Ciclo de Mejora Docente en la asignatura de Psicología de la Atención de la Percepción del Grado en Psicología

La presente comunicación describe una experiencia de diseño y realización de un Ciclo de Mejora Docente de ocho horas de duración para la asignatura de Psicología de la Atención y de la Percepción del Grado en Psicología de la Universidad de Sevilla durante el curso 2018/2019. En concreto la actividad se va a aplicar al tema de Percepción del color, que reviste una gran complejidad dentro de la asignatura

Amygdala and emotional learning in vertebrates: A comparative perspective

Gobierno de España SI2009-12761Gobierno de España RyC2006/128

Animal models of maladaptive traits: disorders in sensorimotor gating and attentional quantifiable responses as possible endophenotypes

Traditional diagnostic scales are based on a number of symptoms to evaluate and classify mental diseases. In many cases, this process becomes subjective, since the patient must calibrate the magnitude of his/her symptoms and therefore the severity of his/her disorder. A completely different approach is based on the study of the more vulnerable traits of cognitive disorders. In this regard, animal models of mental illness could be a useful tool to characterize indicators of possible cognitive dysfunctions in humans. Specifically, several cognitive disorders such as schizophrenia involve a dysfunction in the mesocorticolimbic dopaminergic system during development. These variations in dopamine levels or dopamine receptor sensibility correlate with many behavioral disturbances. These behaviors may be included in a specific phenotype and may be analyzed under controlled conditions in the laboratory. The present study provides an introductory overview of different quantitative traits that could be used as a possible risk indicator for different mental disorders, helping to define a specific endophenotype. Specifically, we examine different experimental procedures to measure impaired response in attention linked to sensorimotor gating as a possible personality trait involved in maladaptive behaviors.Ministerio de Economía y Competitividad PSI2012- 3244

Efectos de la ablación telencefálica sobre el aprendizaje apetitivo instrumental en la carpa dorada (Carassius auratus)

Efectos de la ablación telencefálica sobre el aprendizaje apetitivo instrumental en la carpa dorada (Carassius auratus). En este experimento se emplearon carpas doradas (Carassius auratus) con ablación bilateral del telencéfalo o con operación de control en un procedimiento de entrenamiento instrumental con distribución de ensayos ampliamente espaciados (un ensayo por día). Los animales fueron entrenados a nadar en un corredor bajo condiciones de reforzamiento continuo o reforzamiento parcial al 50%. Se realizaron 32 sesiones diarias de adquisición seguidas de 32 sesiones diarias de extinción en las que la comida fue suprimida. La lesión telencefálica afectó a la adquisición durante los primeros ensayos, aunque, al final, los animales lesionados alcanzaron una ejecución asintótica similar a la de los animales controles. La extinción se vio facilitada por las lesiones, independientemente del programa de reforzamiento usado durante la adquisición. Los resultados se interpretan en relación a los estudios comparativos de aprendizaje instrumental apetitivo con ensayos espaciados realizados en otros vertebrados.Goldfish received either bilateral ablation of the telencephalon or a sham operation, followed by instrumental training under widely-spaced conditions (one trial per day). Animals were trained to swim in a runway for either continuous reinforcement or 50% partial reinforcement. Thirty-two daily acquisition sessions were followed by 32 daily extinction sessions during which food was withheld. Telencephalic lesions disrupted early acquisition performance, but lessoned animals achieved an asymptotic performance similar to that of sham controls. Extinction was facilitated by the lesions, independently of the schedule of reinforcement used during acquisition. The results are interpreted in relation to comparative research on spaced-trial appetitive instrumental learning in vertebrates.Ministerio de Educación y Cultura PB96-1334Junta de Andalucía CVI-24

Beach balls: Assessing frustration tolerance in young children using a computerized task

