21 research outputs found
Solid-State Culture for Lignocellulases Production
Aspergillus sp. and Trametes versicolor solid-state monocultures produced high titers of xylanases and laccases activities (4617 ± 38 and 2759 ± 30 U/gsubstrate, respectively). Fungal biomass was quantified by estimating the ergosterol content of the mycelium, and by a simple material balance the corresponding residual substrate was obtained. Fungal growth and substrate consumption rates showed different behavior for these monocultures (μ = 0.03 and 0.11 h−1; rs = − 0.04 and − 0.0006 gsubstrate/h, respectively). In this case, xylanases production was directly linked to the growth, while laccases were produced during both growth and maintenance phases. Besides xylanases (42% of total Aspergillus enzyme), high titers of cellulases (15%), amylases (34%), and invertases (9%), as well as lignin and manganese peroxidases (10 and 24% of the total Trametes enzyme), were produced on the corresponding monocultures. When both fungi were used in a coculture mode, xylanases and laccases production decreased (around 85 and 70%), and the proportion of the hydrolases and oxidases changed. This suggested the need for most careful coculture design, in order to produce both enzymatic activities simultaneously even though the enzymatic extracts obtained by mono- or cocultures can be applied in several bioprocesses
Statistical Profile of the Graduates of the Pharmacy Career in the FES Zaragoza UNAM
Objetivo: Determinar el perfil estadístico de la población de egresados de la carrera Química Farmacéutico
Biológica para las promociones 2005 al 2016.
Método: Fueron evaluados los egresados de las promociones 2005-2009 al 2012-2016. El total de cuestionarios
analizados fue de 289. El instrumento utilizado, cuenta con 93 preguntas de las cuales el 40
porciento son abiertas y 60 por ciento son preguntas cerradas fue validado con un grado de confiabilidad
de alfa de Cronbach de 0.7058. Se utilizó estadística no paramétrica y una descripción gráfica de los
resultados obtenidos.
Resultados: Se determinó el perfil estadístico de los egresados y la trazabilidad de las promociones, en
el mercado laboral, se pudo apreciar también que aproximadamente el 53% de los egresados es laboralmente
activo, y el restante 47% se encuentra realizando tesis profesional, servicio social, estudios de
posgrado, etc… Se pudo determinar salarios de los egresados de esas generaciones, influencia de género
tipo de empresa u organización donde se encuentran realizando actividades profesionales, así como
el grado de concordancia del perfil de egreso de los estudiantes con respecto al perfil requerido por el
mercado de trabajo.
Conclusiones: La metodología permitió obtener información sobre el desempeño de los egresados además,
conocer elementos que favorecen la toma de decisiones respecto a la actualización o modificación
del plan de estudios de la carrera Química Farmacéutico Biológica y sus programas, se sabe ahora que
el perfil profesional del egresado está acorde a las necesidades de los diversos campos, en donde puede
desempeñar sus actividades profesionales.Objective: To determine the statistical profile of the population of graduates of the Biological Pharmaceutical
Chemistry career for promotions 2005 to 2016.
Method: Graduates of the promotions 2005-2009 to 2012-2016 were evaluated. The total number of questionnaires
analyzed was 289. The instrument used, has 93 questions of which 40 percent are open and
60 percent are closed questions was validated with a reliability level of Cronbach’s alpha of 0.7058.
Non-parametric statistics and a graphic description of the results obtained were used.
Results: The statistical profile of the graduates and the traceability of the promotions were determined,
in the labor market, it was also seen that approximately 53% of the graduates are working, and the remaining
47% are doing professional thesis, service social, postgraduate studies, etc ... It was possible to
determine the salaries of the graduates of these generations, gender influence type of company or organization
where they are doing professional activities, as well as the degree of concordance of the profile
of students’ exit with respect to the profile required by the labor market.
Conclusions: The methodology allowed to obtain information about the performance of the graduates
as well as to know elements that favor the decision making regarding the update or modification of the curriculum of the Biological Pharmaceutical Biology career and its
programs, it is now known that the professional profile of the graduate
is according to the needs of the various fields, where you can
play your professional activities
MODELO DE CONCIENCIA PARA LA SUSTENTABILIDAD
Roughly, the conscience for sustainability unveils a process of civil self-management in the face of the
absence or inefficiency of state management in terms of resource supply and quality of public services. In this
sense, the present work set out to establish a model for the study of the phenomenon. Documentary work
was done with a sample selection of sources indexed to national repositories, considering the year of
publication and the keywords. Lines related to the extension of the model, as well as to the comparison
between regions are confirmed to corroborate the findings reported in the literature.Grosso modo, la conciencia para la sustentabilidad devela un proceso de autogestión civil frente a la
ausencia o ineficiencia de la gestión estatal en materia de abastecimiento de recursos y calidad de los
servicios públicos. En ese tenor, el presente trabajo se propuso establecer un modelo para el estudio del
fenómeno. Se realizó un trabajo documental con una selección muestral de fuentes indexadas a repositorios
nacionales, considerando el año de publicación y las palabras claves. Se advierten líneas concernientes a la
extensión del modelo, así como a la comparación entre regiones para corroborar los hallazgos reportados en
la literatura
Habitabilidad y política de vivienda
En esta obra, en la que participan destacados investigadores y profesores, dedicados al estudio de la problemática habitacional se presentan diferentes análisis que permiten conocer cuales son las condiciones de habitabilidad y las características de la actual política de vivienda de México.
