922 research outputs found

    The 5 C\u27s: A Problem-Solving Approach to Study Skills

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    The most expansive and mobilizing impression a student can acquire is that what is, may be, but it can be otherwise. The attitude that all life and circumstances are amenable to analysis and some measure of modification is the avowed purpose of the strategy to improve Study Skills described below

    The Preparation of Teacher Candidates for K-12 Online Learning Environments: A Case Study

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    The purpose of this study was to determine how teacher education programs may better prepare teacher candidates to teach in K-12 online learning environments. The primary research question addressed was: What specific knowledge, skills, and dispositions should teacher education programs include in their curriculum to better prepare teacher candidates to teach in K-12 online learning environments? To answer this question, the researcher employed a qualitative case study methodological approach in which the study’s participant was observed for three months as he taught multiple sixth grade mathematics classes in a fully online learning environment. Findings from this study indicate that teacher education programs should offer field experiences in K-12 online learning environments and that teacher educators must learn, develop, and model the necessary knowledge, skills, and dispositions relevant to K-12 online learning environments

    Immunomodulators for Asthma

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    New information regarding the molecular mechanisms of allergic disorders has led to a variety of novel therapeutic approaches. This article briefly reviews the pathogenesis of asthma and allergic diseases, discusses the rationale behind using immunomodulators in these diseases; and examines the therapeutic effects of immunomodulators on allergic diseases. There are a number of immunomodulators that have been developed for the treatment of allergic disorders. Some have looked very promising in pre-clinical trials, but have not shown significant benefits in human clinical trials thus indicating the disparity between mouse models and human asthma. This review focuses on immunomodulators that are in human clinical trials and not molecules in pre-clinical development

    Obstructive Sleep Apnea Syndrome: From Phenotype to Genetic Basis

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    Obstructive sleep apnea syndrome (OSAS) is a complex chronic clinical syndrome, characterized by snoring, periodic apnea, hypoxemia during sleep, and daytime hypersomnolence. It affects 4-5% of the general population. Racial studies and chromosomal mapping, familial studies and twin studies have provided evidence for the possible link between the OSAS and genetic factors and also most of the risk factors involved in the pathogenesis of OSAS are largely genetically determined. A percentage of 35-40% of its variance can be attributed to genetic factors. It is likely that genetic factors associated with craniofacial structure, body fat distribution and neural control of the upper airway muscles interact to produce the OSAS phenotype. Although the role of specific genes that influence the development of OSAS has not yet been identified, current researches, especially in animal model, suggest that several genetic systems may be important. In this chapter, we will first define the OSAS phenotype, the pathogenesis and the risk factors involved in the OSAS that may be inherited, then, we will review the current progress in the genetics of OSAS and suggest a few future perspectives in the development of therapeutic agents for this complex disease entity

    Aerosol Single Scattering Albedo retrieval in the UV range: an application to OMI satellite validation

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    Abstract. The aerosol Single Scattering Albedo (SSA) and Absorbing Aerosol Optical Depth (AAOD) at 320.1 nm are derived at Rome site by the comparison between Brewer and modelled spectra. The UVSPEC radiative transfer model is used to calculate the UV irradiances for different SSA values, taking into account as input data total ozone and Aerosol Optical Depth (AOD) obtained from Brewer spectral measurements. The accuracy in determining SSA depends on the aerosol amount and on Solar Zenith Angle (SZA) value: SSA uncertainty increases when AOD and SZA decrease. The monthly mean values of SSA and AAOD during the period January 2005–June 2008 are analysed, showing a monthly and seasonal variability. It is found that the SSA and AAOD averages are 0.80±0.08 and 0.056±0.028, respectively. AAOD retrievals are also used to quantify the error in the Ozone Monitoring Instrument (OMI) surface UV products due to absorbing aerosols, not included in the current OMI UV algorithm. OMI and Brewer UV irradiances at 324.1 nm and Erythemal Dose Rates (EDRs) under clear sky conditions, are compared as a function of AAOD. Three methods are considered to investigate on the applicability of an absorbing aerosol correction on OMI UV data at Rome site. Depending on the correction methodology, the bias value decreases from 18% to 2% for spectral irradiance at 324.1 nm and from 25% to 8% for EDR

    Semiempirical formula for two-nucleon emission induced by short-range correlations in electron and neutrino scattering

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    A semiempirical formula is proposed for the emission cross section of two correlated nucleons. We assume that the two-particle emission response is proportional to the two-particle two-hole phase space multiplied by an averaged single-nucleon response. The effect of the short-range correlations is encoded in a correlation coefficient that is linked to an average of the high-momentum distribution of a nucleon pair. The correlation coefficient depends only on the momentum transfer and is obtained from a fit to the tail of the phenomenological scaling function. We present predictions for the inclusive two-nucleon emission cross section induced by electrons and neutrinos including short-range correlations and meson-exchange currents.Comment: 14 pages, 8 figures. Major revision, with 5 more pages, a new section, an appendix and a figur

    Fast UPLC/PDA determination of squalene in Sicilian P.D.O. pistachio from Bronte: optimization of oil extraction method and analytical characterization

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    A fast reversed-phase UPLC method was developed for squalene determination in Sicilian pistachio samples that entry in the European register of the products with P.D.O. In the present study the SPE procedure was optimized for the squalene extraction prior to the UPLC/PDA analysis. The precision of the full analytical procedure was satisfactory and the mean recoveries were 92.8 + 0.3 % and 96.6 + 0.1 % for 25 and 50 mg L-1 level of addition, respectively. Selected chromatographic conditions allowed a very fast squalene determination; in fact it was well separated in ~ 0.54 min with good resolution. Squalene was detected in all the pistachio samples analyzed and the levels ranged from 55.45 to 226.34 mg . kg-1. Comparing our results with those of other studies it emerges that squalene contents in P.D.O. Sicilian pistachio samples, generally, were higher than those measured for other samples of different geographic origins
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