Paradojas circulares. ¿Por qué los observadores difieren cíclicamente de los participadores?

Following the discussion held on pages of the Journal of Ethnographic Theory between Tim Ingold and Alpa Shah, an analysis of the discordance in the participant observation in both components is made. While Ingold sees it as a learning, Shah perceives it as a revolutionary medium. This discordance is perceived in a broader way in all ethnographic experiences. After reviewing the historical origins of the participant observation, it delves into its cyclic discrepancies. For a better understanding of this disintegration, two personal ethnographic examples are used in Israel and Michoacán. It is concluded that we are losing knowledge as professionals thanks to this internal difference.A raíz de la discusión sostenida en páginas del Journal of Ethnographic Theory entre Tim Ingold y Alpa Shah, se hace un análisis de la discordancia en la observación participante en ambos componentes. Mientras Ingold lo ve como un aprendizaje, Shah lo percibe como un medio revolucionario. Esta discordancia se percibe de modo más amplio en todas las experiencias etnográficas. Luego de revisar los orígenes históricos de la observación participante, se adentra en sus discordancias cíclicas. Para mejor comprensión de esta disgregación se utilizan dos ejemplos etnográficos personales en Israel y Michoacán. Se concluye que los profesionales estamos perdiendo conocimientos gracias a esta diferencia interna

Production of microbial transglutaminase on media made from sugar cane molasses and glycerol

Transglutaminase is an enzyme that catalyses an acyl transfer reaction between γ-carboxamide groups of glutaminyl residues and lysine residues in proteins. Due to this property, this enzyme is used for enhancing textural properties of protein-rich food. The transglutaminase used as food additive is obtained by microorganisms, mainly by Streptoverticillium ladakanum. On the other hand, sugar cane molasses is a viscous liquid rich in noncrystallized carbohydrates (saccharose, glucose and fructose). In this work, the feasibility of using sugar cane molasses as a carbon source for the production of microbial transglutaminase by Streptoverticillium ladakanum NRRL 3191 has been studied. Carbon sources including sugar cane molasses (60 g of total sugars per L), glycerol (60 g/L) and their mixture in a ratio of 1:1 (30 g/L of each) were evaluated. Time course of microbial growth, transglutaminase activity and carbon source consumption were determined every 24 h during 120 h of fermentations at three agitation speeds (200, 300 or 400 rpm). The results showed that with the increase in agitation speed, the biomass concentration increased up to 8.39 g/L in the medium containing sugar cane molasses alone or the mixture of molasses and glycerol. The highest transglutaminase activity was obtained at 400 rpm in the medium containing a mixture of molasses and glycerol, reaching 0.460 U/mL, while in the medium containing sugar cane molasses alone, the activity was 0.240 U/mL, and using glycerol alone it was 0.250 U/mL. These results show that sugar cane molasses is a suitable medium for transglutaminase production when it is combined with glycerolA grant from FOMIX CONACYT – Gobierno de Tamaulipas (Ref. 2004/1055) to author Portilla-Rivera is gratefully acknowledged. The authors are grateful to Ministerio de Educación y Ciencia (Spain) for the financial support of this work (Project: AGL2006-08250/ALI)S

Random Generation of Arbitrary Waveforms for Emulating Three-Phase Systems

This paper describes an apparatus for generating a signal representative of steady-state and transient disturbances in three-phase waveforms of an ac electrical system as described in IEEE Std 1159-09. It can be configured as a synthesizer of randomly distorted signals for different applications: for testing the effects of disturbed grid on equipment and to generate patterns of electrical disturbances for the training of artificial neural networks, which are used for measuring power quality tasks. For the first purpose, voltage and current amplifiers are added in the output stage, which allows the generation of disturbed signals at grid level.Comisión Interministerial de Ciencia y Tecnología DPI2006-15467-C02-01Comisión Interministerial de Ciencia y Tecnología DPI2006-15467-C02-0

Do the Historical Biogeography and Evolutionary History of the Digenean Margotrema spp. across Central Mexico Mirror Those of Their Freshwater Fish Hosts (Goodeinae)?

Host-parasite systems provide an ideal platform to study evolution at different levels, including codivergence in a historical biogeography context. In this study we aim to describe biogeographic and codivergent patterns and associated processes of the Goodeinae freshwater fish and their digenean parasite (Margotrema spp.) over the last 6.5 Ma (million years), identifying the main factors (host and/or hydrogeomorphology) that influenced the evolution of Margotrema. We obtained a species tree for Margotrema spp. using DNA sequence data from mitochondrial and nuclear molecular markers (COI and ITS1, respectively) and performed molecular dating to discern divergence events within the genus. The dispersal-extinction-cladogenesis (DEC) model was used to describe the historical biogeography of digeneans and applied to cophylogenetic analyses of Margotrema and their goodeine hosts. Our results showed that the evolutionary history of Margotrema has been shaped in close association with its geographic context, especially with the geological history of central Mexico during the Pleistocene. Host-specificity has been established at three levels of historical association: a) Species-Species, represented by Xenotaenia resolanae -M. resolanae exclusively found in the Cuzalapa River Basin; b) Species-Lineage, represented by Characodon audax-M. bravoae Lineage II, exclusive to the Upper and Middle Mezquital River Basin, and c) Tribe-Lineage, including two instances of historical associations among parasites and hosts at the taxonomical level of tribe, one represented by Ilyodontini-M. bravoae Lineage I (distributed across the Ayuquila and Balsas River Basins), and another comprised of Girardinichthyini/Chapalichthyini-M. bravoae Lineage III, found only in the Lerma River Basin. We show that the evolutionary history of the parasites is, on several occasions, in agreement with the phylogenetic and biogeographic history of their hosts. A series of biogeographic and host-parasite events explain the codivergence patterns observed, in which cospeciation and colonisation via host-switching and vicariant plus dispersal events are appreciated, at different times during the diversification history of both associates, particularly during the Pleistocene.Facultad de Ciencias Naturales y Muse

