Restoration of error-diffused images using projection onto convex sets

In this paper, a novel inverse halftoning method is proposed to restore a continuous tone image from a given half-tone image. A set theoretic formulation is used where three sets are defined using the prior information about the problem. A new space-domain projection is introduced assuming the halftoning is performed using error diffusion, and the error diffusion filter kernel is known. The space-domain, frequency-domain, and space-scale domain projections are used alternately to obtain a feasible solution for the inverse halftoning problem which does not have a unique solution

QR-RLS algorithm for error diffusion of color images

Printing color images on color printers and displaying them on computer monitors requires a significant reduction of physically distinct colors, which causes degradation in image quality. An efficient method to improve the display quality of a quantized image is error diffusion, which works by distributing the previous quantization errors to neighboring pixels, exploiting the eye's averaging of colors in the neighborhood of the point of interest. This creates the illusion of more colors. A new error diffusion method is presented in which the adaptive recursive least-squares (RLS) algorithm is used. This algorithm provides local optimization of the error diffusion filter along with smoothing of the filter coefficients in a neighborhood. To improve the performance, a diagonal scan is used in processing the image

Lumen Border Detection of Intravascular Ultrasound via Denoising of Directional Wavelet Representations

In this paper, intravascular ultrasound (IVUS) grayscale images, acquired with a single-element mechanically rotating transducer, are processed with wavelet denoising and region-based segmentation to extract various layers of lumen contours and plaques. First, IVUS volumetric data is expanded on complex exponential wavelet-like basis functions, also known as Brushlets, which are well localized in time and frequency domains. Brushlets denoising have demonstrated in the past a great aptitude for denoising ultrasound data and removal of blood speckles. A region-based segmentation framework is then applied for detection of lumen border layers, which remains one of the most challenging problems in IVUS image analysis for images acquired with a single element, mechanically rotating 45 MHz transducer. We evaluated hard thresholding for Brushlet denoising, and compared segmentation results to manually traced lumen borders. We observed good agreement and suggest that the proposed algorithm has a great potential to be used as a reliable pre-processing step for accurate lumen border detection

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiovascular risk—changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million–4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.</p

Global Retinoblastoma Presentation and Analysis by National Income Level

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4) were female. Most patients (n = 3685 84.7%) were from low-and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 62.8%), followed by strabismus (n = 429 10.2%) and proptosis (n = 309 7.4%). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 95% CI, 12.94-24.80, and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 95% CI, 4.30-7.68). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs. © 2020 American Medical Association. All rights reserved

A century of trends in adult human height

Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5-22.7) and 16.5 cm (13.3-19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8-144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries

Repositioning of the global epicentre of non-optimal cholesterol

High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol�which is a marker of cardiovascular risk�changed from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95 credible interval 3.7 million�4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world. © 2020, The Author(s), under exclusive licence to Springer Nature Limited

Effects of mycorrhiza and irrigation programs on strawberry production in substrate culture

The study was conducted in order to determine the effects of mycorrhiza use in two irrigation programs on yield, fruit quality and water consumption of strawberry plants ('Kabarla') grown in perlite. The experiment was carried out during the winter season of 2016 in a PE covered bitunnel at the Department of Horticulture, Faculty of Agriculture at Ege University. In mycorrhiza treatment, ERS (endo roots soluble) was used as mycorrhizal source (0.250 g m-2) and has been applied as dipping of seedling roots before the planting. The plants were irrigated according to the integrated indoor solar radiation levels of 1 or 2 MJ m-2. The amount of irrigation was based on the leaching rate of 30-40% in both treatments. Treatment without mycorrhiza and 1 MJ m-2 were evaluated as control. Experimental design was randomized blocks with 3 replications. Our results indicated that irrigation and mycorrhiza treatments affected total yield and some fruit quality parameters. Fruit firmness, EC of fruit juice and total soluble solids increased and water consumption changed significantly. It was concluded that mycorrhiza application increased total and marketable yields and water use efficiency especially in 2 MJ m-2,. © 2020 International Society for Horticultural Science. All rights reserved

Effects of beneficial microorganisms on organic lettuce growing

This study was conducted in order to determine the effects of beneficial microorganisms on two lettuce cultivars ('Maritima' and 'Patagonia') in organic production. Two beneficial microorganisms, namely mycorrhiza (Glomus spp.) and Trichoderma harzianum stain KRL-AG2 and their combination (mycorrhiza + T. harzianum) were tested comparing with the control (no treatment). Lettuce (Lactuca sativa L.) plants were grown between 14.11.2016 and 02.03.2017 in an unheated greenhouse with a plant density of 5.7 plant m-2. At the end of the growing period, yield and head quality parameters such lettuce size, color, vitamin C and nitrate contents were determined. The results showed that cultivar 'Patagonia' gave the highest yield (2.18 kg m-2) and highest head size (366.16 g m-2), however among the tested microorganisms, mycorrhiza had higher performance as beneficial microorganism compared with the other treatments. © 2020 International Society for Horticultural Science. All rights reserved