Problematiche e complessità di genere nelle discipline del libro

The reflection, dedicated to the analysis from a gender perspective of three aspects of the disciplines of the book (profession, semantic cataloging and history of the book), is part of the broader context of critical librarianship, and intends to approach these issues with the awareness that it is an unavoidably unsystematic introduction due to the complexity and breadth of the discussion. However, it was deemed necessary to open a debate or at least ask the question because in Italy these aspects have not yet been dealt with systematically and organically and are discussed marginally and in conflict, without being able to arrive at a synthesis of meaning that accepts and re-elaborate the social processes that have been going on for years and the requests coming from the communities that express a way of being and feeling complementary to the canonical one of the masculine.La riflessione, dedicata all’analisi in un’ottica di genere di tre aspetti delle discipline del libro (professione, catalogazione semantica e storia del libro), si colloca nel più ampio ambito della biblioteconomia critica e intende approcciare queste tematiche con la consapevolezza che si tratta di un’introduzione inevitabilmente non sistematica per la complessità e l’ampiezza della discussione. Tuttavia, si è ritenuto necessario aprire un dibattito o quantomeno porre la questione poiché in Italia tali aspetti non sono stati ancora affrontati con sistematicità e organicità e vengono dibattuti marginalmente e conflittualmente, senza che si riesca a giungere a una sintesi di senso che accolga e rielabori i processi sociali ormai in atto da anni e le istanze provenienti dalle comunità che esprimono un modo di essere e di sentire complementare a quello canonico del maschile

Initial-boundary value problems for nearly incompressible vector fields, and applications to the Keyfitz and Kranzer system

We establish existence and uniqueness results for initial boundary value problems with nearly incompressible vector fields. We then apply our results to establish well-posedness of the initial-boundary value problem for the Keyfitz and Kranzer system of conservation laws in several space dimensions

Optimality of integrability estimates for advection-diffusion equations

We discuss Lp integrability estimates for the solution u of the advection–diffusion equation ∂tu+div(bu)=Δu, where the velocity field b∈LrtLqx. We first summarize some classical results proving such estimates for certain ranges of the exponents r and q. Afterwards we prove the optimality of such ranges by means of new original examples

Recent results on the singular local limit for nonlocal conservation laws

We provide an informal overview of recent developments concerning the singular local limit of nonlocal conservation laws. In particular, we discuss some counterexamples to convergence and we highlight the role of numerical viscosity in the numerical investigation of the nonlocal-to-local limit. We also state some open questions and describe recent related progress

Half-integer Shapiro steps in highly transmissive InSb nanoflag Josephson junctions

We investigate a ballistic InSb nanoflag-based Josephson junction with Nb superconducting contacts. The high transparency of the superconductor-semiconductor interfaces enables the exploration of quantum transport with parallel short and long conducting channels. Under microwave irradiation, we observe half-integer Shapiro steps that are robust to temperature, suggesting their possible non-equilibrium origin. Our results demonstrate the potential of ballistic InSb nanoflags Josephson junctions as a valuable platform for understanding the physics of hybrid devices and investigating their non-equilibrium dynamics.Comment: 37 pages, 14 figure

Examining the Relationship of Clinical and Laboratory Parameters With Infectiousness to Phlebotomus perniciosus and Its Potential Infectivity in Dogs With Overt Clinical Leishmaniasis

