168 research outputs found

    Mediación familiar en casos de ruptura conyugal. La inclusión de los menores en el procedimiento

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    Esta revisión bibliográfica pretende analizar la ruptura conyugal partiendo de un análisis exhaustivo de las posibles vías útiles en este proceso. El abordaje del trabajo parte de la definición de familia desde una perspectiva psicosocial hasta adentrarse en una dimensión jurídica, en la que se podrá apreciar cómo ha evolucionado el procedimiento de separación o ruptura en la pareja. La parte principal del estudio se centra en examinar cuáles son los mecanismos de resolución de conflictos, así como la elección de aquellos que impliquen un menor impacto negativo para los miembros de la unidad familiar. De entre éstos últimos destacaremos la mediación familiar. La mediación familiar resulta un mecanismo óptimo para abordar la disolución matrimonial y familiar sin provocar la ruptura del vínculo de responsabilidad parental. En la congruencia de este proceso se contempla la posibilidad que los hijos (agentes activos del conflicto), puedan ser escuchados y participen de forma activa en el transcurso de la mediación, en el supuesto que fuese necesario para consolidar el acuerdo. Se propone un "modelo de entrevista". Este prototipo sería válido en las sesiones de mediación en las que los menores tengan que reproducir la manera en la que ellos entienden el conflicto, así como aportar su opinión al programar el régimen regulador de visitas.Departamento de Derecho CivilMáster en Mediación y Resolución Extrajudicial de Conflicto

    La presencia femenina en la política española. Los casos del PP y el PSOE (1986/2016)

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    Fac. de Ciencias Políticas y SociologíaFALSEsubmitte

    In utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts

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    The research leading to these results has received funding from Instituto de Salud Carlos III and European Union's FEDER funds (CP16/ 00128 - the ENDOLUNG project, and PI17/01194 - the INMA-AdoRespi Project), the European Community's Seventh Framework Programme (FP7/2007-206) under grant agreement no 308,333 - the HELIX project -, and from the EC's Horizon 2020 research and innovation programme under grant agreement No 874,583 - the ATHLETE project.Background: In utero exposure to bisphenols, widely used in consumer products, may alter lung development and increase the risk of respiratory morbidity in the offspring. However, evidence is scarce and mostly focused on bisphenol A (BPA) only. Objective: To examine the associations of in utero exposure to BPA, bisphenol F (BPF), and bisphenol S (BPS) with asthma, wheeze, and lung function in school-age children, and whether these associations differ by sex. Methods: We included 3,007 mother–child pairs from eight European birth cohorts. Bisphenol concentrations were determined in maternal urine samples collected during pregnancy (1999–2010). Between 7 and 11 years of age, current asthma and wheeze were assessed from questionnaires and lung function by spirometry. Wheezing patterns were constructed from questionnaires from early to mid-childhood. We performed adjusted randomeffects meta-analysis on individual participant data. Results: Exposure to BPA was prevalent with 90% of maternal samples containing concentrations above detection limits. BPF and BPS were found in 27% and 49% of samples. In utero exposure to BPA was associated with higher odds of current asthma (OR = 1.13, 95% CI = 1.01, 1.27) and wheeze (OR = 1.14, 95% CI = 1.01, 1.30) (pinteraction sex = 0.01) among girls, but not with wheezing patterns nor lung function neither in overall nor among boys. We observed inconsistent associations of BPF and BPS with the respiratory outcomes assessed in overall and sex-stratified analyses. Conclusion: This study suggests that in utero BPA exposure may be associated with higher odds of asthma and wheeze among school-age girls.Instituto de Salud Carlos IIIEuropean Commission European Commission CP16/ 00128 PI17/01194 308,333 European Commission European Commission Joint Research Centre 874,58

    Conflicto minero en la parroquia de Pacto: límites y posibilidades de solución

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    América Latina ha sido la región más “privilegiada“ por sus recursos naturales, por ello ha captado grandes inversiones manteniendo durante años un modelo económico extractivista deficiente. La sustentabilidad en el tiempo de este tipo de desarrollo ha incrementado la insuficiencia del rol del Estado. Los conflictos socioambientales están posicionándose de forma relevante en los procesos de desarrollo así como en las agendas globales. Los conflictos se caracterizan por la diversidad en su complejidad de actores, intereses, etc. El incremento desmedido de la violencia dentro de estos ha llevado a ser un ámbito importante dentro de todos los países en el mundo. El propósito de esta investigación es analizar un caso de conflicto en el Ecuador como es el de la Parroquia de Pacto. Ya que es importante determinar las causas de los conflictos dentro de la sociedad, y conocer como el Estado ha manejado o evitado estos problemas. Es necesario examinar los impactos que tienen las actividades extractivistas dentro de las áreas sociales y ambientales, con la finalidad de dar una solución para evitar tantos enfrentamientos

    Exploring the extraction of the bioactive content from the two-phase olive mill waste and further purification by ultrafiltration

