Understanding Gender-Based Differences in Consumer E-Commerce Adoption

Despite the spread of e-commerce, few studies have investigated gender-based differences in the adoption of consumer-oriented electronic commerce. Theory and evidence from other domains indicates that such differences may exist. Using innovation diffusion theory as a framework, we empirically investigate whether the impact of beliefs regarding the characteristics of e-commerce and the trustworthiness of Web merchants on intentions to use e-commerce differ according to gender. Results indicate that such differences do exist. Perceived compatibility and visibility have greater impacts for women. In contrast, males\u27 use intentions are more driven by perceived relative advantage and result demonstrability. No differences were found for perceived ease of use and Web merchant trustworthiness

A Bayesian 3-D linear gravity inversion for complex density distributions: application to the Puysegur subduction system

We have developed a linear 3-D gravity inversion method capable of modelling complex geological regions such as subduction margins. Our procedure inverts satellite gravity to determine the best-fitting differential densities of spatially discretized subsurface prisms in a least-squares sense. We use a Bayesian approach to incorporate both data error and prior constraints based on seismic reflection and refraction data. Based on these data, Gaussian priors are applied to the appropriate model parameters as absolute equality constraints. To stabilize the inversion and provide relative equality constraints on the parameters, we utilize a combination of first and second order Tikhonov regularization, which enforces smoothness in the horizontal direction between seismically constrained regions, while allowing for sharper contacts in the vertical. We apply this method to the nascent Puysegur Trench, south of New Zealand, where oceanic lithosphere of the Australian Plate has underthrust Puysegur Ridge and Solander Basin on the Pacific Plate since the Miocene. These models provide insight into the density contrasts, Moho depth, and crustal thickness in the region. The final model has a mean standard deviation on the model parameters of about 17 kg m⁻³, and a mean absolute error on the predicted gravity of about 3.9 mGal, demonstrating the success of this method for even complex density distributions like those present at subduction zones. The posterior density distribution versus seismic velocity is diagnostic of compositional and structural changes and shows a thin sliver of oceanic crust emplaced between the nascent thrust and the strike slip Puysegur Fault. However, the northern end of the Puysegur Ridge, at the Snares Zone, is predominantly buoyant continental crust, despite its subsidence with respect to the rest of the ridge. These features highlight the mechanical changes unfolding during subduction initiation

Gender-Based Differences in Consumer E-Commerce Adoption

Among the many characteristics that impact the use of e-commerce, one that has received relatively little attention is gender. Extant evidence suggests that men and women differ in their beliefs regarding the use of information technology-related innovations, including e-commerce. However, less is known about how gender moderates the impact of various beliefs on behavioral intentions. In this study, we use a model derived from diffusion of innovations theory to examine gender differences in the degree to which various beliefs regarding e-commerce impact intentions to make purchases online. Results indicate that gender does moderate the influence of beliefs on use intentions in the context of consumer e-commerce. Specifically, our study finds that relative advantage is relatively more important for men and that compatibility is relatively more important for women. We explain why this may be true, discuss the implications of these findings and suggest several areas for future research

Strike-Slip Enables Subduction Initiation Beneath a Failed Rift: New Seismic Constraints From Puysegur Margin, New Zealand