En sus capítulos se abordan los principales desafíos que enfrentan las familias mexicanas para acceder a una vivienda digna y decorosa y cuales son los retos económicos, políticos, territoriales, arquitectónicos, ambientales, financieros y culturales de las formas de producción habitacional en México y en otros países, en el marco de una sociedad global
Compilación de Proyectos de Investigacion de 1984-2002
Instituto Politecnico Nacional. UPIICS
Global Impact of the COVID-19 Pandemic on Stroke Volumes and Cerebrovascular Events: One-Year Follow-up.
BACKGROUND AND OBJECTIVES
Declines in stroke admission, intravenous thrombolysis, and mechanical thrombectomy volumes were reported during the first wave of the COVID-19 pandemic. There is a paucity of data on the longer-term effect of the pandemic on stroke volumes over the course of a year and through the second wave of the pandemic. We sought to measure the impact of the COVID-19 pandemic on the volumes of stroke admissions, intracranial hemorrhage (ICH), intravenous thrombolysis (IVT), and mechanical thrombectomy over a one-year period at the onset of the pandemic (March 1, 2020, to February 28, 2021) compared with the immediately preceding year (March 1, 2019, to February 29, 2020).
METHODS
We conducted a longitudinal retrospective study across 6 continents, 56 countries, and 275 stroke centers. We collected volume data for COVID-19 admissions and 4 stroke metrics: ischemic stroke admissions, ICH admissions, intravenous thrombolysis treatments, and mechanical thrombectomy procedures. Diagnoses were identified by their ICD-10 codes or classifications in stroke databases.
RESULTS
There were 148,895 stroke admissions in the one-year immediately before compared to 138,453 admissions during the one-year pandemic, representing a 7% decline (95% confidence interval [95% CI 7.1, 6.9]; p<0.0001). ICH volumes declined from 29,585 to 28,156 (4.8%, [5.1, 4.6]; p<0.0001) and IVT volume from 24,584 to 23,077 (6.1%, [6.4, 5.8]; p<0.0001). Larger declines were observed at high volume compared to low volume centers (all p<0.0001). There was no significant change in mechanical thrombectomy volumes (0.7%, [0.6,0.9]; p=0.49). Stroke was diagnosed in 1.3% [1.31,1.38] of 406,792 COVID-19 hospitalizations. SARS-CoV-2 infection was present in 2.9% ([2.82,2.97], 5,656/195,539) of all stroke hospitalizations.
DISCUSSION
There was a global decline and shift to lower volume centers of stroke admission volumes, ICH volumes, and IVT volumes during the 1st year of the COVID-19 pandemic compared to the prior year. Mechanical thrombectomy volumes were preserved. These results suggest preservation in the stroke care of higher severity of disease through the first pandemic year.
TRIAL REGISTRATION INFORMATION
This study is registered under NCT04934020
Underlying-event properties in pp and p–Pb collisions at √sNN = 5.02 TeV
We report about the properties of the underlying event measured with ALICE at the LHC in pp and p−Pb collisions at sNN−−−√=5.02 TeV. The event activity, quantified by charged-particle number and summed-pT densities, is measured as a function of the leading-particle transverse momentum (ptrigT). These quantities are studied in three azimuthal-angle regions relative to the leading particle in the event: toward, away, and transverse. Results are presented for three different pT thresholds (0.15, 0.5, and 1 GeV/c) at mid-pseudorapidity (|η|10 GeV/c, whereas for lower ptrigT values the event activity is slightly higher in p−Pb than in pp collisions. The measurements are compared with predictions from the PYTHIA 8 and EPOS LHC Monte Carlo event generators
Underlying-event properties in pp and p–Pb collisions at √sNN = 5.02 TeV
We report about the properties of the underlying event measured with ALICE at the LHC in pp and p−Pb collisions at sNN−−−√=5.02 TeV. The event activity, quantified by charged-particle number and summed-pT densities, is measured as a function of the leading-particle transverse momentum (ptrigT). These quantities are studied in three azimuthal-angle regions relative to the leading particle in the event: toward, away, and transverse. Results are presented for three different pT thresholds (0.15, 0.5, and 1 GeV/c) at mid-pseudorapidity (|η|10 GeV/c, whereas for lower ptrigT values the event activity is slightly higher in p−Pb than in pp collisions. The measurements are compared with predictions from the PYTHIA 8 and EPOS LHC Monte Carlo event generators
Measurement of ψ (2S) production as a function of charged-particle pseudorapidity density in pp collisions at √s = 13 TeV and p–Pb collisions at √sNN = 8.16 TeV with ALICE at the LHC
Production of inclusive charmonia in pp collisions at center-of-mass energy of √s = 13 TeV and p–Pb collisions at center-of-mass energy per nucleon pair of √sNN = 8.16 TeV is studied as a function of charged-particle pseudorapidity density with ALICE. Ground and excited charmonium states (J/ψ, ψ(2S)) are measured from their dimuon decays in the interval of rapidity in the center-of-mass frame 2.5 < ycms < 4.0 for pp collisions, and 2.03 < ycms < 3.53 and −4.46 < ycms < −2.96 for p–Pb collisions. The charged-particle pseudorapidity density is measured around midrapidity (|η| < 1.0). In pp collisions, the measured charged-particle multiplicity extends to about six times the average value, while in p-Pb collisions at forward (backward) rapidity a multiplicity corresponding to about three (four) times the average is reached. The ψ(2S) yield increases with the charged-particle pseudorapidity density. The ratio of ψ(2S) over J/ψ yield does not show a significant multiplicity dependence in either colliding system, suggesting a similar behavior of J/ψ and ψ(2S) yields with respect to charged-particle pseudorapidity density. Results for the ψ(2S) yield and its ratio with respect to J/ψ agree with available model calculations