1,056 research outputs found

    Human Resource Practices as Predictors of Work-Family Outcomes and Employee Turnover

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    Drawing on a non-random sample of 557 dual- earner white collar employees, this paper explores the relationship between human resource practices and three outcomes of interest to firms and employees: work-family conflict, employees’ control over managing work and family demands, and employees’ turnover intentions. We analyze three types of human resource practices: work-family policies, HR incentives designed to induce attachment to the firm, and the design of work. In a series of hierarchical regression equations, we find that work design characteristics explain the most variance in employees’ control over managing work and family demands, while HR incentives explain the most variance in work-family conflict and turnover intentions. We also find significant gender differences in each of the three models. Our results suggest that the most effective organizational responses to work-family conflict and to turnover are those that combine work-family policies with other human resource practices, including work redesign and commitment-enhancing incentives

    Academic Leaders Shaping Work-Life Culture

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    Presenters and participants will discuss emerging strategies and best practices available to chairs to support the creation of departmental cultures that are friendly and responsive to the work-life needs of faculty and staff

    Gender, Family and Career in the Era of Boundarylessness: Determinants and Effects of Intra- and Inter-organizational Mobility

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    Changes in patterns of long-term employment make understanding the determinants of different career forms increasingly important to careers research. At the same time, the rise of dual-earner families demands greater attention to the ways in which gender and family characteristics shape careers than has been paid by traditional research. This paper addresses these issues, examining the determinants and consequences of intra-organizational and inter-organizational mobility, using a sample of employees from dual-earner couples. We find significant gender differences in these different types of career mobility, and in the effect of family relations on different forms of mobility. Women experience more inter-organizational mobility, while men experience more intra-organizational mobility. Having more children positively influences men’s intra-organizational mobility, but increases interorganizational mobility for women. Marital instability increases intra-organizational mobility among women, but has no effect among men. Each form of mobility has distinctive effects on objective and subjective indicators of career success for both men and women. Moving between organizations tends to depress earnings, but has no effect on how successful people feel in their careers. Job changes within an organization increase earnings, but have a negative effect on perceived success

    HIV DNA Reservoir Increases Risk for Cognitive Disorders in cART-Nave Patients

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    Objectives Cognitive impairment remains frequent in HIV, despite combination antiretroviral therapy (cART). Leading theories implicate peripheral monocyte HIV DNA reservoirs as a mechanism for spread of the virus to the brain. These reservoirs remain present despite cART. The objective of this study was to determine if the level of HIV DNA in CD14+ enriched monocytes predicted cognitive impairment and brain injury. Methods We enrolled 61 cART-naĂŻve HIV-infected Thais in a prospective study and measured HIV DNA in CD14+ enriched monocyte samples in a blinded fashion. We determined HAND diagnoses by consensus panel and all participants underwent magnetic resonance spectroscopy (MRS) to measure markers of brain injury. Immune activation was measured via cytokines in cerebrospinal fluid (CSF). Results The mean (SD) age was 35 (6.9) years, CD4 T-lymphocyte count was 236 (139) and log10 plasma HIV RNA was 4.8 (0.73). Twenty-eight of 61 met HAND criteria. The log10 CD14+ HIV DNA was associated with HAND in unadjusted and adjusted models (p = 0.001). There was a 14.5 increased odds ratio for HAND per 1 log-value of HIV DNA (10-fold increase in copy number). Plasma CD14+ HIV DNA was associated with plasma and CSF neopterin (p = 0.023) and with MRS markers of neuronal injury (lower N-acetyl aspartate) and glial dysfunction (higher myoinositol) in multiple brain regions. Interpretation Reservoir burden of HIV DNA in monocyte-enriched (CD14+) peripheral blood cells increases risk for HAND in treatment-naĂŻve HIV+ subjects and is directly associated with CSF immune activation and both brain injury and glial dysfunction by MRS

    Associations between Indicators of Livestock Farming Intensity and Incidence of Human Shiga Toxin-Producing Escherichia Coli Infection

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    The impact of livestock farming on the incidence of human Shiga toxin-producing Escherichia coli (STEC) infection was assessed by using several livestock density indicators (LDI) that were generated in a systematic approach. A total of 80 LDI were considered suitable proxy measures for livestock density. Multivariate Poisson regression identified several LDI as having a significant spatial association with the incidence of human STEC infection. The strongest associations with human STEC infection were the ratio of beef cattle number to human population and the application of manure to the surface of agricultural land by a solid spreader and by a liquid spreader showed. This study demonstrates the value of using a systematic approach in identifying LDI and other spatial predictors of disease

    Web Experience and Growth

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    Measuring the impact of user experience on growth and return on investment is essential in making a business case for developing or redesigning websites in a company. Thus, examining factors that can impact the return on investment of web design are of great importance to companies. In this paper, we develop a basic model to provide a scientific framework for predicting the business value of web design. We test our model via an experiment using an actual live website in a Fortune 500 company

    A comparison of the Greek ACE-III, M-ACE, ACE-R, MMSE and ECAS in the assessment and identification of Alzheimer’s Disease

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    International audienceIntroduction: The present study attempted to adapt into Greek and validate the Addenbrooke's Cognitive Examination-III (ACE-III) and Mini-ACE (M-ACE) against their predecessors Addenbrooke's Cognitive Examination-Revised (ACE-R) and Mini-Mental State Examination (MMSE) in an Alzheimer's disease (AD) population. Notably, the present study also aimed to appraise the utility of each screen by conducting a comparison of the psychometric properties of ACE-III, MACE , ACE-R, MMSE, and Edinburgh Cognitive and Behavioural ALS Screen (ECAS) in detecting AD. Methods: Forty AD patients were recruited and matched with 38 controls. Bayes correlation analysis was conducted to examine convergent validity. Receiver operating characteristics curve analysis was implemented to appraise the sensitivity and specificity of the tests. Results: The ACE-III, MACE and ECAS and its sub-scores robustly correlated with ACE-R and MMSE. The ACE-III and the ECAS-ALS Non-Specific score were the most sensitive and specific tools in detecting AD, closely followed by ECAS Total score and MACE. Solely ECAS Total score correlated with the duration of disease. Discussion: ACE-III and MACE are validated and showed very good psychometric properties in detecting AD and may be considered in hectic clinical settings. ECAS total score and ECAS-ALS Non-Specific showed comparable psychometric properties and may be considered in poly-pathological clinics for the detection and monitoring of AD in patients with motor impairments common to neurodegenerative diseases
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