The preburning condition of Chalcolithic cremated human remains from the Perdigoes enclosures (Portugal)

The Iberian Chalcolithic displayed a remarkable variety of funerary practices, which has been related to interpopulation differences, intrapopulation social-cultural differences, and complex multistage funerary rituals. Perdigoes, a Chalcolithic set of ditched enclosures, reflects such diversity including a wide array of funerary practices. Among those practices is cremation, which, despite relatively rare, is represented in different structures in Perdigoes. One of these structures (Pit 40) presents an unparalleled high minimum number of individuals (n = 240), contrasting with nearby and coeval structures. In this study, we analyse heat-induced bone changes and other archaeothanatological variables to tentatively assess the preburning condition of the human remains. The results of Pit 40 are also compared with other comparable contexts to assess if this unique context presents further funerary differences relative to those other contexts in, for example, body processing. Our results suggest preferential cremation of fleshed human remains, but burning of at least a minority of skeletonised remains and deposition of possibly unburned remains also likely occurred. Body processing appears to be comparable with that of the cremation contexts of Perdigoes but contrasts with that of another nearby context (Dolmen of Olival da Pega 2b) in which burned bones were also found.Portuguese Foundation for Science and TechnologyPortuguese Foundation for Science and Technology [PEst-OE/SADG/UI0283/2013, POCI-01-0145-FEDER-016766, PTDC/EPH-ARQ/0798/2014, PTDC/IVC-ANT/1201/2014, SFRH/BPD/84268/2012]info:eu-repo/semantics/publishedVersio

Field analysis of the deterioration after some years of use of four insect-proof screens utilized in Mediterranean greenhouses

The installation of insect-proof screens on greenhouse vents is one of the principal methods of protection against harmful insects for crops. Their main disadvantage lies on their negative effects on natural ventilation and greenhouse microclimate, which have been the focus of studies by several authors. However, few works have analysed the effect of accumulated dust and dirt on these screens. The present study has analysed four anti-insect screens, comparing their geometric characteristics before installation and after three to four years of use. Two negative effects have been observed and quantified: deterioration of the threads that make up the screen and reduction of porosity due to accumulated dirt in the pores. This deterioration over time gives leads to a mean increase in thread diameter of 3.1%, as well to a mean decrease in the pore size of 6.2% and 2.3% in the weft (Lpx) and the warp (Lpy), respectively. In fact, the insect-proof screen porosity (φ) decreased due to the deterioration of the threads by an average of 6.5%, in addition to an average 20.3% reduction due to the accumulation of dirt in the pores, making a total reduction in porosity of 26.8%. This decrease in porosity leads to lower greenhouse ventilation rates, and is therefore detrimental for the greenhouse microclimate. Consequently, it is recommended that insect-proof screens in arid areas such as Almería (Spain), with abundant dust suspended in the atmosphere, be washed monthly using water sprayed at high pressure

Antibacterial TAP-mimic electrospun polymer scaffold: effects on P. gingivalis-infected dentin biofilm

