196 research outputs found

    Hamiltonian approach to QCD in Coulomb gauge - a survey of recent results

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    I report on recent results obtained within the Hamiltonian approach to QCD in Coulomb gauge. Furthermore this approach is compared to recent lattice data, which were obtained by an alternative gauge fixing method and which show an improved agreement with the continuum results. By relating the Gribov confinement scenario to the center vortex picture of confinement it is shown that the Coulomb string tension is tied to the spatial string tension. For the quark sector a vacuum wave functional is used which explicitly contains the coupling of the quarks to the transverse gluons and which results in variational equations which are free of ultraviolet divergences. The variational approach is extended to finite temperatures by compactifying a spatial dimension. The effective potential of the Polyakov loop is evaluated from the zero-temperature variational solution. For pure Yang--Mills theory, the deconfinement phase transition is found to be second order for SU(2) and first order for SU(3), in agreement with the lattice results. The corresponding critical temperatures are found to be 275MeV275 \, \mathrm{MeV} and 280MeV280 \, \mathrm{MeV}, respectively. When quarks are included, the deconfinement transition turns into a cross-over. From the dual and chiral quark condensate one finds pseudo-critical temperatures of 198MeV198 \, \mathrm{MeV} and 170MeV170 \, \mathrm{MeV}, respectively, for the deconfinement and chiral transition.Comment: Talk given by H. Reinhardt at "5th Winter Workshop on Non-Perturbative Quantum Field Theory", 22-24 March 2017, Sophia-Antipolis, France. arXiv admin note: text overlap with arXiv:1609.09370, arXiv:1510.03286, arXiv:1607.0814

    Sage Extracts as Inhibitors of Steel Corrosion in 4% HCl

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    In this paper the research of corrosion protection of steel by processing corrosion environment using various concentrations of sage extracts (Salvia officinalis) (0.5 g/dm(3), 1 g/dm(3) and 1.5 g/dm(3)) in a 4% solution of HCl was carried out. Measurements were performed using gravimetric and electrochemical methods (Tafel extrapolation method and electrochemical impedance spectroscopy). The results have showed that sage is recommendable as a possible inhibitor in 4% solutions of HCl. The research also confirms that electrochemical impedance spectroscopy is a reliable method to use for rapid corrosion tests, since the results confirm the gravimetric measurements of corrosion indicators. Determination of corrosion rate and the degree of protection using Tafel diagrams calculated on the basis of corrosion current did not give reliable results. The results show that sage may be used as a "green inhibitor" for protection of steel in a shorter period of time. The degree of protection ranges up to 64.5% for steel 2; however, since sage is environmentally friendly, it is a suitable corrosion inhibitor for shorter periods of time

    Sage Extracts as Inhibitors of Steel Corrosion in 4% HCl

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    In this paper the research of corrosion protection of steel by processing corrosion environment using various concentrations of sage extracts (Salvia officinalis) (0.5 g/dm(3), 1 g/dm(3) and 1.5 g/dm(3)) in a 4% solution of HCl was carried out. Measurements were performed using gravimetric and electrochemical methods (Tafel extrapolation method and electrochemical impedance spectroscopy). The results have showed that sage is recommendable as a possible inhibitor in 4% solutions of HCl. The research also confirms that electrochemical impedance spectroscopy is a reliable method to use for rapid corrosion tests, since the results confirm the gravimetric measurements of corrosion indicators. Determination of corrosion rate and the degree of protection using Tafel diagrams calculated on the basis of corrosion current did not give reliable results. The results show that sage may be used as a "green inhibitor" for protection of steel in a shorter period of time. The degree of protection ranges up to 64.5% for steel 2; however, since sage is environmentally friendly, it is a suitable corrosion inhibitor for shorter periods of time

    A scoping review of research on complementary and alternative medicine (CAM) and the mass media: Looking back, moving forward

