248 research outputs found
The influence of advection and diffusion on the time dependent response of tether particle based biosensors simulated with COMSOL Multiphysics
People, Texts and Artefacts: Cultural Transmission in the Norman Worlds of the Eleventh and Twelfth Centuries
This volume is based on two international conferences held in 2013 and 2014 at Ariano Irpino, and at Emmanuel College, Cambridge. It contains essays by leading scholars in the field. Like the conferences, the volume seeks to enhance interdisciplinary and international dialogue between those who work on the Normans and their conquests in northern and southern Europe in an original way. It has as its central theme issues related to cultural transfer, treated as being of a pan-European kind across the societies that the Normans conquered and as occurring within the distinct societies of the northern and southern conquests. These issues are also shown to be an aspect of the interaction between the Normans and the peoples they subjugated, among whom many then settled
2012 Screengrab International New Media Arts Award & Exhibition
Screengrab is an annual exhibition of screen based new media art curated from online submissions from around the world and submitted via the internet. The 2012 theme was, "Control".
The work in the exhibition represents the shortlisted entries for the Screengrab International New Media Arts Award sponsored by the School of Creative Arts (SoCA), James Cook University and the eMerge Media Space. The works for the inaugural award were curated by the SoCA Gallery Committee which is comprised of academic and professional staff
Serlo of Bayeux and England
After a short introduction highlighting Serlo’s ambiguous attitude to the English and its king in 1105-1106, I shall discuss three texts which link Serlo with England. First there is Serlo’s poem Defensio pro filiis presbyterorum of which the oldest copy is preserved (incompletely) in a manuscript of Exeter Cathedral c. 1100 (Cambridge CCC ms 190, p. 361). The first 59 lines, in a haphazard order, have survived and concentrate mainly on the sacrament of baptism, the fact that sons cannot be held responsible for the sins of their fathers and the legislators’ lack of attention for simony and homosexuality. Second, I will discuss Serlo’s poem ad Murielem, the versificatrix nun of Wilton (d. before 1113) which was written after Baudri of Bourgueil’s poem for her. Thirdly and briefly I will explore the implications of the suggestion, first raised by Edoardo D’Angelo, that the poem Septem maiores numeramus was written by Serlo for Queen Edith Matilda (d. 1118), perhaps as a contribution to one of her competitions organised for poets.Après une brève introduction mettant en évidence l’attitude ambiguë de Serlon envers les Anglais et leur roi dans les années 1105-1106, je présenterai trois textes qui évoquent les liens de Serlon avec l’Angleterre. Il s’agit d’abord du poème de Serlon Defensio pro filiis Presbyterorum, dont la plus ancienne copie est conservée (partiellement) dans un manuscrit de la Cathédrale d’Exeter daté des environs de 1100 (Cambridge CCC ms 190, p. 361). Les 59 premiers vers, conservés dans un ordre aléatoire, portent principalement sur le sacrement du baptême et sur le fait que les fils ne peuvent être tenus pour responsables des péchés de leurs pères et sur le manque d’attention porté par les législateurs aux questions de simonie et d’homosexualité. Ensuite, j’analyserai le poème ad Murielem, sur la religieuse versificatrice de Wilton († avant 1113), poème que Serlon écrivit après que Baudri de Bourgueil eut écrit celui qu’il consacra à cette religieuse. Enfin, brièvement, j’étudierai les implications de la suggestion, d’abord émise par Edoardo D’Angelo, selon laquelle le poème Septem maiores numeramus fut écrit par Serlon pour la reine Edith Matilda († 1118), peut-être comme une contribution à l’un des concours de poésie qu’elle organisa.Dopo una breve introduzione volta a mettere in evidenza l’atteggiamento ambiguo di Serlone verso gli Inglesi ed il loro re negli anni tra il 1105 e il 1106, presenterò tre testi che evocano i rapporti di Serlone con l’Inghilterra. Si tratta innanzitutto della Defensio pro filiis Presbyterorum, poesia di Serlone la cui copia più antica è conservata (parzialmente) in un manoscritto della Cattedrale di Exeter datato all’incirca al 1100 (Cambridge CCC ms 190, p. 361). I primi 59 versi, serbati in un ordine casuale, vertono principalmente sul sacramento del battesimo e sul fatto che i figli non possono essere considerati responsabili dei peccati dei loro padri e sulla mancata attenzione rivolta da parte dei legislatori alle questioni della simonia e dell’omosessualità . In seguito, analizzerò la poesia ad Murielem, sulla religiosa versificatrice di Wilton († prima del 1113), testo che Serlone compose dopo quello che Balderico di Bourgueil dedicò alla stessa monaca. Infine, studierò brevemente le implicazioni del suggerimento, proposto per la prima volta da Edoardo D’Angelo, secondo il quale la poesia Septem maiores numeramus fu scritta da Serlone per la regina Edith Matilda († 1118), forse come contributo per uno dei concorsi di poesia da lei organizzati
Les femmes dans l’histoire du duché de Normandie