Subduction initiation often takes advantage of previously weakened lithosphere and may preferentially nucleate along pre‐existing plate boundaries. To evaluate how past tectonic regimes and inherited lithospheric structure might lead to self‐sustaining subduction, we present an analysis of the Puysegur Trench, a young subduction zone with a rapidly evolving tectonic history. The Puysegur margin, south of New Zealand, has experienced a transformation from rifting to seafloor spreading to strike‐slip, and most recently to incipient subduction, all in the last ∼45 million years. Here we present deep‐penetrating multichannel reflection and ocean‐bottom seismometer tomographic images to document crustal structures along the margin. Our images reveal that the overriding Pacific Plate beneath the Solander Basin contains stretched continental crust with magmatic intrusions, which formed from Eocene‐Oligocene rifting between the Campbell and Challenger plateaus. Rifting was more advanced to the south, yet never proceeded to breakup and seafloor spreading in the Solander Basin as previously thought. Subsequent strike‐slip deformation translated continental crust northward causing an oblique collisional zone, with trailing ∼10 Myr old oceanic lithosphere. Incipient subduction transpired as oceanic lithosphere from the south forcibly underthrust the continent‐collision zone. We suggest that subduction initiation at the Puysegur Trench was assisted by inherited buoyancy contrasts and structural weaknesses that were imprinted into the lithosphere during earlier phases of continental rifting and strike‐slip along the plate boundary. The Puysegur margin demonstrates that forced nucleation along a strike‐slip boundary is a viable subduction initiation scenario and should be considered throughout Earth's history

Strike-slip Enables Subduction Initiation beneath a Failed Rift: New Seismic Constraints from Puysegur Margin, New Zealand

Subduction initiation often takes advantage of previously weakened lithosphere and may preferentially nucleate along pre-existing plate boundaries. To evaluate how past tectonic regimes and inherited lithospheric structure might lead to self-sustaining subduction, we present an analysis of the Puysegur Trench, a young subduction zone with a rapidly evolving tectonic history. The Puysegur margin, south of New Zealand, has experienced a transformation from rifting to seafloor spreading to strike-slip, and most recently to incipient subduction, all in the last ~45 million years. Here we present deep-penetrating multichannel reflection (MCS) and ocean-bottom seismometer (OBS) tomographic images to document crustal structures along the margin. Our images reveal that the overriding Pacific Plate beneath the Solander Basin contains stretched continental crust with magmatic intrusions, which formed from Eocene-Oligocene rifting between the Campbell and Challenger plateaus. Rifting was more advanced to the south, yet never proceeded to breakup and seafloor spreading in the Solander Basin as previously thought. Subsequent strike-slip deformation translated continental crust northward causing an oblique collisional zone, with trailing ~10 Myr old oceanic lithosphere. Incipient subduction transpired as oceanic lithosphere from the south forcibly underthrust the continent-collision zone. We suggest that subduction initiation at the Puysegur Trench was assisted by inherited buoyancy contrasts and structural weaknesses that were imprinted into the lithosphere during earlier phases of continental rifting and strike-slip along the plate boundary. The Puysegur margin demonstrates that forced nucleation along a strike-slip boundary is a viable subduction initiation scenario and should be considered throughout Earth's history

Differential Association of Gene Content Polymorphisms of Killer Cell Immunoglobulin-Like Receptors with Placental Malaria in HIV− and HIV+ Mothers

Pregnant women have abundant natural killer (NK) cells in their placenta, and NK cell function is regulated by polymorphisms of killer cell immunoglobulin-like receptors (KIRs). Previous studies report different roles of NK cells in the immune responses to placental malaria (PM) and human immunodeficiency virus (HIV-1) infections. Given these references, the aim of this study was to determine the association between KIR gene content polymorphism and PM infection in pregnant women of known HIV-1 status. Sixteen genes in the KIR family were analyzed in 688 pregnant Kenyan women. Gene content polymorphisms were assessed in relation to PM in HIV-1 negative and HIV-1 positive women, respectively. Results showed that in HIV-1 negative women, the presence of the individual genes KIR2DL1 and KIR2DL3 increased the odds of having PM, and the KIR2DL2/KIR2DL2 homozygotes were associated with protection from PM. However, the reverse relationship was observed in HIV-1 positive women, where the presence of individual KIR2DL3 was associated with protection from PM, and KIR2DL2/KIR2DL2 homozygotes increased the odds for susceptibility to PM. Further analysis of the HIV-1 positive women stratified by CD4 counts showed that this reverse association between KIR genes and PM remained only in the individuals with high CD4 cell counts but not in those with low CD4 cell counts. Collectively, these results suggest that inhibitory KIR2DL2 and KIR2DL3, which are alleles of the same locus, play a role in the inverse effects on PM and PM/HIV co-infection and the effect of KIR genes on PM in HIV positive women is dependent on high CD4 cell counts. In addition, analysis of linkage disequilibrium (LD) of the PM relevant KIR genes showed strong LD in women without PM regardless of their HIV status while LD was broken in those with PM, indicating possible selection pressure by malaria infection on the KIR genes