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    <p>Abstract</p> <p>Background</p> <p>The use of complementary and alternative medicine (CAM) has become more common in Western developed countries in recent years, as has media reporting on CAM and related issues. Correspondingly, media reports are a primary information source regarding decisions to use CAM. Research on CAM related media reports is becoming increasingly relevant and important; however, identifying key concepts to guide future research is problematic due to the dispersed nature of completed research in this field. A scoping review was conducted to: 1) determine the amount, focus and nature of research on CAM and the mass media; and 2) summarize and disseminate related research results.</p> <p>Methods</p> <p>The main phases were: 1) searching for relevant studies; 2) selecting studies based on pre-defined inclusion criteria; 3) extracting data; and 4) collating, summarizing and reporting the results.</p> <p>Results</p> <p>Of 4,454 studies identified through various search strategies, 16 were relevant to our objectives and included in a final sample. CAM and media research has focused primarily on print media coverage of a range of CAM therapies, although only a few studies articulated differences within the range of therapies surveyed. Research has been developed through a variety of disciplinary perspectives, with a focus on representation research. The research reviewed suggests that journalists draw on a range of sources to prepare media reports, although most commonly they cite conventional (versus CAM) sources and personal anecdotes. The tone of media reports appears generally positive, which may be related to a lack of reporting on issues related to risk and safety. Finally, a variety of discourses within media representations of CAM are apparent that each appeal to a specific audience through resonance with their specific concerns.</p> <p>Conclusion</p> <p>Research on CAM and the mass media spans multiple disciplines and strategies of inquiry; however, despite the diversity in approach, it is clear that issues related to production and reception of media content are in need of research attention. To address the varied issues in a comprehensive manner, future research needs to be collaborative, involving researchers across disciplines, journalists and CAM users.</p

    The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthoraperniciosa, the causal agent of witches' broom disease of Theobroma cacao

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    This report describes the cloning, sequence and expression analysis of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene of Moniliophthora perniciosa, the most important pathogen of cocoa in Brazil. Southern blot analysis revealed the presence of a single copy of the GAPDH gene in the M. perniciosa genome (MpGAPDH). The complete MpGAPDH coding sequence contained 1,461 bp with eight introns that were conserved in the GAPDH genes of other basidiomycete species. The cis-elements in the promoter region of the MpGAPDH gene were similar to those of other basidiomycetes. Likewise, the MpGAPDH gene encoded a putative 339 amino acid protein that shared significant sequence similarity with other GAPDH proteins in fungi, plants, and metazoans. Phylogenetic analyses clustered the MPGAPDH protein with other homobasidiomycete fungi of the family Tricholomataceae. Expression analysis of the MpGAPDH gene by real-time PCR showed that this gene was more expressed (~1.3X) in the saprotrophic stage of this hemibiotrophic plant pathogen than in the biotrophic stage when grown in cacao extracts

    Phase I Evaluation of STA-1474, a Prodrug of the Novel HSP90 Inhibitor Ganetespib, in Dogs with Spontaneous Cancer

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    The novel water soluble compound STA-1474 is metabolized to ganetespib (formerly STA-9090), a potent HSP90 inhibitor previously shown to kill canine tumor cell lines in vitro and inhibit tumor growth in the setting of murine xenografts. The purpose of the following study was to extend these observations and investigate the safety and efficacy of STA-1474 in dogs with spontaneous tumors.This was a Phase 1 trial in which dogs with spontaneous tumors received STA-1474 under one of three different dosing schemes. Pharmacokinetics, toxicities, biomarker changes, and tumor responses were assessed. Twenty-five dogs with a variety of cancers were enrolled. Toxicities were primarily gastrointestinal in nature consisting of diarrhea, vomiting, inappetence and lethargy. Upregulation of HSP70 protein expression was noted in both tumor specimens and PBMCs within 7 hours following drug administration. Measurable objective responses were observed in dogs with malignant mast cell disease (n = 3), osteosarcoma (n = 1), melanoma (n = 1) and thyroid carcinoma (n = 1), for a response rate of 24% (6/25). Stable disease (>10 weeks) was seen in 3 dogs, for a resultant overall biological activity of 36% (9/25).This study provides evidence that STA-1474 exhibits biologic activity in a relevant large animal model of cancer. Given the similarities of canine and human cancers with respect to tumor biology and HSP90 activation, it is likely that STA-1474 and ganetespib will demonstrate comparable anti-cancer activity in human patients
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