OBJECTIVES: This study sought to investigate, in vitro, the effects of a recently developed triple antibiotic paste (TAP)-mimic polymer nanofibrous scaffold against Porphyromonas gingivalis-infected dentin biofilm. MATERIALS AND METHODS: Dentin specimens (4 × 4 × 1 mm(3)) were prepared from human canines. The specimens were sterilized, inoculated with P. gingivalis (ATCC 33277), and incubated for 1 week to allow for biofilm formation. Infected dentin specimens were exposed for 3 days to the following treatments: antibiotic-free polydioxanone scaffold (PDS, control), PDS + 25 wt% TAP [25 mg of each antibiotic (metronidazole, ciprofloxacin, and minocycline) per mL of the PDS polymer solution], or a saturated TAP-based solution (50 mg of each antibiotic per mL of saline solution). In order to serve as the negative control, infected dentin specimens were left untreated (bacteria only). To determine the antimicrobial efficacy of the TAP-mimic scaffold, a colony-forming unit (CFU) per milliliter (n = 10/group) measurement was performed. Furthermore, additional specimens (n = 2/group) were prepared to qualitatively study biofilm inhibition via scanning electron microscopy (SEM). Statistics were performed, and significance was set at the 5% level. RESULTS: Both the TAP-mimic scaffold and the positive control (TAP solution) led to complete bacterial elimination, differing statistically (p < 0.05) from the negative control group (bacteria only). No statistical differences were observed for CFU per milliliter data between antibiotic-free scaffolds (2.7 log10 CFU/mL) and the negative control (5.9 log10 CFU/mL). CONCLUSIONS: The obtained data revealed significant antimicrobial properties of the novel PDS-based TAP-mimic scaffold against an established P. gingivalis-infected dentin biofilm. CLINICAL RELEVANCE: Collectively, the data suggest that the proposed nanofibrous scaffold might be used as an alternative to the advocated clinical gold standard (i.e., TAP) for intracanal disinfection prior to regenerative endodontics

Chronic mercury exposure in Late Neolithic/Chalcolithic populations in Portugal from the cultural use of cinnabar

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/155748/1/Emslie_et_al_2015_Chronic_mercury.pd

20Ne+76Ge elastic and inelastic scattering at 306 MeV

Background: Double charge exchange (DCE) nuclear reactions have recently attracted much interest as tools to provide experimentally driven information about nuclear matrix elements of interest in the context of neutrinoless double- β decay. In this framework, a good description of the reaction mechanism and a complete knowledge of the initial and final-state interactions are mandatory. Presently, not enough is known about the details of the optical potentials and nuclear response to isospin operators for many of the projectile-target systems proposed for future DCE studies. Among these, the 20 Ne + 76 Ge DCE reaction is particularly relevant due to its connection with 76 Ge double- β decay. Purpose: We intend to characterize the initial-state interaction for the 20 Ne + 76 Ge reactions at 306 MeV bombarding energy and determine the optical potential and the role of the couplings between elastic channel and inelastic transitions to the first low-lying excited states. Methods: We determine the experimental elastic and inelastic scattering cross-section angular distributions, compare the theoretical predictions by adopting different models of optical potentials with the experimental data, and evaluate the coupling effect through the comparison of the distorted-wave Born approximation calculations with the coupled channels ones. Results: Optical models fail to describe the elastic angular distribution above the grazing angle ( ≈ 9.4 ∘ ). A correction in the geometry to effectively account for deformation of the involved nuclear systems improves the agreement up to about 14 ∘ . Coupled channels effects are crucial to obtain good agreement at large angles in the elastic scattering cross section. Conclusions: The analysis of elastic and inelastic scattering data turned out to be a powerful tool to explore the initial and final-state interactions in heavy-ion nuclear reactions at high transferred momenta.European Research Council (ERC) de la Unión Europea. Programa de investigación e innovación Horizonte 2020. 714625 y 654002Ministerio de Economía y Competitividad de España y Fondos FEDER. FIS2017-88410-

Data acquisition software for the CMS strip tracker

The CMS silicon strip tracker, providing a sensitive area of approximately 200 m2 and comprising 10 million readout channels, has recently been completed at the tracker integration facility at CERN. The strip tracker community is currently working to develop and integrate the online and offline software frameworks, known as XDAQ and CMSSW respectively, for the purposes of data acquisition and detector commissioning and monitoring. Recent developments have seen the integration of many new services and tools within the online data acquisition system, such as event building, online distributed analysis, an online monitoring framework, and data storage management. We review the various software components that comprise the strip tracker data acquisition system, the software architectures used for stand-alone and global data-taking modes. Our experiences in commissioning and operating one of the largest ever silicon micro-strip tracking systems are also reviewed

Healthcare students’ perceptions about their role, confidence and competence to deliver brief public health interventions and advice

