Reconsidering the future of Eastern Europe: The case of Czecho-Slovakia

Economic Reform;economic systems

From psychotherapy to emotional well being

This paper considers the relevance of philosophy to psychotherapy. It traces the progression of early western philosophy in its approach to human emotions and considers how this is mirrored in current psychotherapeutic practice. It argues that psychotherapists have much to learn from philosophy and that a clear understanding of life events and issues is essential for doing good psychotherapy

Predictors of Surgical Margin Following Breast-Conserving Surgery: A Large Population-Based Cohort Study

Background: The purpose of this retrospective, population-based, cohort study was to identify patient and tumor characteristics that are associated with a high risk of tumor-positive margins after breast-conserving surgery (BCS) to optimize preoperative counseling. Methods: All patients with invasive breast cancer (IBC) reported according to the synoptic reporting module in the Dutch Pathology Registry between 2009 and 2015 were included (n = 42.048 cases). Data extraction included age, type of surgery, several tumor characteristics, and resection margin status according to the Dutch indications for re-excision (free, focally positive, or more than focally positive). Univariate and multivariate tests were used to determine the association between clinicopathological features and margin status, restricted to patients with BCS. Results: Of 42,048 cases, a total of 25,315 cases (60.2 %) with IBC underwent BCS. Of these patients, 2578 patients (10.2 %) had focally positive resection margins and 1665 (6.6 %) had more than focally positive resection margins. By univariate analysis, the following features were significantly associated with involved margins: age 2 cm, intermediate- and high-grade, positive ER status, positive Her2 status, angio-invasion, and the presence/extent of a ductal carcinoma in situ (DCIS) component. In multivariate logistic regression, the variables with the strongest association with involved margins (OR > 2) were multifocality, lobular subtype, large tumor size, and the presence of DCIS. Conclusions: Several clinicopathologic features are associated with involved resection margins after BCS for IBC. Assessment of these features preoperatively could be used to optimize preoperative counseling

The Integrand Reduction of One- and Two-Loop Scattering Amplitudes

The integrand-level methods for the reduction of scattering amplitudes are well-established techniques, which have already proven their effectiveness in several applications at one-loop. In addition to the automation and refinement of tools for one-loop calculations, during the past year we observed very interesting progress in developing new techniques for amplitudes at two- and higher-loops, based on similar principles. In this presentation, we review the main features of integrand-level approaches with a particular focus on algebraic techniques, such as Laurent series expansion which we used to improve the one-loop reduction, and multivariate polynomial division which unveils the structure of multi-loop amplitudes.Comment: 7 pages, v2: fixed typos, added references. Presented at "Loops and Legs in Quantum Field Theory", Wernigerode, Germany, 15-20 April 201

Multi-leg One-loop Massive Amplitudes from Integrand Reduction via Laurent Expansion

We present the application of a novel reduction technique for one-loop scattering amplitudes based on the combination of the integrand reduction and Laurent expansion. We describe the general features of its implementation in the computer code NINJA, and its interface to GoSam. We apply the new reduction to a series of selected processes involving massive particles, from six to eight legs.Comment: v3: 39 pages, minor typos and one benchmark point correcte

NLO QCD corrections to Higgs boson production in association with a top quark pair and a jet

We present the calculation of the cross section for Higgs boson production in association with a top quark pair plus one jet, at next-to-leading-order (NLO) accuracy in QCD. All mass dependence is retained without recurring to any approximation. After including the complete NLO QCD corrections, we observe a strong reduction in the scale dependence of the result. We also show distributions for the invariant mass of the top quark pair, with and without the additional jet, and for the transverse momentum and the pseudorapidity of the Higgs boson. Results for the virtual contributions are obtained with a novel reduction approach based on integrand decomposition via Laurent expansion, as implemented in the library Ninja. Cross sections and differential distributions are obtained with an automated setup which combines the GoSam and Sherpa frameworks.Comment: 5 pages, 5 figures. v3: corrected benchmark point in the appendi