328 research outputs found

    DTMOS-Based 0.4V Ultra Low-Voltage Low-Power VDTA Design and Its Application to EEG Data Processing

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    In this paper, an ultra low-voltage, ultra low-power voltage differencing transconductance amplifier (VDTA) is proposed. DTMOS (Dynamic Threshold Voltage MOS) transistors are employed in the design to effectively use the ultra low supply voltage. The proposed VDTA is composed of two operational transconductance amplifiers operating in the subthreshold region. Using TSMC 0.18µm process technology parameters with symmetric ±0.2V sup¬ply voltage, the total power consumption of the VDTA block is found as just 5.96 nW when the transconductances have 3.3 kHz, 3 dB bandwidth. The proposed VDTA circuit is then used in a fourth-order double-tuned band-pass filter for processing real EEG data measurements. The filter achieves close to 64 dB dynamic range at 2% THD with a total power consumption of 12.7 nW

    The determination of the pituitary gland, optic chiasm, and intercavernous distance measurements in healthy subjects according to age and gender

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    Background: This paper was undertaken to determine the morphometry of pituitary gland diameter, pituitary gland height, intercavernous distance, optic chiasm diameter and optic chiasm height in skulls of Turkish population aged between 18 and 60 years. Materials and methods: It was a retrospective study in which 292 subjects were included 187 females and 105 males, ranging from 18 up to 60 years. Subjects underwent brain magnetic resonance imaging in the Radiology Department. Statistical analysis was performed with SPSS 21.00 programme. ANOVA test, χ2 test, and Pearson correlation analysis were used to determine the relation and significance between measurements and age group. The p < 0.05 value was considered as significant. Results: The groups were divided into five groups according to age. The overall means and standard deviations of the measurements were: pituitary gland width, 13.09 ± 1.99 mm; pituitary gland height, 4.91 ± 1.10 mm; intercavernous distance, 15.93 ± 3.05 mm; optic chiasm width, 12.82 ± 1.27 mm; and optic chiasm height, 2.80 ± 0.49 mm in females, respectively whereas, the same measurements were 12.96 ± 1.74 mm; 4.79 ± 0.95 mm; 16.08 ± 3.11 mm; 13.13 ± 1.37 mm; 2.86 ± 0.70 mm in males, respectively. Height of the pituitary gland reached a maximum in the age group of 18 to 20 years in both females and males and there was a decrease in the pituitary gland height in the subsequent age groups. Conclusions: Knowledge of the variation in the size of pituitary gland, intercavernous distance and optic chiasm is important to evaluate the dimensions of these structures for clinical and pathological processes

    A wideband linear tunable CDTA and its application in field programmable analogue array

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    This document is the Accepted Manuscript version of the following article: Hu, Z., Wang, C., Sun, J. et al. ‘A wideband linear tunable CDTA and its application in field programmable analogue array’, Analog Integrated Circuits and Signal Processing, Vol. 88 (3): 465-483, September 2016. Under embargo. Embargo end date: 6 June 2017. The final publication is available at Springer via https://link.springer.com/article/10.1007%2Fs10470-016-0772-7 © Springer Science+Business Media New York 2016In this paper, a NMOS-based wideband low power and linear tunable transconductance current differencing transconductance amplifier (CDTA) is presented. Based on the NMOS CDTA, a novel simple and easily reconfigurable configurable analogue block (CAB) is designed. Moreover, using the novel CAB, a simple and versatile butterfly-shaped FPAA structure is introduced. The FPAA consists of six identical CABs, and it could realize six order current-mode low pass filter, second order current-mode universal filter, current-mode quadrature oscillator, current-mode multi-phase oscillator and current-mode multiplier for analog signal processing. The Cadence IC Design Tools 5.1.41 post-layout simulation and measurement results are included to confirm the theory.Peer reviewedFinal Accepted Versio

    Investigation of Changes in Mechanical Properties and Microstructures of Mild Steel Joint by Oxy-Hydrogen Welding

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    In this paper, in order to see weldability behaviour of mild steels joint by the oxy-hydrogen welding technique, an investigation of changes in mechanical properties and microstructures of mild steel is carried out. The specimens with 1.5 mm thickness and 125 mm length are welded by using both the oxyhydrogen and oxy-acetylene gases. Microstructural analysis is carried out on the cross sectional area of the welding zone in order to compare the changes in weld metals and the heat affected zones in terms of the welding gases. Experimental results of the tensile strength and microhardness obtained with mechanical tests show that samples welded with oxy-acetylene exhibited 10% higher yield strength than that of the samples welded with oxy-hydrogen. However, the oxy-hydrogen welding technique can be used as an alternative to the oxy-acetylene welding, since it has advantageous of being clean and economic.С целью выяснения качества сварного шва на малоуглеродистой стали, полученного водород-кислородной сваркой, проведено исследование изменений механических свойств и микроструктуры данного типа стали. Образцы толщиной 1,5 мм и длиной 125 мм сваривались как водород-кислородной, так и ацетиленокислородной сваркой. Был проведён микроструктурный анализ поперечного сечения зоны сварки с целью сравнения изменений в металле шва и зоне термического влияния в зависимости от сварочного газа. Экспериментальные результаты по пределу прочности при растяжении и микротвёрдости, полученные при механических испытаниях, показали, что образцы, сваренные ацетиленокислородной сваркой, имеют прочность при растяжении на 10% выше, чем водород-кислородной. Однако водород-кислородная сварка может быть использована как альтернатива ацетиленокислородной сварке, так как она имеет преимущества по чистоте и экономичности.З метою з’ясування якости зварюваного шва на маловуглецевій сталі, виробленого водневокисневим зварюванням, виконано дослідження змін механічних властивостей і мікроструктури даного типу сталі. Зразки товщиною у 1,5 мм та довжиною у 125 мм зварювалися як водневокисневим, так і ацетиленокисневим зварюванням. Виконано мікроструктурну аналізу поперечного перерізу зони зварювання з метою порівняння змін у металі шва та зоні термічного впливу в залежності від зварювального газу. Експериментальні результати стосовно границі міцности при розтягу та мікротвердости, одержані під час механічних випробувань, показали, що зразки, зварені ацетиленокисневим зварюванням, мають міцність при розтягу, на 10% вищу, ніж зварені водневокисневою газовою сумішшю. Однак водневокисневе зварювання може бути використано як альтернатива ацетиленокисневому зварюванню завдяки його перевазі за чистотою та економічністю

