22 research outputs found

    A randomised controlled trial investigating the effect of nutritional supplementation on visual function in normal, and age-related macular disease affected eyes: design and methodology [ISRCTN78467674]

    Get PDF
    BACKGROUND: Age-related macular disease is the leading cause of blind registration in the developed world. One aetiological hypothesis involves oxidation, and the intrinsic vulnerability of the retina to damage via this process. This has prompted interest in the role of antioxidants, particularly the carotenoids lutein and zeaxanthin, in the prevention and treatment of this eye disease. METHODS: The aim of this randomised controlled trial is to determine the effect of a nutritional supplement containing lutein, vitamins A, C and E, zinc, and copper on measures of visual function in people with and without age-related macular disease. Outcome measures are distance and near visual acuity, contrast sensitivity, colour vision, macular visual field, glare recovery, and fundus photography. Randomisation is achieved via a random number generator, and masking achieved by third party coding of the active and placebo containers. Data collection will take place at nine and 18 months, and statistical analysis will employ Student's t test. DISCUSSION: A paucity of treatment modalities for age-related macular disease has prompted research into the development of prevention strategies. A positive effect on normals may be indicative of a role of nutritional supplementation in preventing or delaying onset of the condition. An observed benefit in the age-related macular disease group may indicate a potential role of supplementation in prevention of progression, or even a degree reversal of the visual effects caused by this condition

    Experimental evidence for sustained carbon sequestration in fire-managed, peat moorlands.

    Get PDF
    Peat moorlands are important habitats in the boreal region, where they store approximately 30% of the global soil carbon (C). Prescribed burning on peat is a very contentious management strategy, widely linked with loss of carbon. Here, we quantify the effects of prescribed burning for lightly managed boreal moorlands and show that the impacts on peat and C accumulation rates are not as bad as is widely thought. We used stratigraphical techniques within a unique replicated ecological experiment with known burn frequencies to quantify peat and C accumulation rates (0, 1, 3 and 6 managed burns since around 1923). Accumulation rates were typical of moorlands elsewhere, and were reduced significantly only in the 6-burn treatment. However, impacts intensified gradually with burn frequency; each additional burn reduced the accumulation rates by 4.9 g m−2 yr−1 (peat) and 1.9 g C cm−2 yr−1, but did not prevent accumulation. Species diversity and the abundance of peat-forming species also increased with burn frequency. Our data challenge widely held perceptions that a move to 0 burning is essential for peat growth, and show that appropriate prescribed burning can both mitigate wildfire risk in a warmer world and produce relatively fast peat growth and sustained C sequestration

    British Risorgimento II - Temperie politica e rappresentazioni simboliche

    No full text
    Il volume si pone a compimento del progetto PRIN 2008 British Risorgimento: rappresentazioni e interazioni britanniche nel processo di unificazione nazionale italiana, che ha coinvolto in un complesso itinerario d’indagine studiosi provenienti dalle Università di Bologna, Bari, Firenze, Roma La Sapienza e Parma. Come l’indice dei contributi mette in chiara evidenza, il progetto ha sviluppato molteplici direttrici di ricerca, sia nell’ambito privilegiato degli studi inglesi, sia in una più ampia prospettiva transnazionale e quindi pluridisciplinare, esplorando le modalità attraverso le quali il formarsi/decostruirsi di poetiche, di categorie e di identità, entra in relazione con le più ampie dinamiche di ordine culturale e politico che definiscono il quadro storico relativo all’arco temporale proposto, il periodo 1770- 1870
    corecore