An X-ray photoelectron spectroscopic study of electrochemically deposited Fe-P thin films on copper substrate

Electrochemically deposited Fe-P magnetic thin film from acidic tartarate complex bath solution was characterized by X-ray photoelectron spectroscopy. As-prepared film contains both Fe3+- and P5+ -like species, whereas the same film after 10 and 20 min sputtering shows peaks corresponding to Fe metal as well as P(δ-) species along with P5+ species. The film after heat-treatment contains Fe3+ together with P5+ and Pδ- species, whereas heat-treated film after sputtering shows the presence of both Fe metal and Fe2+ species. There is an increase in Pδ- intensity on sputtering the heat-treated film. © 2002 Elsevier Science B.V. All rights reserved

Pattern and pharmacotherapy of acute poisonings presenting to a tertiary care centre

Background: Acute poisoning, a therapeutic emergency and one of the common causes of morbidity and mortality globally. The rate of mortality in developed countries range from 1-2%, but in India it varies between 15-30%. According to World Health Organization (WHO), globally more than three million acute poisoning cases with 2,20,000 deaths occur annually. Most of the fatalities are due to the victim not reaching the hospital in time. This study aims to evaluate the pattern of acute cases of poisoning in tertiary care hospital attached to BMCRI.Methods: Prospective, observational study based on hospital records at tertiary care hospital (twelve months). Data regarding demographic profile and treatment was collected. Data was analyzed using descriptive statistics and SPSS-24.Results: Out of a total of 810 poisoning cases, 608 were included (381 poisoning, 138 drug overdose and 89 snake bite). Organophosphorus compounds (OPC) (131/608) and Aluminium phosphide (43/608) were the commonest poisons consumed in the age group 21-30 years. Sedative-hypnotics, non-benzodiazepine antiepileptics (non BZD AEDs) and paracetamol were common drug overdose cases. Snake bite accounted for 14.6%.Conclusions: OP compounds were the most common among poisons, while sedatives-hypnotics were frequently consumed drugs, followed by Snake bite. Young adults from urban areas were the common victims with suicidal intention. This reflects the need for stringent rules regarding the availability and sale of drugs and poisonous substances

Cost optimization of cantilever retaining wall

This thesis presents a lucid model to obtain the optimum cost of a cantilever retaining wall having different cases of backfill (straight and inclined) and surcharge. A code written in Java, finds out all the sections of the cantilever retaining wall possible according to stability criteria that applies to all retaining walls and gives the optimum cost of a retaining wall of a given height and the required material properties to be used, while following the provisions of the Indian Standard Code, IS 456:2000for the sections. The freedom given for the person who uses the program to specify material properties and their costs add to the versatility of the code

Isolated, full-thickness proximal rectus femoris injury in competitive athletes: A systematic review of injury characteristics and return to play

BACKGROUND: Characteristics regarding mechanism of injury, management, and return-to-play (RTP) rate and timing are important when treating and counseling athletes with rectus femoris tears. PURPOSE: To systematically review the literature to better understand the prevalence, sporting activity, injury mechanisms, and treatment of patients with rectus femoris injury and to provide prognostic information regarding the rate and timing of RTP. STUDY DESIGN: Systematic review; Level of evidence, 4. METHODS: Following the 2020 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, we queried PubMed/MEDLINE, Cochrane, OVID, EMBASE, and Google Scholar in March 2022 for studies reporting on athletes sustaining isolated, full-thickness tearing, or bony avulsion injuries to the proximal rectus femoris during sporting activity. Excluded were studies without evidence of full-thickness tearing or avulsion, with athletes sustaining concomitant injuries, or with injuries occurring from nonsporting activities. The percentage of athletes sustaining injuries was calculated based on sport, injury mechanism, and management (nonoperative versus operative). RESULTS: Of 132 studies initially identified, 18 were included, comprising 132 athletes (mean age, 24.0 ± 5.4 years; range, 12-43 years). The most common sporting activities were soccer (70.5%) and rugby (15.2%). The most reported mechanisms of injury were kicking (47.6%) and excessive knee flexion/forced hip extension (42.9%). Avulsion injuries were reported in 86% (n = 114) of athletes. Nonoperative management was reported in 19.7% of athletes, with operative management performed in 80.3%. The mean follow-up time was 21.4 ± 11.4 months (range, 1.5-48 months). The RTP rate was 93.3% (n = 14) in nonoperatively treated and 100% (n = 106) in operatively treated athletes, and the mean RTP time was 11.7 weeks (range, 5.5-15.2 weeks) in nonoperatively treated and 22.1 weeks (range, 14.0-37.6 weeks) in operatively treated athletes. Complications were reported in 7.7% (2/26) of nonoperatively treated and 18% (n = 19/106) of operatively treated athletes. CONCLUSION: Full-thickness proximal rectus femoris injuries occurred most frequently in athletes participating in soccer and rugby secondary to explosive, eccentric contractions involved in kicking and sprinting. Operative management was performed in the majority of cases. Athletes who underwent operative repair had a 100% RTP rate versus 93.3% in athletes treated nonoperatively