Tectonic Control on Sedimentary Dynamics in Intraplate Oceanic Settings: A Geomorphological Image of the Eastern Canary Basin and Insights on its Middle-Upper Miocene to Quaternary Volcano-Tectonic-Sedimentary Evolution

This paper integrates sedimentary, tectonic and volcanic geological processes inside a model of volcano-tectonic activity in oceanic intraplate domains related to rifted continental margins. The study case, the eastern Canary Basin (NE Atlantic), is one of the few places in the world where giant MDTs and Quaternary volcanic and hydrothermal edifices take place in intraplate domains. In this paper, we analyse how two structural systems (WNW-ESE and NNE-SSW) matching with the oceanic fabric control the location of volcanic systems, seafloor tectonic reliefs and subsequently the distribution of main sedimentary systems. Linear turbidite channels, debris flow lobes and the lateral continuity of structural and volcanic reliefs follow a WNW-ESE trend matching the tracks of the oceanic fracture zones. Furthermore, escarpments, anticline axes and volcanic ridges follow a NNE-SSW trend matching normal faults delimiting blocks of oceanic basement. The morpho-structural analysis of all the above geomorphological features shows evidence of a volcanic and tectonic activity from the middle–upper Miocene to the Lower–Middle Pleistocene spread over the whole of the eastern Canary Basin that reached the western Canary Islands. This reactivation changes the paradigm in the seamount province of Canary Islands reported inactive since Cretaceous. A tecto-sedimentary model is proposed for this period of time that can be applied in other intraplate domains of the world. A tectonic uplift in the study area with a thermal anomaly triggered volcanic and hydrothermal activity and the subsequent flank collapse and emplacement of mass transport deposits on the Western Canary Slope. Furthermore, this uplift reactivated the normal basement faults, both trending WNW-ESE and NNE-SSW, generating folds and faults that control the location of turbidite channels, escarpments, mass transport deposits and volcanic edifices.Versión del edito

Enzalutamide: a new prostate cancer targeted therapy against the androgen receptor

[Abstract] Enzalutamide (MDV3100), an androgen receptor-signalling inhibitor, represents the most recent compound added to the therapeutic armamentarium for the treatment of metastatic castration-resistant prostate cancer (mCRPC) who progressed to docetaxel. The anti-tumour activity and safety of enzalutamide has been demonstrated in a phase III clinical trial, showing a benefit in overall survival, which was the primary endpoint. There are no head-to-head studies comparing the different treatment options in this subset of patients. In this article, most relevant data published in the literature have been reviewed, with special attention to the therapeutic alternatives currently available for postdocexatel mCRPC patients, emphasising the mechanisms of action of the different drugs, efficacy and quality of life-related aspects

From hyperextended rift to convergent margin types: mapping the outer limit of the extended Continental Shelf of Spain in the Galicia area according UNCLOS Art. 76

European Geosciences Union General Assembly (2017. Viena)Spain presented on 11 May 2009 a partial submission for delimiting the extended Continental Shelf in respect to the area of Galicia to the Commission on the Limits of the Continental Shelf (CLCS). The Galicia margin represents an example of the transition between two different types of continental margins (CM): a western hyperpextended margin and a northern convergent margin in the Bay of Biscay. The western Galicia Margin (wGM 41º to 43º N) corresponds to a hyper-extended rifted margin as result of the poly-phase development of the Iberian-Newfoundland conjugate margin during the Mesozoic. Otherwise, the north Galicia Margin (nGM) is the western end of the Cenozoic subduction of the Bay of Biscay along the north Iberian Margin (NIM) linked to the Pyrenean-Mediterranean collisional belt.Instituto Geológico y Minero de España, EspañaCentro Oceanográfico de Málaga, Instituto Español de Oceanografía, EspañaInstituto Hidrográfico de la Marina, Españ

Biological hydrogen production: trends and perspectives

"Biologically produced hydrogen (biohydrogen) is a valuable gas that is seen as a future energy carrier, since its utilization via combustion or fuel cells produces pure water. Heterotrophic fermentations for biohydrogen production are driven by a wide variety of microorganisms such as strict anaerobes, facultative anaerobes and aerobes kept under anoxic conditions. Substrates such as simple sugars, starch, cellulose, as well as diverse organic waste materials can be used for biohydrogen production. Various bioreactor types have been used and operated under batch and continuous conditions; substantial increases in hydrogen yields have been achieved through optimum design of the bioreactor and fermentation conditions. This review explores the research work carried out in fermentative hydrogen production using organic compounds as substrates. The review also presents the state of the art in novel molecular strategies to improve the hydrogen production.

Environmental quality and equity in the Human Development Index: an integrated index for the Local Agenda 21 case study

Although the Human Development Index (HDI) allows for a more accurate measurement of the real achievements of growth than the gross domestic product, it does not include other necessary variables for human development, such as economic inequality and growth environmental costs. An integrated HDI was developed which included environmental quality and equity as variables, along with income, life expectancy and education. The integrated HDI was applied in the 169 coastal municipalities of Mexico and the results were always lower than the official HDI calculated for the same year. We compared the relationship between the HDI and the integrated HDI with the distribution models of Local Agenda 21 (LA21), which was different for most of the municipalities. Lastly, the components of the integrated HDI for building scenarios were reviewed, prevailing subjects regarding education, health, environmental quality and equity, in order to propose strategies for the development of public policies for the LA21. Keywords: HDI, sustainability, Gini coefficient, coastal municipalities, Mexico, public polic