    Capital Fixity and Mobility in Response to the 2008-09 Crisis: Variegated Neoliberalism in Mexico and Turkey

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    The article examines the 2008-9 crisis responses in Mexico and Turkey as examples of variegated neoliberalism. The simultaneous interests of corporations and banks relative to the national fixing of capital and their mobility in the form of global investment heavily influenced each state authority’s policy responses to the crisis at the expense of the interests of the poor, workers, and peasantry. Rather than pitching this as either evidence of persistent national differentiation or some Keynesian state resurgence, we argue from a historical materialist geographical framework that the responses of capital and state authorities in Mexico and Turkey actively constitute and reconstitute the global parameters of market regulatory design and neoliberal class rule through each state’s distinct domestic policy formation and crisis management processes. While differing in specific content the form of Mexico and Turkey’s state responses to the crisis ensured continuity in their foregoing neoliberal strategies of development and capital accumulation, most notably in the continued oppression of workers. That is, the prevailing strategy of accumulation continues to be variegated neoliberalism

    Effect of Mill Type on Morphology of AA6013 Aluminium Powder

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    ABSTRACTIn conventional recycling method, metal chips are cast after pressing and melting in electric arc furnace. Material loss occurs during the recycling from liquid metal due to the several reasons. Direct recycling method which produces the aluminium powder from aluminium chips using mechanical mill can be an alternative to conventional recycling method. Thus material and energy losses, and labour cost will be reduced by direct recycling method without melting.In this study, the particle morphology of powder direct recycled from AA6013 aluminium alloy chips with cryogenic, disc and ball type grinders is investigated. Mechanical milling resulted flaky and irregular shaped AA6013 particles. It was ascertained that the chips did not break sufficiently in despite of the long duration milling mechanisms by ball mill. Cryogenic mill provides the energy required for milling mechanisms to act. Disc mill has the highest impact energy was determined. Consequently, efficiency of ball mill is lower than the efficiency of cryogenic and disc type mills. Shape factors of powders produced with ball and cryogenic mills were found greater than that of the powder produced by disc mill. Disc mill has the most efficient and effective impact energy which produces the smaller particles per minute, was determined.Keywords: Direct recycling method, powder production, scrap chips, aluminium alloy.

    Standards of care for medical management of acromegaly in pituitary tumor centers of excellence (PTCOE)

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    Purpose: A series of consensus guidelines on medical treatment of acromegaly have been produced in the last two decades. However, little information is available on their application in clinical practice. Furthermore, international standards of acromegaly care have not been published. The aim of our study was to report current standards of care for medical therapy of acromegaly, using results collected through an audit performed to validate criteria for definition of Pituitary Tumor Centers of Excellence (PTCOE). Methods: Details of medical treatment approaches to acromegaly were voluntarily provided by nine renowned international centers that participated in this audit. For the period 2018–2020, we assessed overall number of acromegaly patients under medical treatment, distribution of patients on different treatment modalities, overall biochemical control rate with medical therapy, and specific control rates for different medical treatment options. Results: Median number of total patients and median number of new patients with acromegaly managed annually in the endocrinology units of the centers were 206 and 16.3, respectively. Median percentage of acromegaly patients on medical treatment was 48.9%. Among the patients on medical treatment, first-generation somatostatin receptor ligand (SRL) monotherapy was used with a median rate of 48.7%, followed by combination therapies with a median rate of 29.3%. Cabergoline monotherapy was used in 6.9% of patients. Pegvisomant monotherapy was used in 7 centers and pasireotide monotherapy in 5 centers, with median rates of 7.9% and 6.3%, respectively. Conclusions: Current standards of care in PTCOEs include use of first-generation SRLs as the first medical option in about 50% of patients, as recommended by consensus guidelines. However, some patients are kept on this treatment despite inadequate control suggesting that cost-effectiveness, availability, patient preference, side effects, and therapeutic inertia may play a possible role also in PTCOE. Moreover, at odds with consensus guidelines, other monotherapies for acromegaly appear to have a marginal role as compared to combination therapies as extrapolated from PTCOE practice data. Presence of uncontrolled patients in each treatment category suggest that further optimization of medical therapy, as well as use of other therapeutic tools such as radiosurgery may be needed
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