Investigating the level of moral distress and its related factors among nurses in mazandaran burn center

Background and purpose: Moral distress is a common phenomenon in nursing professional and burn nurses are constantly faced with making different moral decisions for patients who are in terrible conditions. Therefore, nurses in burn units experience moral distress as mental tension. This study was conducted to determine the severity of moral distress and the factors associated with that in burn nurses. Materials and methods: A descriptive- analytical study was conducted using census sampling on 172 nurses working in Mazandaran burn center, 2014. Data was collected through identifying demographic and occupational characteristics of the nurses (using relevant questionnaires) and Corley’s Moral Distress Scale. Data analysis was performed applying Mann-Whitney and Kruskal-Wallis test. Results: The mean score for moral distress was 105.65±52.39 which indicates a moderate level experienced by nurses. Kruskal-Wallis test showed a significant positive correlation between educational level and level of moral distress (P=0.011). There was no significant association between moral distress and other individual and professional characteristics (P>0.05). Conclusion: Moral distress is accompanied by many complications that have direct effects on nurses’ professional practice. Therefore, nurse managers should consider this issue and plan for programs on appropriate coping strategies. © 2015, Mazandaran University of Medical Sciences. All rights reserved

Mapping a single-molecule folding process onto a topological space

Physics of protein folding has been dominated by conceptual frameworks including nucleation-propagation mechanism and the diffusion-collision model, none address topological properties of a chain during a folding process. Single-molecule interrogation of folded biomolecules has enabled real-time monitoring of the folding processes at an unprecedented resolution. Despite these advances, the topology landscape has not been fully mapped for any chain. Using a novel circuit topology approach, we map the topology landscape of a model polymeric chain. Inspired by single-molecule mechanical interrogation studies, we restrained the ends of a chain and followed fold nucleation dynamics. We find that, before the nucleation, transient local entropic loops dominate. Although the nucleation length of globules is dependent on the cohesive interaction, the ultimate topological states of the collapsed polymer are largely independent of the interaction but depend on the speed of the folding process. After the nucleation, transient topological rearrangements are observed that converge to a steady-state, where the fold grows in a self-similar manner

Electrical Burn Patients According to Electrical Voltage in Shahid Motahari Burn Center

Background: Electrical injuries are rarely happened but it makes more harmful lesions comparing to other thermal injuries. The aim of this study was to report electrical burned patients according to electrical voltage in Shahid Motahari Burn Center.Methods: This Routine data base study was performed on patients with electrical burns which were admitted to Shahid Motahari Burn Center from April 2010 to March 2012. Demographic and clinical data had gathered from medical records. Association between voltage and morbidity or mortality was evaluated used SPSS v. 16.Results: Mean total body surface area of 287 patients (283 (98.60%) male and 4 (1.4%) female) with mean age of 30±0.7 years was 13.56±0.76% (range 1-100). There were 203 patients (70.7%) with low and 84 patients (29.31%) with high voltage injury. There was significant association between voltage and place of injury (p=0.001).Conclusion: High voltage injuries constitute large number of electrical injuries which more of these injuries occurred outdoor and in workplace and need more hospitalization. High voltage injuries are related with more amputation, so people and authorities should pay more attention to such injuries

Shakedown analysis of the truss and comparing with the fundamental theoroms of alastic-plastic analysis implemented in a home-pakege and ANSYS

Research results in shakedown analysis of space steel structures are presented in this paper. The theory of shakedown and conventional methods of analysis are discussed, and the example of a shakedown of a truss-column is provided to illustrate the concepts of the nonlinear analysis and shakedown for space trusses [1; 4]

Difficulties for detecting the singular points with commercial programs in space structure and a method for determining the real capacity of the structures

For design purposes, the stability of any structure being designed is of paramount importance. The fact that it is possible to perform an analysis on a space structure which shows that the stresses in that structure are all below those permissible for the materials used in its construction, is in itself no guarantee that when the structure is loaded it will not collapse. In order to determine this, it is necessary to find out if the structure is stable under the action of the applied loads. The secondary paths, especially in unstable buckling can play the most important role in collapse of the structure [2]. Analytical solutions for space trusses of the desired type which cover both nonlinear deformation and stability are difficult to find in the literature. In order to provide the desired benchmark, the complete theory and the exacl soulution for the nonlinear deformation and the stability of a regular tripod subjected to a load which acts in the direction of its axis of symmetry is presented in this work [1]. In this paper the dificulies for analysis the space structure in detecting the singular point and obtaining the real load carying capacity of these structures has been investigated and finaly a method for overcome to this problem has been presented. The numerical predictions in presented method has been verified with analytical soulotion in a space truss and and Laboratory results in a space frame

