1,019 research outputs found
Reconsidering the future of Eastern Europe: The case of Czecho-Slovakia
Economic Reform;economic systems
From psychotherapy to emotional well being
This paper considers the relevance of philosophy to psychotherapy. It traces the progression of early western philosophy in its approach to human emotions and considers how this is mirrored in current psychotherapeutic practice. It argues that psychotherapists have much to learn from philosophy and that a clear understanding of life events and issues is essential for doing good psychotherapy
Predictors of Surgical Margin Following Breast-Conserving Surgery: A Large Population-Based Cohort Study
Background: The purpose of this retrospective, population-based, cohort study was to identify patient and tumor characteristics that are associated with a high risk of tumor-positive margins after breast-conserving surgery (BCS) to optimize preoperative counseling. Methods: All patients with invasive breast cancer (IBC) reported according to the synoptic reporting module in the Dutch Pathology Registry between 2009 and 2015 were included (n = 42.048 cases). Data extraction included age, type of surgery, several tumor characteristics, and resection margin status according to the Dutch indications for re-excision (free, focally positive, or more than focally positive). Univariate and multivariate tests were used to determine the association between clinicopathological features and margin status, restricted to patients with BCS. Results: Of 42,048 cases, a total of 25,315 cases (60.2 %) with IBC underwent BCS. Of these patients, 2578 patients (10.2 %) had focally positive resection margins and 1665 (6.6 %) had more than focally positive resection margins. By univariate analysis, the following features were significantly associated with involved margins: age 2 cm, intermediate- and high-grade, positive ER status, positive Her2 status, angio-invasion, and the presence/extent of a ductal carcinoma in situ (DCIS) component. In multivariate logistic regression, the variables with the strongest association with involved margins (OR > 2) were multifocality, lobular subtype, large tumor size, and the presence of DCIS. Conclusions: Several clinicopathologic features are associated with involved resection margins after BCS for IBC. Assessment of these features preoperatively could be used to optimize preoperative counseling
The Integrand Reduction of One- and Two-Loop Scattering Amplitudes
The integrand-level methods for the reduction of scattering amplitudes are
well-established techniques, which have already proven their effectiveness in
several applications at one-loop. In addition to the automation and refinement
of tools for one-loop calculations, during the past year we observed very
interesting progress in developing new techniques for amplitudes at two- and
higher-loops, based on similar principles. In this presentation, we review the
main features of integrand-level approaches with a particular focus on
algebraic techniques, such as Laurent series expansion which we used to improve
the one-loop reduction, and multivariate polynomial division which unveils the
structure of multi-loop amplitudes.Comment: 7 pages, v2: fixed typos, added references. Presented at "Loops and
Legs in Quantum Field Theory", Wernigerode, Germany, 15-20 April 201
Multi-leg One-loop Massive Amplitudes from Integrand Reduction via Laurent Expansion
We present the application of a novel reduction technique for one-loop
scattering amplitudes based on the combination of the integrand reduction and
Laurent expansion. We describe the general features of its implementation in
the computer code NINJA, and its interface to GoSam. We apply the new reduction
to a series of selected processes involving massive particles, from six to
eight legs.Comment: v3: 39 pages, minor typos and one benchmark point correcte
NLO QCD corrections to Higgs boson production in association with a top quark pair and a jet
We present the calculation of the cross section for Higgs boson production in
association with a top quark pair plus one jet, at next-to-leading-order (NLO)
accuracy in QCD. All mass dependence is retained without recurring to any
approximation. After including the complete NLO QCD corrections, we observe a
strong reduction in the scale dependence of the result. We also show
distributions for the invariant mass of the top quark pair, with and without
the additional jet, and for the transverse momentum and the pseudorapidity of
the Higgs boson. Results for the virtual contributions are obtained with a
novel reduction approach based on integrand decomposition via Laurent
expansion, as implemented in the library Ninja. Cross sections and differential
distributions are obtained with an automated setup which combines the GoSam and
Sherpa frameworks.Comment: 5 pages, 5 figures. v3: corrected benchmark point in the appendi
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