Intimate Partner Violence in Urban, Rural, and Remote Areas: An Investigation of Offense Severity and Risk Factors

This study compared the severity of intimate partner violence (IPV) and the relationship between risk factors for IPV and overall risk judgements of future IPV in urban, rural and remote areas. IPV risk assessments conducted by the Swedish police between 2010 and 2014 in urban (n = 564), rural (n = 456), and remote (n = 196) areas were examined. Rurality was associated with the severity of IPV reported, as well as the presence of risk factors and their relationship to overall risk judgements. Cases in remote areas included more severe IPV as well as more risk factors

Incipient subduction at the contact with stretched continental crust: The Puysegur Trench

A seismic Benioff zone and plate kinematics show Puysegur Trench south of New Zealand transitioning to subduction. Because the local structure and its influence on subduction initiation is poorly understood, we conducted a seismic survey with ocean bottom seismometers and multichannel seismic profiles. Our early results show that the overriding Pacific Plate beneath the Solander Basin is composed of block-faulted and thinned continental crust, and the inner trench wall of northern Puysegur Ridge is composed of folded and faulted sediment. The megathrust interface has been imaged and shows ∼500 m of downgoing, undisturbed sediments. Combining plate kinematic history with seismic velocity-inferred density, we show that the density difference across the plate boundary changed as oblique strike-slip plate motion juxtaposed dense oceanic crust with thinned continental crust. The density difference rapidly increased 18 to 15 Ma, coincident with subduction initiation, suggesting that compositional differences have a large influence on subduction initiation

Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3

Human tumors differ from normal tissues in their capacity to present Hsp70, the major stress-inducible member of the HSP70 family, on their plasma membrane. Membrane Hsp70 has been found to serve as a prognostic indicator of overall patient survival in leukemia, lower rectal and non small cell lung carcinomas. Why tumors, but not normal cells, present Hsp70 on their cell surface and the impact of membrane Hsp70 on cancer progression remains to be elucidated.Although Hsp70 has been reported to be associated with cholesterol rich microdomains (CRMs), the partner in the plasma membrane with which Hsp70 interacts has yet to be identified. Herein, global lipid profiling demonstrates that Hsp70 membrane-positive tumors differ from their membrane-negative counterparts by containing significantly higher amounts of globotriaoslyceramide (Gb3), but not of other lipids such as lactosylceramide (LacCer), dodecasaccharideceramide (DoCer), galactosylceramide (GalCer), ceramide (Cer), or the ganglioside GM1. Apart from germinal center B cells, normal tissues are Gb3 membrane-negative. Co-localization of Hsp70 and Gb3 was selectively determined in Gb3 membrane-positive tumor cells, and these cells were also shown to bind soluble Hsp70-FITC protein from outside in a concentration-dependent manner. Given that the latter interaction can be blocked by a Gb3-specific antibody, and that the depletion of globotriaosides from tumors reduces the amount of membrane-bound Hsp70, we propose that Gb3 is a binding partner for Hsp70. The in vitro finding that Hsp70 predominantly binds to artificial liposomes containing Gb3 (PC/SM/Chol/Gb3, 17/45/33/5) confirms that Gb3 is an interaction partner for Hsp70.These data indicate that the presence of Gb3 enables anchorage of Hsp70 in the plasma membrane of tumors and thus they might explain tumor-specific membrane localization of Hsp70