Infected dogs are considered the main domestic animal reservoirs for Leishmania infantum parasite. Infectiousness to competent phlebotomine vectors has been associated with many factors, the main being the severity of the disease exhibited by infected dogs. This study examines the relationship between different clinical parameters and the infectiousness to colonized Phlebotomus perniciosus sand flies having a blood meal on dogs. Data obtained in the present study come from an untreated group of Leishmania sick dogs submitted to xenodiagnosis for the evaluation of a spot on insecticide solution. Seventeen dogs were diagnosed as affected by leishmaniasis through clinical examination, immunofluorescence antibody test (IFAT) serology, and loop-mediated isothermal amplification (LAMP). The disease severity (clinical score) was staged by using a numeric value derived from eight clinical and parasitological parameters. Xenodiagnosis was performed on caged dogs exposed for 1.5 h to sand-fly bites. The following parameters related to sand flies were examined: blood feeding (% of blood engorged females), promastigote detection (% of promastigote-positive sand flies), promastigote burden, and the promastigote stage maturation (potential transmissibility rate). Statistical relationship between the clinical score and entomological parameters was investigated, as well as the possible correlation between each clinical and laboratory parameters and sand fly infection/infectivity. The severity of clinical score may influence the blood feeding by, and the probability of promastigote detection in, sand flies; skin lesions seem to be the main factor that influences the rate of blood feeding. Promastigote burden is related to IFAT titer, skin lesions, and clinical score. All entomological parameters are strongly related among them. This study confirms that both P. perniciosus infection and infectivity are influenced by a dog’s clinical condition

SARS-CoV-2 multi-variant rapid detector based on graphene transistor functionalized with an engineered dimeric ACE2 receptor

Reliable point-of-care (POC) rapid tests are crucial to detect infection and contain the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The emergence of several variants of concern (VOC) can reduce binding affinity to diagnostic antibodies, limiting the efficacy of the currently adopted tests, while showing unaltered or increased affinity for the host receptor, angiotensin converting enzyme 2 (ACE2). We present a graphene field-effect transistor (gFET) biosensor design, which exploits the Spike-ACE2 interaction, the crucial step for SARS-CoV-2 infection. Extensive computational analyses show that a chimeric ACE2-Fragment crystallizable (ACE2-Fc) construct mimics the native receptor dimeric conformation. ACE2-Fc functionalized gFET allows in vitro detection of the trimeric Spike protein, outperforming functionalization with a diagnostic antibody or with the soluble ACE2 portion, resulting in a sensitivity of 20 pg/mL. Our miniaturized POC biosensor successfully detects B.1.610 (pre-VOC), Alpha, Beta, Gamma, Delta, Omicron (i.e., BA.1, BA.2, BA.4, BA.5, BA.2.75 and BQ.1) variants in isolated viruses and patient's clinical nasopharyngeal swabs. The biosensor reached a Limit Of Detection (LOD) of 65 cps/mL in swab specimens of Omicron BA.5. Our approach paves the way for a new and reusable class of highly sensitive, rapid and variant-robust SARS-CoV-2 detection systems

A note on the initial-boundary value problem for continuity equations with rough coefficients

In this note we establish the existence of solutions of initial-boundary value problems for continuity equations with low regularity coefficients. We also announce a uniqueness result and some related counterexamples

Control-FREEC viewer: a tool for the visualization and exploration of copy number variation data

Abstract Background Copy number alterations (CNAs) are genetic changes commonly found in cancer that involve different regions of the genome and impact cancer progression by affecting gene expression and genomic stability. Computational techniques can analyze copy number data obtained from high-throughput sequencing platforms, and various tools visualize and analyze CNAs in cancer genomes, providing insights into genetic mechanisms driving cancer development and progression. However, tools for visualizing copy number data in cancer research have some limitations. In fact, they can be complex to use and require expertise in bioinformatics or computational biology. While copy number data analysis and visualization provide insights into cancer biology, interpreting results can be challenging, and there may be multiple explanations for observed patterns of copy number alterations. Results We created Control-FREEC Viewer, a tool that facilitates effective visualization and exploration of copy number data. With Control-FREEC Viewer, experimental data can be easily loaded by the user. After choosing the reference genome, copy number data are displayed in whole genome or single chromosome view. Gain or loss on a specific gene can be found and visualized on each chromosome. Analysis parameters for subsequent sessions can be stored and images can be exported in raster and vector formats. Conclusions Control-FREEC Viewer enables users to import and visualize data analyzed by the Control-FREEC tool, as well as by other tools sharing a similar tabular output, providing a comprehensive and intuitive graphical user interface for data visualization