Association of TNF-α G308A gene polymorphism in essential hypertensive patients without type 2 diabetes mellitus

This study aims to investigate the effects of tumor necrosis factor alpha (TNF-α) G308A gene polymorphism on essential hypertension (EHT) with or without type 2 diabetes mellitus (T2DM). The project was conducted on buccal epithelial and blood cells for case and control patients, respectively. Epithelial cells were obtained from the inner part of the cheeks. Techniques including DNA extraction, polymerase chain reaction (PCR), and restriction fragment length polymorphism (RFLP) were utilized to assess biomarkers of DNA damage. Our results demonstrated significant differences between wild and mutated genotypes among EHT patients without T2DM. We also found a significant association between wild and mutated allele frequencies in EHT patients (P < 0.05). Clinical characteristics between the groups (EHT with or without T2DM and controls) showed statistically significant association (P < 0.05). Overall, we show that G308A polymorphism of the TNF-αgene may be a significant genetic risk factor for EHT without T2DM patients in Malaysia

Orthogonal Light-Dependent Membrane Adhesion Induces Social Self-Sorting and Member-Specific DNA Communication in Synthetic Cell Communities

Developing orthogonal chemical communication pathways in diverse synthetic cell communities is a considerable challenge due to the increased crosstalk and interference associated with large numbers of different types of sender-receiver pairs. Herein, the authors control which sender-receiver pairs communicate in a three-membered community of synthetic cells through red and blue light illumination. Semipermeable protein-polymer-based synthetic cells (proteinosomes) with complementary membrane-attached protein adhesion communicate through single-stranded DNA oligomers and synergistically process biochemical information within a community consisting of one sender and two different receiver populations. Different pairs of red and blue light-responsive protein-protein interactions act as membrane adhesion mediators between the sender and receivers such that they self-assemble and socially self-sort into different multicellular structures under red and blue light. Consequently, distinct sender-receiver pairs come into the signaling range depending on the light illumination and are able to communicate specifically without activation of the other receiver population. Overall, this work shows how photoswitchable membrane adhesion gives rise to different self-sorting protocell patterns that mediate member-specific DNA-based communication in ternary populations of synthetic cells and provides a step towards the design of orthogonal chemical communication networks in diverse communities of synthetic cells

Grand Challenges: Improving HIV Treatment Outcomes by Integrating Interventions for Co-Morbid Mental Illness.

In the fourth article of a five-part series providing a global perspective on integrating mental health, Sylvia Kaaya and colleagues discuss the importance of integrating mental health interventions into HIV prevention and treatment platforms. Please see later in the article for the Editors' Summary

Influence of Behavioral Patterns on Academic Performance- Comparison between Students of the Morning session and Afternoon session at the College of Health Sciences (CHS), Kingdom of Bahrain.

Three hundred and two Nursing and Allied Health students attending either Morning or Afternoon session at the College of Health Sciences, Kingdom of Bahrain, were compared on their academic performance and behavioral patterns vis-à-vis, eating, sleeping, study time, recreation and family interaction. The questionnaire survey revealed significant differences between the two groups on many variables. A relatively greater proportion of the afternoon session students did not take breakfast and lunch. There was a highly significant difference between the wakeup time on weekdays and holidays. Excluding test days, a mean of 15.62 hours per week of outside class study time was estimated. Recreational activities were mainly sedentary in nature. Students spent 3.84 hours (mean) per day for sedentary recreational activities

Evaluation Of Mechanical and Biocompatibility Properties of Hydroxyapatite/Manganese Dioxide Nanocomposite Scaffolds for Bone Tissue Engineering Application

The aim of this research was to evaluate the mechanical properties, biocompatibility, and degradation behavior of scaffolds made of pure hydroxyapatite (HA) and HA‐modified by MnO2 for bone tissue engineering applications. HA and MnO2 were developed using sol‐gel and precipitation methods, respectively. The scaffolds properties were characterized using X‐ray diffraction (XRD), Fourier transform spectroscopy (FTIR), scanning electron microcopy (SEM), energy dispersive spectroscopy (EDS), and transmission electron microscopy (TEM). The interaction of scaffold with cells was assessed using in vitro cell proliferation and alkaline phosphatase (ALP) assays. The obtained results indicate that the HA/ MnO2 scaffolds possess higher compressive strength, toughness, hardness, and density when compared to the pure HA scaffolds. After immersing the scaffold in the SBF solution, more deposited apatite appeared on the HA/MnO2, which results in the rougher surface on this scaffold compared to the pure HA scaffold. Finally, the in vitro biological analysis using human osteoblast cells reveals that scaffolds are biocompatible with adequate ALP activit