Effects of benzamide on mitosis & chromosomes in mammalian cells in vitro

This article does not have an abstract

Parametric analysis of Asymmetric Spur Gear Tooth

Abstract Gear is a machine element used to transmit motion and power between rotating shafts by means of progressive engagement of projections called teeth. Gears are classified according to the relative position of the axes of the shaft, type of gearing, peripheral velocity of the gears and position of teeth on gear surface. Presently gears are suffered by backlash the amount by which the width of a tooth space exceeds the thickness of the engaging tooth on the pitch circles, undercut a condition in generated gear teeth when any part of the fillet curve lies inside of a line drawn tangent to the working profile at its lowest point and interference is an important aspect of kinematics of gearing. When the gear tooth tries to dig below the base circle of mating gear then the gear tooth action shall be non conjugate and violate the fundamental law of gearing this non conjugate action is called the interference . These defects can be eliminated by increasing the pressure angle, by increasing the addendum of mating gear and another way of increasing the load capacity of transmissions is to modify the involute geometry. This has been a standard practice in sophisticated gear design for many years. The nomenclature describing these types of gear modifications can be quite confusing with reference to addendum modification or profile shift. An additional alteration that is very rarely used is to make the gears asymmetric with different pressure angles for each side of the tooth. An asymmetric spur gear drive means that larger and smaller pressure angles are applied for the driving and coast sides. The two profiles of a gear tooth are functionally different for most gear drives. The workload on one side of profile is significantly higher than the other Gears. The main objective of this paper is to generate asymmetric spur gear tooth geometry for different pressure angles on drive and coast side using computer programme. Developed programme is used to create a finite element model of gear tooth to study the effect of bending stress at the critical section for different pressure angles, different number of teeth and module. To study the effect of above asymmetric spur tooth parameters Finite Element Analysis software ANSYS was used

Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus

Zika virus (ZIKV) is a re-emerging virus that has recently spread into dengue virus (DENV) endemic regions and cross-reactive antibodies (Abs) could potentially affect ZIKV pathogenesis. Using DENV-immune serum, it has been shown in vitro that antibody-dependent enhancement (ADE) of ZIKV infection can occur. Here we study the effects of pre-existing DENV immunity on ZIKV infection in vivo. We infect two cohorts of rhesus macaques with ZIKV; one cohort has been exposed to DENV 2.8 years earlier and a second control cohort is naïve to flaviviral infection. Our results, while confirming ADE in vitro, suggest that pre-existing DENV immunity does not result in more severe ZIKV disease. Rather our results show a reduction in the number of days of ZIKV viremia compared to naïve macaques and that the previous exposure to DENV may result in modulation of the immune response without resulting in enhancement of ZIKV pathogenesis

Tracking the polyclonal neutralizing antibody response to a dengue virus serotype 1 type-specific epitope across two populations in Asia and the Americas

The four dengue virus serotypes (DENV1-4) cause major public health problems worldwide. Highly neutralizing type-specific human monoclonal antibodies (hmAbs) target conformation-dependent epitopes on the DENV envelope protein, including 1F4, a DENV1 type-specific hmAb. Using a recombinant DENV2 virus displaying the DENV1 1F4 epitope (rDENV2/1), we measured the proportion and kinetics of DENV1 neutralizing antibodies targeting the 1F4 epitope in individuals living in Asia and the Americas where different DENV1 genotypes were circulating. Samples from 20 individuals were analyzed 3 and 18 months post-primary DENV1 infection, alongside samples from 4 individuals collected annually for four years post-primary DENV1 infection, from two studies in Nicaragua. We also analyzed convalescent post-primary DENV1 plasma samples from Sri Lankan individuals. We found that neutralizing antibodies recognizing the 1F4 epitope vary in prevalence across both populations and were detected from 20 days to four years post-infection. Additionally, both populations displayed substantial variability, with a range of high to low proportions of DENV1 type-specific neutralizing antibodies recognizing the 1F4 epitope seen across individuals. Thus, the 1F4 epitope is a major but not exclusive target of type-specific neutralizing antibodies post-primary infection with different DENV1 genotypes in Asia and Latin America, and additional epitopes likely contribute to type-specific neutralization of DENV1