Background Public health improvement has long been an important focus for the United Kingdom Department of Health. The Allied Health Professions (AHP) Federation has 84,000 members, such a large number of AHP professionals should play a role in public health initiatives, but it is not clear if they or the AHP students who will be the future healthcare workforce feel themselves equipped to do so. Our aim was to understand the perceptions of AHP students about their role in delivering public health advice. Methods AHP students were recruited in one teaching university from different departments. Participants were final year AHP students who had completed all clinical placements related to their course. All students were emailed an invitation to participate, and those interested were asked to contact the researchers to participate in one of several focus groups. Data were recorded, transcribed, and analysed using framework analysis by two independent researchers. Results Nineteen students were recruited and participated in four focus groups. The main themes produced by the data analysis were: understanding of public health issues, perceptions of their role in this, challenges and opportunities to develop a public health role, and preparation for a public health role. Conclusions AHP students felt that they had a role in public health advice-giving, but barriers to providing this advice included their own lack of confidence and knowledge, time, and the environment of the clinical placement. They considered that there should be more teaching on public health issues, and that these should feature in both the curriculum and on clinical placement

The promoter polymorphism -232C/G of the PCK1 gene is associated with type 2 diabetes in a UK-resident South Asian population

Background: The PCK1 gene, encoding cytosolic phosphoenolpyruvate carboxykinase (PEPCK-C), has previously been implicated as a candidate gene for type 2 diabetes (T2D) susceptibility. Rodent models demonstrate that over-expression of Pck1 can result in T2D development and a single nucleotide polymorphism (SNP) in the promoter region of human PCK1 (-232C/G) has exhibited significant association with the disease in several cohorts. Within the UK-resident South Asian population, T2D is 4 to 6 times more common than in indigenous white Caucasians. Despite this, few studies have reported on the genetic susceptibility to T2D in this ethnic group and none of these has investigated the possible effect of PCK1 variants. We therefore aimed to investigate the association between common variants of the PCK1 gene and T2D in a UK-resident South Asian population of Punjabi ancestry, originating predominantly from the Mirpur area of Azad Kashmir, Pakistan. \ud \ud Methods: We used TaqMan assays to genotype five tagSNPs covering the PCK1 gene, including the -232C/G variant, in 903 subjects with T2D and 471 normoglycaemic controls. \ud \ud Results: Of the variants studied, only the minor allele (G) of the -232C/G SNP demonstrated a significant association with T2D, displaying an OR of 1.21 (95% CI: 1.03 - 1.42, p = 0.019). \ud \ud Conclusion: This study is the first to investigate the association between variants of the PCK1 gene and T2D in South Asians. Our results suggest that the -232C/G promoter polymorphism confers susceptibility to T2D in this ethnic group. \ud \ud Trial registration: UKADS Trial Registration: ISRCTN38297969

Numerical and techno-economic analysis of batch annealing performance improvements in tinplate manufacturing

The present study examines the performance improvement in the batch annealing process used in tinplate manufacturing by enhancing the heat transfer towards the steel coils and altering annealing cycle parameters. Presently, the heat transfer in the furnace is non-uniform, resulting in non-uniform temperature profiles and recrystallisation inside the coils, affecting the final coated steel quality. This study modelled a current furnace and four improvement proposals utilising transient computational fluid dynamics, to produce coil temperature profiles and rank the cases by the highest coil temperature uniformity achieved at the end of soaking. By increasing the soaking temperature and time, as well as the coiling tension before annealing and altering the coil size, the aim was to achieve higher and more uniform coil temperatures that could ensure successful recrystallisation with less defects, especially at the cold spot area in the middle of the coil. Then, a techno-economic analysis compared the cost-effectiveness of the scenarios based on the associated costs and the improvement in the scratching defects of the batch-annealed steel. Overall, most cases exhibited positive results regarding temperature uniformity enhancement, but increasing the coiling tension was considered the most promising option, due to the combination of a large defect reduction potential and cost savings per cycle