MaB-flocs for a more sustainable wastewater treatment

Conventional wastewater treatment with activated sludge has a large carbon footprint, high aeration rates are combined with CO2 emission from bacteria. By using micro-algal bacterial flocs (MaB-flocs), CO2 could be captured within the biomass and oxygen could be produced in situ. In order to maximize this photosynthetic aeration and CO2 mitigation, we investigated whether inorganic carbon could alter the algae/bacteria ratio while keeping a good removal performance and settleability of the MaB-flocs. Therefore, three illuminated sequencing batch reactors with MaB-flocs were fed with synthetic wastewater enriched with 84.2, 42.1 and 0 mg L-1 C-KHCO3 supplemented with 0, 42.1, 84.2 mg L-1 C-sucrose, respectively, representing the inorganic carbon source compared to an organic carbon source. Bicarbonate significantly increased the chlorophyll a concentration of the MaB-flocs, but only poor settling flocs could be obtained causing a high turbidity of the effluent. Moreover, significant lower nitrogen removal efficiencies were measured feeding bicarbonate compared to sucrose and the pH increased (9.5). Sucrose benefited a good reactor performance and showed a good settleability of MaB-flocs. Despite the lower chlorophyll a concentration of the biomass and the lower in situ oxygen concentration, average soluble COD removal efficiencies of 95 % were achieved with sucrose. Furthermore sucrose was successful in containing the optimal pH at 7. This study shows the importance of the carbon source for a good reactor performance. As a consequence, the inorganic/organic carbon ratio of the wastewater should be taken into account when algal bacterial reactors are used for wastewater treatment

Academic staff on their engagement with curriculum internationalisation:an organisational change perspective

Studies about curriculum internationalisation in higher education frequently report poor academic staff engagement hindering implementation in practice. However, such research does not consider the organisational context in which academics operate. This research applies an organisational change perspective to explore how the context affects the process of engagement and implementation and what to change (content). In a comparative case study of four disciplinary contexts in a West-European university from 2012 to 2020, we disclose the perceptions and experiences of twenty-nine academic staff through in-depth interviews. The academics explain how multiple contextual tensions and inadequate resource management complicate their engagement with curriculum internationalisation. Still, they also reveal evidence of many achievements and strong individual drivers with curriculum internationalisation. Our findings show how disciplinary contextual influences and dynamics create specific perceptions and experiences of curriculum internationalisation in each study programme. This article presents a comprehensive framework of organisational change to explain and facilitate academic staff engagement with curriculum internationalisation in disciplinary communities.</p

Human papillomavirus clade A9 specific cellular immunity during the natural course of disease

The immune system plays an important role in the balance between viral clearance and viral persistence in HPV related (pre)malignant lesions. In this thesis, we analyzed HPV clade A9-specific T-cell responses in relation to virological and clinical outcome to gain further insight into HPV-specific cellular immunity in relation to the natural course of disease. In depth analysis of cellular immune responses against the E6 antigen of HPV16 and the closely related members of clade A9 (HPV31, 33, 35, 52 and 58) showed us that HPV-specific cross-reactive CD4+ T cells are rare and unlikely to mediate cross protection (chapter 2). The clinical course of cervical HPV infection and HPV-specific immune responses in prospective studies are described in chapter 4 and 5. In those chapters, a strong correlation is observed between a persistent HPV infection or progressive disease and the lack or failure of a type-specific immune response (>90% of the cases). No correlation is detected between HPV type-specific cellular immune responses and virological clearance of the infection and HPV type-specific immunity may be associated with clearance of a cervical HPV induced lesion (chapter 4 and 5). Interestingly, a statistically significant trend could be detected between the presence of a type-specific immunity (HPV16E2) and regression of a low-grade lesion (chapter 5). A similar, but - due to small number of patients __ not statistically significant trend was observed in chapter 4. Together, this suggests that the local innate immune system might play a role in the clearance of transient infections, whereas the cellular immune response can play a role in regression of histologically proven HPV induced lesions. Detection of HPV16 type-specific cellular immune responses in vivo, by the use of a DTH skin test, confirmed that cellular immune responses in healthy subjects consist of both HPV-specific CD4+ Th1/Th2 and CD8+ T cells (chapter 3).Bronovo Research Fonds, GlaxoSmithKline, ISA Pharmaceuticals, J.E. Jurriaanse Stichting, Sanofi Pasteur MSDUBL - phd migration 201

An Organizational Change Perspective for the Curriculum Internationalization Process:Bridging the Gap between Strategy and Implementation

Following a rapidly changing external environment, internationalization has become an institutional phenomenon with strategic relevance for universities worldwide. However, the frequently reported gap between theory and practice remains. Engaging staff and achieving successful organizational implementation appears increasingly problematic with more stakeholders and disciplines involved. This study explores the long-time gap between strategy and implementation with Pettigrew's organizational change framework (1987). We conducted a systematic scoping literature review of articles about curriculum internationalization (N = 325) published in English in peer-reviewed journals between 2000 and 2022. Our study demonstrates that the organizational change perspective provides guidelines to improve and facilitate the process. Based on an organizational change perspective we developed a comprehensive framework that may contribute to more effective strategies for staff engagement and meaningful implementation outcomes for curriculum internationalization in higher education.<br/

Prevalence of Arcobacter species among humans, Belgium, 2008-2013

We examined fecal samples from 6,774 patients with enteritis in Belgium, 2008–2013. Members of the genus Arcobacter were the fourth most common pathogen group isolated, and the isolation rate was higher than previously reported. Culturing Arcobacter in a microbiology laboratory is feasible and should thus be tested for in cases of diarrheal disease

What Happens in Vegas Stays on TripAdvisor? A Theory and Technique to Understand Narrativity in Consumer Reviews

Many consumers base their purchase decisions on online consumer reviews. An overlooked feature of these texts is their narrativity: the extent to which they tell a story. The authors construct a new theory of narrativity to link the narrative content and discourse of consumer reviews to consumer behavior. They also develop from scratch a computerized technique that reliably determines the degree of narrativity of 190,461 verbatim, online consumer reviews and validate the automated text analysis with two controlled experiments. More transporting (i.e., engaging) and persuasive reviews have better developed characters and events as well as more emotionally changing genres and dramatic event orders. This interdisciplinary, multimethod research should help future researchers (1) predict how narrativity affects consumers’ narrative transportation and persuasion, (2) measure the narrativity of large digital corpora of textual data, and (3) understand how this important linguistic feature varies along a continuum