51 research outputs found

    Evolutionary perspectives in computer music

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    This paper presents a brief overview of music evolution - western and non-western music - from its genesis to serialism and the Darmstadt school. Some mathematical aspects of music are then presented and confronted with music as a form of art. Some questions follow: are these two (very) distinct aspects compatible? Can computers be of real help in automatic composition? Evolutionaty Algorithms (EAs) - Genetic Algorithms (GAs), Genetic Programming (GP), Particle Swarm Optimization (PSO) and Ant Colony Optimization (ACO) - are then introduced and some results of GAs and GPs application to music generation are analysed. Variable fitness functions and PSO application seems a promising way to explore. However, what output should be envisaged? Should we expect that computer music sounds as human music, or should we look for a totally different way to explore and listen? How far can go computer creativity and in what direction?N/

    Computational intelligence techniques in engineering

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    This article shows how CI techniques overpass the strict limits of Artificial Intelligence (AI) field and can help solving real problems from distinct engineering areas: Mechanical, Computer Science and Electrical Engineering. An introduction to each of the CI main areas is made and three systems are briefly described. The results are, in each case, very promisingN/

    Dietary protein, growth, nutrient utilization and body composition of juvenile blackspot seabream, Pagellus bogaraveo (Brunnich)

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    When considering new marine species for Mediterranean aquaculture, blackspot seabream emerges as a potential candidate. However, there are scarce data on the nutritional requirements and optimal growth conditions of this species. A 12-week feeding trial was conducted to evaluate the effects of dietary protein on growth, nutrient utilization and body composition of blackspot seabream (23 g). Five isolipidic diets (12%) with graded levels of protein (20-60%) were distributed, twice a day, to duplicate groups of fish, until satiation. Growth increased significantly with increasing dietary protein up to 40%, but higher protein levels induced a similar daily growth index (1.4). Feed conversion ratio (FCR) decreased with increasing levels of dietary protein (4.2-1.6). No significant differences were detected in protein of whole body blackspot seabream among treatments, but fat percentage decreased with increasing dietary protein. Dry matter and energy digestibility showed a concomitant increase with the reduction in dietary wheat meal, attaining maximal values with high protein diets. These results suggested that the most favourable values for growth and FCR are obtained with diets containing 40% protein. However, the excessive lipid deposition reveals that more nutritional studies are necessary before the species can be established in aquaculture

    A INTRÍNSECA RELAÇÃO ENTRE O ESTADO CAPITALISTA E AS POLÍTICAS SOCIAIS

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    The objective of this article is to analyze the characteristics of the Capitalist State, considering the forms of organization that it has assumed in the historical scenario, from the eighteenth century, as well as its relation with social policies. We use studies that analyze the Capitalist State and Social Policies. It is evident that social policies are the result of the conflicts of social forces, where class struggle and the relation of domination of one class over another must be mediated by the State. In this way, the guarantee of a minimum is necessary, as it allows the worker to remain active in the productive process, through the sale of his work force. It should be noted that the study is part of the Master's thesis developed in the Stricto Sensu Postgraduate Program in Education Master's Degree / PPGE, at UNIOESTE / Cascavel, whose objective consisted in analyzing the pedagogical principles referring to the student training contained in the legislation to High School and vocational secondary technical education, after the LDB 9394/96.O objetivo do artigo consiste em analisar as características do Estado Capitalista, considerando as formas de organização que este foi assumindo no cenário histórico, a partir do século XVIII, assim como sua relação com as políticas sociais. Utilizamos de estudos que analisam o Estado Capitalista e as Políticas Sociais. Evidencia-se que as políticas sociais são resultantes dos embates das forças sociais, onde a luta de classes e a relação de dominação de uma classe sobre a outra precisa ser mediada pelo Estado. Desta forma, a garantia de um mínimo, faz-se necessária, à medida que possibilita o trabalhador manter-se ativo no processo produtivo, por meio da venda de sua força de trabalho. Salienta-se que o estudo faz parte da dissertação de Mestrado desenvolvida no Programa de Pós-Graduação Stricto Sensu em Educação Nível de Mestrado/PPGE, na UNIOESTE/Cascavel, cujo objetivo consistiu na análise dos princípios pedagógicos referentes à formação discente contidos na legislação voltada aoensino médio e à educação profissional técnica de nível  médio, após a LDB 9394/96

