110 research outputs found

    Legal Decisions, Affective Justice, and ‘Moving On?’

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    Our paper argues that a move away from the linear approach adopted in transitional justice scholarship is required to the question of ‘moving on’, understood as the way in which a post-dictatorial or a post-conflict regime addresses the past injustices of the predecessor regime. We consider this question in relation to two case studies: post-dictatorial Albania and post-conflict Sierra Leone. Both examples point to important factors that underpin the meanings of ‘moving on’ and of justice, when analysed through a law and aesthetics lens. It has long been established that legal scholarship that makes use of works of art aids and clarifies the points that it wants to make. We examine the power of certain art forms, namely the way in which space ‘speaks’ and the narratives found in an image in the Albanian context, and the use of film to provide a deeper appreciation of the conflict in the Sierra Leonean context. Different aesthetic practices have been used as a way to respond to historical injustice and mass atrocity, also when partial justice (through the law) has been achieved. Our article argues that law’s limitations can be understood through the process of unravelling the pieces of the puzzle that make up affective justice. Artistic representation allows for a more complex narration than law’s linear demands

    The Pediatric Obsessive-Compulsive Disorder Treatment Study II: rationale, design and methods

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    This paper presents the rationale, design, and methods of the Pediatric Obsessive-Compulsive Disorder Treatment Study II (POTS II), which investigates two different cognitive-behavior therapy (CBT) augmentation approaches in children and adolescents who have experienced a partial response to pharmacotherapy with a serotonin reuptake inhibitor for OCD. The two CBT approaches test a "single doctor" versus "dual doctor" model of service delivery. A specific goal was to develop and test an easily disseminated protocol whereby child psychiatrists would provide instructions in core CBT procedures recommended for pediatric OCD (e.g., hierarchy development, in vivo exposure homework) during routine medical management of OCD (I-CBT). The conventional "dual doctor" CBT protocol consists of 14 visits over 12 weeks involving: (1) psychoeducation, (2), cognitive training, (3) mapping OCD, and (4) exposure with response prevention (EX/RP). I-CBT is a 7-session version of CBT that does not include imaginal exposure or therapist-assisted EX/RP. In this study, we compared 12 weeks of medication management (MM) provided by a study psychiatrist (MM only) with two types of CBT augmentation: (1) the dual doctor model (MM+CBT); and (2) the single doctor model (MM+I-CBT). The design balanced elements of an efficacy study (e.g., random assignment, independent ratings) with effectiveness research aims (e.g., differences in specific SRI medications, dosages, treatment providers). The study is wrapping up recruitment of 140 youth ages 7–17 with a primary diagnosis of OCD. Independent evaluators (IEs) rated participants at weeks 0,4,8, and 12 during acute treatment and at 3,6, and 12 month follow-up visits

    Evidence-Based Assessment of Child Obsessive Compulsive Disorder: Recommendations for Clinical Practice and Treatment Research

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    Obsessive-compulsive disorder (OCD) presents heterogeneously and can be difficult to assess in youth. This review focuses on research-supported assessment approaches for OCD in childhood. Content areas include pre-visit screening, diagnostic establishment, differential diagnosis, assessment of comorbid psychiatric conditions, tracking symptom severity, determining psychosocial functioning, and evaluating clinical improvement. Throughout this review, similarities and differences between assessment approaches geared towards clinical and research settings are discussed

    A systematic review of mental health outcome measures for young people aged 12 to 25 years

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    Bayesian supervised machine learning classification of neural networks with pathological perturbations

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    Objective. Extraction of temporal features of neuronal activity from electrophysiological data can be used for accurate classification of neural networks in healthy and pathologically perturbed conditions. In this study, we provide an extensive approach for the classification of human in vitro neural networks with and without an underlying pathology, from electrophysiological recordings obtained using a microelectrode array (MEA) platform. Approach. We developed a Dirichlet mixture (DM) Point Process statistical model able to extract temporal features related to neurons. We then applied a machine learning algorithm to discriminate between healthy control and pathologically perturbed in vitro neural networks. Main Results. We found a high degree of separability between the classes using DM point process features (p-value <0.001 for all the features, paired t-test), which reaches 93.10 of accuracy (92.37 of ROC AUC) with the Random Forest classifier. In particular, results show a higher latency in firing for pathologically perturbed neurons (43 ± 16 ms versus 67 ± 31 ms, μIG feature distribution). Significance. Our approach has been successful in extracting temporal features related to the neurons' behaviour, as well as distinguishing healthy from pathologically perturbed networks, including classification of responses to a transient induced perturbation
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