Formación y competencias del podólogo a nivel internacional

Treball Final de Grau de Podologia, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, curs: 2016-2017, Tutor: Virginia Novel MartíDesde sus inicios en el antiguo Egipto, la podología ha ido evolucionando a lo largo de los siglos hasta el día de hoy, aunque de maneras muy distintas dependiendo de los hábitos culturales de cada región geográfica. De este modo, llegamos a una actualidad con grandes diferencias en el desarrollo de la profesión entre un país y otro. En este contexto, los objetivos de este estudio pretenden: 1) Determinar la situación de la podología a nivel de formación académica, legislación y competencias profesionales, en los países miembros de la FIP (Federación Internacional de Podólogos). 2) Valorar qué campos de trabajo destacan en cada país. Y una vez establecidas esas diferencias, 3) Comparar la situación actual de la podología en España con la del resto de países para valorar el lugar que ocupa a nivel mundial. Para alcanzar estos objetivos se inicia una búsqueda bibliográfica, mayormente de literatura no convencional, a través de páginas web de instituciones gubernamentales y mediante un cuestionario enviado a representantes de la podología de sus respectivos países. Después del estudio de la formación académica en los diferentes países y de sus competencias, se encuentran diferencias destacables, no siempre interrelacionadas entre ellas, ante las cuales sería interesante trabajar por conseguir un currículum académico y competencial más homogéneo a nivel internacional

Holocene relative mean sea-level changes in the Wadden Sea area, northern Netherlands

Although the Netherlands has a long tradition of sea-level research, no Holocene relative sea-level curve is available for the north of the country. Previous studies hypothesized that the relative sea-level reconstruction for the western Netherlands is also valid for the northern part of the country. However, glacial isostatic adjustment (GIA) models predict a lower and steeper relative sea-level curve because of greater postglacial isostatic subsidence. Long-term data of relative sea-level change are important to inform GIA models and understand postglacial vertical land motion related to the rebound of Fennoscandia and neotectonic activity. We compiled and evaluated a set of basal peat radiocarbon dates to reconstruct the Holocene relative mean sea-level rise in the Dutch Wadden Sea area. For the early Holocene, this reconstruction is lower than the western Netherlands curve. After 6400 cal a BP, the curve for the Wadden Sea is statistically indistinguishable from that for the western Netherlands, a result that conflicts with GIA model results. It remains to be investigated whether the problem lies with the GIA model predictions or with the quality of the available data. Additional basal peat radiocarbon dates from suitable sites should be collected to further resolve this problem

Live-cell imaging of sterculic acid - a naturally occurring 1,2-cyclopropene fatty acid - by bioorthogonal reaction with turn-on tetrazine-fluorophore conjugates

In the field of lipid research, bioorthogonal chemistry has made the study of lipid uptake and processing in living systems possible, whilst minimising biological properties arising from detectable pendant groups. To allow the study of unsaturated free fatty acids in live cells, we here report the use of sterculic acid, a 1,2-cyclopropene-containing oleic acid analogue, as a bioorthogonal probe. We show that this lipid can be readily taken up by dendritic cells without toxic side effects, and that it can subsequently be visualised using an inverse electron-demand Diels-Alder reaction with quenched tetrazine-fluorophore conjugates. In addition, the lipid can be used to identify changes in protein oleoylation after immune cell activation. Finally, this reaction can be integrated into a multiplexed bioorthogonal reaction workflow by combining it with two sequential copper-catalysed Huisgen ligation reactions. This allows for the study of multiple biomolecules in the cell simultaneously by multimodal confocal imaging.NWOERC-CoG 865175Molecular PhysiologyBio-organic Synthesi

Reconstructing the accumulation history of a saltmarsh sediment core: which age-depth model is best?

Saltmarsh-based reconstructions of relative sea-level (RSL) change play a central role in current efforts seeking to quantify the relationship between climate and sea-level rise. The development of an accurate chronology is pivotal, since errors in age-depth relationships will propagate to the final record as alterations in both the timing and magnitude of reconstructed change. A range of age-depth modelling packages are available but differences in their theoretical basis and practical operation mean contrasting accumulation histories can be produced from the same dataset. We compare the performance of five age-depth modelling programs (Bacon, Bchron, Bpeat, Clam and OxCal) when applied to the kinds of data used in high resolution, saltmarsh-based RSL reconstructions. We investigate their relative performance by comparing modelled accumulation curves against known age-depth relationships generated from simulated stratigraphic sequences. Bpeat is particularly sensitive to non-linearities which, whilst maximising the detection of small rate changes, has the potential to generate spurious variations, particularly in the last 400 years. Bacon generally replicates the pattern and magnitude of change but with notable offsets in timing. Bchron and OxCal successfully constrain the known accumulation history within their error envelopes although the best-fit solutions tend to underestimate the magnitude of change. The best-fit solutions of Clam generally replicate the timing and magnitude of changes well, but are sensitive to the underlying shape of the calibration curve, performing poorly where plateaus in atmospheric 14C concentration exist. We employ an ensemble of age-depth models to reconstruct a 1500 year accumulation history for a saltmarsh core recovered from Connecticut, USA based on a composite chronology comprising 26 AMS radiocarbon dates, 210Pb, 137Cs radionuclides and an historical pollen chronohorizon. The resulting record reveals non-linear accumulation during the late Holocene with a marked increase in rate around AD1800. With the exception of the interval between AD1500 and AD1800, all modelsproduce accumulation curves that agree to within ~10 cm at the century-scale. The accumulation rate increase around AD1800 is associated with the transition from a radiocarbon-based to a 210Pb dominated chronology. Whilst repeat analysis excluding the 210Pb data alters the precise timing and magnitude of this acceleration, a shift to faster accumulation compared to the long-term rate is a robust feature of the record and not simply an artefact of the switch in dating methods. Simulation indicates that a rise of similar magnitude to the post-AD1800 increase (detrended increase of ~16 cm) is theoretically constrained and detectable within the radiocarbon-dated portion of the record. The absence of such a signal suggests that the recent rate of accumulation is unprecedented in the last 1500 years. Our results indicate that reliable (sub)century-scale age-depth models can be developed from saltmarsh sequences, and that the vertical uncertainties associated with them translate to RSL reconstruction errors that are typically smaller than those associated with the most precise microfossil-based estimates of palaeomarsh-surface elevation