2,780 research outputs found

    Study of Scintillator Strip with Wavelength Shifting Fiber and Silicon Photomultiplier

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    The performance of the 200×2.5×1200\times2.5\times1 cm3^3 plastic scintillator strip with wavelength shifting fiber read-out by two novel photodetectors called Silicon PhotoMultipliers (SiPMs) is discussed. The advantages of SiPM relative to the traditional multichannel photomultiplier are shown. Light yield and light attenuation measurements are presented. This technique can be used in muon or calorimeter systems.Comment: 9 pages, 5 figure

    Loss of Wwox Perturbs Neuronal Migration and Impairs Early Cortical Development

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    Mutations in the WWOX gene cause a broad range of ultra-rare neurodevelopmental and brain degenerative disorders, associated with a high likelihood of premature death in animal models as well as in humans. The encoded Wwox protein is a WW domain-containing oxidoreductase that participates in crucial biological processes including tumor suppression, cell growth/differentiation and regulation of steroid metabolism, while its role in neural development is less understood. We analyzed the exomes of a family affected with multiple pre- and postnatal anomalies, including cerebellar vermis hypoplasia, severe neurodevelopmental impairment and refractory epilepsy, and identified a segregating homozygous WWOX mutation leading to a premature stop codon. Abnormal cerebral cortex development due to a defective architecture of granular and molecular cell layers was found in the developing brain of a WWOX-deficient human fetus from this family. A similar disorganization of cortical layers was identified in lde/lde rats (carrying a homozygous truncating mutation which disrupts the active Wwox C-terminal domain) investigated at perinatal stages. Transcriptomic analyses of Wwox-depleted human neural progenitor cells showed an impaired expression of a number of neuronal migration-related genes encoding for tubulins, kinesins and associated proteins. These findings indicate that loss of Wwox may affect different cytoskeleton components and alter prenatal cortical development, highlighting a regulatory role of the WWOX gene in migrating neurons across different species

    Search for the h_c meson in B^+- ->h_c K^+-

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    We report a search for the hch_c meson via the decay chain B±hcK±B^{\pm}\to h_c K^{\pm}, \etac \gamma with ηcKS0K±π\eta_c \to K_S^0 K^{\pm} \pi^{\mp} and ppˉp\bar{p}. No significant signals are observed. We obtain upper limits on the branching fractions for B±ηcγK±B^{\pm} \to \eta_c\gamma K^{\pm} in bins of the ηcγ\eta_c\gamma invariant mass. The results are based on an analysis of 253 fb1^{-1} of data collected by the Belle detector at the KEKB e+ee^+e^- collider.Comment: 12 pages, 6 figures, submitted to Phys. Rev.

    Study of the decays B->D_s1(2536)+ anti-D(*)

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    We report a study of the decays B -> D_s1(2536)+ anti-D(*), where anti-D(*) is anti-D0, D- or D*-, using a sample of 657 x 10^6 B anti-B pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e+e- collider. The branching fractions of the decays B+ -> D_s1(2536)+ anti-D0, B0 -> D_s1(2536)+ D- and B0 -> D_s1(2536)+ D*- multiplied by that of D_s1(2536)+ -> (D*0K+ + D*+K0) are found to be (3.97+-0.85+-0.56) x 10^-4, (2.75+-0.62+-0.36) x 10^-4 and (5.01+-1.21+-0.70) x 10^-4, respectively.Comment: 6 pages, 2 figues, submitted to PRD (RC

    Performance of the first prototype of the CALICE scintillator strip electromagnetic calorimeter

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    A first prototype of a scintillator strip-based electromagnetic calorimeter was built, consisting of 26 layers of tungsten absorber plates interleaved with planes of 45x10x3 mm3 plastic scintillator strips. Data were collected using a positron test beam at DESY with momenta between 1 and 6 GeV/c. The prototype's performance is presented in terms of the linearity and resolution of the energy measurement. These results represent an important milestone in the development of highly granular calorimeters using scintillator strip technology. This technology is being developed for a future linear collider experiment, aiming at the precise measurement of jet energies using particle flow techniques

    Evidence for B to K eta' gamma Decays at Belle

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    We present the results of a search for the radiative decay (B -> K eta' gamma) and find evidence for (B^+ -> K^+ eta' gamma) decays at the 3.3 standard deviation level with a partial branching fraction of (3.6 +/- 1.2 +/- 0.4) x 10e-6, where the first error is statistical and the second systematic. This measurement is restricted to the region of combined (K eta') invariant mass less than 3.4GeVc^2. A 90% confidence level upper limit of 6.4 x 10e-6 is obtained for the decay (B^0 -> K^0 eta' gamma) in the same (K eta') invariant mass region. These results are obtained from a 605 fb^-1 data sample containing 657 x 10e6 B anti-B pairs collected at the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e^+e^- collider.Comment: 5 pages, 4 figures. Submitted to PRD-RC on 6/8/0
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