Frustration tolerance is a skill related to emotional regulation processes and is important insofar as it affects people's social relationships and even health. Low levels of frustration tolerance in children have been associated with a greater number of externalizing symptoms such as aggression or anger. Despite its importance, there are a limited number of tasks that attempt to evaluate this construct objectively. Therefore, the aim of our work was the design of a computerized task, programmed as a videogame in order to assess frustration tolerance in children from 6 to 10 years old. The results obtained showed that the test had a good internal consistency and could be useful as an objective measure of frustration tolerance in children. In line with the literature, our data have shown no influence of gender or laterality of participants during the task and only 7% of the frustration measure could be explained by the influence of participants' age. On the other hand, the performance of the participants during the task has allowed us to classify them into six groups according to their performance, namely Low/High Frustration, Low/High Performance and Low/High Reaction Time. This test would permit to compare participants' performance with their reference group but also with their own results, facilitating the obtention of an objective assessment of frustration tolerance in young children.Ministerio de Ciencia Innovación y Universidades PID2019-110739GB-I00/AEI/10.13039/501100011033Junta de Andalucía HUM-64

Surprise-induced enhancements in the associability of Pavlovian cues facilitate learning across behavior systems

Surprising violations of outcome expectancies have long been known to enhance the associability of Pavlovian cues; that is, the rate at which the cue enters into further associations. The adaptive value of such enhancements resides in promoting new learning in the face of uncertainty. However, it is unclear whether associability enhancements reflect increased associative plasticity within a particular behavior system, or whether they can facilitate learning between a cue and any arbitrary outcome, as suggested by attentional models of conditioning. Here, we show evidence consistent with the latter hypothesis. Violating the outcome expectancies generated by a cue in an appetitive setting (feeding behavior system) facilitated subsequent learning about the cue in an aversive setting (defense behavior system). In addition to shedding light on the nature of associability enhancements, our findings offer the neuroscientist a behavioral tool to dissociate their neural substrates from those of other, behavior system- or valence-specific changes. Moreover, our results present an opportunity to utilize associability enhancements to the advantage of counterconditioning procedures in therapeutic contexts.National Institute on Drug Abuse 5R00DA036561National Institute on Drug Abuse 1R15DA051795Ministerio de Ciencia, Innovación y Universidades (MICINN) PID2019-110739 GB-I0

Conservation of Spatial Memory Function in the Pallial Forebrain of Reptiles and Ray-Finned Fishes

The hippocampus of mammals and birds is critical for spatial memory. Neuroanatomical evidence indicates that the medial cortex (MC) of reptiles and the lateral pallium (LP) of ray-finned fishes could be homologous to the hippocampus of mammals and birds. In this work, we studied the effects of lesions to the MC of turtles and to the LP of goldfish in spatial memory. Lesioned animals were trained in place, and cue maze tasks and crucial probe and transfer tests were performed. In experiment 1, MC-lesioned turtles in the place task failed to locate the goal during trials in which new start positions were used, whereas sham animals navigated directly to the goal independently of start location. In contrast, no deficit was observed in cue learning. In experiment 2, LP lesion produced a dramatic impairment in goldfish trained in the place task, whereas medial and dorsal pallium lesions did not decrease accuracy. In addition, none of these pallial lesions produced deficits in cue learning. These results indicate that lesions to the MC of turtles and to the LP of goldfish, like hippocampal lesions in mammals and birds, selectively impair map-like memory representations of the environmental space. Thus, the forebrain structures of reptiles and teleost fish neuroanatomically equivalent to the mammalian and avian hippocampus also share a central role in spatial cognition. Present results suggest that the presence of a hippocampus-dependent spatial memory system is a primitive feature of the vertebrate forebrain that has been conserved through evolution.Dirección General de Enseñanza Superior de EspañaJunta de Andalucí

Different involvement of medial prefrontal cortex and dorso-lateral striatum in automatic and controlled processing of a future conditioned stimulus

Recent studies support the idea that stimulus processing in latent inhibition can vary during the course of preexposure. Controlled attentional mechanisms are said to be important in the early stages of preexposure, while in later stages animals adopt automatic processing of the stimulus to be used for conditioning. Given this distinction, it is possible that both types of processing are governed by different neural systems, affecting differentially the retrieval of information about the stimulus. In the present study we tested if a lesion to the dorso-lateral striatum or to the medial prefrontal cortex has a selective effect on exposure to the future conditioned stimulus (CS). With this aim, animals received different amounts of exposure to the future CS. The results showed that a lesion to the medial prefrontal cortex enhanced latent inhibition in animals receiving limited preexposure to the CS, but had no effect in animals receiving extended preexposure to the CS. The lesion of the dorso-lateral striatum produced a decrease in latent inhibition, but only in animals with an extended exposure to the future conditioned stimulus. These results suggest that the dorsal striatum and medial prefrontal cortex play essential roles in controlled and automatic processes. Automatic attentional processes appear to be impaired by a lesion to the dorso-lateral striatum and facilitated by a lesion to the prefrontal cortex.Ministerio de Economía, Industria y Competitividad PSI2015-65500-