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    [EN] The two-phase olive mill waste is enormously produced in the Mediterranean area. This major waste is significantly rich in bioactive compounds that are highly valued by industry, such as phenolic and triterpenic compounds. Here, a thorough study of the most suitable solvent, extraction time and temperature for the largevolume, solid-liquid extraction of bioactive compounds has been made, in order to achieve maximum concentrations of the target compounds. Ultrasound effect has been considered. A deep characterization of the extracts by high-performance liquid chromatography coupled with electrospray-quadrupole-time of flight-mass spectrometry (LC-ESI-qToF-MS) has contributed to evaluate the effect of the operational parameters on the extraction performance. Forty-four compounds have been found and classified in their corresponding chemical families. At the optimum experimental conditions (EtOH 50% (v/v), 40 degrees C, ultrasound-assisted), more than 6.8 mg/g of bioactive content was recovered, and it was later purified by means of ultrafiltration. The membrane UP005 retained a significant percentage of the organic matter, whereas most of the bioactive compounds were recovered in the permeate. This contributed not only to revalorize this waste, but also to reduce its organic load and phytotoxicity, thus protecting the ecosystem of the final disposal zone of the residue.Funding Grant CTM2017-88645-R, funded by MCIN/AEI/10.13039/501100011033 and by ERDF A way of making Europe. Additionally, the grant PRE2018-08524 was funded by MCIN/AEI/10.13039/501100011033 and by ESF Investing in your future. Funding for open access charge: CRUE-Universitat Politècnica de València.Sánchez-Arévalo, CM.; Iborra Clar, A.; Vincent Vela, MC.; Alvarez Blanco, S. (2022). Exploring the extraction of the bioactive content from the two-phase olive mill waste and further purification by ultrafiltration. LWT - Food Science and Technology. 165:1-12. https://doi.org/10.1016/j.lwt.2022.11374211216

    The role of the interactome in the maintenance of deleterious variability in human populations

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    Recent genomic projects have revealed the existence of an unexpectedly large amount of deleterious variability in the human genome. Several hypotheses have been proposed to explain such an apparently high mutational load. However, the mechanisms by which deleterious mutations in some genes cause a pathological effect but are apparently innocuous in other genes remain largely unknown. This study searched for deleterious variants in the 1,000 genomes populations, as well as in a newly sequenced population of 252 healthy Spanish indi-viduals. In addition, variants causative of monogenic diseases and somatic variants from 41 chronic lymphocytic leukaemia patients were analysed. The deleterious variants found were analysed in the context of the interactome to understand the role of network topology in the maintenance of the observe

    Bacillus extracellular matrix modulates Botrytis metabolism and growth

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    In nature, bacteria often form communities known as biofilms, where cells are embedded in a self-produced extracellular matrix (ECM) that provides protection against external aggressions or facilitates efficient use of resources. Interactions with other microbes can significantly alter the structure of the community and thus the type of relationship with the environment. Here, we study the role of different components of Bacillus ECM in the adhesion to Botrytis hyphae, which could facilitate the efficient release of antifungal metabolites. We also describe how the different purified components of the ECM and certain Bacillus secondary metabolites (TasA, TapA, EPS, Fengycin) modulate the chemical communication between Bacillus and Botrytis, altering the physiology and ultrastructure of Botrytis.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Bovine tuberculosis and the endangered Iberian lynx.

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    We report the first case of bovine tuberculosis in a free-living Iberian lynx (Lynx pardina), an extremely endangered feline, from Doñana National Park in Spain. The isolate (Mycobacterium bovis) correlates by molecular characterization with other isolates from wild ungulates in the park, strongly suggesting an epidemiologic link. Mycobacterium bovis infects many animal species, with wild and free-ranging domestic ungulates being the main reservoirs in nature (1)

    Deciphering the chemical dialogue between Bacillus and pathogenic fungi.

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    In nature, bacteria frequently form bacterial communities known as biofilms, where cells are embedded within an extracellular matrix (ECM) that provides protection against external aggressions or facilitates the efficient uptake and utilization of available resources. Interactions with other microbes can notably alter the community structure and, consequently, the nature of the relationship with the environment1. Previous studies of our laboratory have demonstrated the significance of biofilm formation in the antagonistic interaction between Bacillus and the phytopathogenic fungi Botrytis in the melon phyllosphere2. Our hypothesis is that the ECM plays a complementary role to the structural aspects of this antagonistic interaction. In this study, we dissect how the different components of Bacillus ECM mediate the adhesion of bacterial cells to Botrytis hyphae, which could enhance the efficient release of antifungal metabolites. We also describe how several purified components of the ECM and specific secondary metabolites of Bacillus participate in the chemical communication between Bacillus and Botrytis, thereby altering the physiology and metabolism of Botrytis. Our findings unveil that during this antagonistic interaction, Botrytis secrets different oxylipins, defence molecules capable of killing Bacillus. In response, Bacillus increases the production of several secondary metabolites, which appears to have antifungal effects. Our results underscore the urgency of further investigation of these interactions with the aim of identifying and describing adaptation processes that either lead to the exclusion or coexistence of two initially antagonistic microorganisms.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tec

    SELF-EFFICACY AND COMPLEX THINKING IN HIGHER EDUCATION STUDENTS IN PERU

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    The objective of the study was to determine the relationship and predictability between self-efficacy and complex thinking in higher education students in Peru, making comparisons by gender, in 543 students aged 18 to 25 years, from four public universities to whom the scales of Self-Efficacy (EAPESA; Palenzuela, 1983) and Complex Thinking created by CIFE (2017) were applied. The results show a moderate positive relationship and complex thinking is a predictor of self-efficacy in 17.6% of the cases observed, and there are no significant differences according to gender, and most were located at medium and high levels in both variables
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