    Tiburones de profundidad en las capturas accesorias de una campaña de pesca experimental de pez sable negro (Aphanopus spp.) en las islas Canarias (Atlántico nororiental)

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    The deep-sea sharks associated as by-catch of the Madeiran midwater drifting longline fishery for scabbardfishes (Aphanopus spp.) were investigated by means of an experimental survey at 800-1200 m depth within the Canary Islands Exclusive Economic Zone, whose fishing grounds have been exploited during the past 15 years. Nine species of chondrichthyans were identified, belonging to five families: Pseudotriakidae, Centrophoridae, Etmopteridae, Somniosidae and Chimaeridae. Data on length, weight and sex ratio for the 436 chondrichthyan individuals caught in the March 2009 survey are given. Several voucher specimens of each species caught were deposited in the collections of the Natural History Museum of Funchal.Se investigaron los tiburones de profundidad en las capturas accesorias de la pesquería de palangre de deriva de media agua que tiene por objetivo el sable negro (Aphanopus spp.) mediante una campaña experimental en la Zona Económica Exclusiva de Canarias a profundidades de 800 a 1200 m, en caladeros que han venido siendo explotados en los últimos 15 años. Se identificaron nueve especies de condrictios pertenecientes a cinco familias: Pseudotriakidae, Centrophoridae, Etmopteridae, Somniosidae y Chimaeridae. Se aportan datos de talla, peso y proporción de sexos para los 436 ejemplares de condrictios capturados en la campaña de marzo de 2009. Los especímenes de referencia capturados fueron depositados en las colecciones del Museo de Historia Natural de Funchal

    A Review on Humanized Computational Intelligence

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    Computational Intelligence (CI) has three main foundations: Neural Networks, Evolutionary Computation (EC) and Fuzzy Systems (FS). Collaborating systems based on these models have been built and installed in prototypes and successful consumer products. However, creativity still is a main human task, in great part due to the presence of subjective values and psychological / emotional responses in the evaluation of the created objects. In this context the Interactive Evolutionary Computation (IEC), a paradigm in which humans directly intervene in fitness evaluation, is a new direction for CI research. Art, education and engineering are some examples of IEC application domains.N/

    Endemic Burkitt lymphoma avatar mouse models for exploring inter-patient tumor variation and testing targeted therapies

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    Endemic Burkitt lymphoma (BL) is a childhood cancer in sub-Saharan Africa characterized by Epstein-Barr virus and malaria-associated aberrant B-cell activation and MYC chromosomal translocation. Survival rates hover at 50% after conventional chemotherapies; therefore, clinically relevant models are necessary to test additional therapies. Hence, we established five patient-derived BL tumor cell lines and corresponding NSG-BL avatar mouse models. Transcriptomics confirmed that our BL lines maintained fidelity from patient tumors to NSG-BL tumors. However, we found significant variation in tumor growth and survival among NSG-BL avatars and in Epstein-Barr virus protein expression patterns. We tested rituximab responsiveness and found one NSG-BL model exhibiting direct sensitivity, characterized by apoptotic gene expression counterbalanced by unfolded protein response and mTOR pro-survival pathways. In rituximab-unresponsive tumors, we observed an IFN-α signature confirmed by the expression of IRF7 and ISG15. Our results demonstrate significant inter-patient tumor variation and heterogeneity, and that contemporary patient-derived BL cell lines and NSG-BL avatars are feasible tools to guide new therapeutic strategies and improve outcomes for these children
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