111 research outputs found

    Promoting First Nations, Metis, and Inuit Youth Wellbeing through Culturally-Relevant Programming: The Role of Cultural Connectedness and Identity

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    Objectives: Although culturally relevant programming has been identified as a promising practice for promoting resiliency among First Nations, Métis, and Inuit (FNMI) youth, the specific ways in which these programs contribute to wellbeing are unclear. The Fourth R: Uniting Our Nations programs include an array of strengths-based culturally relevant programs for FNMI youth that have been found to increase wellbeing. The purpose of this study was to explore how culturally relevant programming provides a forum for intrapersonal and interpersonal growth. Methods: In-depth interviews were conducted with 12 adult FNMI community and education stakeholders who have had extensive involvement with the programs. Interviews were transcribed and analyzed with an inductive approach through the use of open-coding. Results: Two themes emerged to clarify the relationships between culturally relevant programming and youth wellbeing. The two interconnected themes were the importance of identity and belonging, and the role of cultural connectedness in promoting wellbeing among FNMI youth. Conclusion: Culturally relevant programming provides a powerful opportunity for youth to develop their personal sense of positive cultural identity and feelings of belonging. In addition, the sense of connection to culture was seen to have a direct positive impact on youth, partly through combatting shame

    Status of the Michigan Ultra‐Cold Spin‐Polarized Hydrogen Jet

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    Progress on the Michigan ultra‐cold proton‐spin‐polarized atomic‐hydrogen Jet target is presented. We describe the present status of the Jet and some beam test results. © 2004 American Institute of PhysicsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87591/2/639_1.pd

    Polarized Atomic Hydrogen Beam Tests in the Michigan Ultra‐Cold Jet Target

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    Progress on the Michigan ultra‐cold proton‐spin‐polarized atomic hydrogen Jet target is presented. We describe the present status of the Jet and some beam test results. © 2003 American Institute of PhysicsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87681/2/872_1.pd

    A supramolecular helix that disregards chirality

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    The functions of complex crystalline systems derived from supramolecular biological and non-biological assemblies typically emerge from homochiral programmed primary structures via first principles involving secondary, tertiary and quaternary structures. In contrast, heterochiral and racemic compounds yield disordered crystals, amorphous solids or liquids. Here, we report the self-assembly of perylene bisimide derivatives in a supramolecular helix that in turn self-organizes in columnar hexagonal crystalline domains regardless of the enantiomeric purity of the perylene bisimide. We show that both homochiral and racemic perylene bisimide compounds, including a mixture of 21 diastereomers that cannot be deracemized at the molecular level, self-organize to form single-handed helical assemblies with identical single-crystal-like order. We propose that this high crystalline order is generated via a cogwheel mechanism that disregards the chirality of the self-assembling building blocks. We anticipate that this mechanism will facilitate access to previously inaccessible complex crystalline systems from racemic and homochiral building blocks

    Cutaneous wound healing: recruiting developmental pathways for regeneration

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    Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy.

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    Purpose Indications for nipple-sparing mastectomy (NSM) have broadened to include the risk reducing setting and locally advanced tumors, which resulted in a dramatic increase in the use of NSM. The Oncoplastic Breast Consortium consensus conference on NSM and immediate reconstruction was held to address a variety of questions in clinical practice and research based on published evidence and expert panel opinion. Methods The panel consisted of 44 breast surgeons from 14 countries across four continents with a background in gynecology, general or reconstructive surgery and a practice dedicated to breast cancer, as well as a patient advocate. Panelists presented evidence summaries relating to each topic for debate during the in-person consensus conference. The iterative process in question development, voting, and wording of the recommendations followed the modified Delphi methodology. Results Consensus recommendations were reached in 35, majority recommendations in 24, and no recommendations in the remaining 12 questions. The panel acknowledged the need for standardization of various aspects of NSM and immediate reconstruction. It endorsed several oncological contraindications to the preservation of the skin and nipple. Furthermore, it recommended inclusion of patients in prospective registries and routine assessment of patient-reported outcomes. Considerable heterogeneity in breast reconstruction practice became obvious during the conference. Conclusions In case of conflicting or missing evidence to guide treatment, the consensus conference revealed substantial disagreement in expert panel opinion, which, among others, supports the need for a randomized trial to evaluate the safest and most efficacious reconstruction techniques

    Miocardiopatía por sepsis, reporte de un caso

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    La miocardiopatía inducida por sepsis es una causa de disfunción miocárdica reversible que se caracteriza por la afectación estructural y funcional del miocardio generada por las citocinas inflamatorias y disfunción mitocondrial. Se cree que aproximadamente hasta un 50% de los pacientes con sepsis grave y choque séptico padecen alguna forma de alteración sistólica de la función ventricular izquierda. Mujer de 37 años que presentó dolor abdominal con distensión abdominal y se presenta con choque séptico a la unidad de emergencia. Los exámenes de laboratorio demostraron un proceso infeccioso. Se realizó tomografía computarizada de abdomen que reveló colección pélvica en la fosa ilíaca derecha. El ecocardiograma transtorácico mostró hipocinesia generalizada del ventrículo izquierdo con fracción de eyección del ventrículo izquierdo reducida (25%). Se inició manejo con vasopresores e inotrópicos, antibioticoterapia, ventilación mecánica invasiva y reanimación hídrica guiada por metas, pero a pesar de todo el esfuerzo médico la paciente fallece
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