"Identidad en crisis y estética de la fragmentariedad en la novela de Roberto Bolaño"

Este trabajo analiza las formas que adopta la crisis de la identidad, elemento esencial de la literatura posmoderna, en las principales novelas de Roberto Bolaño (La literatura nazi en América, Estrella distante, Los detectives salvajes, Amuleto, Nocturno de Chile y 2666), tanto a nivel temático como estructural. Dicha crisis se convierte en el eje vertebrador de motivos como el doble, el viaje o la locura, y de una concepción novelística que cuestiona sus propios mecanismos, dando lugar a una "estética de la fragmentariedad", a relatos polifónicos y múltiples que a partir de las simetrías se integran en una estructura globalizadora.Aquest treball analitza les formes que adopta la crisi de la identitat, element fonamental de la literatura posmoderna, a les principals novel·les de Roberto Bolaño (La literatura nazi en América, Estrella distante, Los detectives salvajes, Amuleto, Nocturno de Chile i 2666), tant a nivell temàtic com estructural. Aquesta crisi esdevé l'eix vertebrador de motius com el doble, el viatge o la bogeria, i d'una concepció novel·lística que qüestiona els seus mecanismes i dóna lloc a una "estètica de la fragmentarietat", a relats polifònics i múltiples que a partir de les simetries s'integren en una estructura globalitzadora

El laboratorio de inmunología en el diagnóstico y control de las enfermedades autoinmunitarias sistémicas (I): protocolo de estudio ante la sospecha clínica

Inclou referències bibliogràfique

La Llama

De cada obra s'ha digitalitzat un programa sencer. De la resta s'han digitalitzat les parts que són diferents.Director: José Sabater ; director d'escena: Lorenzo Malvet ; escenografies d'Oleguer JunyentEmpresa: José Rode

Rate and duration of hospitalisation for acute pulmonary embolism in the real-world clinical practice of different countries : Analysis from the RIETE registry

publishersversionPeer reviewe

The management of acute venous thromboembolism in clinical practice. Results from the European PREFER in VTE Registry

Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in Europe. Data from real-world registries are necessary, as clinical trials do not represent the full spectrum of VTE patients seen in clinical practice. We aimed to document the epidemiology, management and outcomes of VTE using data from a large, observational database. PREFER in VTE was an international, non-interventional disease registry conducted between January 2013 and July 2015 in primary and secondary care across seven European countries. Consecutive patients with acute VTE were documented and followed up over 12 months. PREFER in VTE included 3,455 patients with a mean age of 60.8 ± 17.0 years. Overall, 53.0 % were male. The majority of patients were assessed in the hospital setting as inpatients or outpatients (78.5 %). The diagnosis was deep-vein thrombosis (DVT) in 59.5 % and pulmonary embolism (PE) in 40.5 %. The most common comorbidities were the various types of cardiovascular disease (excluding hypertension; 45.5 %), hypertension (42.3 %) and dyslipidaemia (21.1 %). Following the index VTE, a large proportion of patients received initial therapy with heparin (73.2 %), almost half received a vitamin K antagonist (48.7 %) and nearly a quarter received a DOAC (24.5 %). Almost a quarter of all presentations were for recurrent VTE, with >80 % of previous episodes having occurred more than 12 months prior to baseline. In conclusion, PREFER in VTE has provided contemporary insights into VTE patients and their real-world management, including their baseline characteristics, risk factors, disease history, symptoms and signs, initial therapy and outcomes

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Heated thin film gauge arrangements to reduce uncertainty in transient heat transfer measurements

This paper describes the development of heated double-sided thin film gauge configurations for transient heat transfer measurements. By heating the substrate it is possible to measure the heat flux over a range of surface temperatures and deduce the adiabatic wall temperature and the external heat transfer coefficient. The accuracy of the measurement depends on the stability of the regression of heat flux against wall temperature and can be improved by extending the range of wall temperature over which the regression is performed. In this paper we compare two methods of local heating: double-sided gauges with an underside thin film heater and self-heating double-sided gauges. Both arrangements have been used in the Oxford Turbine Research Facility to measure the heat transfer on the uncooled turbine shroud of the MT1 high-pressure turbine stage at engine-representative conditions. These measurements yield improved regressions compared to conventional techniques to determine the adiabatic wall temperature and the heat transfer coefficient

TRANSONIC TURBINE BLADE TIP AERO-THERMAL PERFORMANCE WITH DIFFERENT TIP GAPS: PART II-TIP AERODYNAMIC LOSS

Blade tip aerodynamic loss results from experimental and numerical investigations are presented for engine representative conditions downstream of a blade row with an exit Mach number Mexit of 1.0, and an exit Reynolds number Reexit of 1.27x106 (based on axial chord). These results are presented for three different tip gaps of 0.5, 1.0, and 1.5 percent relative to engine-equivalent blade span. Experimental data are obtained by traversing a specially-made and calibrated three-hole pressure probe as well as a single-hole probe one axial chord downstream of the blade within the Oxford High Speed Linear Cascade research facility. Three-dimensional RANS CFD numerical predictions are conducted using the Rolls-Royce HYDRA numerical prediction code for steady flow with the Spalart-Allmaras (SA) turbulence model. Included are detailed distributions of stagnation pressure losses, and pitch-wise flow angle. Local total pressure data and mass-averaged total pressure loss coefficients show that the strength of the tip leakage vortex decreases as the tip gap decreases. Magnitudes of the pitch-wise flow angle increase within over-tip leakage vortices, as these vortices become stronger and the tip leakage flow increases. The most important difference between experimental and numerical results is in relation to the passage vortex signatures, which are more apparent for all three tip gap values within the numerical results. The effects of relative casing motion and tip clearance are also examined and discussed, and show that the relative casing movement has a relatively small impact on the size of the over-tip leakage vortex at the medium (1.0% of span) and large (1.5% of span) tip gaps, with more noticeable impact at the smallest tip gap (0.5% of span). Copyright © 2010 by ASME