAGING AGITATION FOLLOWING SEVOFLURANE ANESTHESIA Ć¢ā¬ā A PROSPECTIVE, RANDOMIZED, DOUBLE BLINDED STUDY
ABSTRACT:Objective: Emergence agitation is a major problem during recovery from anesthetic agents like sevoflurane, particularly in children. This study had compared the effects of oral clonidine with oral midazolam in reducing the incidence of emergence agitation following sevoflurane anesthesia.Methods: 50 children of ASA status I and II aged between 3-8 years were randomly allotted to one of the two groups, each group comprising 25 children. Group I children were given oral Midazolam 0.5 mg/kg and Group II children were given oral Clonidine 4 mcg/kg 30 min before the induction of anesthesia. Emergence reaction was analyzed using modified objective pain scale in all children following sevoflurane administration.Results: The total agitation score was significantly less in clonidine group in comparison to midazolam group during the first hour of post operative period (P<0.05).No remarkable change in the hemodynamics or oxygen saturation was observed in both groups.Conclusion: Premedication of oral clonidine 4 microgram per kg is superior to oral midazolam 0.5 mg per kg in reducing the incidence of emergence agitation following sevoflurane anesthesia.Keywords: sevoflurane, recovery, emergence agitation, clonidine, midazolam
Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures
Human telomeric DNA G-quadruplex has been considered as an attractive target for cancer therapeutic intervention. The telomeric sequence shows intrinsic structure polymorphism. Here we report a novel intramolecular G-quadruplex structure formed by a variant human telomeric sequence in K+ solution. This sequence forms a basket-type intramolecular G-quadruplex with only two G-tetrads but multiple-layer capping structures formed by loop residues. While it is shown that this structure can only be detected in the specifically truncated telomeric sequences without any 5ā²-flanking residues, our results suggest that this two-G-tetrad conformation is likely to be an intermediate form of the interconversion of different telomeric G-quadruplex conformations
Tissue reactions to Cysticercus cellulosae in man
1.1. The histological changes in three cases of human cysticercosis, all involving the brain with one involving in addition the heart muscle, the diaphragm, the intercostal and pectoral muscles, are described. 2.2. It is demonstrated that the nature of the tissue reaction is similar in the brain and the other organs and consists in the formation of a capsule of mesenchymal tissue with an inner necrotic zone, a middle fibrous and plasmacytic zone and an outer zone of granulation tissue. With the gradual absorption of the dead parasite the reaction becomes more marked and ultimately a fibrous scar is formed especially in the brain. Calcification of cerebral cysts is not very common. 3.3. In the brain, this mesenchymal capsule is surrounded by an area of gliosis where the nerve cells have undergone degeneration. 4.4. The formation of multiple scars in the brain and the overlying meninges is put forward as the main pathological basis of the nervous symptoms
Study - Utility of polymerase chain reaction as a diagnostic tool in cutaneous tuberculosis
Background: Differentiation of cutaneous tuberculosis from other
infective granulomas of the skin is difficult due to paucity of the
organisms in tissue biopsies. Polymerase chain reaction (PCR) is a
newer technique to identify the DNA of Mycobacterium tuberculosis in
the tissues. Aim: We examined the utility of PCR as a tool for rapid
diagnosis of cutaneous tuberculosis especially in cases negative by ZN
staining and culture. Material and Methods: Twenty five random skin
biopsies from patients with various types of cutaneous tuberculosis
were subjected to PCR. Results: An overall positivity of 64% was
observed, which is comparable to other series. Seventy five percent of
lupus vulgaris cases, 62.2% of tuberculosis verrucosa cutis and 50% of
scrofuloderma cases showed PCR positivity. Conclusion: Though useful,
the cost and the technique involved limit the use of PCR in developing
countries like ours
Perioperative management of a patient with Gilberts syndrome and rheumatic heart disease
Anaesthetic management of patients with hepatic dysfunction can be quite challenging, as many anaesthetic agents are metabolized by liver. Heart disease on anti coagulation can pose additional challenge. Here we report a case of Gilbertā²s syndrome with rheumatic heart disease on anti coagulation posted for elective hernia repair
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