Loin de conclure que les femmes normandes n’ont joué aucun rôle dans le processus de l’écriture de l’Histoire, je voudrais suggérer qu’elles ont pu s’impliquer de différentes manières dans l’histoire de leurs familles. Elles ont agi comme des « canaux de communication historique » entre les générations. Des femmes de l’aristocratie, s’occupant du passé, du présent et du futur, ont stimulé la production de récits historiques et prophétiques. Trois dossiers en particulier ont retenu mon attention : le don du château du Homme (Cotentin) de la comtesse Adeliza de Bourgogne aux religieuses de La Trinité de Caen en 1075 ; les deux versions du récit de la fondation de l’église de Saint-Martin d’Auchy de la fin du XIe siècle et le manuscrit Paris BnF lat. 5390 (Raoul Glaber, Vie de Guillaume de Volpiano ; Adson de Montier-en-Der, L’origine et du temps d’Antéchrist et la prophétie sibylline) copié entre 1060 et 1070.Instead of concluding that Norman women did not play any role in the process of writing history, I should like to suggest that there were other ways in which they could be involved with the history of their families. They acted as channels of historical knowledge between the generations. Aristocratic women, preoccupied with the past, the present and the future, stimulated the production of historical and prophetical narratives. Three dossiers in particular will be discussed here: the grant of the castle of Le Homme (Cotentin) by Countess Adeliza of Burgundy to the nuns of Holy Trinity at Caen in 1075, the two versions of the foundation narrative of the church of St Martin at Auchy dating to the late eleventh century, and manuscript Paris BN Lat. 5390 (Ralph Glaber, Life of William of Volpiano; Adso of Montier-en-Der, The Origin and Time of the Antichrist and the sibyline prophecy) copied between 1060 and 1070
Analysis of OSB Mat Stucture Made From Industrially Manufactured Strands Using Simulation Modeling
Industrially manufactured oriented strandboard (OSB) furnish was characterized by scanning images of a large number of individual strands and analyzing their shape properties. A Visual Basic macro in combination with commercially available image synthesis software was utilized to carry out the task of this analysis. The scanned images of these strands were used in a model that simulates the formation of layers within an OSB mat. These layers were simulated using three different orientation scenarios: random orientation. 100% strand alignment, and strand alignment based on industrial parameters. Information provided by the model includes the number and geometrical details of voids and strand overlap. Total void area for a mat is shown to be independant of strand orientation and the aspect ratio of strands. Interestingly, noticeable differences in the number, size, orientation, and shape factor of the individual voids, which make up the total area, were shown between various mat configurations
2009 Screengrab International New Media Arts Award and Exhibition
Screengrab is an annual exhibition of screen based new media art curated from online submissions from around the world and submitted via the internet. The 2009 theme was, "Intervention".
The work in the exhibition represents the shortlisted entries for the Screengrab International New Media Arts Award sponsored by the School of Creative Arts (SoCA), James Cook University and the eMerge Media Space. The works for the inaugural award were curated by the SoCA Gallery Committee which is comprised of academic and professional staff
Process and raw material control strategies to manage variability in charge variant species of a monoclonal antibody
Manufacturing lots of a monoclonal antibody (mAb) produced from a mammalian cell culture process showed increased variability in charge variant species. Root cause investigation uncovered production bioreactor pH and raw material lot-to-lot variability as potential factors affecting the levels of charge variant species. These factors were studied in a qualified 3L scale-down model representative of the large scale manufacturing process. Scale-down experiments confirmed the sensitivity of charge variants to bioreactor pH. Data mining from two manufacturing sites revealed differences in pH equipment and sample handling that contributed to the overall variability. An even greater magnitude of change was observed as a function of basal medium lot-to-lot variability. The variability was compounded due to the presence of hydrolysates in the basal medium. Peptide mapping was performed to check if differences between the samples with different levels of charge variant species could be observed. Results suggested that two different enzymatic modifications, C-terminal lysine clipping and C-terminal leucine amidation, were likely responsible for changes in the charge variants. Subsequently the effect of media components and trace metals such as manganese, copper, zinc and iron, were tested in high throughput scale-down systems using dose response experiments. Follow-up experiments were performed to evaluate the sensitivity of the process to trace metals. In summary, the two main causes of variability of charge species of this mAb were found to be bioreactor pH and trace metal concentration. Characterization of the antibody at the peptide level revealed mechanisms of formation of the charge variant species. We will present strategies for controlling product quality and increasing process robustness at large scale as a result of this work
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