Autoimmune Diseases and COVID-19 as Risk Factors for Poor Outcomes: Data on 13,940 Hospitalized Patients from the Spanish Nationwide SEMI-COVID-19 Registry

(1) Objectives: To describe the clinical characteristics and clinical course of hospitalized patients with COVID-19 and autoimmune diseases (ADs) compared to the general population. (2) Methods: We used information available in the nationwide Spanish SEMI-COVID-19 Registry, which retrospectively compiles data from the first admission of adult patients with COVID-19. We selected all patients with ADs included in the registry and compared them to the remaining patients. The primary outcome was all-cause mortality during admission, readmission, and subsequent admissions, and secondary outcomes were a composite outcome including the need for intensive care unit (ICU) admission, invasive and non-invasive mechanical ventilation (MV), or death, as well as in-hospital complications. (3) Results: A total of 13,940 patients diagnosed with COVID-19 were included, of which 362 (2.6%) had an AD. Patients with ADs were older, more likely to be female, and had greater comorbidity. On the multivariate logistic regression analysis, which involved the inverse propensity score weighting method, AD as a whole was not associated with an increased risk of any of the outcome variables. Habitual treatment with corticosteroids (CSs), age, Barthel Index score, and comorbidity were associated with poor outcomes. Biological disease-modifying anti-rheumatic drugs (bDMARDs) were associated with a decrease in mortality in patients with AD. (4) Conclusions: The analysis of the SEMI-COVID-19 Registry shows that ADs do not lead to a different prognosis, measured by mortality, complications, or the composite outcome. Considered individually, it seems that some diseases entail a different prognosis than that of the general population. Immunosuppressive/immunoregulatory treatments (IST) prior to admission had variable effects

Environmental gradients and the evolution of successional habitat specialization: A test case with 14 Neotropical forest sites

https://www.scopus.com/inward/record.url?eid=2-s2.0-84939570316&partnerID=40&md5=fcadae8e6c274e8b7efca96099304a7cSuccessional gradients are ubiquitous in nature, yet few studies have systematically examined the evolutionary origins of taxa that specialize at different successional stages. Here we quantify successional habitat specialization in Neotropical forest trees and evaluate its evolutionary lability along a precipitation gradient. Theoretically, successional habitat specialization should be more evolutionarily conserved in wet forests than in dry forests due to more extreme microenvironmental differentiation between early and late-successional stages in wet forest. We applied a robust multinomial classification model to samples of primary and secondary forest trees from 14 Neotropical lowland forest sites spanning a precipitation gradient from 788 to 4000 mm annual rainfall, identifying species that are old-growth specialists and secondary forest specialists in each site. We constructed phylogenies for the classified taxa at each site and for the entire set of classified taxa and tested whether successional habitat specialization is phylogenetically conserved. We further investigated differences in the functional traits of species specializing in secondary vs. old-growth forest along the precipitation gradient, expecting different trait associations with secondary forest specialists in wet vs. dry forests since water availability is more limiting in dry forests and light availability more limiting in wet forests. Successional habitat specialization is non-randomly distributed in the angiosperm phylogeny, with a tendency towards phylogenetic conservatism overall and a trend towards stronger conservatism in wet forests than in dry forests. However, the specialists come from all the major branches of the angiosperm phylogeny, and very few functional traits showed any consistent relationships with successional habitat specialization in either wet or dry forests. Synthesis. The niche conservatism evident in the habitat specialization of Neotropical trees suggests a role for radiation into different successional habitats in the evolution of species-rich genera, though the diversity of functional traits that lead to success in different successional habitats complicates analyses at the community scale. Examining the distribution of particular lineages with respect to successional gradients may provide more insight into the role of successional habitat specialization in the evolution of species-rich taxa